赛艇是由1名或多名桨手坐在舟艇上,背向舟艇前进的方向,运用其肌肉力量,通过桨和桨架简单杠杆作用进行划水,使舟艇前进的一项水上运动,其不仅是现今大型运动比赛中的重要项目,也是我国重点开展的体育项目之一。根据项目特点,赛艇运动对...赛艇是由1名或多名桨手坐在舟艇上,背向舟艇前进的方向,运用其肌肉力量,通过桨和桨架简单杠杆作用进行划水,使舟艇前进的一项水上运动,其不仅是现今大型运动比赛中的重要项目,也是我国重点开展的体育项目之一。根据项目特点,赛艇运动对于运动员的体能具有较高的要求,赛艇运动员的肺活量更是在各项体育项目中占第一位,可达7 000 m L,有人把赛艇运动称为肺部体操。为了更好地对我国女子赛艇运动员的体能进行评价,在该文中,将就中国优秀女子赛艇运动员体能诊断与评价方法进行一定的分析与研究。展开更多
AIM: To investigate the existence and levels of sH2a, a soluble secreted form of the asialoglycoprotein receptor in human serum. METHODS: Production of recombinant sH2a and development of a monoclonal antibody and an ...AIM: To investigate the existence and levels of sH2a, a soluble secreted form of the asialoglycoprotein receptor in human serum. METHODS: Production of recombinant sH2a and development of a monoclonal antibody and an enzyme-linked immunosorbent assay (ELISA). This assay was used to determine the presence and concentration of sH2a in human sera of individuals of both sexes and a wide range of ages. RESULTS: The recombinant protein was produced successfully and a specific ELISA assay was developed. The levels of sH2a in sera from 62 healthy individuals variedminimally (147 ± 19 ng/mL). In contrast, 5 hepatitis C patients with cirrhosis showed much decreased sH2a levels (50 ± 9 ng/mL). CONCLUSION: Constant sH2a levels suggest constitutive secretion from hepatocytes in healthy individuals. This constant level and the decrease with cirrhosis suggest a diagnostic potential.展开更多
Individual inorganic nanoparticles （NPs） have been widely used in the fields of drug delivery, cancer imaging and therapy. There are still many hurdles that limit the performance of individual NPs for these applicat...Individual inorganic nanoparticles （NPs） have been widely used in the fields of drug delivery, cancer imaging and therapy. There are still many hurdles that limit the performance of individual NPs for these applications. The utilization of highly ordered NP ensembles opens a door to resolve these problems, as a result of their new or advanced collective properties. The assembled NPs show several advantages over individual NP-based systems, such as improved cell internalization and tumor targeting, enhanced multimodality imaging capability, superior combination therapy arising from synergistic effects, possible complete clearance from the whole body by degradation of assemblies into original small NP building blocks, and so on. In this review, we discuss the potential of utilizing assembled NP ensembles for cancer imaging and treatment by taking plasmonic vesicular assemblies of Au NPs as an example. We first summarize the recent developments in the self-assembly of plasmonic vesicular structures of NPs from amphiphilic polymer-tethered NP building blocks. We further review the utilization of plasmonic vesicles of NPs for cancer imaging （e.g. multi-photon induced luminescence, photothermal, and photoacoustic imaging）, and cancer therapy （e.g., photothermal therapy, and chemotherapy）. Finally, we outline current challenges and our perspectives along this line.展开更多
文摘赛艇是由1名或多名桨手坐在舟艇上,背向舟艇前进的方向,运用其肌肉力量,通过桨和桨架简单杠杆作用进行划水,使舟艇前进的一项水上运动,其不仅是现今大型运动比赛中的重要项目,也是我国重点开展的体育项目之一。根据项目特点,赛艇运动对于运动员的体能具有较高的要求,赛艇运动员的肺活量更是在各项体育项目中占第一位,可达7 000 m L,有人把赛艇运动称为肺部体操。为了更好地对我国女子赛艇运动员的体能进行评价,在该文中,将就中国优秀女子赛艇运动员体能诊断与评价方法进行一定的分析与研究。
基金Supported by The Ramot research fundthe Israel Science Foundationthe Israel Cancer Association and the Israeli Ministry of Health (to Lederkremer GZ)
文摘AIM: To investigate the existence and levels of sH2a, a soluble secreted form of the asialoglycoprotein receptor in human serum. METHODS: Production of recombinant sH2a and development of a monoclonal antibody and an enzyme-linked immunosorbent assay (ELISA). This assay was used to determine the presence and concentration of sH2a in human sera of individuals of both sexes and a wide range of ages. RESULTS: The recombinant protein was produced successfully and a specific ELISA assay was developed. The levels of sH2a in sera from 62 healthy individuals variedminimally (147 ± 19 ng/mL). In contrast, 5 hepatitis C patients with cirrhosis showed much decreased sH2a levels (50 ± 9 ng/mL). CONCLUSION: Constant sH2a levels suggest constitutive secretion from hepatocytes in healthy individuals. This constant level and the decrease with cirrhosis suggest a diagnostic potential.
文摘Individual inorganic nanoparticles （NPs） have been widely used in the fields of drug delivery, cancer imaging and therapy. There are still many hurdles that limit the performance of individual NPs for these applications. The utilization of highly ordered NP ensembles opens a door to resolve these problems, as a result of their new or advanced collective properties. The assembled NPs show several advantages over individual NP-based systems, such as improved cell internalization and tumor targeting, enhanced multimodality imaging capability, superior combination therapy arising from synergistic effects, possible complete clearance from the whole body by degradation of assemblies into original small NP building blocks, and so on. In this review, we discuss the potential of utilizing assembled NP ensembles for cancer imaging and treatment by taking plasmonic vesicular assemblies of Au NPs as an example. We first summarize the recent developments in the self-assembly of plasmonic vesicular structures of NPs from amphiphilic polymer-tethered NP building blocks. We further review the utilization of plasmonic vesicles of NPs for cancer imaging （e.g. multi-photon induced luminescence, photothermal, and photoacoustic imaging）, and cancer therapy （e.g., photothermal therapy, and chemotherapy）. Finally, we outline current challenges and our perspectives along this line.
