Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study)

AIM： TO establish which scolicidal agents are superior and more suitable for regular use. METHODS： Echinococcus granu/osus protoscoleces were obtained from 25 patients with liver hydatid cysts. Various concentrations of albendazole sulfone, albendazole sulfoxide, and albendazole sulfone and albendazole sulfoxide mixed together in concentrations of 50 μg/mL, and H202 in a concentration of 4%, NaCI 20%, and 1.5% cetrimide-0.15% chlorhexidine （10% Savlon-Turkey） were used to determine the scolicidal effects. Albendazole （ABZ） derivatives and other scolicidal agents were applied to a minimum of 100 scoleces for 5 and 10 min. The degree of viability was calculated according to the number of living scolices per field from a total of 100 scolices observed under the microscope. RESULTS： After 5 min, ABZ sulfone was 97.3% effective, ABZ sulfoxide was 98.4% effective, and the combined solution was 98.6% effective. When sulfone, sulfoxide and the combined solutions were compared, the combined solution seemed more effective than sulfone. However, there was no difference when the combined solution was compared with sulfoxide. After 10 min, hypertonic salt water, sulfone, sulfoxide, and the combined solution compared to other solutions looked more effective and this was statistically significant on an advanced level. When sulfone, sulfoxide, and the combined solutions were compared with each other, the combined solution appeared more effective than sulfone. When the combined solution was compared with sulfoxide, there was no difference. CONCLUSION： Despite being active, ABZ metabolites did not provide a marked advantage over 20% hypertonic saline. According to these results, we think creating a newly improved and more active preparation is necessary for hydatid cyst treatment.

A Study of Surfactant-Induced Growth of Ag on Ag (111)

A new growth model is introduced to describe surfactant-induced growth of Ag on Ag （111） with realistic physical parameters. In this model, the A-S exchange mechanism is considered for the first time. Using the Monte Carlo simulations, the influence of exchange mechanism, surface temperature T, the exchange barrier Eεx, and the coverage of surfactant θM on the growth mode and morphology during multilayer film growth of Ag/Ag （111） are studied in detail Both the referenced value of surfactant coverage and the method to obtain perfect layer-by-layer film in surfactantinduced Ag/Ag （111） system are provided. Our simulation results are consistent with many experimental observations for surfactant-induced growth of Ag on Ag （111）.

Do Small Family Firms Outperform Non-family Firms？ A Research Agenda Based on Agency and Stewardship Theories＊

The aim of this study is to examine the effects of family involvement and altruism on agency costs of equity and debt, as well on the performance of small family businesses. To achieve this objective, the authors reviewed the literature on family business. Drawing from agency theory and stewardship theory, the authors also proposed a research model that highlights the links among the variables. In so doing, this paper makes some contributions to the literature in three ways. Firstly, it takes an integrative framework that may help to explain behaviors oriented towards maximizing potential performance within a context in which pro-organizational attitudes co-exist with self-serving motivations. Secondly, it advances the understanding of corporate governance mechanisms in small family businesses, and finally, it deepens the discussion of prior research by advancing a set of propositions based on two theoretical approaches. Thus, the authors believe that a systematic comparison of different contexts provides new insights into small family business governance. The implications and directions for future research are in the last section.

The Conformity Utilization of Ceramic Culture Native Digital Resources Based On the Concept of WEB3.0

In Chinese traditional culture, ceramic culture is a very special cultural system With the advent of the era of network and the particularity of ceramic culture, Make the network native digital resources development and utilization is especially important. The idea of Web3.0 make important ceramic culture network native digital resources ＂reasonable configuration＂, t o be more embody the value of academic research. In this paper, we＇ll discuss the conformity utilization of ceramic culture native digital resources based on the concept of WEB3.0.

Theranostical application of nanomedicine for treating central nervous system disorders

The primary reason for the failure of traditional medicine in treating the disorders of the central nervous system(CNS) is the obstruction to traverse the blood-brain barrier(BBB). Due to the unique physiochemical properties of nanoparticles, they can preferably help deliver drugs passing through the BBB. Researchers have been investigating the capacity of multifunctional nanomaterials as theranostical agents. However, some of the studies have reported controversial results, which might be due to different schematic designs, including size, surface charge, and shape. This review summarizes the applications of nanoparticles to overcome the BBB or contribute to improving the diagnostic and therapeutic effects in CNS diseases.

On Graded Betti Numbers of a Class of Graphs

In this paper, Betti numbers are evaluated for several classes of graphs whose complements are bipartite graphs. Relations are established for the general case, and counting formulae are given in several particular cases, including the union of several mutually disjoint complete graphs.