Aim To investigate novel bioactive and structural metabolites from marineorganisms. Methods Column chromatography in association with semi-preparative HPLC were used for theisolation of compounds. 1D and 2D NMR, IR, U...Aim To investigate novel bioactive and structural metabolites from marineorganisms. Methods Column chromatography in association with semi-preparative HPLC were used for theisolation of compounds. 1D and 2D NMR, IR, UV, and MS were employed for structure elucidation.Results From the butanol fraction of the 95% EtOH extract of the starfish Asterias rollestoni, a newcompound N^7 -2'-deoxypseudoxanthosine (1), along with sixteen known compounds, 2'-0-methyl-inosine(2), 2'-deoxyinosine (3), 2'-0-methylguanosine (4), inosine (5); thymine (6), uracil (7), thymidine(8), deoxyuridine (9), 2'-0-methyluridine (10), ( ― )-(1S, 3S)-1-methyl-1, 2, 3,4-terrahydro-β-carboline-3-carboxyl-ic acid (11), ( ― )-(1R, 3S)-1-methyl-1, 2, 3,4-tetrahydro-β-carboline-3-carboxylic acid (12) , ( ― )-(3S)- 1, 2, 3,4-tetrahydro-β-carboline-3-carboxylic acid (13), L-tryptophan (14), L-phenylalanine (15), 3-carboxyindole (16), and p-hydroxybenzoic acid (17) , have been isolated. Conclusion Compound 1 is a newnatural product, and compounds 8, 9 and 10 are isolated from natural sources for the first time, andthe known compounds except 14 and 15 are first reported from starfish Asterias rollestoni.展开更多
To study the changes of the expression of growth-associated protein-43 (GAP-43) and pathology in temporal infarction of rats photochemically induced and the effects of batroxobin. METHODS: Immunohistochemical techniqu...To study the changes of the expression of growth-associated protein-43 (GAP-43) and pathology in temporal infarction of rats photochemically induced and the effects of batroxobin. METHODS: Immunohistochemical technique and hematoxylin-eosin stain was used to show the changes of the expression of GAP-43 and pathology. RESULTS: In infarction group, GAP-43 expression was markedly increased on the infarction and surrounding tissues at 24 h cerebral infarction. The expression reached peak level at 72 h after cerebral infarction and was decreased at 7 d after cerebral infarction. However, in batroxobin-treated group, GAP-43 expression was increased and the pathological changes were much slight as compared with infarction group. CONCLUSION: The expression of GAP-43 increases in infarction of temporal neocortex and batroxobin promotes the expression of GAP-43 and ameliorates the pathological changes in infarction of temporal neocortex.展开更多
Orthogonal test was used to evaluate the effects of synthetic such as temperature （120-140 ℃）, reaction time （4-6） and substrate molar ratio of methyl oleate to sucrose （8：1-12：1） on the percent quantity conv...Orthogonal test was used to evaluate the effects of synthetic such as temperature （120-140 ℃）, reaction time （4-6） and substrate molar ratio of methyl oleate to sucrose （8：1-12：1） on the percent quantity conversion to sucrose polyester. Sucrose polyester was synthesized by a solvent-free one-stage interesterification. The optimum reaction conditions are as follows： methyl oleate/sucrose =10： 1 （mol/mol）; reaction temperature is 140 ℃; reaction time is 5 hours. The product yield reaches 88.15%, and the degree of esterification （DE） is over 7 in the conditions. Thin layer chromatography （TLC）, column chromatography （CC）, High-performance liquid chromatography （HPLC） were used to analyze the product, the results show that the percent of sucrose polyoleate is over 70% in the product. The physicochemical properties of sucrose polyesters were compared with cooking oil. The results show that the qualities of sucrose polyesters are all up to the triglyceride.展开更多
The influence of stabilizing agents and reaction time on the luminescent properties of water-soluble CdTe quantum dots(QDs) was discussed.The thioglycolic acid(TGA)-CdTe ODs were characterized by TEM,XRD and FTIR.It i...The influence of stabilizing agents and reaction time on the luminescent properties of water-soluble CdTe quantum dots(QDs) was discussed.The thioglycolic acid(TGA)-CdTe ODs were characterized by TEM,XRD and FTIR.It is found that larger-size QDs can be synthesized more easily when L-cysteine(Cys) or golutathione(GSH) is chosen as stabilizing agent and TGA is proper to prepare highly luminescent QDs because of the effect between Cd2+ and sulfhydryl group.Furthermore,the absorption wavelength,full width at half maximum(FWHM),stokes shift,photoluminescence(PL) quantum yield and PL stability of TGA-CdTe are strongly dependent on reaction time,in which the absorption wavelength changes against reaction time with an exponential function.The TGA-CdTe QDs prepared at 2 h possess more excellent luminescent properties.展开更多
