On the basis of extensive literature search, the species, ingredients, pharmacology, clinical applications, ecological value and cultivation techniques of Scirpus tabemaemontani Gmel have been reviewed, to provide sci...On the basis of extensive literature search, the species, ingredients, pharmacology, clinical applications, ecological value and cultivation techniques of Scirpus tabemaemontani Gmel have been reviewed, to provide scientific data for further research & development.展开更多
Researches on pharmacological action and drug development of Periplane- ta americana have demonstrated that it has wide medicinal value, low side effects and rich resources, having good application prospects in medici...Researches on pharmacological action and drug development of Periplane- ta americana have demonstrated that it has wide medicinal value, low side effects and rich resources, having good application prospects in medicine field. This article reviewed the researches on pharmacological action and clinical application of Periplaneta americana in order to provide references for the further research and devel- opment of Periplaneta americana medicines.展开更多
In order to explore the application effect of Yezhiyuan in early hybrid rice,Liangliangyou No.211 and Lingliangyou No.268 were tested in a teaching base in Hunan Agricultural University and Xidu Town, Hengyang County,...In order to explore the application effect of Yezhiyuan in early hybrid rice,Liangliangyou No.211 and Lingliangyou No.268 were tested in a teaching base in Hunan Agricultural University and Xidu Town, Hengyang County, with Yezhiyuan.The test results showed that the application of photosynthesis synergist in later tillering stage would increase the content of chlorophyll of functional leaf and photosynthetic rate, reduce transpiration rate and enhance yield per unit area. With Yezhiyuan applied, both of photosynthetic rate and chlorophyll content kept higher compared with control group in two experimental sites, and practical yield in Hunan Agricultural University grew 8.54% higher compared with control group, and 10.67%in Hengyang.展开更多
The plant immunity inducer, amino-oligosaccharin, has remarkable effects in disease resistance, cold tolerance, growth promotion, yield increase and quality improvement. This paper introduced the action mechanism of a...The plant immunity inducer, amino-oligosaccharin, has remarkable effects in disease resistance, cold tolerance, growth promotion, yield increase and quality improvement. This paper introduced the action mechanism of amino-oligosaccharin, its main application effects on crops and application techniques. In 2013-2014, ex- periments were conducted on a variety of crops at multiple locations by Xinjiang Corps as well as popularization and application in 2013-2014, and it was shown by the popularization and application that the application of amino-oligosaccharin could promote plant growth, reduce the incidence of crop diseases and improve crop yield and product quality.展开更多
At present,the methods of analyzing the stability of slope under earthquake are not accurate and reasonable because of some limitations. Based on the real dynamic tensile-shear failure mechanism of slope,the paper pro...At present,the methods of analyzing the stability of slope under earthquake are not accurate and reasonable because of some limitations. Based on the real dynamic tensile-shear failure mechanism of slope,the paper proposes dynamic analysis of strength reduction FEM (finite element method) and takes the reduction of shear strength parameters and tensile strength parameters into consideration. And it comprehensively takes the transfixion of the failure surface,the non-convergence of calculation and mutation of displacement as the criterion of dynamic instability and failure of the slope. The strength reduction factor under limit state is regarded as the dynamic safety factor of the slope under earthquake effect and its advantages are introduced. Finally,the method is applied in the seismic design of anchors supporting and anti-slide pile supporting of the slope. Calculation examples show that the application of dynamic analysis of strength reduction is feasible in the seismic design of slope engineering,which can consider dynamic interaction of supporting structure and rock-soil mass. Owing to its preciseness and great advantages,it is a new method in the seismic design of slope supporting.展开更多
SO4^2-/TiO2-MoO3, a novel solid superacid, has been prepared and its catalytic activity at different synthetic conditions was examined with esterification of n-butanoic acid and n-butyl alcohol as probing reaction.The...SO4^2-/TiO2-MoO3, a novel solid superacid, has been prepared and its catalytic activity at different synthetic conditions was examined with esterification of n-butanoic acid and n-butyl alcohol as probing reaction.The optimum conditions were also found, that is, the mass ratio of MoO3 used in the compound is 25%, the calcination temperature 450℃, and the soaked consistency of H2SO4 is 0.5mol.L^-1. Then it was applied in the catalytic synthesis of six similar important ketals and acetals as catalyst and revealed high catalytic activity. Under the condition that the molar ratio of aldehyde/ketone to glycol was 1:1.5, the mass ratio of the catalyst to the reactants was 0.5% and the reaction time 1.0 h, the yield of ketals and acetals reached up to 63.2%. The catalyst can be easily recovered and reused.展开更多
