The temperature characteristics of a silicon microgyroscope are studied, and the temperature compensation method of the silicon microgyroscope is proposed. First, an open-loop circuit is adopted to test the entire mic...The temperature characteristics of a silicon microgyroscope are studied, and the temperature compensation method of the silicon microgyroscope is proposed. First, an open-loop circuit is adopted to test the entire microgyroscope's resonant frequency and quality factor variations over temperature, and the zero bias changing trend over temperature is measured via a closed-loop circuit. Then, in order to alleviate the temperature effects on the performance of the microgyroscope, a kind of temperature compensated method based on the error back propagation(BP)neural network is proposed. By the Matlab simulation, the optimal temperature compensation model based on the BP neural network is well trained after four steps, and the objective error of the microgyroscope's zero bias can achieve 0.001 in full temperature range. By the experiment, the real time operation results of the compensation method demonstrate that the maximum zero bias of the microgyroscope can be decreased from 12.43 to 0.75(°)/s after compensation when the ambient temperature varies from -40 to 80℃, which greatly improves the zero bias stability performance of the microgyroscope.展开更多
Objective To observe the changes of sciatic nerve conduction velocity (SNCV) and interleukin-1α (IL-1α), phospholipase A2 (PLA2) and prostaglandin E2 (PGE2) in neucleus pulposus tissue in experimental rabbit...Objective To observe the changes of sciatic nerve conduction velocity (SNCV) and interleukin-1α (IL-1α), phospholipase A2 (PLA2) and prostaglandin E2 (PGE2) in neucleus pulposus tissue in experimental rabbits with lumbar disc herniation (LDH) ; and discuss the mechanism of LDH treated with bloodletting on Wěizhōng (委中 BL40). Methods 40 normal named control group, LDH model group, BL40 group New Zealand rabbits were randomized into 4 groups, and comparative point group. The experimental LDH model was prepared by the self-made LDH animal pathological modeling device. Bloodletting on BL40 or on comparative point was applied for 7 days. BL-410 physiological signal recorder was used to record SNCV. Enzyme-linked immunosorbent assay (ELISA) and radioimmunology methods were used to determine the contents of IL-1α and PLA2 in neucleus pulposus tissue and PGE2 in serum. Results In BL40 group, SNCV was significantly increased after treatment comparing with that before treatment (P〈0. 01 ), and the difference in SNCV value before and after treatment was significantly bigger than that in model group and comparative point group (P〈0.05). Bloodletting on BL40 reduced the contents of IL-1α and PLA2 in neucleus pulposus tissue and serum PGE2 in LDH rabbits, which indicated significant difference or very significant results in the comparison with model and comparative point groups (P〈0.01 or 0. 05). Conclusion Bloodletting speeded up rapidly SNCV and reduced the contents of inflammatory factors, i.e. IL-1α, PLA2 and serum PGE2 in LDH rabbits, which indicated that alleviation of local inflammatory reaction is probably one of the mechanisms on LDH treated by bloodletting on BL40.展开更多
Objective To observe clinical therapeutic effects of warm needling and moxibustion on diabetic peripheral neuropathy (DPN) and their influence on nerve conduction velocity. Methods Fifty two cases were randomly divi...Objective To observe clinical therapeutic effects of warm needling and moxibustion on diabetic peripheral neuropathy (DPN) and their influence on nerve conduction velocity. Methods Fifty two cases were randomly divided into a treatment group (n =26) and a control group (n =26). In addition to basic treatment for lowering blood sugar in both groups, Pǐshū (BL 20), Shènshū (BL 23), Huántiào (GB 30), Zùsānlǐ (ST 36), Yánglíngquán (GB 34), Sānyīnjiāo (SP 6), Tàixī (KI 3), Qǔchí (LI 11), Wàiguān (TE 5) and Hégǔ (LI 4) were selected for warm needling and moxibustion in the treatment group. Methycobal was intramuscularly injected in the control group. Clinical symptoms and conduction velocities of the tibial nerve and common peroneal nerve were compared before and after treatment. Results Warm needling and moxibustion could alleviate such clinical symptoms as numbness of limbs, pain and hypoesthesia, and obviously improve the conduction velocities of both tibial and common peroneal nerves. Conclusion Warm needling and moxibustion exhibit good therapeutic effects on diabetic peripheral neuropathy.展开更多
