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体外循环中血栓素B_2、6-酮-前列腺素F_(1α)的变化及抑肽酶对其影响的临
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作者 马游 吴熹 顾懋栋 《南京铁道医学院学报》 1995年第2期97-98,105,共3页
20例体外循环心内手术患者被随机分为对照组和实验组,各10例。实验组干预充液中加入抑肽酶2x106血管舒张素抑制单位(KIU)。结果发现,体外循环期间,对照组的血栓素B2(TXB2)及其与6-酮-前列腺素F1a比值(... 20例体外循环心内手术患者被随机分为对照组和实验组,各10例。实验组干预充液中加入抑肽酶2x106血管舒张素抑制单位(KIU)。结果发现,体外循环期间,对照组的血栓素B2(TXB2)及其与6-酮-前列腺素F1a比值(TXB2/6-K-PGF1a)明显升高;实验组TXB2的增加及TXB2/6-K-PGF1a的值明显低于对照组;实验组的血小板聚集率下降程度明显低于对照组,术后纵隔引流量减少41.7%。表明抑肽酶可于体外循环期间抑制TXB2的合成和释放,降低TXB2/6-K-PGF1a的值,从而保护血小板功能。 展开更多
关键词 体外循体 抑肽酶 血栓素B2 6-酮-前列腺素 F1Α
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Urgent Tracheal Resection and Reconstruction Assisted by Temporary Cardiopulmonary Bypass:a Case Report 被引量:7
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作者 Hui Gao Bin Zhu +2 位作者 Jie Yi Tie-hu Ye Yu-guang Huang 《Chinese Medical Sciences Journal》 CAS CSCD 2013年第1期55-57,共3页
SEVERE tracheal stenosis can not only cause criti- cal medical problems such as severe shortness of breath, hypoxia, and even orthopnea, but also impose overwhelming challenges on thephysicians, particularly the anest... SEVERE tracheal stenosis can not only cause criti- cal medical problems such as severe shortness of breath, hypoxia, and even orthopnea, but also impose overwhelming challenges on thephysicians, particularly the anesthesiologist. Life-threa- tening airway obstruction can make the patient's gas ex- change extremely difficult. Though several options could be offered regarding the treatment of tracheal stenosis, normally, tracheal resection and following reconstruction is the first choice for severe airway stenosis.1 Successful surgical intervention relies on the close communication and cooperation between surgeons and anesthesiologists. 展开更多
关键词 tracheal resection tracheal reconstruction temporary cardiopulmonary bypass
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A totally mini-invasive approach for colorectal laparoscopic surgery 被引量:8
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作者 Gabriele Anania Mirco Santini +6 位作者 Lucia Scagliarini Alice Marzetti Laura Vedana Serafino Marino Claudio Gregorio Giuseppe Resta Giorgio Cavallesco 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第29期3869-3874,共6页
AIM:To study the short-term outcome of patients treated with laparoscopic right colectomy and how intracorporeal anastomosis has improved the outcome.METHODS:We retrospectively examined all patients affected by colore... AIM:To study the short-term outcome of patients treated with laparoscopic right colectomy and how intracorporeal anastomosis has improved the outcome.METHODS:We retrospectively examined all patients affected by colorectal cancer who underwent a laparoscopic right colectomy between January 2006 and December 2010 in our department.Our evaluation criteria were:diagnosis of colorectal carcinoma at presurgical biopsy,elective surgery,and the same surgeon.We excluded:emergency surgery,conversions from laparotomic colectomy,and other surgeons.The endpoints we examined were:surgical time,number of lymph nodes removed,length of stay(removal of nasogastric tube,bowel movements,gas evacuation,solid and liquid feeding,hospitalization),and major complications.Seventy-two patients were divided into two groups:intracorporeal anastomosis(39 patients)and extracorporeal anastomosis(33 patients).RESULTS:Significant differences were observed between intracorporeal vs extracorporeal anastomosis,respectively,for surgical times(186.8 min vs 184.1 min,P < 0.001),time to resumption of gas evacuation(3 d vs 3.5 d,P < 0.001),days until resumption of bowel movements(3.8 d vs 4.9 d,P < 0.001),days until resumption of liquid diet(3.5 d vs 4.5 d,P < 0.001),days until resuming a solid diet(4.6 d vs 5.7 d,P < 0.001),and total hospitalization duration(7.4 d vs 8.5 d,P < 0.001).In the intracorporeal group,on average,19 positive lymph nodes were removed;in the extracorporeal group,on average,14 were removed P < 0.001).Thus,intracorporeal anastomosis for right laparoscopic colectomy improved patient outcome by providing faster recovery of nutrition,faster recovery of intestinal function,and shorter hospitalization than extracorporeal anastomosis.CONCLUSION:Short-term outcomes favor intracorporeal anastomosis,confirming that a less traumatic surgical approach improves patient outcome. 展开更多
关键词 Anastomosis Cancer Colorectal disease Surgery Laparoscopy
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