Developing classes of Ag@C composites stand out for their one of a kind structure and novel physicochemical properties in later a long time.This review explores the current state-of-the-art progress in the preparation...Developing classes of Ag@C composites stand out for their one of a kind structure and novel physicochemical properties in later a long time.This review explores the current state-of-the-art progress in the preparation methods and the novel properties of Ag@C composites.We provide a definition of the stability of Ag@C composites,and propose strategies to improve the stability.Based on the later inquire,a summary and outlook toward the synthesis and applications of Ag@C composites are presented,aiming to accelerate the exploration of Ag@C composites and further stimulate the applications in various fields.展开更多
A synthetic technology for the production of methyl-ethyl-ketone (MEK) is introduced, which makes use of butylene catalytic hydration to produce secondary butanol (SBA) and this is followed by dehydrogenation of SBA. ...A synthetic technology for the production of methyl-ethyl-ketone (MEK) is introduced, which makes use of butylene catalytic hydration to produce secondary butanol (SBA) and this is followed by dehydrogenation of SBA. By optimizing the operating conditions of a commercial unit, the running results showed that the recom-mended process was successful and that the catalysts had high activity, good selectivity, and long lifespan, which ensured long-term running in commercial units.展开更多
Graphene(GR),a single‐layer carbon sheet with a hexagonal packed lattice structure,has displayed attractive potential and demonstrably become the research focus in artificial photocatalysis due to its enchanting prop...Graphene(GR),a single‐layer carbon sheet with a hexagonal packed lattice structure,has displayed attractive potential and demonstrably become the research focus in artificial photocatalysis due to its enchanting properties in enhancing light absorption,electron transfer dynamics,and surface reactions.Currently,numerous efforts have shown that the properties of GR,which are closely correlated to the photocatalytic performance of GR‐based composites are significantly affected by the synthesis methods.Herein,we first introduce the optimization strategies of GR‐based hybrids and then elaborate the synthesis of GR‐based composite photocatalysts oriented by manifold roles of GR in photoredox catalysis,containing photoelectron mediator and acceptor,improving adsorption capacity,regulating light absorption range and intensity,as well as macromolecular photosensitizer.Beyond that,a brief outlook on the challenges in this burgeoning research field and potential evolution strategies for enhancing the photoactivity of GR‐based hybrids is presented and we anticipate that this review could provide some enlightenments for the rational construction and application of multifunctional GR‐based composite photocatalysts.展开更多
The traditional stability analysis method of geogrid reinforced slopes does not consider the effect of lateral swelling,so it is not applicable to reinforced expansive soil slopes.This paper reports a new stability an...The traditional stability analysis method of geogrid reinforced slopes does not consider the effect of lateral swelling,so it is not applicable to reinforced expansive soil slopes.This paper reports a new stability analysis method for geogrid reinforced expansive soil slopes.The additional pullout force of the free zone due to the lateral swelling and the anti-pullout safety factor of each geogrid layer were obtained by ensuring the overall stability of the reinforced slope.The optimum design was carried out to treat an expansive soil cut slope in Hubei Province,China,by changing the spacing and length of geogrid reinforcement.Calculation results show that the additional pullout force caused by lateral swelling has a great influence on the anti-pullout stability of geogrids,and the local stability of the reinforced slope will be overestimated if the swelling effect of soil in the free zone is not considered.展开更多