Physiological parameters of people and enact assessment standard of indoor thermal environment that are appropriate to our national conditions were explored from the perspective of physiology. From December 2005 to Ja...Physiological parameters of people and enact assessment standard of indoor thermal environment that are appropriate to our national conditions were explored from the perspective of physiology. From December 2005 to January 2006, nerve conduction velocities and skin temperatures of 20 healthy students were tested with questionnaire investigation. The results show that the nerve conduction velocities as well as skin temperatures present an obvious decline trend in a continuous draught, and that the nerve conduction velocities and skin temperatures have a definite linear relationship. Draught velocity is an important factor in winter that affects body comfort, and the subjects are sensitive to air velocity.展开更多
A novel speed sensor-less direct torque control induction motor drive system for the mining locomotive haulage is presented in the paper. Rotor speed identification is based on the model reference adaptive control the...A novel speed sensor-less direct torque control induction motor drive system for the mining locomotive haulage is presented in the paper. Rotor speed identification is based on the model reference adaptive control theory with neural network using back propagation algorithm. The system is implemented using a real-time TMS320F240 digital signal processor. The simulation study and experiment results indicate that the suggested system has good performance.展开更多
Objective To investigate the mechanisms of acupuncture in accelerating regeneration of injured sciatic nerve, the effect of electroacupuncture (EA) at "Huantiao (环跳 GB 30)" and "Zusanli (足三里 ST 36)" on ...Objective To investigate the mechanisms of acupuncture in accelerating regeneration of injured sciatic nerve, the effect of electroacupuncture (EA) at "Huantiao (环跳 GB 30)" and "Zusanli (足三里 ST 36)" on conduction velocity and mRNA expression of receptors of advanced glycation end products (RAGE) of the sciatic nerve were observed in experimental diabetic rats. Methods Streptozotocin was injected into the left abdomen in 30 male rats to establish diabetes mellitus (DM) models with hyperglycemia (〉16.7 mmol/L). Thirty rats with DM were divided into a diabetes model group (group DM), a Methycobal group (group MET) and an EA group (group EA). Another 8 rats comparable in body weight and age were used as a normal control group (group NC). General situation and blood sugar levels of all the rats were recorded, and the conduction velocities of the sciatic nerves were measured. RAGE mRNA expression of the sciatic nerve was detected by means of reverse transcription polymerase chain reaction(RT-PCR)16 weeks after treatment. Results After 16 weeks, the conduction velocities of the sciatic nerves were lowered in group DM, compared with those in group NC, indicating lesion of peripheral nerves. Compared with group DM, the conduction velocities of the sciatic nerves were significantly elevated in both group EA and group MET (P〈0.01 ), and there was a significant difference between the two groups, showing superiority of EA to Methycobal (P〈0.01). The RAGE mRNA levels of the sciatic nerves in group DM were significantly higher than those in group NC (P〈0.01). The RAGE mRNA levels of the sciatic nerves in both group EA and group MET were remarkably lowered than those in group DM (P〈0.01), and the decrease in group EA was more obviously than that in group MET (P〈0.01). Conclusion EA may exert its therapeutic effects on diabetic perineuropathy (DPN) by way of regulating abnormal expression of RAGE mRNA in the sciatic nerve and alleviating its injury caused by advanced glycation end products (AGEs) accumulation and diminishing oxidative stress to enhance its conduction velocity.展开更多
A discussion is given on the convergence of the on-line gradient methods for two-layer feedforward neural networks in general cases. The theories are applied to some usual activation functions and energy functions.
