End-functionalization of polydiene rubbers can not only improve its compatibility with inorganic fillers,but also enhance the overall mechanical properties.Nevertheless,for traditional neodymium(Nd)diene polymerizatio...End-functionalization of polydiene rubbers can not only improve its compatibility with inorganic fillers,but also enhance the overall mechanical properties.Nevertheless,for traditional neodymium(Nd)diene polymerization systems,it is highly challenging to achieve such end-functionalizations,because most of polydienyl chains are capped withη3-allyl-Nd moiety during the end of polymerization,which shows very poor reactivity with nucleophile compounds.We launched a new diene polymerization strategy calling coordinative chain transfer polymerization(CCTP)[1].In such a system,all the polydienyl chains are capped withη1-allyl-Al moieties,which reveal greater reactivity with cyclic esters and epoxide compounds,providing an effective manner to prepare polydiene-polyester amphiphilic block copolymers.Inspired by such findings,we now show herein how such types of chain-ends react with isot-hiocyanate to demonstrate an efficient in-situ manner to access end-functionalized polydienes by using CCTP.展开更多
[Objective] To examine the effect of endophytic fungi ALl2 （Gilmaniella sp.） on metabolites distribution in organs of Atractylodes lancea. [Method] Endophytic fungi ALl2 was inoculated on Atraetylodes lancea plantle...[Objective] To examine the effect of endophytic fungi ALl2 （Gilmaniella sp.） on metabolites distribution in organs of Atractylodes lancea. [Method] Endophytic fungi ALl2 was inoculated on Atraetylodes lancea plantlets in tissue culture, and the distribution of cellulose, hemicellulose, lignin, soluble sugar in leaves and roots of the inoculated group were detected. The weight of leaves and roots were compared. Gas Chromatography was used to analyze the volatile oil components. [Result] Compared with the control group, the average fresh weight and dry weight of leaves and roots of A. lancea which had been symbiosed with ALl2 increased significantly. The content of lignin and soluble sugar increased in the leaves of the inoculated group, and the content of cellulose, hemicellulose, lignin, soluble sugar and volatile oil also increased in roots. [Conclusion] The results indicate that symbiosed with ALl2 is benefit for the development of A. lancea roots and can promote the transfer and accumulation of the medicinal components to the roots.展开更多
Aim Syntheses of benzodioxane neolignans. Method The SN2 reaction and Corey-Fuchs reaction was used to synthesize Rodgersinine A, 4-[3-methyl-7-[（E）-1-propenyl-2, 3-dihydro-1, 4-benzodioxin-2-yl]-l, 2-benzenediol （...Aim Syntheses of benzodioxane neolignans. Method The SN2 reaction and Corey-Fuchs reaction was used to synthesize Rodgersinine A, 4-[3-methyl-7-[（E）-1-propenyl-2, 3-dihydro-1, 4-benzodioxin-2-yl]-l, 2-benzenediol （1） and Rodgersinine B, 4- [3-methyl- 7-（1-propynyl）-2, 3-dihydro- 1, 4-benzodioxin-2-yl]-0, 2-benzenediol （2）. Results Total synthesis ofRodgersinine A and B was first completed. Conclusion A useful method for constructing benzodioxane neolignans by the SN2 reaction is achieved.展开更多
The spleen could be considered a neglected organ.To date,it has been deemed an ancillary organ in portal hypertension or an organ localization in lymphoproliferative diseases,even though it has had significant attenti...The spleen could be considered a neglected organ.To date,it has been deemed an ancillary organ in portal hypertension or an organ localization in lymphoproliferative diseases,even though it has had significant attention in infectious diseases for some time.Now,it is thought to be central in regulating the immune system,a metabolic asset and involved in endocrine function with regard to nonalcoholic fatty liver disease.The main mechanisms involved in this complex network will be critically discussed in this article.展开更多
A sensory substitution device （SSD） is a technology that translates information for one sensory modality, like vision, into information for use by another, like touch. Though SSDs have been in existence for over fou...A sensory substitution device （SSD） is a technology that translates information for one sensory modality, like vision, into information for use by another, like touch. Though SSDs have been in existence for over four decades, effective training techniques for their use are rarely discussed. In this paper, we compare three training strategies on a particular SSD known as the vOICe. These comparisons were conducted using a minimal but active search and localization task of luminescent discs. These studies show that an interactive training paradigm, which combines the efforts of two trainees at the same time in a tag-like game, is more effective than passive training at a computer console or active training involving search and localization of luminescent discs. This finding supports philosophical views of perception that take interaction with the environment seriously. In particular, we argue that these findings are in support of certain features of the extended mind view as proposed by Andy Clark （2008）. In particular, the study suggests that when environmental conditions are responsive to one＇s behavioral activity, the activity itself is enhanced, as is predicted by the extended mind view.展开更多
