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晋北平鲁方言的语气副词“作准”及其来源
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作者 赵锦秀 《汉语学报》 CSSCI 北大核心 2022年第3期110-119,共10页
晋北平鲁方言语气副词“作准”表不确定的揣测语气,确认度高。能与多种句法成分共现,还可根据强调焦点的不同,灵活改变其位置。“作准”的同素逆序词“准作”,否定形式“不作准”也能表示揣测语气。结合历史文献发现,不晚于唐代,“作准... 晋北平鲁方言语气副词“作准”表不确定的揣测语气,确认度高。能与多种句法成分共现,还可根据强调焦点的不同,灵活改变其位置。“作准”的同素逆序词“准作”,否定形式“不作准”也能表示揣测语气。结合历史文献发现,不晚于唐代,“作准”由动词短语词汇化为动词,表“确定”“当真”等义,为语气副词“作准”提供语义基础。明代以后,“作准”虚化为语气副词,表确定语气。清代“作准”在否定句和反问句中吸收不确定的语境义,发展出不确定的揣测语气。这一历时演变过程是重新分析、主观性程度增强及语境感染共同作用的结果。晋北平鲁方言语气副词“作准”表不确定揣测语气,是对明清用法的继承与发展。 展开更多
关键词 平鲁方言 作准 语气副词 来源
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《公民及政治权利国际公约》中文作准本问题研究 被引量:7
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作者 杨宇冠 《政法论坛》 CSSCI 北大核心 2021年第3期25-35,共11页
《公民及政治权利国际公约》(International Covenant on Civil and Political Rights)是联合国制定的最重要的人权公约。它不是规定国际法主体之间相互的权利义务关系,而是规定了个人的各种重要权利和该公约成员国共同承担保障个人权... 《公民及政治权利国际公约》(International Covenant on Civil and Political Rights)是联合国制定的最重要的人权公约。它不是规定国际法主体之间相互的权利义务关系,而是规定了个人的各种重要权利和该公约成员国共同承担保障个人权利的责任。该公约有不同的中文本,主要有三个:第一个是1966年通过时的文本,称《公民及政治权利国际盟约》;第二个是2002年联合国秘书长应中国政府要求将原中文本的"盟约"一词改为"公约"(以下在不引起歧义的情况下,皆简称为"该公约"),并通知世界各国,将该公约中文名称改为《公民及政治权利国际公约》的文本;第三个文本时间和来源不详,是国内外广泛流传和引用的现代汉语文本,称《公民权利和政治权利国际公约》。该公约还有其他若干不同文本,主要是标题名称的不同,此处不作详细论述。(1)这三个文本中只有第二个中文本,即《公民及政治权利国际公约》是具有法律效力的文本,其他中文本不应当同时具有法律效力。该公约的中文本实际上是根据该公约英文本翻译而成的,而且都存在不少翻译痕迹和错误。中国已经签署了该公约,(2)应当根据法律程序确定符合中国法律和文字风格的作准本,并应当经过联合国的法律程序颁布于世,以昭信守。此公约合法中文本的确定不仅关系到每个人的权利和国家的义务,而且也是国家相关部门研究批准该公约的依据,同时也应当是法学界研究该公约的依据。 展开更多
关键词 公民及政治权利国际公约 中文本 作准 人权保障
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晚清中外条约作准文本探析 被引量:4
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作者 郭卫东 《历史研究》 CSSCI 北大核心 2019年第5期61-74,190,共15页
条约是隆重煌煌的国际交换文件,签约所用语言代表着国家沟通的官方语言。清代以来,中外条约作准文本有所演变:鸦片战争之前,以缔约方或第三方的文字为准,体现了平等理念。战后,不平等成为约章主调,但出于传统习惯,汉文本仍是依准本。至1... 条约是隆重煌煌的国际交换文件,签约所用语言代表着国家沟通的官方语言。清代以来,中外条约作准文本有所演变:鸦片战争之前,以缔约方或第三方的文字为准,体现了平等理念。战后,不平等成为约章主调,但出于传统习惯,汉文本仍是依准本。至1858年的中英《天津条约》,作准文本改头换面,开启外文本在中外条约中居于基准的时代,这是列强对中国的语文强加。不能夸大清朝统治在条约文本中的“民族”成分与“种族”色彩,有清一朝,就约本来看,清朝统治者并没有突出的“国语”意识。 展开更多
关键词 清代 中外条约 作准文本
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《经济社会文化权利国际公约》的中文文本问题及其可能化解途径 被引量:1
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作者 黄金荣 《法治研究》 2018年第3期134-144,共11页
目前联合国主要机构和中国使用的《经济社会文化权利国际公约》中文文本并非是该公约的中文作准文本,而是一个来源不明的中文文本,两者在语义、语言风格以及对《公约》名称的使用上均存在较大的差异。与《公约》中文作准本相比,《公约... 目前联合国主要机构和中国使用的《经济社会文化权利国际公约》中文文本并非是该公约的中文作准文本,而是一个来源不明的中文文本,两者在语义、语言风格以及对《公约》名称的使用上均存在较大的差异。与《公约》中文作准本相比,《公约》中文通行本不仅不具有法律效力,而且还存在比较严重的翻译问题,从而可能会对《公约》适用带来很大的困扰。中国政府应考虑建议联合国弃用《公约》中文通行本并转而使用中文作准本,并通过启动条约的更正程序使《公约》中文作准本的某些不符合现代汉语习惯的语言得以更正。 展开更多
关键词 《经济社会文化权利国际公约》 中文作准 中文通行本 翻译错误 更正程序
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Research and Application of Maize Precision Intelligence Spatial Decision Support System
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作者 王国伟 陈桂芬 +1 位作者 姚玉霞 闫丽 《Agricultural Science & Technology》 CAS 2010年第6期147-151,188,共6页
In order to solve the problem of the maze precision fertilizer,soil fertility evaluation,soil fertility classify and yield projections,the geographic information system with spatial information processing functions,sp... In order to solve the problem of the maze precision fertilizer,soil fertility evaluation,soil fertility classify and yield projections,the geographic information system with spatial information processing functions,spatial data mining techniques with spatial information analysis capabilities,expert system technology in the field of artificial intelligence,traditional information management systems and decision support system were effectively integrated in this study,and the statistical analysis method of GIS and data visualization were combined to design and implement the maize precise intelligent space decision-making system.This system had greatly improved the decision-making ability in agricultural production carried out by agricultural management. 展开更多
关键词 Maize precision operation Space data mining Decision support system Geographic information system VISUALIZATION
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Thoughts on Establishment of the Agricultural Products Quality and Safety(Standards) Cooperation Center in Asia-Pacific Region
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作者 章力建 陈天金 李鹏 《China Standardization》 2012年第2期45-49,共5页