The present study presents a peripheral nerve injury animal model for evaluation of an implantable electrical stimulator we designed.The evaluation was confirmed by ethological,electrophysiological and histologic stud...The present study presents a peripheral nerve injury animal model for evaluation of an implantable electrical stimulator we designed.The evaluation was confirmed by ethological,electrophysiological and histologic study.Twenty New Zealand rabbits were used.The left sciatic nerve was crushed with a micro-vessel clamp in all rabbits,and the stimulators were implanted in ten rabbits.The other ten rabbits were in a control group.As compared with the implantation group,3 and 6 weeks after operation,the histology showed the typical pathologic atrophy by hematoxylin-eosin(HE) ,the motor nerve conduction velocity(MCV) was found significantly slowed and the axon of crushed nerve at distal portion exhibited breakdown in the control group.These results reveal that the implantable electrical stimulator was effective and was suitable for implantation in an animal model.展开更多
Objective: To explore the effect of electro-acupuncture and musk injection on recovery of injured sciatic nerve function in rats, so as to provide the experimental evidences for the promotion of peripheral nerve rege...Objective: To explore the effect of electro-acupuncture and musk injection on recovery of injured sciatic nerve function in rats, so as to provide the experimental evidences for the promotion of peripheral nerve regeneration by electro-acupuncture and musk injection. Methods: Following establishing rat model of sciatic nerve injury by operation, the rats were randomly divided into electro-acupuncture group, musk injection group, electro-acupuncture plus musk injection group and model group, then sciatic functional index (SFI) and motor nerve conduction velocity (MNCV) were measured after 4 weeks of treatment, 8 weeks of treatment and 12 weeks of treatment respectively to evaluate recovery of nerve function. Results: SFI and MNCV in electro-acupuncture group, musk injection group and electro-acupuncture plus musk injection group were improved more obviously than that in model group, with significant differences(P〈0.01, P〈0.05). Conclusions: Both electro-acupuncture and musk injection could promote recovery of injured nerve function, and they had a certain synergetic effect and might be the effective methods in promoting recovery of injured peripheral nerve function.展开更多
Primary blast-induced traumatic brain injury (bTBI) has been observed at the boundary of brain tissue and cerebrospinal fluid (CSF). Such injury can hardly be explained by using the theory of compressive wave prop...Primary blast-induced traumatic brain injury (bTBI) has been observed at the boundary of brain tissue and cerebrospinal fluid (CSF). Such injury can hardly be explained by using the theory of compressive wave propagation, since both the solid and fluid materials have similar compressibility and thus the intracranial pressure (ICP) has a continuous distribution across the boundary. Since they have completely different shear properties, it is hypothesized the injury at the interface is caused by shear wave. In the present study, a preliminary combined numerical and theoretical analysis was conducted based on the theory of shear wave propagation]reflection. Simulation results show that higher lateral acceleration of brain tissue particles is concentrated in the boundary region. Based on this finding, a new biomechanical vector, termed as strain gradient, was suggested for primary bTBI. The subsequent simple theoretical analysis reveals that this parameter is proportional to the value of lateral acceleration. At the boundary of lateral ventricles, high spatial strain gradient implies that the brain tissue in this area (where neuron cells may be contained) undergo significantly different strains and large velocity discontinuity, which may result in mechanical damage of the neuron cells.展开更多
基金The National High Technology Research and Development Program of China (863 Program)(No.2002AA812038)the NationalNatural Science Foundation of China (No.60974116)
文摘The temperature characteristics of a silicon microgyroscope are studied, and the temperature compensation method of the silicon microgyroscope is proposed. First, an open-loop circuit is adopted to test the entire microgyroscope's resonant frequency and quality factor variations over temperature, and the zero bias changing trend over temperature is measured via a closed-loop circuit. Then, in order to alleviate the temperature effects on the performance of the microgyroscope, a kind of temperature compensated method based on the error back propagation(BP)neural network is proposed. By the Matlab simulation, the optimal temperature compensation model based on the BP neural network is well trained after four steps, and the objective error of the microgyroscope's zero bias can achieve 0.001 in full temperature range. By the experiment, the real time operation results of the compensation method demonstrate that the maximum zero bias of the microgyroscope can be decreased from 12.43 to 0.75(°)/s after compensation when the ambient temperature varies from -40 to 80℃, which greatly improves the zero bias stability performance of the microgyroscope.