AIM: To investigate the tissue distribution, urinary and fecal excretions of 125I-lidamycin (125I-C-1027) in mice and its biliary excretion in rats. METHODS:The total radioactivity assay (RA method) and the radioactiv...AIM: To investigate the tissue distribution, urinary and fecal excretions of 125I-lidamycin (125I-C-1027) in mice and its biliary excretion in rats. METHODS:The total radioactivity assay (RA method) and the radioactivity assay after precipitation with 200 mL/L trichloroacetic add (TCA-RA method) were used to dete-rmine the tissue distribution,and the urinary and fecal excretions of 125I-C-1027 in mice and its biliary excretion in rats. RESULTS:Tissue concentrations reached the peak at the fifth minute after administration of 125I-C-1027 to mice. The highest concentration was in kidney, and the lowest in brain at all test-time points. The organs of the concentrations of 125I-C-1027 from high to low were kidney, lung, liver, stomach, spleen, uterus, ovary, intestine, muscle, heart, testis, fat, and brain in mice. The accumulative excretion amounts of 0-24 h, and 0-96 h after administration of 125I-C-1027 were 68.36 and 71.64% in urine, and 2.60 and 3.21% in feces of mice, respectively, and the accumulative excretion amount of 0-24 h was 3.57% in bile in rats. CONCLUSION: Our results reflect the characteristics of the tissue distribution, urinary and fecal excretions of 125I-C-1027 in mice and the biliary excretion of 125I-C-1027 and its metabolites in rats, and indicate that 125I-C-1027 and its metabolites are mainly distributed in kidney, and excreted in urine.展开更多
CEO Howard Kerr of BSI with a delegation Visits SAC and CNIS Mr. Ji Zhengkun, the administrator of Standardization Administration of the People＇s Republic of China （SAC） met Mr. Howard Kerr, the CEO of British Stan...CEO Howard Kerr of BSI with a delegation Visits SAC and CNIS Mr. Ji Zhengkun, the administrator of Standardization Administration of the People＇s Republic of China （SAC） met Mr. Howard Kerr, the CEO of British Standards Institution （BSI） with a delegation of five on Aug. 23, 2010; the two sides highly appraised good cooperation relationship and achievements between SAC and BSI,展开更多
A dual catalytic system, combing visible light photoredox catalysis and iodide catalysis, has been developed for the functionalization of inert C–H bonds. By doing so, radical allylation reactions of N-aryl-tetrahydr...A dual catalytic system, combing visible light photoredox catalysis and iodide catalysis, has been developed for the functionalization of inert C–H bonds. By doing so, radical allylation reactions of N-aryl-tetrahydroisoquinolines(THIQs) were realized under extremely mild conditions, affording a wide variety of allyl-substituted THIQs in up to 78% yields.展开更多
Do agency and stewardship behaviors coexist at firms, or does one dominate the other？ We use data from listed companies in China over the period 2007-2016 to show that powerful chief executive officers （CEOs） simul...Do agency and stewardship behaviors coexist at firms, or does one dominate the other？ We use data from listed companies in China over the period 2007-2016 to show that powerful chief executive officers （CEOs） simultaneously incur self-interested agency costs while acting as stewards to benefit the firm. In balancing the push-and-pull forces of stewardship and agency behaviors, powerful CEOs in Chinese firms ultimately improve short-term and long-term firm performance. Our results have important implications for understanding how CEOs affect firms and how cultural factors can motivate CEOs to work in the interest of the firm.展开更多
Pluripotent stem cells(PSCs) are cells that can differentiate into any type of cells in the body, therefore have valuable promise in regenerative medicine of cell replacement therapies and tissue/organ engineering. PS...Pluripotent stem cells(PSCs) are cells that can differentiate into any type of cells in the body, therefore have valuable promise in regenerative medicine of cell replacement therapies and tissue/organ engineering. PSCs can be derived either from early embryos or directly from somatic cells by epigenetic reprogramming that result in customized cells from patients. Here we summarize the methods of deriving PSCs, the various types of PSCs generated with different status, and their versatile applications in both clinical and embryonic development studies. We also discuss an intriguing potential application of PSCs in constructing tissues/organs in large animals by interspecies chimerism. All these emerging findings are likely to contribute to the breakthroughs in biological research and the prosperous prospects of regenerative medicine.展开更多
