Lynch syndrome, or hereditary nonpolyposis colorectal cancer (HNPCC), is the most common genetic disorder predisposing to colorectal cancer. As regular colonoscopic surveillance has been shown to reduce the incidence ...Lynch syndrome, or hereditary nonpolyposis colorectal cancer (HNPCC), is the most common genetic disorder predisposing to colorectal cancer. As regular colonoscopic surveillance has been shown to reduce the incidence of colorectal cancer, this strategy is recommended worldwide. Recently, several advances in colonoscopic techniques have improved detection rates of neoplasia in Lynch syndrome. In this nationwide survey, we evaluated current surveillance colonoscopy practices for Lynch syndrome in the Netherlands and the extent to which advanced techniques have been adopted in routine clinical practice.展开更多
The redevelopment of historic cities is often challenged by intricate--and in many cases contradictory--missions. From one side, there is the urge to comprehensively preserve cultural resources. At the same time, oppo...The redevelopment of historic cities is often challenged by intricate--and in many cases contradictory--missions. From one side, there is the urge to comprehensively preserve cultural resources. At the same time, opportunities of economic growth should be made available and needs of contemporary living maintained and nourished. The main aim of this paper is to reconcile probable incompatibilities between such missions through promoting ＂sensitive＂ redevelopment approaches in historic cities. The paper focuses on the city of Luxor, Egypt with its immensely capturing yet quite undermined legend： the Avenue of Sphinxes. In Luxor, the injection of nonintrusive interventions presents itself as a highly potential candidate in protecting and enhancing the experience of the avenue while meeting contemporary needs of living. Adopting less sensitive development approaches can lead the quality of experiencing the whole city to be worsened for the increasing numbers of tourists and locals.展开更多
Despite of all its enigma and revealingness, Israel Epstein＇s （1915-2005） life in communist China remains a vacuum in English-language scholarship on the history of the People＇s Republic of China. This paper inten...Despite of all its enigma and revealingness, Israel Epstein＇s （1915-2005） life in communist China remains a vacuum in English-language scholarship on the history of the People＇s Republic of China. This paper intends to fill this vacuum. It seeks to rediscover Epstein＇s communist experience, with particular focus on his fervent activism in and unapologetic defense of the Cultural Revolution. Through analyzing his experience, this paper exposes the essential allurement of Chinese communism encapsulated in the ideals of revolutionary regeneration and revolutionary virtues. Beyond Epstein＇s communist experience, this paper calls for a deeper and broader pondering on the analogy between communism and religion. Such an illuminating analogy should inspire more intellectual efforts than critical expositions of formalistic vainglory or personality cult.展开更多
Everyone has his heroes, like the college coaches, many of them play a important role in our college life, and they hve a legendary life here at the same time. In America, college student pay attention to NCAA （Natio...Everyone has his heroes, like the college coaches, many of them play a important role in our college life, and they hve a legendary life here at the same time. In America, college student pay attention to NCAA （National Collegiate Athletic Association）, there are many famous coaches in it, such as Nich Saban, Jerry Tarkanian, and more. The authors are very interested in the competitive life of those who are the top five coaches in the world. So the authors concentrate on the winning rate, the contribution rate, and the cycle of the honors to evaluate each coach, by standardizing the metrics, they get the final scores of each metric for basketball; according to the scores, they get the top five coaches in a century. And in this paper, the authors also take the gender and timeline into account.展开更多
The autonomous navigation of an electric vehicle requires the implementation of a number of sensors and actuators intended to inform it about his environment or his position and velocity and deliver necessary inputs. ...The autonomous navigation of an electric vehicle requires the implementation of a number of sensors and actuators intended to inform it about his environment or his position and velocity and deliver necessary inputs. That＇s why it is important to detect and locate sensor and actuator faults as soon as possible to enable the operator to run the vehicle in degraded mode or use the fault tolerant control system if it exists. The main purpose of this paper deals with sensors or actuators faults diagnosis of autonomous vehicle. A diagnosis method using a nonlinear model of the vehicle is developed. Nonlinear state space model of the autonomous electric vehicle is used with the method of nonlinear analytical redundancy to detect and to isolate faults occurred on sensors or actuators. Computer simulations are carried out to verify the effectiveness of the method.展开更多