A computer code based on the double-body potential flow model and the classic source panel method has been developed to study various problems of hydrodynamic interaction between ships and other objects with solid bou...A computer code based on the double-body potential flow model and the classic source panel method has been developed to study various problems of hydrodynamic interaction between ships and other objects with solid boundaries including the seabed. A peculiarity of the proposed implementation is the application of the so-called "moving-patch" method for simulating steady boundaries of large extensions. The method is based on an assumption that at any moment just the part of the boundary ("moving patch") which lies close to the interacting ship is significant for the near-field interaction. For a specific case of the fiat bottom, comparative computations were performed to determine optimal dimensions of the patch and of the constituting panels based on the trade-off between acceptable accuracy and reasonable efficiency. The method was applied to estimate the sway force on a ship hull moving obliquely across a dredged channel. The method was validated for a case of ship-to-ship interaction when tank data were available. This study also contains a description of a newly developed spline approximation algorithm necessary for creating consistent discretizations of ship hulls with various degrees of refinement.展开更多
AIM:To analyze the pathogenetic role and potential clinical usefulness of the epidermal growth factor receptor(EGFR)and the human epidermal growth factor receptor 2(HER2)in patients with advanced biliary tract cancer(...AIM:To analyze the pathogenetic role and potential clinical usefulness of the epidermal growth factor receptor(EGFR)and the human epidermal growth factor receptor 2(HER2)in patients with advanced biliary tract cancer(BTC). METHODS:EGFR and HER2 expression was studied in biopsy samples from 124 patients(51%women; median age 64.8 years),with advanced BTC diagnosed between 1997 and 2004.Five micrometers sections of paraffin embedded tissue were examined by standard, FDA approved immunohistochemistry.Tumors with scores of 2+or 3+for HER2 expression on immunochemistry were additionally tested for HER2 gene amplification by fluorescence in situ hybridisation(FISH).RESULTS:34/124 patients(27.4%)had gallbladder cancer,47(37.9%)had intrahepatic BTC and 43(34.7%)had extrahepatic or perihilar BTC.EGFR expression was examined in a subset of 56 samples. EGFR expression was absent in 22/56 tumors(39.3%). Of the remaining samples expression was scored as 1+in 12(21.5%),2+in 13(23.2%)and 3+in 9(16%), respectively.HER2 expression was as follows:score 0 73/124(58.8%),score 1+27/124(21.8%),score 2+ 21/124(17%)and score 3+4/124(3.2%).HER2 gene amplification was present in 6/124,resulting in an overall amplification rate of 5%. CONCLUSION:Our data suggest that routine testing and therapeutic targeting of HER2 does not seem to be useful in patients with BTC,while targeting EGFR may be promising.展开更多
In the system of several interacting spins,geometric phases have been researched intensively.However,the studies are mainly focused on the adiabatic case (Berry phase),so it is necessary for us to study the non-adiaba...In the system of several interacting spins,geometric phases have been researched intensively.However,the studies are mainly focused on the adiabatic case (Berry phase),so it is necessary for us to study the non-adiabaticcounterpart (Aharonov and Anandan phase).In this paper,we analyze both the non-degenerate and degenerate geometricphase of Lipkin-Meskov-Glick type model,which has many application in Bose-Einstein condensates and entanglementtheory.Furthermore,in order to calculate degenerate geometric phases,the Floquet theorem and decomposition ofoperator are generalized.And the general formula is achieved.展开更多
Soil potassium (K) deficiency has been increasing over recent decades as a result of higher inputs of N and P fertilizers concomitant with lower inputs of K fertilizers in China; however, the effects of interactions...Soil potassium (K) deficiency has been increasing over recent decades as a result of higher inputs of N and P fertilizers concomitant with lower inputs of K fertilizers in China; however, the effects of interactions between N, P, and K of fertilizers on K status in soils have not been thoroughly investigated for optimizing N, P, and K fertilizer use efficiency. The influence of ammonium sulfate (AS), monocMcium phosphate (MCP), and potassium chloride application on K fractions in three typical soils of China was evaluated during 90-d laboratory soil incubation. The presence of AS significantly altered the distribution of native and added K in soils, while addition of MCP did not significantly affected K equilibrium in most cases. Addition of AS significantly increased water-soluble K (WSK), decreased exchangeable K (EK) in almost all the soils except the paddy soil that contained considerable amounts of 2:1 type clay minerals with K added, retarded the formation of fixed K in the soils with K added, and suppressed the release of fixed K in the three soils without K added. These interactions might be expected to influence the K availability to plants when the soil was fertilized with AS. To improve K fertilizer use efficiency, whether combined application of AS and K was to be recommended or avoided should depend on K status of the soil, soil properties, and cropping systems.展开更多