基金Supported by PetroChina Company Limited(2020 B-2711)。
文摘End-functionalization of polydiene rubbers can not only improve its compatibility with inorganic fillers,but also enhance the overall mechanical properties.Nevertheless,for traditional neodymium(Nd)diene polymerization systems,it is highly challenging to achieve such end-functionalizations,because most of polydienyl chains are capped withη3-allyl-Nd moiety during the end of polymerization,which shows very poor reactivity with nucleophile compounds.We launched a new diene polymerization strategy calling coordinative chain transfer polymerization(CCTP)[1].In such a system,all the polydienyl chains are capped withη1-allyl-Al moieties,which reveal greater reactivity with cyclic esters and epoxide compounds,providing an effective manner to prepare polydiene-polyester amphiphilic block copolymers.Inspired by such findings,we now show herein how such types of chain-ends react with isot-hiocyanate to demonstrate an efficient in-situ manner to access end-functionalized polydienes by using CCTP.
基金Supported by the National Natural Science Foundation of China(31070443,30970523)the National Science Foundation for Talents Training in Basic Science,China(J1103507)the Project of the Priority Academic Program Development of Jiangsu Higher Education Institutions,China~~
文摘[Objective] To examine the effect of endophytic fungi ALl2 （Gilmaniella sp.） on metabolites distribution in organs of Atractylodes lancea. [Method] Endophytic fungi ALl2 was inoculated on Atraetylodes lancea plantlets in tissue culture, and the distribution of cellulose, hemicellulose, lignin, soluble sugar in leaves and roots of the inoculated group were detected. The weight of leaves and roots were compared. Gas Chromatography was used to analyze the volatile oil components. [Result] Compared with the control group, the average fresh weight and dry weight of leaves and roots of A. lancea which had been symbiosed with ALl2 increased significantly. The content of lignin and soluble sugar increased in the leaves of the inoculated group, and the content of cellulose, hemicellulose, lignin, soluble sugar and volatile oil also increased in roots. [Conclusion] The results indicate that symbiosed with ALl2 is benefit for the development of A. lancea roots and can promote the transfer and accumulation of the medicinal components to the roots.
基金Program for Changjiang Scholars and Innovative Team in University(985-2-063-112).
文摘Aim Syntheses of benzodioxane neolignans. Method The SN2 reaction and Corey-Fuchs reaction was used to synthesize Rodgersinine A, 4-[3-methyl-7-[（E）-1-propenyl-2, 3-dihydro-1, 4-benzodioxin-2-yl]-l, 2-benzenediol （1） and Rodgersinine B, 4- [3-methyl- 7-（1-propynyl）-2, 3-dihydro- 1, 4-benzodioxin-2-yl]-0, 2-benzenediol （2）. Results Total synthesis ofRodgersinine A and B was first completed. Conclusion A useful method for constructing benzodioxane neolignans by the SN2 reaction is achieved.
文摘The spleen could be considered a neglected organ.To date,it has been deemed an ancillary organ in portal hypertension or an organ localization in lymphoproliferative diseases,even though it has had significant attention in infectious diseases for some time.Now,it is thought to be central in regulating the immune system,a metabolic asset and involved in endocrine function with regard to nonalcoholic fatty liver disease.The main mechanisms involved in this complex network will be critically discussed in this article.
文摘A sensory substitution device （SSD） is a technology that translates information for one sensory modality, like vision, into information for use by another, like touch. Though SSDs have been in existence for over four decades, effective training techniques for their use are rarely discussed. In this paper, we compare three training strategies on a particular SSD known as the vOICe. These comparisons were conducted using a minimal but active search and localization task of luminescent discs. These studies show that an interactive training paradigm, which combines the efforts of two trainees at the same time in a tag-like game, is more effective than passive training at a computer console or active training involving search and localization of luminescent discs. This finding supports philosophical views of perception that take interaction with the environment seriously. In particular, we argue that these findings are in support of certain features of the extended mind view as proposed by Andy Clark （2008）. In particular, the study suggests that when environmental conditions are responsive to one＇s behavioral activity, the activity itself is enhanced, as is predicted by the extended mind view.