The establishment of agricultural products quality and safety cooperation mechanism and the research demonstration center in the Asia-Pacific reg coordinating each other, is not only of great ening cooperation with co... The establishment of agricultural products quality and safety cooperation mechanism and the research demonstration center in the Asia-Pacific reg coordinating each other, is not only of great ening cooperation with countries in Asia-Pacific region and for agricultural production safety of those countries in Asia- Pacific region, but also very necessary for our country to build a responsible image in the quality and safety of agricultural products, protection of the benefit of agriculture-related enterprises, increasing exports, ensuring imported food safety and China's national food security, as Well as nice exploration of establishing the global agricultural' products quality and safety cooperation center. 展开更多
关键词 the Asia-Pacific region the quality and safety &agricultural products STANDARDIZATION cooperation mechanisms
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Effects of Written Corrective Feedback on College EFL Students’Writing Accuracy and Linguistic Knowledge Acquisition 被引量:1
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作者 Haiyang SUN Wenbo QI 《Chinese Journal of Applied Linguistics》 2022年第3期445-461,486,共18页
Set at the interface between second language acquisition and second language writing,this study examines how different types of written corrective feedback(WCF)influence the writing accuracy of Chinese college student... Set at the interface between second language acquisition and second language writing,this study examines how different types of written corrective feedback(WCF)influence the writing accuracy of Chinese college students learning English as a Foreign Language(EFL)and whether WCF facilitates the students’grasp of the focused linguistic knowledge.The participants(n=60)were divided into direct correction group(n=20),indirect error-coding group(n=20)and metalinguistic explanation group(n=20).The three groups wrote four essays in two months and received WCF for the first three essays on the five targeted error types,namely tense errors,confusion of different forms of a word,word(articles,prepositions,etc.)missing,errors in subjectverb agreement and inappropriate verb-noun collocations.The results show that all three types of WCF improved students’writing accuracy but none of them had any statistical advantage,and the metalinguistic WCF was more effective than the other two forms in facilitating the acquisition of the targeted linguistic features.These results shed some light on teaching and consolidation of language points through writing in EFL contexts. 展开更多
关键词 written corrective feedback feedback for accuracy feedback for acquisition writing accuracy explicit knowledge
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Analysis on Impacts and Co-Abatement Effects of Implementing the Low Carbon Cement Standard 被引量:3
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作者 PANG Jun SHI Yuan-Chang +2 位作者 FENG Xiang-Zhao WU Shi-Yu SUN Wen-Long 《Advances in Climate Change Research》 SCIE 2014年第1期41-50,共10页
Based on the MAP-CGE model,this paper simulated the impacts on the output,energy consumption and pollutant emissions of different cement production processes when implementing a low carbon cement standard in China.It ... Based on the MAP-CGE model,this paper simulated the impacts on the output,energy consumption and pollutant emissions of different cement production processes when implementing a low carbon cement standard in China.It also calculated the impacts on the marginal abatement cost and equilibrium price of the cement industry,and analyzed the co-abatement effects of different pollutants.The results showed that implementing the low carbon cement standard will be beneficial in promoting an upgrading of cement production processes,and strengthening the energy conservation and emission reduction in the cement industry.If there is no change in the existing technology,the cement industry will reduce SO2emissions by 1.17 kg and NOxemissions by 4.44 kg per ton of CO2emission reduction.Implementing low carbon cement standard can also promote NOxabatement in the cement industry.However,the cement industry will bear the abatement costs,and their equilibrium price will increase slightly. 展开更多