A new type of airtight wall with the combination of foamed concrete and pier support was designed in this study. Based on the theories and models related to the foamed concrete and blasting shock load, using the numer...A new type of airtight wall with the combination of foamed concrete and pier support was designed in this study. Based on the theories and models related to the foamed concrete and blasting shock load, using the numerical analysis method, this study obtains the new material's mechanical and destruction laws through analyzing its reaction to different conditions of load (mining and shock waves), airtight wall thickness (1.2, 1.5, 1.8, 2.1 m) and steel pipe diameters (400, 450, 500 and 600 mm). The results show that: ①foamed concrete can have very good suspension, and the pier column support is the main carrier of roof pressure; ② the damaged area of foamed concrete decreases as the foamed concrete thickness increases. Under impact loading, the thickness of the foamed concrete wall plays a more obvious role in retaining its integrity; ③under the same mining pressure, the damage area increases as the steel pipe diameter increases; ④ with additional mining stress increase, under whether static load or impact load, the stress on the foamed concrete and steel pipe will also increase gradually, therefore the actual airtight wall design will need to be based on specific circumstances in steel stress.展开更多
Recombinant Escherichia coli pUDP,which overexpressed uridine phosphorylase(UPase),was constructed.0.5 mmol·L 1lactose had a similar induction effect as the commonly used inducer IPTG during 2.5-5.5 h of cell g...Recombinant Escherichia coli pUDP,which overexpressed uridine phosphorylase(UPase),was constructed.0.5 mmol·L 1lactose had a similar induction effect as the commonly used inducer IPTG during 2.5-5.5 h of cell growth.The lactose-induced UPase was stable at 50°C.Wet cells of pUDP was used as catalyst to biosynthesize 5-fluorouridine from 30 mmol·L 1uridine and 5-fluorouracil in phosphate buffer(pH 7.0)catalyzed at 50°C for 1.5 h and the yield of 5-fluorouridine was higher than 68%.Under the optimum reaction conditions for production of 5-fluorouridine,5-methyluridine and azauridine were synthesized from uridine by pUDP,the yield was 61.7%and 47.2%respectively.Deoxynucleosides were also synthesized by pUDP,but the yield was only about 20%.展开更多
Considering the interaction between the electromagnetic field and matter field, a concise method is used to calculate the ground-state energy of the interacting system. With the assumption of squeezed-like state, a ne...Considering the interaction between the electromagnetic field and matter field, a concise method is used to calculate the ground-state energy of the interacting system. With the assumption of squeezed-like state, a new vacuum state is obtained for the inte racting system. The energy of the new vacuum state is obviously lower than that of unperturbed vacu um state. Based on the new vacuum state, the correction to the Casimir force is obtained. The r esult shows that the contribution of the interaction is a repulsive one and the Casimir effect is attributed to both electromagnetic field and matter field. On the basis of the obtained results, th e recent experimental data can be explained reasonably.展开更多
With the increasing popularity of cloud computing, there is an increased de mand for cloud resources in cloud. It has be come even more urgent to find solutions to improve resource utilization. From the per spective o...With the increasing popularity of cloud computing, there is an increased de mand for cloud resources in cloud. It has be come even more urgent to find solutions to improve resource utilization. From the per spective of a cloud consumer, a cloud applica tion processes a large information flow in volving user actions that access resources, but little work has so far been devoted to research from the perspective of the interaction be tween the user and the cloud application. In this paper, we analyze the interaction in detail, and propose a general mathematical interac tion model to formulate the challenge pertain ing to storage resource allocation as an opti mization problem, focusing on minimizing both the user's cost and server's consumption. A potential response mechanism is then de signed based on the interaction model. Fur thermore, the proposed model is used to ex plore strategies when multiple users access the same file simultaneously. Additionally, an improved queuing system, namely M/ G~ oo queue with standby, is introduced. Finally, an evaluation is presented to verify the interac- tion model.展开更多
文摘On the basis of extensive literature search, the species, ingredients, pharmacology, clinical applications, ecological value and cultivation techniques of Scirpus tabemaemontani Gmel have been reviewed, to provide scientific data for further research & development.
