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新型压电激励器作用力模拟技术研究
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作者 雷鸣 李阳 《航空工程进展》 CSCD 2017年第4期431-437,共7页
研究轻型结构、直升机旋翼结构和复合材料结构等的颤振飞行试验激励问题具有重要意义。提出以弯矩模拟压电粗纤维复合材料(MFC)激励器的作用力,从而解决MFC仿真建模问题。首先借助机翼有限元模型,建立带有压电激励器的机翼结构动力学仿... 研究轻型结构、直升机旋翼结构和复合材料结构等的颤振飞行试验激励问题具有重要意义。提出以弯矩模拟压电粗纤维复合材料(MFC)激励器的作用力,从而解决MFC仿真建模问题。首先借助机翼有限元模型,建立带有压电激励器的机翼结构动力学仿真模型;然后以压电激励器地面激励试验结果为基础,通过修正仿真模型中压电作用弯矩的大小,实现仿真试验结果与地面试验结果的拟合,最终得出非线性压电激励器作用力;最后通过另一组地面试验数据验证了该作用力的大小,并将该作用力模拟技术应用于不同试验中。本文的研究结果可为后续以该激励器作为激励作动器或控制作动器的试验提供有益参考。 展开更多
关键词 压电激励器MFC 结构动力学建模 仿真试验 作用力拟合 技术应用
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Molecular Mechanism of the Early Stage of Amyloidogenic Hexapeptides(NFGAIL) Aggregation
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作者 施碧云 周波 +2 位作者 蔡卓伟 修鹏 杨再兴 《Communications in Theoretical Physics》 SCIE CAS CSCD 2013年第10期515-520,共6页
Peptides/proteins aggregation can give rise to pathological conditions of many human diseases.Small partially ordered oligomers formed in the early stage of aggregation,rather than mature fibrils,are thought to be the... Peptides/proteins aggregation can give rise to pathological conditions of many human diseases.Small partially ordered oligomers formed in the early stage of aggregation,rather than mature fibrils,are thought to be the main toxicity agent for the living cell.Thus,understanding the pathway and the underlying physical mechanism in the early stage of aggregation is very important for prevention and treatment of these protein functional diseases.Herein we use all-atom molecular dynamics simulations to study the aggregation of four NFGAIL hexapeptides(NFGAIL peptide is a core segment of human islet amyloid polypeptide and exhibits similar aggregation kinetics as the full-length polypeptide).We observe that the peptide monomers in water mainly adopt non-structural coil configurations;the four peptides which are randomly placed in water aggregate spontaneously to partially ordered oligomer(β-sheets)through dimerization or trimerization,with the dimerization predominated.Both parallel and anti-parallelβ-sheets are observed.The hydrophobic interactions drive the initial peptides associations,and the subsequent conformational fluctuations promote the formation of more hydrogen bonds between the dangling hydrogen sites in the main chains of peptides. 展开更多
关键词 peptides aggregation dimerization and trimerization hydrophobic interactions molecular dy-namics simulations
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