关键词 low carbon cement standard co-abatement effects MAP-CGE model
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Three-dimensional endoanal ultrasonographic assessment of an anal fistula with and without H_2O_2 enhancement 被引量:25
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作者 Yung Kim Young Jin Park 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第38期4810-4815,共6页
AIM: To evaluate the effectiveness of three-dimensional endoanal ultrasound (3D-EAUS) in the assessment of anal fistulae with and without H202 enhancement. METHODS: Sixty-one patients (37 males, aged 17-74 years... AIM: To evaluate the effectiveness of three-dimensional endoanal ultrasound (3D-EAUS) in the assessment of anal fistulae with and without H202 enhancement. METHODS: Sixty-one patients (37 males, aged 17-74 years) with anal fistulae, which were not simple low types, were evaluated by physical examination and 3D-EAUS with and without enhancement. Fistula classification was determined with each modality and compared to operative findings as the reference standard. RESULTS: The accuracy of 3D-EAUS was significantly higher than that of physical examination in detecting the primary tract (84.4% vs 68.7%, P = 0.037) and secondary extension (81.8% vs 62.1%, P = 0.01) and localizing the internal opening (84.2% vs 59.7%, P = 0.004). A contrast study with H202 detected several more fistula components including two primary suprasphincteric fistula tracks and one supralevator secondary extension, which were not detected on non-contrast study. However, there was no significant difference in accuracy between 3D-EAUS and H202- enhanced 3D-EAUS with respect to classification of the primary tract (84.4% vs 89.1%, P = 0.435) or secondary extension (81.8% vs 86.4%, P = 0.435) or localization of the internal opening (84.2% vs 89.5%, P = 0.406). CONCLUSION: 3D-EAUS was highly reliable in the diagnosis of an anal fistula. H2O2 enhancement was helpful at times and selective use in difficult cases may be economical and reliable. 展开更多
关键词 Anal fistula Endoanal ultrasound H2O2enhancement
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Application of video-assisted thoracic surgery in the standard operation for thoracic tumors 被引量:9
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作者 Ju-Wei Mu Gui-Yu Chen +22 位作者 Ke-Lin Sun Da-Wei Wang Bai-Hua Zhang Ning Li Fang Lv You-Sheng Mao Qi Xue Shu-Geng Gao Jun Zhao Da-Li Wang Zhi-Shan Li Wen-Dong Lei Yu-Shun Gao Liangze Zhang Jin-Feng Huang Kang Shao Kai Su Kun Yang Liang Zhao Fei-Yue Feng Yong-Gang Wang Jian Li Jie He 《Cancer Biology & Medicine》 SCIE CAS CSCD 2013年第1期28-35,共8页
Objective: To evaluate the short-term outcomes of video-assisted thoracic surgery (VATS) for thoracic tumors. Methods: The data of 1,790 consecutive patients were retrospectively reviewed. These patients underwent... Objective: To evaluate the short-term outcomes of video-assisted thoracic surgery (VATS) for thoracic tumors. Methods: The data of 1,790 consecutive patients were retrospectively reviewed. These patients underwent VATS pulmonary resections, VATS esophagectomies, and VATS resections of mediastinal tumors or biopsies at the Cancer Institute & Hospital, Chinese Academy of Medical Sciences between January 2009 and January 2012. Results: There were 33 patients converted to open thoracotomy (OT, 1.84%). The overall morbidity and mortality rate was 2.79% (50/1790) and 0.28% (5/1790), respectively. The overall hospitalization and chest tube duration were shorter in the VATS lobectomy group (n=949) than in the open thoracotomy (OT) lobectomy group (n=753). There were no significant differences in morbidity rate, mortality rate and operation time between the two groups. In the esophageal cancer patients, no significant difference was found in the number of nodal dissection, chest tube duration, morbidity rate, mortality rate, and hospital length of stay between the VATS esophagectomy group (n=8 1) and open esophagectomy group (n=81). However, the operation time was longer in the VATS esophagectomy group. In the thymoma patients, there was no