基金Supported by the National Natural Science Foundation of China(30560181)the Major Project of Yunnan Province(2008IF012)~~
文摘Researches on pharmacological action and drug development of Periplane- ta americana have demonstrated that it has wide medicinal value, low side effects and rich resources, having good application prospects in medicine field. This article reviewed the researches on pharmacological action and clinical application of Periplaneta americana in order to provide references for the further research and devel- opment of Periplaneta americana medicines.
基金Supported by National Key Technology R&D Program(2011BAD16B012012BAD04B10,2013BAD07B11)~~
文摘In order to explore the application effect of Yezhiyuan in early hybrid rice,Liangliangyou No.211 and Lingliangyou No.268 were tested in a teaching base in Hunan Agricultural University and Xidu Town, Hengyang County, with Yezhiyuan.The test results showed that the application of photosynthesis synergist in later tillering stage would increase the content of chlorophyll of functional leaf and photosynthetic rate, reduce transpiration rate and enhance yield per unit area. With Yezhiyuan applied, both of photosynthetic rate and chlorophyll content kept higher compared with control group in two experimental sites, and practical yield in Hunan Agricultural University grew 8.54% higher compared with control group, and 10.67%in Hengyang.
文摘The plant immunity inducer, amino-oligosaccharin, has remarkable effects in disease resistance, cold tolerance, growth promotion, yield increase and quality improvement. This paper introduced the action mechanism of amino-oligosaccharin, its main application effects on crops and application techniques. In 2013-2014, ex- periments were conducted on a variety of crops at multiple locations by Xinjiang Corps as well as popularization and application in 2013-2014, and it was shown by the popularization and application that the application of amino-oligosaccharin could promote plant growth, reduce the incidence of crop diseases and improve crop yield and product quality.
基金Financial Support by Special Research fund of State Key Laboratory of Geohazard Prevention and Geoenvironment Protection (Chengdu University of Technology) (GZ2009-14)Special Research fund of Minis-try of Education Key Laboratory of Urban Security and Disaster Engineering
文摘At present,the methods of analyzing the stability of slope under earthquake are not accurate and reasonable because of some limitations. Based on the real dynamic tensile-shear failure mechanism of slope,the paper proposes dynamic analysis of strength reduction FEM (finite element method) and takes the reduction of shear strength parameters and tensile strength parameters into consideration. And it comprehensively takes the transfixion of the failure surface,the non-convergence of calculation and mutation of displacement as the criterion of dynamic instability and failure of the slope. The strength reduction factor under limit state is regarded as the dynamic safety factor of the slope under earthquake effect and its advantages are introduced. Finally,the method is applied in the seismic design of anchors supporting and anti-slide pile supporting of the slope. Calculation examples show that the application of dynamic analysis of strength reduction is feasible in the seismic design of slope engineering,which can consider dynamic interaction of supporting structure and rock-soil mass. Owing to its preciseness and great advantages,it is a new method in the seismic design of slope supporting.
