Outstanding progress regarding the pathophysiology of Crohn's disease (CD) has led to the development of innovative therapeutic concepts. Numerous controlled trials have been performed in CD. This review concentra...Outstanding progress regarding the pathophysiology of Crohn's disease (CD) has led to the development of innovative therapeutic concepts. Numerous controlled trials have been performed in CD. This review concentrates on the results of randomized,placebo-controlled trials,and meta-analyses when available,that provide the highest degree of evidence. Current guidelines on the management of CD recommend a step-up approach to treatment involving the addition of more powerful therapies as the severity of disease and refractoriness to therapy increase. The advent of biological drugs has opened new therapeutic horizons for treating CD,modifying the treatment goals. However,the large majority of patients with CD will be managed through conventional therapy,even if they are a prelude to biological therapy.展开更多
Deregulation of power system industry is a very large complex exercise based on respective national energy strategies and policies. A lot of matters and knowledge need to be studied before the idea of deregulation can...Deregulation of power system industry is a very large complex exercise based on respective national energy strategies and policies. A lot of matters and knowledge need to be studied before the idea of deregulation can be implemented. Theoretically, it is said that deregulation can make a large impact to increase efficiency and encourage the competitiveness among related parties. However, to implement the concept of deregulation to electric power supply is very tough challenge. In deregulation environment, regardless of market structure, to know the transmission usage allocation is vital and very a complex problem. Thus, a lot of algorithms have been proposed to overcome it. This paper intends to solve the transmission usage allocation problem using optimization approach. The optimization tool that will be utilized is Genetic Algorithm (GA). GA is probabilistic search technique that has its roots in the principle of genetics and strives for survival. In addition, GA is very robust. Since the nonlinear nature of power flow, it is expected that GA can give optimize results that equitable and acceptable. In this paper, 4-bus and Klos-Kerner 11-bus systems are used for analysis studies. Comparison with other method is also given in this paper.展开更多
An approach was proposed for optimizing beamforming that was based on Support Vector Regression (SVR). After studying the mathematical principal of the SVR algorithm and its primal cost function, the modified cost fun...An approach was proposed for optimizing beamforming that was based on Support Vector Regression (SVR). After studying the mathematical principal of the SVR algorithm and its primal cost function, the modified cost function was first applied to uniform array beamforming, and then the corresponding parameters of the beamforming were optimized. The framework of SVR uniform array beamforming was then established. Simulation results show that SVR beamforming can not only approximate the performance of conventional beamforming in the area without noise and with small data sets, but also improve the generalization ability and reduce the computation burden. Also, the side lobe level of both linear and circular arrays by the SVR algorithm is improved sharply through comparison with the conventional one. SVR beamforming is superior to the conventional method in both linear and circular arrays, under single source or double non-coherent sources.展开更多
文摘Outstanding progress regarding the pathophysiology of Crohn's disease (CD) has led to the development of innovative therapeutic concepts. Numerous controlled trials have been performed in CD. This review concentrates on the results of randomized,placebo-controlled trials,and meta-analyses when available,that provide the highest degree of evidence. Current guidelines on the management of CD recommend a step-up approach to treatment involving the addition of more powerful therapies as the severity of disease and refractoriness to therapy increase. The advent of biological drugs has opened new therapeutic horizons for treating CD,modifying the treatment goals. However,the large majority of patients with CD will be managed through conventional therapy,even if they are a prelude to biological therapy.
文摘Deregulation of power system industry is a very large complex exercise based on respective national energy strategies and policies. A lot of matters and knowledge need to be studied before the idea of deregulation can be implemented. Theoretically, it is said that deregulation can make a large impact to increase efficiency and encourage the competitiveness among related parties. However, to implement the concept of deregulation to electric power supply is very tough challenge. In deregulation environment, regardless of market structure, to know the transmission usage allocation is vital and very a complex problem. Thus, a lot of algorithms have been proposed to overcome it. This paper intends to solve the transmission usage allocation problem using optimization approach. The optimization tool that will be utilized is Genetic Algorithm (GA). GA is probabilistic search technique that has its roots in the principle of genetics and strives for survival. In addition, GA is very robust. Since the nonlinear nature of power flow, it is expected that GA can give optimize results that equitable and acceptable. In this paper, 4-bus and Klos-Kerner 11-bus systems are used for analysis studies. Comparison with other method is also given in this paper.
基金the Foundation of Returned Scholar of Shaanxi Province(SLZ2008006)
文摘An approach was proposed for optimizing beamforming that was based on Support Vector Regression (SVR). After studying the mathematical principal of the SVR algorithm and its primal cost function, the modified cost function was first applied to uniform array beamforming, and then the corresponding parameters of the beamforming were optimized. The framework of SVR uniform array beamforming was then established. Simulation results show that SVR beamforming can not only approximate the performance of conventional beamforming in the area without noise and with small data sets, but also improve the generalization ability and reduce the computation burden. Also, the side lobe level of both linear and circular arrays by the SVR algorithm is improved sharply through comparison with the conventional one. SVR beamforming is superior to the conventional method in both linear and circular arrays, under single source or double non-coherent sources.