Study on the action mechanism of inflammatory mediators generated by the severe acute pancreatitis （SAP） in multiple organ injury is a hotspot in the surgical field. In clinical practice, the main complicated organ ...Study on the action mechanism of inflammatory mediators generated by the severe acute pancreatitis （SAP） in multiple organ injury is a hotspot in the surgical field. In clinical practice, the main complicated organ dysfunctions are shock, respiratory failure, renal failure, encephalopathy, with the rate of hepatic diseases being closely next to them. The hepatic injury caused by SAP cannot only aggravate the state of pancreatitis, but also develop into hepatic failure and cause patient death, lts complicated pathogenic mechanism is an obstacle in clinical treatment. Among many pathogenic factors, the changes of vasoactive substances, participation of inflammatory mediators as well as OFR （oxygen free radical）, endotoxin, etc. may play important roles in its progression.展开更多
The （1＋1）-dimensional F-expansion technique and the homogeneous nonlinear balance principle have been generalized and applied for solving exact solutions to a general （3＋1）-dimensional nonlinear Schr6dinger equa...The （1＋1）-dimensional F-expansion technique and the homogeneous nonlinear balance principle have been generalized and applied for solving exact solutions to a general （3＋1）-dimensional nonlinear Schr6dinger equation （NLSE） with varying coefficients and a harmonica potential. We found that there exist two kinds of soliton solutions. The evolution features of exact solutions have been numerically studied. The （3＋1）D soliton solutions may help us to understand the nonlinear wave propagation in the nonlinear media such as classical optical waves and the matter waves of the Bose-Einstein condensates.展开更多
A numerical study based on direct thermal to electric energy conversion was performed in a reciprocal flow porous media burner embedded with two layers of thermoelements. The burner lean combustibility limit was sough...A numerical study based on direct thermal to electric energy conversion was performed in a reciprocal flow porous media burner embedded with two layers of thermoelements. The burner lean combustibility limit was sought in order to maximize global efficiency of thermal to electrical energy conversion by minimizing fuel consumption. Once the pairs of operational variables, composition and filtrational velocity of gas inlet mixture were found, the optimal length and placement of thermoelectric elements within the reactor high thermal gradients were sought to maximize the electric current, thermoelements and system overall efficiency. A two temperature-resistance model for finite time thermodynamics was developed for the thermoelectric elements energy fluxes. Results indicate a distribution of current and efficiencies that presents a maximum at different themoelements length. Maximum values for current and system efficiency obtained were 44.3 m A and 2.5%, respectively.展开更多
Based on the flux equivalent principle of a single fracture, the discrete fracture concept was developed, in which the macroscopic fractures are explicitly described as （n-l） dimensional geometry element. On the fun...Based on the flux equivalent principle of a single fracture, the discrete fracture concept was developed, in which the macroscopic fractures are explicitly described as （n-l） dimensional geometry element. On the fundamental of this simplification, the discrete-fractured model was developed which is suitable for all types of fractured porous media. The principle of discrete-fractured model was introduced in detail, and the general mathematical model was expressed subsequently. The fully coupling discrete-fractured mathematical model was implemented using Galerkin finite element method. The validity and accuracy of the model were shown through the Buckley-Leverett problem in a single fracture. Then the discrete-fractured model was applied to the two different type fractured porous media. The effect of fractures on the water flooding in fractured reservoirs was investigated. The numerical results showed that the fractures made the porous media more heterogeneous and anisotropic, and that the orientation, size, type of fracture and the connectivity of fractures network have important impacts on the two-phase flow.展开更多
A novel laboratory experimental design is described that will investigate the processing of dust grains in astrophysical shocks. Dust is a ubiquitous ingredient in the interstellar medium(ISM) of galaxies; however, it...A novel laboratory experimental design is described that will investigate the processing of dust grains in astrophysical shocks. Dust is a ubiquitous ingredient in the interstellar medium(ISM) of galaxies; however, its evolutionary cycle is still poorly understood. Especially shrouded in mystery is the efficiency of grain destruction by astrophysical shocks generated by expanding supernova remnants. While the evolution of these remnants is fairly well understood, the grain destruction efficiency in these shocks is largely unknown. The experiments described herein will fill this knowledge gap by studying the dust destruction efficiencies for shock velocities in the range ～10–30 km/s(μm/ns), at which most of the grain destruction and processing in the ISM takes place. The experiments focus on the study of grain–grain collisions by accelerating small(～1 μm) dust particles into a large(～5–10 μm diameter) population; this simulates the astrophysical system well in that the more numerous, small grains impact and collide with the large population. Facilities that combine the versatility of high-power optical lasers with the diagnostic capabilities of X-ray free-electron lasers, e.g., the Matter in Extreme Conditions instrument at the SLAC National Accelerator Laboratory, provide an ideal laboratory environment to create and diagnose dust destruction by astrophysically relevant shocks at the micron scale.展开更多
基金Project supported by the Administration of Traditional Chinese Medicine of Zhejiang Province (Nos. 2003C130 and 2004C142)the Medical Science and Technology of Health Department of Zhejiang Province (No. 2003B134)the Technology and Development of Technological Bureau of Hangzhou (No. 2003123B19), China
文摘Study on the action mechanism of inflammatory mediators generated by the severe acute pancreatitis （SAP） in multiple organ injury is a hotspot in the surgical field. In clinical practice, the main complicated organ dysfunctions are shock, respiratory failure, renal failure, encephalopathy, with the rate of hepatic diseases being closely next to them. The hepatic injury caused by SAP cannot only aggravate the state of pancreatitis, but also develop into hepatic failure and cause patient death, lts complicated pathogenic mechanism is an obstacle in clinical treatment. Among many pathogenic factors, the changes of vasoactive substances, participation of inflammatory mediators as well as OFR （oxygen free radical）, endotoxin, etc. may play important roles in its progression.