文摘SO4^2-/TiO2-MoO3, a novel solid superacid, has been prepared and its catalytic activity at different synthetic conditions was examined with esterification of n-butanoic acid and n-butyl alcohol as probing reaction.The optimum conditions were also found, that is, the mass ratio of MoO3 used in the compound is 25%, the calcination temperature 450℃, and the soaked consistency of H2SO4 is 0.5mol.L^-1. Then it was applied in the catalytic synthesis of six similar important ketals and acetals as catalyst and revealed high catalytic activity. Under the condition that the molar ratio of aldehyde/ketone to glycol was 1:1.5, the mass ratio of the catalyst to the reactants was 0.5% and the reaction time 1.0 h, the yield of ketals and acetals reached up to 63.2%. The catalyst can be easily recovered and reused.
基金Projects(2018YFC1802204,2020YFC1909200)supported by the National Key R&D Program of China。
文摘Developing classes of Ag@C composites stand out for their one of a kind structure and novel physicochemical properties in later a long time.This review explores the current state-of-the-art progress in the preparation methods and the novel properties of Ag@C composites.We provide a definition of the stability of Ag@C composites,and propose strategies to improve the stability.Based on the later inquire,a summary and outlook toward the synthesis and applications of Ag@C composites are presented,aiming to accelerate the exploration of Ag@C composites and further stimulate the applications in various fields.
文摘A synthetic technology for the production of methyl-ethyl-ketone (MEK) is introduced, which makes use of butylene catalytic hydration to produce secondary butanol (SBA) and this is followed by dehydrogenation of SBA. By optimizing the operating conditions of a commercial unit, the running results showed that the recom-mended process was successful and that the catalysts had high activity, good selectivity, and long lifespan, which ensured long-term running in commercial units.
文摘Graphene(GR),a single‐layer carbon sheet with a hexagonal packed lattice structure,has displayed attractive potential and demonstrably become the research focus in artificial photocatalysis due to its enchanting properties in enhancing light absorption,electron transfer dynamics,and surface reactions.Currently,numerous efforts have shown that the properties of GR,which are closely correlated to the photocatalytic performance of GR‐based composites are significantly affected by the synthesis methods.Herein,we first introduce the optimization strategies of GR‐based hybrids and then elaborate the synthesis of GR‐based composite photocatalysts oriented by manifold roles of GR in photoredox catalysis,containing photoelectron mediator and acceptor,improving adsorption capacity,regulating light absorption range and intensity,as well as macromolecular photosensitizer.Beyond that,a brief outlook on the challenges in this burgeoning research field and potential evolution strategies for enhancing the photoactivity of GR‐based hybrids is presented and we anticipate that this review could provide some enlightenments for the rational construction and application of multifunctional GR‐based composite photocatalysts.
基金Project(51978085)supported by the National Natural Science Foundation of ChinaProject(201808430102)supported by the China Scholarship Council+1 种基金Project(JTG-201507)supported by the Highway Industry Standard Compilation Project of Ministry of Transportation,ChinaProject(kfj180102)supported by the Open Fund of Changsha University of Science&Technology,China。
文摘The traditional stability analysis method of geogrid reinforced slopes does not consider the effect of lateral swelling,so it is not applicable to reinforced expansive soil slopes.This paper reports a new stability analysis method for geogrid reinforced expansive soil slopes.The additional pullout force of the free zone due to the lateral swelling and the anti-pullout safety factor of each geogrid layer were obtained by ensuring the overall stability of the reinforced slope.The optimum design was carried out to treat an expansive soil cut slope in Hubei Province,China,by changing the spacing and length of geogrid reinforcement.Calculation results show that the additional pullout force caused by lateral swelling has a great influence on the anti-pullout stability of geogrids,and the local stability of the reinforced slope will be overestimated if the swelling effect of soil in the free zone is not considered.