Genetic algorithms (GAs) employ the evolutionary process of Darwin’s nature selection theory to find the solutions of optimization problems. In this paper, an implementation of genetic algorithm is put forward to sol...Genetic algorithms (GAs) employ the evolutionary process of Darwin’s nature selection theory to find the solutions of optimization problems. In this paper, an implementation of genetic algorithm is put forward to solve a classical transportation problem, namely the Hitchcock’s Transportation Problem (HTP), and the GA is improved to search for all optimal solutions and identify them automatically. The algorithm is coded with C++ and validated by numerical examples. The computational results show that the algorithm is efficient for solving the Hitchcock’s transportation problem.展开更多
This paper describes a novel model known as the shadow obstacle model to generate a realistic comer-tuming behavior in crowd simulation. The motivation for this model comes from the observation that people tend to cho...This paper describes a novel model known as the shadow obstacle model to generate a realistic comer-tuming behavior in crowd simulation. The motivation for this model comes from the observation that people tend to choose a safer route rather than a shorter one when turning a comer. To calculate a safer route, an optimization method is proposed to generate the corner-turning rule that maximizes the viewing range for the agents. By combining psychological and physical forces together, a full crowd simulation framework is established to provide a more realistic crowd simulation. We demonstrate that our model produces a more realistic comer-turning behavior by comparison with real data obtained from the experiments. Finally, we per- form parameter analysis to show the believability of our model through a series of experiments.展开更多
Global illumination is the core part of photo-realistic rendering. The photon mapping algorithm is an effective method for computing global illumination with its obvious advantage of caustic and color bleeding renderi...Global illumination is the core part of photo-realistic rendering. The photon mapping algorithm is an effective method for computing global illumination with its obvious advantage of caustic and color bleeding rendering. It is an active research field that has been developed over the past two decades. The deficiency of precise details and efficient rendering are still the main challenges of photon mapping. This report reviews recent work and classifies it into a set of categories including radiance estimation, photon relaxation, photon tracing, progressive photon mapping, and parallel methods. The goals of our report are giving readers an overall introduction to photon mapping and motivating further research to address the limitations of existing methods.展开更多
Endmember extraction is a key step in the hyperspectral image analysis process. The kernel new simplex growing algorithm （KNSGA）, recently developed as a nonlinear alternative to the simplex growing algorithm （SGA...Endmember extraction is a key step in the hyperspectral image analysis process. The kernel new simplex growing algorithm （KNSGA）, recently developed as a nonlinear alternative to the simplex growing algorithm （SGA）, has proven a promising endmember extraction technique. However, KNSGA still suffers from two issues limiting its application. First, its random initialization leads to inconsistency in final results; second, excessive computation is caused by the iterations of a simplex volume calculation. To solve the first issue, the spatial pixel purity index （SPPI） method is used in this study to extract the first endrnember, eliminating the initialization dependence. A novel approach tackles the second issue by initially using a modified Cholesky fac- torization to decompose the volume matrix into triangular matrices, in order to avoid directly computing the determinant tauto- logically in the simplex volume formula. Theoretical analysis and experiments on both simulated and real spectral data demonstrate that the proposed algorithm significantly reduces computational complexity, and runs faster than the original algorithm.展开更多
We present exact analytical solutions to parity-time(P T) symmetric optical system describing light transport in P T-symmetric optical couplers. We show that light intensity oscillates periodically between two wavegui...We present exact analytical solutions to parity-time(P T) symmetric optical system describing light transport in P T-symmetric optical couplers. We show that light intensity oscillates periodically between two waveguides for unbroken P T-symmetric phase, whereas light always leaves the system from the waveguide experiencing gain when light is initially input at either waveguide experiencing gain or waveguide experiencing loss for broken P T-symmetric phase. These analytical results agree with the recent experimental observation reported by Ru¨ter et al. [Nat. Phys.6(2010) 192]. Besides, we present a scheme for manipulating P T symmetry by applying a periodic modulation. Our results provide an efficient way to control light propagation in periodically modulated P T-symmetric system by tuning the modulation amplitude and frequency.展开更多
