刺激空间特征和反应位置对线索效应模式的影响

以具有不同空间特征的十字号为实验材料,采用反应线索范式,旨在探讨刺激空间特征和反应位置对线索效应模式的影响。结果表明:①左右特征突显可以获得最优的反应准备绩效,而内外特征突显增强则导致最差的反应准备绩效;②不同线索效应间的差别主要出现在中间两个反应位置上,尤以突显特征增强时明显。结论:左右特征突显是线索反应任务中较为理想的空间刺激安排方式;与外侧两个反应位置相比,线索对于中间两个反应位置的提示作用更大。

例谈生物膜上反应的准确位置

高中生物学教材中涉及到许多反应的场所与生物膜有关,可是对一些反应发生的准确位置往往没有清楚交代,本文对光合作用光反应、细胞呼吸第三阶段反应、激素与受体结合的准确位置进行了明确阐述。

视觉导引机器人定性定位与导航

在总结己有定性导航工作的基础上,系统地讨论了定性定位的两种方法——顺序区域和有向区域定位,以及各自的性质和相互关系,并给出了实验结果。

S－R相容性：概念、分类、理论假设及应用

Ｓ－Ｒ相容性：概念、分类、理论假设及应用刘艳芳（中国科学院心理研究所）１引言刺激一反应相容性（ｓｔｉｍｕｌｕｓ－ｒｅｓｐｏｎｓｅｃｏｍｐａｔｉｂｉｌｉｔｙ）的研究源于第二次世界大战美国空军对显示屏的研究，而真正使Ｓ－Ｒ相容性成为心理学研究的主题之一的...

Optimization of coproduction of ethyl acetate and n-butyl acetate by reactive distillation

Based on a previous investigation,a simulation model was used for optimization of coproduction of ethyl acetate and n-butyl acetate by reactive distillation.An experimental setup was established to verify the simulated results.The effects of various operating variables,such as ethanol feed location,acetic acid feed location,feed stage of reaction mixture of acetic acid and n-butanol,reflux ratio of ethyl acetate reactive distillation column,and distillate to feed ratio of n-butyl acetate column,on the ethanol/n-butanol conversions,ethyl acetate/n-butyl acetate purity,and energy consumption were investigated.The optimal results in the simulation study are as follows:ethanol feed location,15th stage;acetic acid feed location,eighth stage;feed location of reaction mixture of acetic acid and n-butanol,eighth stage;reflux ratio of ethyl acetate reactive distillation column,2.0;and distillate to feed ratio of n-butyl acetate,0.6.

Experimental study by online measurement of the precipitation of nickel hydroxide: Effects of operating conditions

The objective of this work is using the online measurement method to study the process of precipitation of nickel hydroxide in a single-feed semi-batch stirred reactor with an internal diameter ofD = 240mm. The effects of impeller speed, impeller type, impeller diameter and feed location on the mean particle size d43 and particle size distribution （PSD） were investigated, d43 and PSD were measured online using a Malvern Insitec Liquid Pro- cess Sizer every 20 s. It was found that d43 varied between 13 kwh and 26 lain under different operating conditions, and it decreased with increasing impeller diameter. When feeding at the off-bottom distance of D/2 under lower impeller speeds, d43 was significantly smaller than that at D/3. PSDs were slightly influenced by operating conditions.

Positional effect of mutations in 5'UTR of hepatitis C virus 4a on patients' response to therapy

AIM： To investigate the effects of mutations in domain Ⅲ of the hepatitis C virus （HCV） internal ribosome entry sequences （IRES） on the response of chronic HCV genotype 4a patients to interferon therapy.METHODS： HCV RNA was extracted from 19 chronic HCV 4a patients receiving interferon/ribavirin therapy who showed dramatic differences in their response to combination therapy after initial viral clearance. IRES domain Ⅲ was cloned and 15 clones for each patient were sequenced. The obtained sequences were aligned with genotype 4a prototype using the ClustaIW program and mutations scored. Prediction of stem-loop secondary structure and thermodynamic stability of the major quasispecies in each patient was performed using the MFOLD 3.2 program with Turner energies and selected constraints on base pairing.RESULTS： Analysis of RNA secondary structure revealed that insertions in domain Ⅲ altered WatsonCrick base pairing of stems and reduced molecular stability of RNA, which may ultimately reduce binding affinity to ribosomal proteins. Insertion mutations in domain - were statistically more prevalent in sustained viral response patients （SVR, n = 14） as compared to breakthrough （BT, n = 5） patients.CONCLUSION： The influence of mutations within domain Ⅲ on the response of HCV patients to combination therapy depends primarily on the position, but not the frequency, of these mutations within IRES domain Ⅲ.