文摘Objective To observe the changes of sciatic nerve conduction velocity (SNCV) and interleukin-1α (IL-1α), phospholipase A2 (PLA2) and prostaglandin E2 (PGE2) in neucleus pulposus tissue in experimental rabbits with lumbar disc herniation (LDH) ; and discuss the mechanism of LDH treated with bloodletting on Wěizhōng (委中 BL40). Methods 40 normal named control group, LDH model group, BL40 group New Zealand rabbits were randomized into 4 groups, and comparative point group. The experimental LDH model was prepared by the self-made LDH animal pathological modeling device. Bloodletting on BL40 or on comparative point was applied for 7 days. BL-410 physiological signal recorder was used to record SNCV. Enzyme-linked immunosorbent assay (ELISA) and radioimmunology methods were used to determine the contents of IL-1α and PLA2 in neucleus pulposus tissue and PGE2 in serum. Results In BL40 group, SNCV was significantly increased after treatment comparing with that before treatment (P〈0. 01 ), and the difference in SNCV value before and after treatment was significantly bigger than that in model group and comparative point group (P〈0.05). Bloodletting on BL40 reduced the contents of IL-1α and PLA2 in neucleus pulposus tissue and serum PGE2 in LDH rabbits, which indicated significant difference or very significant results in the comparison with model and comparative point groups (P〈0.01 or 0. 05). Conclusion Bloodletting speeded up rapidly SNCV and reduced the contents of inflammatory factors, i.e. IL-1α, PLA2 and serum PGE2 in LDH rabbits, which indicated that alleviation of local inflammatory reaction is probably one of the mechanisms on LDH treated by bloodletting on BL40.
文摘Objective To observe clinical therapeutic effects of warm needling and moxibustion on diabetic peripheral neuropathy (DPN) and their influence on nerve conduction velocity. Methods Fifty two cases were randomly divided into a treatment group (n =26) and a control group (n =26). In addition to basic treatment for lowering blood sugar in both groups, Pǐshū (BL 20), Shènshū (BL 23), Huántiào (GB 30), Zùsānlǐ (ST 36), Yánglíngquán (GB 34), Sānyīnjiāo (SP 6), Tàixī (KI 3), Qǔchí (LI 11), Wàiguān (TE 5) and Hégǔ (LI 4) were selected for warm needling and moxibustion in the treatment group. Methycobal was intramuscularly injected in the control group. Clinical symptoms and conduction velocities of the tibial nerve and common peroneal nerve were compared before and after treatment. Results Warm needling and moxibustion could alleviate such clinical symptoms as numbness of limbs, pain and hypoesthesia, and obviously improve the conduction velocities of both tibial and common peroneal nerves. Conclusion Warm needling and moxibustion exhibit good therapeutic effects on diabetic peripheral neuropathy.
基金Project(CSTC 2004AA7008) supported by the State I mportant Project of the Science and Technology
文摘Physiological parameters of people and enact assessment standard of indoor thermal environment that are appropriate to our national conditions were explored from the perspective of physiology. From December 2005 to January 2006, nerve conduction velocities and skin temperatures of 20 healthy students were tested with questionnaire investigation. The results show that the nerve conduction velocities as well as skin temperatures present an obvious decline trend in a continuous draught, and that the nerve conduction velocities and skin temperatures have a definite linear relationship. Draught velocity is an important factor in winter that affects body comfort, and the subjects are sensitive to air velocity.
文摘A novel speed sensor-less direct torque control induction motor drive system for the mining locomotive haulage is presented in the paper. Rotor speed identification is based on the model reference adaptive control theory with neural network using back propagation algorithm. The system is implemented using a real-time TMS320F240 digital signal processor. The simulation study and experiment results indicate that the suggested system has good performance.