Quantum-dot cellular automata （QCA） is an emerging area of research in reversible computing. It can be used to design nanoscale circuits. In nanocommunication, the detection and correction of errors in a received me...Quantum-dot cellular automata （QCA） is an emerging area of research in reversible computing. It can be used to design nanoscale circuits. In nanocommunication, the detection and correction of errors in a received message is a major factor. Besides, device density and power dissipation are the key issues in the nanocommunication architecture. For the first time, QCA-based designs of the reversible low-power odd parity generator and odd parity checker using the Feynman gate have been achieved in this study. Using the proposed parity generator and parity checker circuit, a nanocommunication architecture is pro- posed. The detection of errors in the received message during transmission is also explored. The proposed QCA Feynman gate outshines the existing ones in terms of area, cell count, and delay. The quantum costs of the proposed conventional reversible circuits and their QCA layouts are calculated and compared, which establishes that the proposed QCA circuits have very low quantum cost compared to conventional designs. The energy dissipation by the layouts is estimated, which ensures the possibility ofQCA nano-device serving as an alternative platform for the implementation of reversible circuits. The stability of the proposed circuits under thermal randomness is analyzed, showing the operational efficiency of the circuits. The simulation results of the proposed design are tested with theoretical values, showing the accuracy of the circuits. The proposed circuits can be used to design more complex low-power nanoscale lossless cation architecture such as nano-transmitters and nano-receivers展开更多
A standing wave oscillator(SWO) is a perfect clock source which can be used to produce a high frequency clock signal with a low skew and high reliability. However, it is difficult to tune the SWO in a wide range of fr...A standing wave oscillator(SWO) is a perfect clock source which can be used to produce a high frequency clock signal with a low skew and high reliability. However, it is difficult to tune the SWO in a wide range of frequencies. We introduce a frequency tunable SWO which uses an inversion mode metal-oxide-semiconductor(IMOS) field-effect transistor as a varactor, and give the simulation results of the frequency tuning range and power dissipation. Based on the frequency tunable SWO, a new phase locked loop(PLL) architecture is presented. This PLL can be used not only as a clock source, but also as a clock distribution network to provide high quality clock signals. The PLL achieves an approximately 50% frequency tuning range when designed in Global Foundry 65 nm 1P9 M complementary metal-oxide-semiconductor(CMOS) technology, and can be used directly in a high performance multi-core microprocessor.展开更多
基金supported by Korean Studies Foundation Research through the Ministry of Education of the Republic of Korea and Korean Studies Promotion Service of the Academy of Korean Studies (AKS-2018-KFR-1250001)the phased achievement of the major project of Gansu province's philosophy and social science planning in 2019,"A Phonetic Study of Chinese Dialect in Gansu Section of Jing River Basin"(project number:19ZD003)
文摘Lynch syndrome, or hereditary nonpolyposis colorectal cancer (HNPCC), is the most common genetic disorder predisposing to colorectal cancer. As regular colonoscopic surveillance has been shown to reduce the incidence of colorectal cancer, this strategy is recommended worldwide. Recently, several advances in colonoscopic techniques have improved detection rates of neoplasia in Lynch syndrome. In this nationwide survey, we evaluated current surveillance colonoscopy practices for Lynch syndrome in the Netherlands and the extent to which advanced techniques have been adopted in routine clinical practice.
文摘The redevelopment of historic cities is often challenged by intricate--and in many cases contradictory--missions. From one side, there is the urge to comprehensively preserve cultural resources. At the same time, opportunities of economic growth should be made available and needs of contemporary living maintained and nourished. The main aim of this paper is to reconcile probable incompatibilities between such missions through promoting ＂sensitive＂ redevelopment approaches in historic cities. The paper focuses on the city of Luxor, Egypt with its immensely capturing yet quite undermined legend： the Avenue of Sphinxes. In Luxor, the injection of nonintrusive interventions presents itself as a highly potential candidate in protecting and enhancing the experience of the avenue while meeting contemporary needs of living. Adopting less sensitive development approaches can lead the quality of experiencing the whole city to be worsened for the increasing numbers of tourists and locals.
