基于体模法的三维成像超声装置校准方法研究

随着计算机技术的飞速发展,三维成像超声装置取得长足进步,已经进入临床应用阶段。三维成像的技术参数有别于二维成像,国内目前还没有对应的校准规范。为确保三维成像超声装置测得参数的准确可靠,该文研究了基于体模法的三维成像超声装置校准方法,包括校准条件、校准装置、校准项目、校准方法等。结果表明该文提出的校准方法可以检测三维超声成像设备的性能,为三维成像超声装置的质量保证提供技术支持。因此该方法可以保证医疗质量,为三维成像超声装置校准规范的制定提供参考。

Three-dimensional orebody modelling and intellectualized longwall mining for stratiform bauxite deposits

Acoupled biharmonic spline and linear interpolation algorithm was proposed to create a three-dimensional smooth deposit model with minimal curvature containing grade and position data. To obtain the optimal technical parameters, such as cuttingheight and drum diameter, a virtual longwall mining procedure was modelled by simulating the actual fully mechanized longwall mining process. Based on the above work, a bauxite deposit in a longwall mining panel was modelled by scattered grade data from ores sampled on the entry wall. The deposit was then demarcated by industrial indexes and sliced according to the virtual longwallmining procedure. The results show that the proposed interpolation algorithm can depict the stratiform structure of bauxite depositsand that the uncovered bauxite deposit has high proportions of high-grade and rich ore. The ranges of optimal cutting height and drum diameters are 1.72-2.84 m and 1.42-1.72 m, respectively. Finally, an intellectualized longwall mining procedure was designed to guide the mining process with the lowest dilution and loss rates.

Self-adapting extraction of matrix mineral bulk modulus and verification of fluid substitution

Gassmann＇s equations are commonly used for predicting seismic wave velocity in rock physics research.However the input matrix mineral bulk modulus parameters are not accurate,which greatly influences the prediction reliability.In this paper,combining the Russell fluid factor with the Gassman-Biot-Geertsma equation and introducing the dry-rock Poisson＇s ratio,we propose an effective matrix mineral bulk modulus extraction method.This method can adaptively invert the equivalent matrix mineral bulk modulus to apply the Gassmann equation to fluid substitution of complex carbonate reservoirs and increase the fluid prediction reliability.The verification of the actual material fluid substitution also shows that this method is reliable,efficient,and adaptable.

基于DEM与MFBD双向耦合的农机触土部件疲劳分析

针对作业过程中农机触土部件出现断裂且实测载荷谱困难的问题,在额定工况下,对农机触土部件的疲劳强度进行了研究,提出了基于离散元法与多柔体动力学双向耦合的疲劳分析方法。以井窖制作机为例,采用非线性有限元柔性体建模法构建了其成穴钻头总成装置刚-柔耦合动力学模型,在此基础上与离散元仿真耦合,数值模拟成穴钻头-土壤相互作用过程,提取了成穴钻头的动态工作载荷谱;基于疲劳分析相关理论,利用疲劳仿真软件预测了成穴钻头的疲劳寿命。研究结果表明:触土部件成穴钻头的疲劳强度薄弱区域位于圆锥面靠小端,仿真预测的破坏区域与实际断裂位置基本吻合,证明了DEM与MFBD双向耦合的疲劳分析方法能够准确地预测成穴钻头的动态响应特性和疲劳寿命,为其疲劳强度设计提供具有价值的参考。

Simulation of texture evolution during plastic deformation of FCC,BCC and HCP structured crystals with crystal plasticity based finite element method

Two alternative formulations of single crystal plasticity model were introduced respectively and two schemes were implemented in the explicit FE code with software ABAQUS/Explicit by writing the user subroutine VUMAT.Meshes containing material data were created with solid elements.Each element represented an individual grain,and the grain orientations were explicitly stored and updated at each increment.Tangential modulus method was employed to calculate the plastic shear strain increment of deformation systems in combination with a hardening law to describe the hardening responses.Both two developed subroutines were applied to simulate the texture evolution during the uniaxial tension of copper（FCC）,cold rolling of IF steel（BCC） and uniaxial compression of AZ31 magnesium alloy（HCP）.The predicted texture distributions are in qualitative agreement with the experimental results.