significant difference in the chest tube duration, morbidity rate, mortality rate, and hospital length of stay between the VATS thymectomy group (n=41) and open thymectomy group (n=41). However, the operation time was longer in the VATS group. The median tumor size in the VATS thymectomy group was comparable with that in the OT group. Conclusions: In early-stage (Ⅰ/Ⅱ) non-small cell lung cancer patients who underwent lobectomies, VATS is comparable with the OT approach with similar short-term outcomes. In patients with resectable esophageal cancer, VATS esophagectomy is comparable with OT esophagectomy with similar morbidity and mortality. VATS thymectomy for Masaoka stage I and II thymoma is feasible and safe, and tumor size is not contraindicated. Longer follow-ups are needed to determine the oncologic equivalency of VATS lobectomy, esophagectomy, and thymectomy for thymoma vs. OT. 展开更多
关键词 Video-assisted thoracic surgery (VATS) non-small cell lung cancer (NSCLC) esophageal cancer THYMOMA
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Chemical Criteria to Assess Risk of Phosphorus Leaching from Urban Soils 被引量:19
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作者 ZHANGGan-Lin W.BURGHARDT YANGJin-Ling 《Pedosphere》 SCIE CAS CSCD 2005年第1期72-77,共6页
Soils from urban and suburban areas are normally enriched with phosphorus (P). Sixteen urban soils with a wide range of total P concentrations under typical urban land uses were sampled and analyzed for extractable P ... Soils from urban and suburban areas are normally enriched with phosphorus (P). Sixteen urban soils with a wide range of total P concentrations under typical urban land uses were sampled and analyzed for extractable P concentrations using water, sodium bicarbonate and citric acid. Meanwhile the soils were artificially leached in columns and P concentrations in the leachates were determined. With linear regression a two-stage linear relationship was found to exist between concentrations of P in the leachates … 展开更多
关键词 ASSESSMENT LEACHING PHOSPHORUS urban soils
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Studying the Experience of Developed Countries to Develop Chinese Food Standardization 被引量:1
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作者 Liu Zhenghao & Su Limin 《China Standardization》 2009年第1期20-24,共5页
The food standardization statusquo and development trend of developedcountries,such as the U.S.,Canada,Japan,etc.are analyzed and researched in this paper.Some practical and effective measuresthat should be taken in t... The food standardization statusquo and development trend of developedcountries,such as the U.S.,Canada,Japan,etc.are analyzed and researched in this paper.Some practical and effective measuresthat should be taken in the food standardizationof China are advised to promote the expeditiousdevelopment of China's food standardization,to improve food quality and safetyand to increase the international competitionof food industry in China. 展开更多
关键词 food standardization devel-oped countries China measures
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A model of Korotkoff sounds method electronic sphygmomanometer equivalent to the mercury one 被引量:1
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作者 Xin Xuegang 《Journal of Medical Colleges of PLA(China)》 CAS 2010年第1期19-23,共5页
Mercury sphygmomanometer (MSM) is reliable and widely used in clinics and hospitals. The principle of Korotkoff sounds method (KSM) applied in the MSM is also a gold standard to measure blood pressure. Many efforts ha... Mercury sphygmomanometer (MSM) is reliable and widely used in clinics and hospitals. The principle of Korotkoff sounds method (KSM) applied in the MSM is also a gold standard to measure blood pressure. Many efforts have been made attempting to replace MSM, which is criticized for being not healthy and safe. In this research, an electronic blood pressure monitor, named K-sounds electronic sphygmomanometer (KESM), was designed as a substitute to MSM. The three key elements of KSM were proposed for the first time. We used appropriate electronic components to build the KESM which can fulfill the functions related to the three key elements. The KESM, which was easy to operate and free of mercury, followed the same principle as MSM. The same principle guaranteed the comparable accuracy. We took equivalence test and the results showed that the designed KESM was as accurate as the calibrated standard MSM. The designed KESM passed the certifications of SFDA and is qualified in clinics or hospitals for diagnostic purposes. 展开更多