Task allocation is a key issue of agent cooperation mechanism in Multi-Agent Systems. The important features of an agent system such as the latency of the network infrastructure, dynamic topology, and node heterogenei...Task allocation is a key issue of agent cooperation mechanism in Multi-Agent Systems. The important features of an agent system such as the latency of the network infrastructure, dynamic topology, and node heterogeneity impose new challenges on the task allocation in Multi-Agent environments. Based on the traditional parallel computing task allocation method and Ant Colony Optimization (ACO), a novel task allocation method named Collection Path Ant Colony Optimization (CPACO) is proposed to achieve global optimization and reduce processing time. The existing problems of ACO are analyzed; CPACO overcomes such problems by modifying the heuristic function and the update strategy in the Ant-Cycle Model and establishing a threedimensional path pheromone storage space. The experimental results show that CPACO consumed only 10.3% of the time taken by the Global Search Algorithm and exhibited better performance than the Forward Optimal Heuristic Algorithm.展开更多
Rapid developments in both fundamental science and modern technology that target water-related problems, including the physical nature of our planet and environment, the origin of life, energy production via water spl...Rapid developments in both fundamental science and modern technology that target water-related problems, including the physical nature of our planet and environment, the origin of life, energy production via water splitting, and water purification, all call for a molecular-level understanding of water. This invokes relentless efforts to further our understanding of the basic science of water. Current challenges to achieve a molecular picture of the peculiar properties and behavior of water are discussed herein, with a particular focus on the structure and dynamics of bulk and surface water, the molecular mechanisms of water wetting and splitting, application-oriented research on water decontamination and desalination, and the development of complementary techniques for probing water at the nanoscale.展开更多
Lenin＇s theory of imperialism, which was based on a combination of Marxist theory with active reference to and dialectical critique of the theories of classical imperialism current at the time, provides an empirical ...Lenin＇s theory of imperialism, which was based on a combination of Marxist theory with active reference to and dialectical critique of the theories of classical imperialism current at the time, provides an empirical analysis of the historical logic and laws of motion of capitalism. It realizes the sublation of theory and ideology by means of critical, explanatory and constructive logic, displaying a unique theoretical originality. Lenin＇s theory of imperialism offers a theoretical reflection on the development of capitalism and its historical trends; it is a practical response to the world structural contradictions arising from imperialism, an epochal reflection that vigorously explores and constructs the value claims of a new civilization and provides in-depth Marxist view of world history. The methodology and general principles of Lenin＇s study of imperialism are based on the materialist view of history. They are not out of date, nor are the propositions in his theory of imperialism, based as they are on research into monopoly. At the same time as it declared war on the values, systems and practices of the old world, Lenin＇s theory provided a completely new cognitive method, philosophical attitude and ideal values for the future society. This has become the precious wealth of mankind, wealth that transcends historical time and space.展开更多
