A new kind of region pair grey difference classifier was proposed. The regions in pairs associated to form a feature were not necessarily directly-connected, but were selected dedicatedly to the grey transition betwee...A new kind of region pair grey difference classifier was proposed. The regions in pairs associated to form a feature were not necessarily directly-connected, but were selected dedicatedly to the grey transition between regions coinciding with the face pattern structure. Fifteen brighter and darker region pairs were chosen to form the region pair grey difference features with high discriminant capabilities. Instead of using both false acceptance rate and false rejection rate, the mutual information was used as a unified metric for evaluating the classifying performance. The parameters of specified positions, areas and grey difference bias for each single region pair feature were selected by an optimization processing aiming at maximizing the mutual information between the region pair feature and classifying distribution, respectively. An additional region-based feature depicting the correlation between global region grey intensity patterns was also proposed. Compared with the result of Viola-like approach using over 2 000 features, the proposed approach can achieve similar error rates with only 16 features and 1/6 implementation time on controlled illumination images.展开更多
The combination of Morgenstern-Price Method (MPM) with Response Surface Method (RSM) improves the eonventional RSM by replacing Finite-Element Method (FEM) with MPM, which is a type of reliability analysis metho...The combination of Morgenstern-Price Method (MPM) with Response Surface Method (RSM) improves the eonventional RSM by replacing Finite-Element Method (FEM) with MPM, which is a type of reliability analysis method-RSM based on MPM, and makes the computing process simpler. The stability of the slope was re-evaluated by use of Monte Carlo method (MCM) and the result contrasted with the fore is the conclusion. The reliability analysis of the artificial slope in Donggang Power Station was carried on, and obtained the reliable charaeteristics, which provided basis for the project.展开更多
Gradual shift has been observed lately of dam safety procedures from the conventional technical based towards a wider scope of risk management procedure based on risk analysis. The new approach considers the likelihoo...Gradual shift has been observed lately of dam safety procedures from the conventional technical based towards a wider scope of risk management procedure based on risk analysis. The new approach considers the likelihood level of occurrence of a multitude of hazards and the magnitude of the resulting possible consequences in case of failure using rational cause and effect arguments. Most dam owners are shifting towards the use of the new risk based procedures; and even governments themselves are moving towards formalizing the new trend. Legislations in the United States were promulgated [1] after serious dam failures and the adoption of stringent levels of scrutiny led such federal dam owners to pioneer in this field and in developing the concepts and methods required. The comer stone in risk analysis is the definition of the potential modes that may lead to failure and assessment of the likelihood levels of their occurrence and possible category of the consequences which, after thorough evaluation, will shape the decision making. This type of analysis was applied to Mosul Dam as a case study and resulted in definite recommendations.展开更多
Municipalities are autonomous economic and administrative entities, with common actions and responsibilities. Moreover, all Municipalities are quite different considering specific characteristics, such as geographic, ...Municipalities are autonomous economic and administrative entities, with common actions and responsibilities. Moreover, all Municipalities are quite different considering specific characteristics, such as geographic, demographic, and economic. The aim of this research is to separate the entire sample of Municipalities in Greece into categories, based on the effectiveness of financial management and financial performance into effective and ineffective ones. For the separation of the sample into groups, cluster analysis was preferred. For this reason, three variables were used: the lending capacity of the Municipality, flexibility in making non-investment costs, and flexibility in investment spending. These three variables were considered to be the key dimensions of effectiveness in financial management and therefore their use, representatively describes the effectiveness of Greek Municipalities. Thus, this paper presents the literature review of the financial effectiveness of Municipalities and the methodology of an empirical research through structured questionnaire that was sent to the entire population of Greek Municipalities, characterized in this way with considerable heterogeneity. In this way, it investigates the views of Mayors in the two categories of Municipalities (effective and non effective financial management and financial performance) as regards: (a) the biggest problems faced by the citizens in their Municipality, and (b) the biggest personnel problems faced by their Municipality. Concluding, the prioritization of both problems seems to be the same for both groups of Municipalities. The frequency of responses differs slightly and differences are not so large that financial performance can be considered to affect respondents' opinions.展开更多
The emotional factors play an important role in the process of language learning. Exploration of the emotional problems in the process of English learning can promote the emotional communication between teachers and s...The emotional factors play an important role in the process of language learning. Exploration of the emotional problems in the process of English learning can promote the emotional communication between teachers and students. The organic combination of the two aspects of cognitive and emotional can help to finish the promotion of cognitive and education with emotion. People abroad have achieved many results about the research, while further research in domestic is still rare. This paper mainly analyzes the main emotional problems influencing the English leaming, clarifies the importance of using emotional strategy in English learning, points out the way of improving learning effect by affective strategies, thus to guide the students form the corresponding emotion strategy, effectively use in English learning, and improve the English learning.展开更多