关键词 AUSCULTATION Blood pressure monitor Equipment design OSCILLOMETRY
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Influence of The Belt and Road Initiative on Oil and Gas Infrastructure 被引量:1
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作者 Jiang Xinmin Li Mingguang Sun Ruihao 《China Oil & Gas》 CAS 2016年第2期23-29,共7页
China has proposed the "Belt and Road Initiative (B&R)" in 2013. One its core strategies is international oil/gas cooperation. This paper addresses the status quo of cooperation on oil/gas infrastructure with co... China has proposed the "Belt and Road Initiative (B&R)" in 2013. One its core strategies is international oil/gas cooperation. This paper addresses the status quo of cooperation on oil/gas infrastructure with countries along the line of "B&R', anticipahs the cooperatiorl prospect. On this basis, the author analyzes China's advantages and cooperation basis in this domain, conceives the practical way of cooperation on oil/gas infrastructure with countries along the line of "B&R'. This paper also elaborates on tlre potential risks, risk evaluation criteria and risk corr trol in oil/gas infrastructu re cooperation with countries tries along tire line of "B&R". 展开更多
关键词 Belt and Road Initiative Oil/gas infrastructure Oil/gas international cooperation Market risk COUNTERMEASURES
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New perspectives in the treatment of advanced or metastatic gastric cancer 被引量:41
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作者 Gerardo Rosati Domenica Ferrara Luigi Manzione 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第22期2689-2692,共4页
Metastatic gastric cancer remains an incurable disease,with a relative 5-year survival rate of 7%-27%.Chemotherapy,which improves overall survival(OS) and quality of life,is the main treatment option.Metaanalysis has ... Metastatic gastric cancer remains an incurable disease,with a relative 5-year survival rate of 7%-27%.Chemotherapy,which improves overall survival(OS) and quality of life,is the main treatment option.Metaanalysis has demonstrated that the best survival results obtained in earlier randomized studies were achieved with three-drug regimens containing a fluoropyrimidine,an anthracycline,and cisplatin(ECF).Although there has been little progress in improving median OS times beyond the 9-mo plateau achievable with the standard regimens,the availability of newer agents has provided some measure of optimism.A number of new combinations incorporating docetaxel,oxaliplatin,capecitabine,and S-1 have been explored in randomized trials.Some combinations,such as epirubicin-oxaliplatin-capecitabine,have been shown to be as effective as(or perhaps more effective than) ECF,and promising early data have been derived for S-1 in combination with cisplatin.One factor that might contribute to extending median OS is the advancement whenever possible to second-line cytotoxic treatments.However,the biggest hope for signif icant survival advances in the near future would be the combination of new targeted biological agents with existing chemotherapy f irst-line regimens. 展开更多
关键词 Advanced gastric cancer Biological agents CHEMOTHERAPY
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Recalibration of working standard lamps
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作者 E M El-Moghazy F M EL-Sharkawy Alaa-Eldin Abd-Elmageed 《Journal of Measurement Science and Instrumentation》 CAS CSCD 2016年第3期291-296,共6页
In the present work, recalibration of the National Institute for Standards (NIS, Egypt) working standard lamps from Osram Inc. and their associated expanded uncertainty budget were done. A set-up composed of ... In the present work, recalibration of the National Institute for Standards (NIS, Egypt) working standard lamps from Osram Inc. and their associated expanded uncertainty budget were done. A set-up composed of an integrating sphere, a standard photometer and a group of five luminous flux standard lamps ranged from 25 to 200 W calibrated and traceable to the National Physical Laboratory (NPL, UK) is used to measure and recalibrate the total luminous flux for these five working standard lamps. After recalibration, NIS (Egypt) maintains the national scales for luminous flux in lumen. 展开更多