This research work based on the development of 6σ capability indices in the Modern Quality Management Practices in the world level companies is briefly introduced. The process performance index （when a process indic...This research work based on the development of 6σ capability indices in the Modern Quality Management Practices in the world level companies is briefly introduced. The process performance index （when a process indicated by control charts is under control） and the percentage of defective products are calculated and compared with kσ. Finally, compared 6σ with 3σ, when process is on nominal （nominal - mean）, the process has 1.5σ shift from nominal.展开更多
文摘Aim To investigate novel bioactive and structural metabolites from marineorganisms. Methods Column chromatography in association with semi-preparative HPLC were used for theisolation of compounds. 1D and 2D NMR, IR, UV, and MS were employed for structure elucidation.Results From the butanol fraction of the 95% EtOH extract of the starfish Asterias rollestoni, a newcompound N^7 -2'-deoxypseudoxanthosine (1), along with sixteen known compounds, 2'-0-methyl-inosine(2), 2'-deoxyinosine (3), 2'-0-methylguanosine (4), inosine (5); thymine (6), uracil (7), thymidine(8), deoxyuridine (9), 2'-0-methyluridine (10), ( ― )-(1S, 3S)-1-methyl-1, 2, 3,4-terrahydro-β-carboline-3-carboxyl-ic acid (11), ( ― )-(1R, 3S)-1-methyl-1, 2, 3,4-tetrahydro-β-carboline-3-carboxylic acid (12) , ( ― )-(3S)- 1, 2, 3,4-tetrahydro-β-carboline-3-carboxylic acid (13), L-tryptophan (14), L-phenylalanine (15), 3-carboxyindole (16), and p-hydroxybenzoic acid (17) , have been isolated. Conclusion Compound 1 is a newnatural product, and compounds 8, 9 and 10 are isolated from natural sources for the first time, andthe known compounds except 14 and 15 are first reported from starfish Asterias rollestoni.
文摘To study the changes of the expression of growth-associated protein-43 (GAP-43) and pathology in temporal infarction of rats photochemically induced and the effects of batroxobin. METHODS: Immunohistochemical technique and hematoxylin-eosin stain was used to show the changes of the expression of GAP-43 and pathology. RESULTS: In infarction group, GAP-43 expression was markedly increased on the infarction and surrounding tissues at 24 h cerebral infarction. The expression reached peak level at 72 h after cerebral infarction and was decreased at 7 d after cerebral infarction. However, in batroxobin-treated group, GAP-43 expression was increased and the pathological changes were much slight as compared with infarction group. CONCLUSION: The expression of GAP-43 increases in infarction of temporal neocortex and batroxobin promotes the expression of GAP-43 and ameliorates the pathological changes in infarction of temporal neocortex.
文摘Orthogonal test was used to evaluate the effects of synthetic such as temperature （120-140 ℃）, reaction time （4-6） and substrate molar ratio of methyl oleate to sucrose （8：1-12：1） on the percent quantity conversion to sucrose polyester. Sucrose polyester was synthesized by a solvent-free one-stage interesterification. The optimum reaction conditions are as follows： methyl oleate/sucrose =10： 1 （mol/mol）; reaction temperature is 140 ℃; reaction time is 5 hours. The product yield reaches 88.15%, and the degree of esterification （DE） is over 7 in the conditions. Thin layer chromatography （TLC）, column chromatography （CC）, High-performance liquid chromatography （HPLC） were used to analyze the product, the results show that the percent of sucrose polyoleate is over 70% in the product. The physicochemical properties of sucrose polyesters were compared with cooking oil. The results show that the qualities of sucrose polyesters are all up to the triglyceride.
基金Projects(10805069,10405034) supported by the National Natural Science Foundation of China
文摘The influence of stabilizing agents and reaction time on the luminescent properties of water-soluble CdTe quantum dots(QDs) was discussed.The thioglycolic acid(TGA)-CdTe ODs were characterized by TEM,XRD and FTIR.It is found that larger-size QDs can be synthesized more easily when L-cysteine(Cys) or golutathione(GSH) is chosen as stabilizing agent and TGA is proper to prepare highly luminescent QDs because of the effect between Cd2+ and sulfhydryl group.Furthermore,the absorption wavelength,full width at half maximum(FWHM),stokes shift,photoluminescence(PL) quantum yield and PL stability of TGA-CdTe are strongly dependent on reaction time,in which the absorption wavelength changes against reaction time with an exponential function.The TGA-CdTe QDs prepared at 2 h possess more excellent luminescent properties.