文摘Despite of all its enigma and revealingness, Israel Epstein＇s （1915-2005） life in communist China remains a vacuum in English-language scholarship on the history of the People＇s Republic of China. This paper intends to fill this vacuum. It seeks to rediscover Epstein＇s communist experience, with particular focus on his fervent activism in and unapologetic defense of the Cultural Revolution. Through analyzing his experience, this paper exposes the essential allurement of Chinese communism encapsulated in the ideals of revolutionary regeneration and revolutionary virtues. Beyond Epstein＇s communist experience, this paper calls for a deeper and broader pondering on the analogy between communism and religion. Such an illuminating analogy should inspire more intellectual efforts than critical expositions of formalistic vainglory or personality cult.
文摘Everyone has his heroes, like the college coaches, many of them play a important role in our college life, and they hve a legendary life here at the same time. In America, college student pay attention to NCAA （National Collegiate Athletic Association）, there are many famous coaches in it, such as Nich Saban, Jerry Tarkanian, and more. The authors are very interested in the competitive life of those who are the top five coaches in the world. So the authors concentrate on the winning rate, the contribution rate, and the cycle of the honors to evaluate each coach, by standardizing the metrics, they get the final scores of each metric for basketball; according to the scores, they get the top five coaches in a century. And in this paper, the authors also take the gender and timeline into account.
文摘The autonomous navigation of an electric vehicle requires the implementation of a number of sensors and actuators intended to inform it about his environment or his position and velocity and deliver necessary inputs. That＇s why it is important to detect and locate sensor and actuator faults as soon as possible to enable the operator to run the vehicle in degraded mode or use the fault tolerant control system if it exists. The main purpose of this paper deals with sensors or actuators faults diagnosis of autonomous vehicle. A diagnosis method using a nonlinear model of the vehicle is developed. Nonlinear state space model of the autonomous electric vehicle is used with the method of nonlinear analytical redundancy to detect and to isolate faults occurred on sensors or actuators. Computer simulations are carried out to verify the effectiveness of the method.
文摘Genetic algorithms (GAs) employ the evolutionary process of Darwin’s nature selection theory to find the solutions of optimization problems. In this paper, an implementation of genetic algorithm is put forward to solve a classical transportation problem, namely the Hitchcock’s Transportation Problem (HTP), and the GA is improved to search for all optimal solutions and identify them automatically. The algorithm is coded with C++ and validated by numerical examples. The computational results show that the algorithm is efficient for solving the Hitchcock’s transportation problem.
基金Project supported by the National Natural Science Foundation of China(Nos.61170318 and 61300133)the Open Research Funding Program of Key Laboratory of Geographic Information Science,China(No.KLGIS2015A05)+1 种基金the Fundamental Research Funds for the Central Universities,China(No.222201514331)the Opening Project of Shanghai Key Laboratory of New Drug Design,China(No.14DZ2272500)
文摘This paper describes a novel model known as the shadow obstacle model to generate a realistic comer-tuming behavior in crowd simulation. The motivation for this model comes from the observation that people tend to choose a safer route rather than a shorter one when turning a comer. To calculate a safer route, an optimization method is proposed to generate the corner-turning rule that maximizes the viewing range for the agents. By combining psychological and physical forces together, a full crowd simulation framework is established to provide a more realistic crowd simulation. We demonstrate that our model produces a more realistic comer-turning behavior by comparison with real data obtained from the experiments. Finally, we per- form parameter analysis to show the believability of our model through a series of experiments.
基金Project supported by the National Natural Science Foundation of China(Nos.61472224 and 61472225)the Young Scholars Program of Shandong University,China(No.2015WLJH41)+2 种基金the Shandong Key Research and Development Program,China(No.2015GGX106006)the Special Funding of Independent Innovation and Transformation of Achievements in Shandong Province of China(No.2014ZZCX08201)the Special Funds of Taishan Scholar Construction Project,China
文摘Global illumination is the core part of photo-realistic rendering. The photon mapping algorithm is an effective method for computing global illumination with its obvious advantage of caustic and color bleeding rendering. It is an active research field that has been developed over the past two decades. The deficiency of precise details and efficient rendering are still the main challenges of photon mapping. This report reviews recent work and classifies it into a set of categories including radiance estimation, photon relaxation, photon tracing, progressive photon mapping, and parallel methods. The goals of our report are giving readers an overall introduction to photon mapping and motivating further research to address the limitations of existing methods.