关键词 luminous flux working standard lamps standard photomer integrating sphere
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Secrecy Performance of Untrusted Relay’s Cooperation under Fading Channels 被引量:2
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作者 付晓梅 张立 +1 位作者 王大维 侯永宏 《Transactions of Tianjin University》 EI CAS 2011年第6期440-445,共6页
The secrecy performance of cooperation with an untrusted relay under a quasi-static fading channel is analyzed in this paper. An achievable secrecy rate is provided and the influence of selfish behavior of untrusted r... The secrecy performance of cooperation with an untrusted relay under a quasi-static fading channel is analyzed in this paper. An achievable secrecy rate is provided and the influence of selfish behavior of untrusted relay is analyzed. Furthermore, the secrecy performance of the scheme is discussed and compared with that of the case where the relay is just an eavesdropper. Simulation results show that the untrusted relay's cooperation in the fading case reduces the outage probability from 1/2 to 1/3 and achieves a higher outage secrecy capacity. 展开更多
关键词 physical layer security secrecy rate outage secrecy capacity
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Exploration of Influential People for Viral Marketing 被引量:1
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作者 Muhammad Azam Zia Zhongbao Zhang +2 位作者 Liutong Chen Muhammad Hashim Sen Su 《China Communications》 SCIE CSCD 2018年第5期138-148,共11页
Exploration of influential people is really a hot issue for effective viral marketing these days. Prior studies overlooked to consider the influence of interaction between users and the authority of users during infor... Exploration of influential people is really a hot issue for effective viral marketing these days. Prior studies overlooked to consider the influence of interaction between users and the authority of users during information dissemination. In this article, we proposed an innovative concept by employing communication strength and authority in order to explore the influential people. First, we calculated communication strength by three kinds of actions including retweets, comments and mentions. Second, we deliberated authority metric by employing total times getting re-tweeted, number of tweets and followers of a user. Then, we propose a novel algorithm called Influential People Label Propagation Algorithm(IPLPA) that considers the proposed metric to explore the influential people in micro-blog networks. We performed extensive experiments to measure the influence and rank of each person within micro-blog network. The comparative study presents that IPLPA depicted effective people while baseline algorithms retrieved low influenced people at top rank. Additionally, influence dissemination also measured for obtained influential people in order to validate proposed concept. The findings of this study would be useful for viral marketing and advertisement campaigns. 展开更多
关键词 micro-blog network communication strength AUTHORITY IPLPA
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FibroSURE^(TM) and FibroScan~ in relation to treatment response in chronic hepatitis C virus 被引量:4
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作者 Keyur Patel Mireen Friedrich-Rust +13 位作者 Yoav Lurie Mircea Grigorescu Carol Stanciu Chuan-Mo Lee Eugene R Schiff Dieter Hussinger Michael P Manns Guido Gerken Isabelle Colle Michael Torbenson Erik Pulkstenis G Mani Subramanian John G McHutchison Stefan Zeuzem 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第41期4581-4589,共9页