基金Supported by the National High Technology Research and Development Program of China (863 Program), No. 2003AA2Z347D
文摘AIM: To investigate the tissue distribution, urinary and fecal excretions of 125I-lidamycin (125I-C-1027) in mice and its biliary excretion in rats. METHODS:The total radioactivity assay (RA method) and the radioactivity assay after precipitation with 200 mL/L trichloroacetic add (TCA-RA method) were used to dete-rmine the tissue distribution,and the urinary and fecal excretions of 125I-C-1027 in mice and its biliary excretion in rats. RESULTS:Tissue concentrations reached the peak at the fifth minute after administration of 125I-C-1027 to mice. The highest concentration was in kidney, and the lowest in brain at all test-time points. The organs of the concentrations of 125I-C-1027 from high to low were kidney, lung, liver, stomach, spleen, uterus, ovary, intestine, muscle, heart, testis, fat, and brain in mice. The accumulative excretion amounts of 0-24 h, and 0-96 h after administration of 125I-C-1027 were 68.36 and 71.64% in urine, and 2.60 and 3.21% in feces of mice, respectively, and the accumulative excretion amount of 0-24 h was 3.57% in bile in rats. CONCLUSION: Our results reflect the characteristics of the tissue distribution, urinary and fecal excretions of 125I-C-1027 in mice and the biliary excretion of 125I-C-1027 and its metabolites in rats, and indicate that 125I-C-1027 and its metabolites are mainly distributed in kidney, and excreted in urine.
文摘CEO Howard Kerr of BSI with a delegation Visits SAC and CNIS Mr. Ji Zhengkun, the administrator of Standardization Administration of the People＇s Republic of China （SAC） met Mr. Howard Kerr, the CEO of British Standards Institution （BSI） with a delegation of five on Aug. 23, 2010; the two sides highly appraised good cooperation relationship and achievements between SAC and BSI,
基金supported by the National Natural Science Foundation of China(2123200321202053+2 种基金21572074)the Foundation for the Author of National Excellent Doctoral Dissertation of China(201422)Outstanding Youth Funding in Hubei Province(2015CFA033)
文摘A dual catalytic system, combing visible light photoredox catalysis and iodide catalysis, has been developed for the functionalization of inert C–H bonds. By doing so, radical allylation reactions of N-aryl-tetrahydroisoquinolines(THIQs) were realized under extremely mild conditions, affording a wide variety of allyl-substituted THIQs in up to 78% yields.
基金The authors are grateful for the financial support from the National Natural Science Foundation of China （Grant Nos. 71702084 and 71372179）, and through the research projects of the Humanity and Social Science Youth foundation of the Ministry of Education of China （No. 17YJC630112）.
文摘Do agency and stewardship behaviors coexist at firms, or does one dominate the other？ We use data from listed companies in China over the period 2007-2016 to show that powerful chief executive officers （CEOs） simultaneously incur self-interested agency costs while acting as stewards to benefit the firm. In balancing the push-and-pull forces of stewardship and agency behaviors, powerful CEOs in Chinese firms ultimately improve short-term and long-term firm performance. Our results have important implications for understanding how CEOs affect firms and how cultural factors can motivate CEOs to work in the interest of the firm.
基金supported by the National Natural Science Foundation of China (31471395)
文摘Pluripotent stem cells(PSCs) are cells that can differentiate into any type of cells in the body, therefore have valuable promise in regenerative medicine of cell replacement therapies and tissue/organ engineering. PSCs can be derived either from early embryos or directly from somatic cells by epigenetic reprogramming that result in customized cells from patients. Here we summarize the methods of deriving PSCs, the various types of PSCs generated with different status, and their versatile applications in both clinical and embryonic development studies. We also discuss an intriguing potential application of PSCs in constructing tissues/organs in large animals by interspecies chimerism. All these emerging findings are likely to contribute to the breakthroughs in biological research and the prosperous prospects of regenerative medicine.