基金Supported by National Science Foundation of China under Grant No. 2006CB921605
文摘The （1＋1）-dimensional F-expansion technique and the homogeneous nonlinear balance principle have been generalized and applied for solving exact solutions to a general （3＋1）-dimensional nonlinear Schr6dinger equation （NLSE） with varying coefficients and a harmonica potential. We found that there exist two kinds of soliton solutions. The evolution features of exact solutions have been numerically studied. The （3＋1）D soliton solutions may help us to understand the nonlinear wave propagation in the nonlinear media such as classical optical waves and the matter waves of the Bose-Einstein condensates.
文摘A numerical study based on direct thermal to electric energy conversion was performed in a reciprocal flow porous media burner embedded with two layers of thermoelements. The burner lean combustibility limit was sought in order to maximize global efficiency of thermal to electrical energy conversion by minimizing fuel consumption. Once the pairs of operational variables, composition and filtrational velocity of gas inlet mixture were found, the optimal length and placement of thermoelectric elements within the reactor high thermal gradients were sought to maximize the electric current, thermoelements and system overall efficiency. A two temperature-resistance model for finite time thermodynamics was developed for the thermoelectric elements energy fluxes. Results indicate a distribution of current and efficiencies that presents a maximum at different themoelements length. Maximum values for current and system efficiency obtained were 44.3 m A and 2.5%, respectively.
基金supported by the National Basic Research Program of China("973"Program)(Grant No.2011CB20100)the Important National Science and Technology Project of China(Grant No.2011ZX05014- 005-003HZ)+1 种基金the Specialized Research Fund for the Doctoral Program of Higher Education of China(Grant No.20090133110006)the Fundamental Research Funds for the Central Universities(Grant No. 09CX04005A)
文摘Based on the flux equivalent principle of a single fracture, the discrete fracture concept was developed, in which the macroscopic fractures are explicitly described as （n-l） dimensional geometry element. On the fundamental of this simplification, the discrete-fractured model was developed which is suitable for all types of fractured porous media. The principle of discrete-fractured model was introduced in detail, and the general mathematical model was expressed subsequently. The fully coupling discrete-fractured mathematical model was implemented using Galerkin finite element method. The validity and accuracy of the model were shown through the Buckley-Leverett problem in a single fracture. Then the discrete-fractured model was applied to the two different type fractured porous media. The effect of fractures on the water flooding in fractured reservoirs was investigated. The numerical results showed that the fractures made the porous media more heterogeneous and anisotropic, and that the orientation, size, type of fracture and the connectivity of fractures network have important impacts on the two-phase flow.
基金funded by the US Department of Energy, through the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, grant number DE-NA0001840support for this work was provided by NASA through Einstein Postdoctoral Fellowship grant number PF3-140111 awarded by the Chandra X-ray Center
文摘A novel laboratory experimental design is described that will investigate the processing of dust grains in astrophysical shocks. Dust is a ubiquitous ingredient in the interstellar medium(ISM) of galaxies; however, its evolutionary cycle is still poorly understood. Especially shrouded in mystery is the efficiency of grain destruction by astrophysical shocks generated by expanding supernova remnants. While the evolution of these remnants is fairly well understood, the grain destruction efficiency in these shocks is largely unknown. The experiments described herein will fill this knowledge gap by studying the dust destruction efficiencies for shock velocities in the range ～10–30 km/s(μm/ns), at which most of the grain destruction and processing in the ISM takes place. The experiments focus on the study of grain–grain collisions by accelerating small(～1 μm) dust particles into a large(～5–10 μm diameter) population; this simulates the astrophysical system well in that the more numerous, small grains impact and collide with the large population. Facilities that combine the versatility of high-power optical lasers with the diagnostic capabilities of X-ray free-electron lasers, e.g., the Matter in Extreme Conditions instrument at the SLAC National Accelerator Laboratory, provide an ideal laboratory environment to create and diagnose dust destruction by astrophysically relevant shocks at the micron scale.