AIM:To compare histological endpoint assessment using noninvasive alternatives to biopsy during treatment in a chronic hepatitis C virus(HCV)cohort.METHODS:Patients with chronic HCV were randomized to receive interfer... AIM:To compare histological endpoint assessment using noninvasive alternatives to biopsy during treatment in a chronic hepatitis C virus(HCV)cohort.METHODS:Patients with chronic HCV were randomized to receive interferon-based therapy for 24(genotypes 2/3)or 48(genotype 1)wk.FibroSURE~TM(FS)was assessed at baseline and at week-12 post-treatment follow-up.Baseline biopsy for METAVIR was assessed by a single pathologist.FibroScan~ transient elastogra-phy(TE)was performed during treatment in a patient subset.RESULTS:Two thousand and sixty patients(n = 253 in Asia)were classif ied as METAVIR F0-1(n = 1682)or F2-4(n = 378).For F2-4,FS(n = 2055)had sensitiv-ity and specif icity of 0.87 and 0.61,respectively,with area under the receiver-operating curve of 0.82;corre-sponding values for TE(n = 214)and combined FS/TE(n = 209)were 0.77,0.88 and 0.88,and 0.93,0.68 and 0.88.Overall FS/TE agreement for F2-4 was 71%(κ = 0.41)and higher in Asians vs non-Asians(κ = 0.86 vs 0.35;P < 0.001).Combined FS/TE had 97% accuracy in Asians(n = 33).Baseline FS(0.38 vs 0.51,P < 0.001)and TE(8.0 kPa vs 11.9 kPa,P = 0.006)scores were lower in patients with sustained virological response than in nonresponders,and were maintained through follow-up.CONCLUSION:FS and TE may reliably differentiate mild from moderate-advanced disease,with a potential for high diagnostic accuracy in Asians with chronic HCV. 展开更多
关键词 Albinterferon alfa-2b FIBROSCAN FibroSURE Hepatitis C virus INTERFERON Sustained virological response -Transient elastography
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Age-dependent impact of the SYNTAX-score on longer-term mortality after percutaneous coronary intervention in an all-comer population 被引量:4
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作者 Madeleine Eickhoff Stefanie Schupke +11 位作者 Alexander Khandoga Julia Fabian Moritz Baquet David Jochheim David Grundmann Manuela Thienel Axel Bauer Hans Theiss Stefan Brunner Jorg Hausleiter Steffen Massberg Julinda Mehilli 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2018年第9期559-566,共8页
Background The Synergy between Percutaneous Coronary Intervention with TAXUS and Cardiac Surgery (SYNTAX)-score is a validated tool for risk stratification and revascularization strategy selection in patients with c... Background The Synergy between Percutaneous Coronary Intervention with TAXUS and Cardiac Surgery (SYNTAX)-score is a validated tool for risk stratification and revascularization strategy selection in patients with complex coronary artery disease. The aim of this study was to analyse its age-related prognostic value. Methods SYNTAX-score was calculated in 1331 all-comer patients undergoing percutaneous coronary intervention (PCI): 463 patients ≥ 75 years and 868 patients 〈 75 years. Outcomes of interest were all-cause mortality at one and two years. Results A significant interaction of age and SYNTAX-score for mortality was observed at two-year (Pinteraction= 0.019) but not at one-year follow-up (Pinteraction= 0.594). In multivariable analysis, SYNTAX-score independently predicted 1-year mortality in both age groups (〈 75 years, hazard ratio (HR): 1.43, 95% confidence intervals (CI): 1.03-2.00, P = 0.034; and 〉 75 years, HR: 1.37, 95% CI: 1.01-1.85, P = 0.042), but only two-year mortality among younger patients (〈 75 years, HR: 1.33, 95% CI: 1.01-1.76, P = 0.041; and ≥ 75 years, HR: 1.11, 95% CI: 0.87-1.41, P = 0.394). SYNTAX-score tertiles were useful to stratify 1-year mortality in both, patients 〈 75 years (SYNTAX-score 〈 9, 3.8%; 9-20, 5.3%; 〉 20, 10.3%; P = 0.004) and 〉 75 years (SYNTAX-score 〈 11, 5.7%; 11-22.5, 16.1%; 〉 22.5, 18.7%; P = 0.003), but two-year mortality only among patients 〈 75 years (SYNTAX-score 〈 9, 6.5%; 9-20, 7.6%; ≥ 20, 15%; P 〈 0.001) and not among ≥ 75 years old patients (SYNTAX-score 〈 11, 19.4%; 11-22.5, 26.3%; _〉 22.5, 27.9%; P = 0.138). Conclusions Age modi- fies the impact of the SYNTAX-score on longer-term mortality after PCI. Among patients 〈 75 years, the SYNTAX-score independently predicts the risk of death at one and two years after PCI, while among patients 〉 75 years its predictive role is limited to the first year after PCI. Further studies are needed to evaluate the value of SYNTAX-score for selecting the most appropriate revascularization strategy among elderly patients. 展开更多
关键词 Age MORTALITY Percutaneous coronary intervention Syntax-score The elderly
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