MULTI-MATERIAL NUMERICAL SIMULATION OF MOVING SHOCK INTERACTING WITH CONSECUTIVE BUBBLES

Numerical simulations are performed on the interface with large deformation induced by the interaction between a moving shock and two consecutive bubbles. The high performance of the level set method for multi-material interfaces is demonstrated. Discontinuous Galerkin finite element method is used to solve Euleri- an equations. And the fifth-order weighted essentially non-oscillatory （WENO） scheme is used to solve the level set equation for capturing multi-material interfaces. The ghost fluid method is used to deal with the interfacial boundary condition. Results are obtained for two bubble interacting with a moving shock. The contours of the constant density and the pressure at different time are given. In the computational domain, three different cases are considered, i.e. two helium bubbles, a helium bubble followed by an R22 bubble in the direction of the moving shock, and an R22 bubble followed by a helium bubble. Computational results indicate that multi-mate- rial interfaces can be properly captured by the level set method. Therefore, for problems involving the flow of three different materials with two different interfaces, each interface separating two different materials can be similarly handled.

A New Method of Receptor Mapping to Predict Bioactivity

We used genetic algorithm to construct pseudoreceptor site models and made use of the high correlation between interaction energy, which was between the models and the ligands,and bioactivity data of known molecules to predict the bioactivity of unknown molecules For the system of ALS enzyme inhibitor,this emthod can give reasonable predictions of the bioactivity of ALS enzyme inhibitor.

A New Rational-based Optimal Design Strategy of Ship Structure Based on Multi-level Analysis and Super-element Modeling Method

A new multi-level analysis method of introducing the super-element modeling method, derived from the multi-level analysis method first proposed by O. F. Hughes, has been proposed in this paper to solve the problem of high time cost in adopting a rational-based optimal design method for ship structural design. Furthermore,the method was verified by its effective application in optimization of the mid-ship section of a container ship. A full 3-D FEM model of a ship,suffering static and quasi-static loads, was used as the analyzing object for evaluating the structural performance of the mid-ship module, including static strength and buckling performance. Research results reveal that this new method could substantially reduce the computational cost of the rational-based optimization problem without decreasing its accuracy, which increases the feasibility and economic efficiency of using a rational-based optimal design method in ship structural design.

Agent-Based Network Modeling Study of Immune Responses in Progression of Ulcerative Colitis

Ulcerative colitis, an inflammatory bowel disease, is a chronic inflammatory disorder that results in ulcers of the colon and rectum without known etiology. Ulcerative colitis causes a huge public health care burden particularly in developed countries. Many studies suggest that ulcerative colitis results from an abnormal immune response against components of cornrnensal rnicrobiota in genetically susceptible individuals. However, understanding of the disease mechanisms at cellular and molecular levels remains largely elusive. In this paper, a network model is developed based on our previous study and computer simulations are perforrned using an agent-based network modeling to elucidate the dynamics of immune response in ulcerative colitis progression. Our modeling study identifies several important positive feedback loops as a driving force for ulcerative colitis initiation and progression. The results demonstrate that although immune response in ulcerative colitis patients is dominated by anti-inflarnrnatory/regulatory cells such as alternatively activated rnacrophages and type II natural killer T cells, proinflarnrnatory cells including classically activated rnacrophages, T helper 1 and T helper 17 cells, and their secreted cytokines tumor necrosis factor-α, interleukin-12, interleukin-23, interleukin-17 and interferon-γ remain at certain levels （lower than those in Crohn＇s disease, another inflammatory bowel disease）. Long-terrn exposure to these proinflarnrnatory components, causes rnucosal tissue damage persistently, leading to ulcerative colitis. Our simulation results are qualitatively in agreement with clinical and laboratory measurements, offering novel insight into the disease mechanisms.