基金Supported by the Portuguese Foundation for Science and Technology under Grant No.PTDC/ECM/100686/2008
文摘A computer code based on the double-body potential flow model and the classic source panel method has been developed to study various problems of hydrodynamic interaction between ships and other objects with solid boundaries including the seabed. A peculiarity of the proposed implementation is the application of the so-called "moving-patch" method for simulating steady boundaries of large extensions. The method is based on an assumption that at any moment just the part of the boundary ("moving patch") which lies close to the interacting ship is significant for the near-field interaction. For a specific case of the fiat bottom, comparative computations were performed to determine optimal dimensions of the patch and of the constituting panels based on the trade-off between acceptable accuracy and reasonable efficiency. The method was applied to estimate the sway force on a ship hull moving obliquely across a dredged channel. The method was validated for a case of ship-to-ship interaction when tank data were available. This study also contains a description of a newly developed spline approximation algorithm necessary for creating consistent discretizations of ship hulls with various degrees of refinement.
文摘AIM:To analyze the pathogenetic role and potential clinical usefulness of the epidermal growth factor receptor(EGFR)and the human epidermal growth factor receptor 2(HER2)in patients with advanced biliary tract cancer(BTC). METHODS:EGFR and HER2 expression was studied in biopsy samples from 124 patients(51%women; median age 64.8 years),with advanced BTC diagnosed between 1997 and 2004.Five micrometers sections of paraffin embedded tissue were examined by standard, FDA approved immunohistochemistry.Tumors with scores of 2+or 3+for HER2 expression on immunochemistry were additionally tested for HER2 gene amplification by fluorescence in situ hybridisation(FISH).RESULTS:34/124 patients(27.4%)had gallbladder cancer,47(37.9%)had intrahepatic BTC and 43(34.7%)had extrahepatic or perihilar BTC.EGFR expression was examined in a subset of 56 samples. EGFR expression was absent in 22/56 tumors(39.3%). Of the remaining samples expression was scored as 1+in 12(21.5%),2+in 13(23.2%)and 3+in 9(16%), respectively.HER2 expression was as follows:score 0 73/124(58.8%),score 1+27/124(21.8%),score 2+ 21/124(17%)and score 3+4/124(3.2%).HER2 gene amplification was present in 6/124,resulting in an overall amplification rate of 5%. CONCLUSION:Our data suggest that routine testing and therapeutic targeting of HER2 does not seem to be useful in patients with BTC,while targeting EGFR may be promising.
基金Supported by the National Natural Science Foundation of China under Grant Nos. 10605013 and 10975075the Fundamental Research Funds for the Central Universities
文摘In the system of several interacting spins,geometric phases have been researched intensively.However,the studies are mainly focused on the adiabatic case (Berry phase),so it is necessary for us to study the non-adiabaticcounterpart (Aharonov and Anandan phase).In this paper,we analyze both the non-degenerate and degenerate geometricphase of Lipkin-Meskov-Glick type model,which has many application in Bose-Einstein condensates and entanglementtheory.Furthermore,in order to calculate degenerate geometric phases,the Floquet theorem and decomposition ofoperator are generalized.And the general formula is achieved.
基金Supported by the Knowledge Innovative Program of the Chinese Academy of Sciences (No.KSCX2-YW-N-002)the National Key Basic Research Program of China(No.2007CB109301)+1 种基金the National Natural Science Foundation of China(No.40971176)the International Potash Institute China Project
文摘Soil potassium (K) deficiency has been increasing over recent decades as a result of higher inputs of N and P fertilizers concomitant with lower inputs of K fertilizers in China; however, the effects of interactions between N, P, and K of fertilizers on K status in soils have not been thoroughly investigated for optimizing N, P, and K fertilizer use efficiency. The influence of ammonium sulfate (AS), monocMcium phosphate (MCP), and potassium chloride application on K fractions in three typical soils of China was evaluated during 90-d laboratory soil incubation. The presence of AS significantly altered the distribution of native and added K in soils, while addition of MCP did not significantly affected K equilibrium in most cases. Addition of AS significantly increased water-soluble K (WSK), decreased exchangeable K (EK) in almost all the soils except the paddy soil that contained considerable amounts of 2:1 type clay minerals with K added, retarded the formation of fixed K in the soils with K added, and suppressed the release of fixed K in the three soils without K added. These interactions might be expected to influence the K availability to plants when the soil was fertilized with AS. To improve K fertilizer use efficiency, whether combined application of AS and K was to be recommended or avoided should depend on K status of the soil, soil properties, and cropping systems.