基金Project supported by the Zhejiang Provincial Natural Science Foundation of China(Nos.LY13F020044 and LZ14F030004)the National Natural Science Foundation of China(No.61571170)
文摘Endmember extraction is a key step in the hyperspectral image analysis process. The kernel new simplex growing algorithm （KNSGA）, recently developed as a nonlinear alternative to the simplex growing algorithm （SGA）, has proven a promising endmember extraction technique. However, KNSGA still suffers from two issues limiting its application. First, its random initialization leads to inconsistency in final results; second, excessive computation is caused by the iterations of a simplex volume calculation. To solve the first issue, the spatial pixel purity index （SPPI） method is used in this study to extract the first endrnember, eliminating the initialization dependence. A novel approach tackles the second issue by initially using a modified Cholesky fac- torization to decompose the volume matrix into triangular matrices, in order to avoid directly computing the determinant tauto- logically in the simplex volume formula. Theoretical analysis and experiments on both simulated and real spectral data demonstrate that the proposed algorithm significantly reduces computational complexity, and runs faster than the original algorithm.
基金Supported by the National Natural Science Foundation of China under Grant No.11465008the Hunan Provincial Natural Science Foundation under Grant Nos.2015JJ4020 and 2015JJ2114the Scientific Research Fund of Hunan Provincial Education Department under Grant No.14A118
文摘We present exact analytical solutions to parity-time(P T) symmetric optical system describing light transport in P T-symmetric optical couplers. We show that light intensity oscillates periodically between two waveguides for unbroken P T-symmetric phase, whereas light always leaves the system from the waveguide experiencing gain when light is initially input at either waveguide experiencing gain or waveguide experiencing loss for broken P T-symmetric phase. These analytical results agree with the recent experimental observation reported by Ru¨ter et al. [Nat. Phys.6(2010) 192]. Besides, we present a scheme for manipulating P T symmetry by applying a periodic modulation. Our results provide an efficient way to control light propagation in periodically modulated P T-symmetric system by tuning the modulation amplitude and frequency.
基金Project supported by the University Grants Commission of India(No.41-631/2012(S.R.))
文摘Quantum-dot cellular automata （QCA） is an emerging area of research in reversible computing. It can be used to design nanoscale circuits. In nanocommunication, the detection and correction of errors in a received message is a major factor. Besides, device density and power dissipation are the key issues in the nanocommunication architecture. For the first time, QCA-based designs of the reversible low-power odd parity generator and odd parity checker using the Feynman gate have been achieved in this study. Using the proposed parity generator and parity checker circuit, a nanocommunication architecture is pro- posed. The detection of errors in the received message during transmission is also explored. The proposed QCA Feynman gate outshines the existing ones in terms of area, cell count, and delay. The quantum costs of the proposed conventional reversible circuits and their QCA layouts are calculated and compared, which establishes that the proposed QCA circuits have very low quantum cost compared to conventional designs. The energy dissipation by the layouts is estimated, which ensures the possibility ofQCA nano-device serving as an alternative platform for the implementation of reversible circuits. The stability of the proposed circuits under thermal randomness is analyzed, showing the operational efficiency of the circuits. The simulation results of the proposed design are tested with theoretical values, showing the accuracy of the circuits. The proposed circuits can be used to design more complex low-power nanoscale lossless cation architecture such as nano-transmitters and nano-receivers
文摘A standing wave oscillator(SWO) is a perfect clock source which can be used to produce a high frequency clock signal with a low skew and high reliability. However, it is difficult to tune the SWO in a wide range of frequencies. We introduce a frequency tunable SWO which uses an inversion mode metal-oxide-semiconductor(IMOS) field-effect transistor as a varactor, and give the simulation results of the frequency tuning range and power dissipation. Based on the frequency tunable SWO, a new phase locked loop(PLL) architecture is presented. This PLL can be used not only as a clock source, but also as a clock distribution network to provide high quality clock signals. The PLL achieves an approximately 50% frequency tuning range when designed in Global Foundry 65 nm 1P9 M complementary metal-oxide-semiconductor(CMOS) technology, and can be used directly in a high performance multi-core microprocessor.