Numerical simulation and experimental study of the hydrodynamics of a modeled reef located within a current

The hydrodynamic forces and flow field of artificial reef models in steady flow were numerically investigated using the RNG κ-ε turbulent model. The numerical simulation results are consistent with results observed by experimental means. A comparative study indicates that the corresponding errors of forces between calculated values and values observed in the experiment vary in the range of2.3%-11.2% and that the corresponding errors of velocities vary in the range of 1.3%-15.8%. The flow field numerical results show that upstream and vortices exist when the current passes over and through the surface of the reef model. This study suggests that the numerical simulation method can be applied to predict the forces and flow field associated with artificial reefs.

Automatic target tracking on multi-resolution terrain

We propose a high-performance path planning algorithm for automatic target tracking in the applications of real-time simulation and visualization of large-scale terrain datasets, with a large number of moving objects （such as vehicles） tracking multiple moving targets. By using a modified Dijkstra＇s algorithm, an optimal path between each vehicle-target pair over a weighted grid-presented terrain is computed and updated to eliminate the problem of local minima and losing of tracking. Then, a dynamic path re-planning strategy using multi-resolution representation of a dynamic updating region is proposed to achieve high-performance by trading-off precision for efficiency, while guaranteeing accuracy. Primary experimental results showed that our algorithm successfully achieved l0 to 96 frames per second interactive path-replanning rates during a terrain simulation scenario with 10 to 100 vehicles and multiple moving targets.

Analysis of Static Pressure in Area between Back Plate and Cylinder of a Carding Machine with CFD

To analyze static pressure between back plate and cylinder in an A186 carding machine,a fluid model is established. The model takes into account static pressure of airflow near back plate with the numerical simulation method of Computational Fluid Dynamics (CFD) in FLUENT software. The result of the simulation in the model shows that static pressure in this area quickly increases to its maximum then rapidly decreases to a lower fixed value from inlet to outlet along a zone between back plate and cylinder. Both rotating speeds of the cylinder and the taker-in affect static pressure from the inlet to the outlet,of which the cylinder rotating speed has more influence than that of taker-in. Numerical simulations reveal that static pressure on surface of back plate are in good agreement with the former result of experimental analysis.

Characterization on the hydrodynamics of a covering-plate Rushton impeller

A modified Rushton impeller with two circular covering-plates mounted on the upper and lower sides of the blades was designed.There are gaps between the plates and the blades.The turbulent hydrodynamics was analyzed by the computational fluid dynamics(CFD) method.Firstly,the reliability of the numerical model and simulation method was verified by comparing with the experimental results from literature.Subsequently,the power consumption,flow pattern,mean velocity and mixing time of the covering-plate Rushton impeller(RT-C) were studied and compared with the standard Rushton impeller(RT) operated under the same conditions.Results show that the power consumption can be decreased about 18%.Compared with the almost unchanged flow field in the lower stirred tank,the mean velocity was increased at the upper half of the stirred tank.And in the impeller region,the mean axial and radial velocities were increased,the mean tangential velocity was decreased.In addition,the average mixing time of RT-C was shortened about 4.14% than the counterpart of RT.The conclusions obtained here indicated that RT-C has a more effective mixing performance and it can be used as an alternative of RT in the process industries.

Accurate level set method for simulations of liquid atomization

Computational fluid dynamics is an efficient numerical approach for spray atomization study, but it is challenging to accurately capture the gas-liquid interface. In this work, an accurate conservative level set method is intro- duced to accurately track the gas-liquid interfaces in liquid atomization. To validate the capability of this method, binary drop collision and drop impacting on liquid film are investigated. The results are in good agreement with experiment observations. In addition, primary atomization （swirling sheet atomization） is studied using this method. To the swirling sheet atomization, it is found that Rayleigh-Taylor instability in the azimuthal direction causes the primary breakup of liquid sheet and complex vortex structures are clustered around the rim of the liq- uid sheet. The effects of central gas velocity and liquid-gas density ratio on atomization are also investigated. This work lays a solid foundation for further studvin~ the mechanism of s^rav atomization.