文摘Objective To investigate the mechanisms of acupuncture in accelerating regeneration of injured sciatic nerve, the effect of electroacupuncture (EA) at "Huantiao (环跳 GB 30)" and "Zusanli (足三里 ST 36)" on conduction velocity and mRNA expression of receptors of advanced glycation end products (RAGE) of the sciatic nerve were observed in experimental diabetic rats. Methods Streptozotocin was injected into the left abdomen in 30 male rats to establish diabetes mellitus (DM) models with hyperglycemia (〉16.7 mmol/L). Thirty rats with DM were divided into a diabetes model group (group DM), a Methycobal group (group MET) and an EA group (group EA). Another 8 rats comparable in body weight and age were used as a normal control group (group NC). General situation and blood sugar levels of all the rats were recorded, and the conduction velocities of the sciatic nerves were measured. RAGE mRNA expression of the sciatic nerve was detected by means of reverse transcription polymerase chain reaction(RT-PCR)16 weeks after treatment. Results After 16 weeks, the conduction velocities of the sciatic nerves were lowered in group DM, compared with those in group NC, indicating lesion of peripheral nerves. Compared with group DM, the conduction velocities of the sciatic nerves were significantly elevated in both group EA and group MET (P〈0.01 ), and there was a significant difference between the two groups, showing superiority of EA to Methycobal (P〈0.01). The RAGE mRNA levels of the sciatic nerves in group DM were significantly higher than those in group NC (P〈0.01). The RAGE mRNA levels of the sciatic nerves in both group EA and group MET were remarkably lowered than those in group DM (P〈0.01), and the decrease in group EA was more obviously than that in group MET (P〈0.01). Conclusion EA may exert its therapeutic effects on diabetic perineuropathy (DPN) by way of regulating abnormal expression of RAGE mRNA in the sciatic nerve and alleviating its injury caused by advanced glycation end products (AGEs) accumulation and diminishing oxidative stress to enhance its conduction velocity.
基金Supported by the Natural Science Foundation of China
文摘A discussion is given on the convergence of the on-line gradient methods for two-layer feedforward neural networks in general cases. The theories are applied to some usual activation functions and energy functions.
基金the Shanghai-Philips Research & Development Fund of China (No.06SP07001)Shanghai Rising-Star Program (No.08QH14015)
文摘The present study presents a peripheral nerve injury animal model for evaluation of an implantable electrical stimulator we designed.The evaluation was confirmed by ethological,electrophysiological and histologic study.Twenty New Zealand rabbits were used.The left sciatic nerve was crushed with a micro-vessel clamp in all rabbits,and the stimulators were implanted in ten rabbits.The other ten rabbits were in a control group.As compared with the implantation group,3 and 6 weeks after operation,the histology showed the typical pathologic atrophy by hematoxylin-eosin(HE) ,the motor nerve conduction velocity(MCV) was found significantly slowed and the axon of crushed nerve at distal portion exhibited breakdown in the control group.These results reveal that the implantable electrical stimulator was effective and was suitable for implantation in an animal model.
文摘Objective: To explore the effect of electro-acupuncture and musk injection on recovery of injured sciatic nerve function in rats, so as to provide the experimental evidences for the promotion of peripheral nerve regeneration by electro-acupuncture and musk injection. Methods: Following establishing rat model of sciatic nerve injury by operation, the rats were randomly divided into electro-acupuncture group, musk injection group, electro-acupuncture plus musk injection group and model group, then sciatic functional index (SFI) and motor nerve conduction velocity (MNCV) were measured after 4 weeks of treatment, 8 weeks of treatment and 12 weeks of treatment respectively to evaluate recovery of nerve function. Results: SFI and MNCV in electro-acupuncture group, musk injection group and electro-acupuncture plus musk injection group were improved more obviously than that in model group, with significant differences(P〈0.01, P〈0.05). Conclusions: Both electro-acupuncture and musk injection could promote recovery of injured nerve function, and they had a certain synergetic effect and might be the effective methods in promoting recovery of injured peripheral nerve function.
文摘Primary blast-induced traumatic brain injury (bTBI) has been observed at the boundary of brain tissue and cerebrospinal fluid (CSF). Such injury can hardly be explained by using the theory of compressive wave propagation, since both the solid and fluid materials have similar compressibility and thus the intracranial pressure (ICP) has a continuous distribution across the boundary. Since they have completely different shear properties, it is hypothesized the injury at the interface is caused by shear wave. In the present study, a preliminary combined numerical and theoretical analysis was conducted based on the theory of shear wave propagation]reflection. Simulation results show that higher lateral acceleration of brain tissue particles is concentrated in the boundary region. Based on this finding, a new biomechanical vector, termed as strain gradient, was suggested for primary bTBI. The subsequent simple theoretical analysis reveals that this parameter is proportional to the value of lateral acceleration. At the boundary of lateral ventricles, high spatial strain gradient implies that the brain tissue in this area (where neuron cells may be contained) undergo significantly different strains and large velocity discontinuity, which may result in mechanical damage of the neuron cells.