文摘A new type of airtight wall with the combination of foamed concrete and pier support was designed in this study. Based on the theories and models related to the foamed concrete and blasting shock load, using the numerical analysis method, this study obtains the new material's mechanical and destruction laws through analyzing its reaction to different conditions of load (mining and shock waves), airtight wall thickness (1.2, 1.5, 1.8, 2.1 m) and steel pipe diameters (400, 450, 500 and 600 mm). The results show that: ①foamed concrete can have very good suspension, and the pier column support is the main carrier of roof pressure; ② the damaged area of foamed concrete decreases as the foamed concrete thickness increases. Under impact loading, the thickness of the foamed concrete wall plays a more obvious role in retaining its integrity; ③under the same mining pressure, the damage area increases as the steel pipe diameter increases; ④ with additional mining stress increase, under whether static load or impact load, the stress on the foamed concrete and steel pipe will also increase gradually, therefore the actual airtight wall design will need to be based on specific circumstances in steel stress.
基金Supported by"Production,Education&Research"item of Shanghai Baoshan(08-H-4)
文摘Recombinant Escherichia coli pUDP,which overexpressed uridine phosphorylase(UPase),was constructed.0.5 mmol·L 1lactose had a similar induction effect as the commonly used inducer IPTG during 2.5-5.5 h of cell growth.The lactose-induced UPase was stable at 50°C.Wet cells of pUDP was used as catalyst to biosynthesize 5-fluorouridine from 30 mmol·L 1uridine and 5-fluorouracil in phosphate buffer(pH 7.0)catalyzed at 50°C for 1.5 h and the yield of 5-fluorouridine was higher than 68%.Under the optimum reaction conditions for production of 5-fluorouridine,5-methyluridine and azauridine were synthesized from uridine by pUDP,the yield was 61.7%and 47.2%respectively.Deoxynucleosides were also synthesized by pUDP,but the yield was only about 20%.
文摘Considering the interaction between the electromagnetic field and matter field, a concise method is used to calculate the ground-state energy of the interacting system. With the assumption of squeezed-like state, a new vacuum state is obtained for the inte racting system. The energy of the new vacuum state is obviously lower than that of unperturbed vacu um state. Based on the new vacuum state, the correction to the Casimir force is obtained. The r esult shows that the contribution of the interaction is a repulsive one and the Casimir effect is attributed to both electromagnetic field and matter field. On the basis of the obtained results, th e recent experimental data can be explained reasonably.
基金supported in part by the National Natural Science Foundation of China under Grant No. 61271199the Fundamental Research Funds in Beijing Jiaotong University under Grant No. W11JB00630
文摘With the increasing popularity of cloud computing, there is an increased de mand for cloud resources in cloud. It has be come even more urgent to find solutions to improve resource utilization. From the per spective of a cloud consumer, a cloud applica tion processes a large information flow in volving user actions that access resources, but little work has so far been devoted to research from the perspective of the interaction be tween the user and the cloud application. In this paper, we analyze the interaction in detail, and propose a general mathematical interac tion model to formulate the challenge pertain ing to storage resource allocation as an opti mization problem, focusing on minimizing both the user's cost and server's consumption. A potential response mechanism is then de signed based on the interaction model. Fur thermore, the proposed model is used to ex plore strategies when multiple users access the same file simultaneously. Additionally, an improved queuing system, namely M/ G~ oo queue with standby, is introduced. Finally, an evaluation is presented to verify the interac- tion model.