Development of Design Response Spectra Based on Various Attenuation Relationships at Specific Location

Peninsular Malaysia is located and lies in a low seismic region. Although Malaysia is not located in the active fault seismic area, it is closed to the Sumatran active seismic zones. Tall building are fIequently felt the tremor generated fTom Sumatran subduction and fault zones especially in the west cost of Peninsular Malaysia such as Johor Bahru, Kuala Lumpur and Penang. Existing design response spectra was developed based on attenuation relationship for each subduction and fault zone. In this study, the design response spectra were developed based on various attenuation relationships for selected location in Kuala Lumpur area, namely, Mutiara Damansara, Bandar Petaling Jaya and Bandar Puteri Puchong. The development of design response spectra based on various attenuation relationships is more reliable in selecting the appropriate attenuation relationship for the study area. Seven attenuations have been chosen and results show that Megawati et al. are the most appropriate attenuation relation for fault zone, where the predicted PGA （peak ground acceleration） is 0.0187 g which is the proposed PGA value for this study area. This study also found that most of soil in the study area can be categorized into SD （stiff soil） according to site classification in the NEHRP 2000 Provision/UBC 97. Bandar petaling Jaya was found to be highest AF （amplification factor） of 3.74 for stiff soil and Mutiara Damansara with AF of 2.67 for very dense soil or soft rock. The proposed design response spectra for each location were developed based on UBC 1997 （Uniform Building Code 1997）. The peak RSA （response spectrum acceleration） of 0.30 g for soil type SD for Bandar Petaling Jaya is the maximum level of acceleration on the soil surface with a period range of 0.10 to 0.52 seconds. All these values can be used for the seismic safety evaluation of existing structures and as a guideline in designing new structures to resist future earthquake, within the study area.

Interpreting the dynamic effect of internal heat integration on reactive distillation columns

In this work,the impact of internal heat integration upon process dynamics and controllability by superposing reactive section onto stripping section,relocating feed locations,and redistributing catalyst within the reactive section is explored based on a hypothetical ideal reactive distillation system containing an exothermic reaction:A + BC + D.Steady state operation analysis and closed-loop controllability evaluation are carried out by comparing the process designs with and without the consideration of internal heat integration.For superposing reactive section onto stripping section,favorable effect is aroused due to its low sensitivities to the changes in operating condition.For ascending the lower feed stage,somewhat detrimental effect occurs because of the accompanied adverse internal heat integration and strong sensitivity to the changes in operating condition.For descending the upper feed stage,serious detrimental effect happens because of the introduced adverse internal heat integration and strong sensitivity to the changes in operating condition.For redistributing catalyst in the reactive section,fairly small negative influence is aroused by the sensitivity to the changes in operating condition.When reinforcing internal heat integration with a combinatorial use of these three strategies,the decent of the upper feed stage should be avoided in process development.Although the conclusions are derived based on the hypothetical ideal reactive distillation column studied,they are considered to be of general significance to the design and operation of other reactive distillation columns.

Insufficient thermalization effects on determining fission-track ages

Fission-Track Dating (FTD) has been developed as a useful technique for geological studies. Parent elements are measured by counting 235 U tracks induced by thermal neutrons. If insufficient thermalization occurs, fission of 238 U and 232 Th will be induced, and further measurement error will be introduced. Therefore, whether the neutrons are well thermalized or not will affect the FTD results. Due to requirement of safe operation, the 101 reactor was terminated in 2007. By using the 492 reactor as the new thermal neutron reactor, our present paper will attempt to study the feasibility and the potential influence on FTD. By irradiating monitor glass SRM612 and CN5 in pairs, we will study the thermalization situation of the 492 reactor. Irradiated data show that thermal neutrons are not evenly distributed either in horizontal or in vertical dimension. Especially, horizontal heterogeneity is obvious. But we discovered that proper irradiation position in the reactor can meet the requirement of FTD. Under the current irradiation condition, we calculated and assessed the insufficient thermalization effects on determining fission-track ages. We found that the difference between the 232 Th/ 238 U ratios of samples and standards is the main factor to the experiment results. The results will not be affected if the 232 Th/ 238 U value of samples is equal to the standard samples. However, if the 232 Th/ 238 U ratio is larger than that of the standards, the results will be smaller than actual ages. Comparatively, the ages will be more than expected if the 232 Th/ 238 U ratio is less. Therefore, to reduce the irradiation error, we suggest either locating the position of irradiation strictly, or minimizing the influence of lateral heterogeneity by reducing the amount of each sample package. Additionally, accuracy of the experimental results can be improved by increasing standard samples to adjust ζ value and using the monitor of standard glass SRM612 and CN5 together.