Numerical Simulation of Separating Gas Mixtures via Hydrate Formation in Bubble Column

To develop a new technique for separating gas mixtures via hydrate formation,a set of medium-sized experimental bubble column reactor equipment was constructed.On the basis of the structure parameters of the ex- perimental bubble column reactor,assuming that the liquid phase was in the axial dispersion regime and the gas phase was in the plug flow regime,in the presence of hydrate promoter tetrahydrofuran(THF),the rate of hydrogen enrichment for CH4+H2 gas mixtures at different operational conditions(such as temperature,pressure,concentra- tion of gas components,gas flow rate,liquid flow rate)were simulated.The heat product of the hydrate reaction and its axial distribution under different operational conditions were also calculated.The results would be helpful not only to setting and optimizing operation conditions and design of multi-refrigeration equipment,but also to hydrate separation technique industrialization.

A method based on mutual information and gradient information for medical image registration

Mutual information is widely used in medical image registration, because it does not require preprocessing the image. However, the local maximum problem in the registration is insurmountable. We combine mutual information and gradient information to solve this problem and apply it to the non-rigid deformation image registration. To improve the accuracy, we provide some implemental issues, for example, the Powell searching algorithm, gray interpolation and consideration of outlier points. The experimental results show the accuracy of the method and the feasibility in non-rigid medical image registration.

Numerical simulation of nitrogen injection of goaf in fire prevention based on Finite Volume Method

The numerical simulation is used to research the influence of nitrogen injection on spontaneous combustion in goaf. The spontaneous combustion mathematical model on the coupling of air flow field, oxygen concentration field, and residual coal temperature field was established with nitrogen injection in goat＇. Then the software of numerical computation was pro- grammed by Finite Volume Method. Combined with the example, the distributions of air flow field, oxygen concentration field and residual coal temperature field at different nitrogen injection volume were obtained by the software. The results show that the nitrogen injection could effectively prevent the spontaneous combustion fire in goaf and the highest temperature in goaf decreased with the nitrogen injection volume increasing. Finally, the accuracy of the numerical simulation was verified by the temperature observation in field. The achievement of this research is of theoretical and practical significance for the prevention of coal spontaneous combustion in goaf.

Simulation and Scale-up of Barium Sulphate Precipitation Process Using CFD Modeling

Some empirical mixing models were used to describe the imperfect mixing in precipitation process. However, the models can not, in general, reflect the details of interactions between mixing and crystallization in a vessel. In this study, CFD (computational fluid dynamics) technique were developed by simulating the precipitation of barium sulphate in stirred tanks by integration of population balance equations with a CFD solver. Two typical impellers, Rushton and pitched blade turbines, were employed for agitation. The influence of feed concentration and position on crystal product properties was investigated by CFD simulation. The scale-up of these precipitators was systematically studied. Significant effect on the crystal properties was found for the scale-up under some conditions.

Numerical Simulations of Structural Deformation and Fluid Flow in Xiangshan Deposit

The Xiangshan deposit in Jiangxi province is one of the most important uranium deposits in China. The aim of this study is to achieve a better understanding of mineralization in the Xiangshan deposit through numerical simulation. In order to find the most favorable locations of mineralization and to help further mineral exploration, a coupling deforma- tion and fluid flow model has been established to describe the mineralization process. In this model, the simulation re- constructs the strata deformations under fields of compressive stress and thrust structure on the hanging wall of the Zou-Shi fault. Compared with practical information, the simulation results are consistent with the No. 51 exploration section of the western Xiangshan. In addition, on the basis of geological information provided by previous investigators, the model simulates the flow process of fluids under compressive stress fields. The result suggests that many tensional areas are formed, which can help the fluid flowing upward from deeper parts. The fluid is easy to concentrate on the breccia fractured zone between two volcanic layers, especially on the intersection parts with faults, resulting in the for- mation of favourable locations of mineralization. In addition, the model is significant in guiding the exploration of ura- nium deposits in the western Xiangshan and provides clues for further exploration of deposits.

Numerical simulation of three-dimensional combustion flows

A finite-rate method is used to simulate the three-dimensional combustion process in a plasma generator with CH4 as the fuel. The simulation was run with RNG k-ε model to simulate turbulence, with eddy-dissipation-concept (EDC) model to simulate the combustion and with discrete ordinates model to simulate radiation. The numerical results show that the flow field characteristics and the parameter distributions are under the condition of rich fuels, and these results provide valuable information when optimizing the plasma generator design and organizing its flow fields.