基金supported by National Natural Science Foundation of China under Grant No.61170117Major National Science and Technology Programs under Grant No.2010ZX07102006+3 种基金National Key Technology R&D Program under Grant No.2012BAH25B02the National 973 Program of China under Grant No.2011CB505402the Guangdong Province University-Industry Cooperation under Grant No.2011A090200008the Scientific Research Foundation, Returned Overseas Chinese Scholars, State Education Ministry
文摘Task allocation is a key issue of agent cooperation mechanism in Multi-Agent Systems. The important features of an agent system such as the latency of the network infrastructure, dynamic topology, and node heterogeneity impose new challenges on the task allocation in Multi-Agent environments. Based on the traditional parallel computing task allocation method and Ant Colony Optimization (ACO), a novel task allocation method named Collection Path Ant Colony Optimization (CPACO) is proposed to achieve global optimization and reduce processing time. The existing problems of ACO are analyzed; CPACO overcomes such problems by modifying the heuristic function and the update strategy in the Ant-Cycle Model and establishing a threedimensional path pheromone storage space. The experimental results show that CPACO consumed only 10.3% of the time taken by the Global Search Algorithm and exhibited better performance than the Forward Optimal Heuristic Algorithm.
基金We thank discussion and help from Chongqin Zhu and Dr. Hui Li, Dr. Z. X. Cao, and Dr. Y. Luo during manuscript preparation. Financial support from NIST, the National Basic Research Program of China （No. 2012CB921403） and the National Natural Science Foundationof China （Nos. 11474328, 11290164, and 11222431） and CAS are gratefully acknowledged.
文摘Rapid developments in both fundamental science and modern technology that target water-related problems, including the physical nature of our planet and environment, the origin of life, energy production via water splitting, and water purification, all call for a molecular-level understanding of water. This invokes relentless efforts to further our understanding of the basic science of water. Current challenges to achieve a molecular picture of the peculiar properties and behavior of water are discussed herein, with a particular focus on the structure and dynamics of bulk and surface water, the molecular mechanisms of water wetting and splitting, application-oriented research on water decontamination and desalination, and the development of complementary techniques for probing water at the nanoscale.
文摘Lenin＇s theory of imperialism, which was based on a combination of Marxist theory with active reference to and dialectical critique of the theories of classical imperialism current at the time, provides an empirical analysis of the historical logic and laws of motion of capitalism. It realizes the sublation of theory and ideology by means of critical, explanatory and constructive logic, displaying a unique theoretical originality. Lenin＇s theory of imperialism offers a theoretical reflection on the development of capitalism and its historical trends; it is a practical response to the world structural contradictions arising from imperialism, an epochal reflection that vigorously explores and constructs the value claims of a new civilization and provides in-depth Marxist view of world history. The methodology and general principles of Lenin＇s study of imperialism are based on the materialist view of history. They are not out of date, nor are the propositions in his theory of imperialism, based as they are on research into monopoly. At the same time as it declared war on the values, systems and practices of the old world, Lenin＇s theory provided a completely new cognitive method, philosophical attitude and ideal values for the future society. This has become the precious wealth of mankind, wealth that transcends historical time and space.
文摘This research work based on the development of 6σ capability indices in the Modern Quality Management Practices in the world level companies is briefly introduced. The process performance index （when a process indicated by control charts is under control） and the percentage of defective products are calculated and compared with kσ. Finally, compared 6σ with 3σ, when process is on nominal （nominal - mean）, the process has 1.5σ shift from nominal.