Proper phylogenetic reconstruction is crucial for understanding many evolutionary phenomena. In spite of the great success of molecular phylogenetics, DNA signal still may be limited by some intrinsic constraints such...Proper phylogenetic reconstruction is crucial for understanding many evolutionary phenomena. In spite of the great success of molecular phylogenetics, DNA signal still may be limited by some intrinsic constraints such as codon usage bias. The phylogenetic relationships between the five species subgroups of the Drosophila saltans group are a good example of conflicting molecular phylogenies drawn from different genes due to an ancestral substitutional shift. Here, forty morphological characters were analyzed using the same set of species used in previous molecular studies, with at least a single representative of each subgroup. The cladistic analysis was in disagreement with most of the previous hypotheses in placing the sturtevanti subgroup as an early branch, whereas the four remaining subgroups form a well supported clade that can be further subdivided into two sister clades: one containing the cordata and the elliptica subgroups, whereas the second includes the parasaltans and the saltans subgroups. The molecular evolution (codon usage bias) of the saltans group were revised in light of the present finding. The analysis highlights the important role of morphology in phylogeny reconstruction and in understanding molecular evolutionary phenomena.展开更多
In order to address spectrum resource scarcity in traditional cellular networks,television(TV)white space is considered as a potential solution to offload a portion of network traffic and enlarge network capacity.This...In order to address spectrum resource scarcity in traditional cellular networks,television(TV)white space is considered as a potential solution to offload a portion of network traffic and enlarge network capacity.This paper describes a cognitive cellular network which allocates low geometry users to the TV white space based on a proportional fair criterion.An uplink user allocation scheme is proposed and the validity of the proposed scheme is established by simulation of the cellular network usage in conjunction with the TV white space.The simulation results show clear improvements in both the user and the system performance with the cognitive coexistent cellular network compared with the traditional cellular network,and that the performance of the proposed user allocation scheme is superior to other user allocation schemes.展开更多
The KDOT (Kansas Department of Transportation) is currently adopting MEPDG (mechanistic-empirical pavement design guide) to replace the 1993 AASHTO (American Association of State Highway and Transportation Offici...The KDOT (Kansas Department of Transportation) is currently adopting MEPDG (mechanistic-empirical pavement design guide) to replace the 1993 AASHTO (American Association of State Highway and Transportation Officials) design method. The main objective of this study was to compare flexible pavement design using 1993 AASHTO design guide and MEPDG. Five newly built Superior PERforming Asphalt PAVEments (Superpave), designed using the 1993 AASHTO Design Guide, were selected as test sections for the design simulation study. Deflection data were collected approximately 8 to 10 weeks after construction using FWD (falling weight deflectometer). The FWD deflection data were used to back-calculate the pavement layer moduli using three different back-calculation programs. The existing pavement structures were analyzed for a 10-year analysis period. The maximum numbers of years the existing pavement structures will be in a serviceable condition as well as the minimum thicknesses of different layers to serve for 10-years were also determined. Effects of changing subgrade modulus, target distress, and reliability were also investigated. The MEPDG design analysis shows that the 1993 AASHTO Guide-designed flexible pavements do not show the distresses currently observed in Kansas for the 10-year design period. The MEPDG design simulation shows that the thinner the pavement sections, the higher the permanent deformation. The existing pavement structures can serve for more than 20 years as per the MEPDG design analysis if the default failure criteria and nationally-calibrated models are used.展开更多
The Earth, which is a planet connection with the evolution of the Solar system, was formed and evolved as part of the WHOLE, in close of the Universe. The awareness, knowledge, and understanding of our coexistence wit...The Earth, which is a planet connection with the evolution of the Solar system, was formed and evolved as part of the WHOLE, in close of the Universe. The awareness, knowledge, and understanding of our coexistence with the Universe may clarify a series of obscure problems of our existence, and, at the same time, may bring solutions for other acute problems which our modem society has to face, such as energy, nature preservation, the origin, evolution and adaptation of the living and especially of man to the environment, etc.. This paper is trying to theoretically break up the concept of environmenf' into four fundamental contexts: terrestrial, lunar, solar-planetary, and cosmic context. We intend to approach the four contexts that distinctly and simultaneously influence life on the Earth using the interface theory which we developed in Informational Anthropology, Integronics and Biocosmological Anthropology. We consider that the living adapted and developed in a differentiated way according to the impact of these contexts. They may be the source for the four causalities Aristotle intuited, as well as the cause of many still unknown phenomena that diversified man's evolution and variability (Ackrill 1997; Falcon 2008).展开更多
A service life model of NAND flash and threshold voltage shift process is proposed to calculate the service life and endurance.The relationships among achievable program/erase(P/E) cycles,recovery time,bad block rate ...A service life model of NAND flash and threshold voltage shift process is proposed to calculate the service life and endurance.The relationships among achievable program/erase(P/E) cycles,recovery time,bad block rate and storage time are analyzed.The achievable endurance and service life of a NAND flash are evaluated based on a flash cell degradation and recovery model by varying recovery time,badblock rate,and storage time.It is proposed to improve the service lifetime of solid state disk by both relaxing the bad block rate limitation and retention time while extending the recovery time.The results indicate that endurance can be improved by 17 times if the storage time guarantee is reduced from 10 a to 1 a with 105 s recovery time inserted between cycles.展开更多
Deployment of nodes based on K-barrier coverage in an underground wireless sensor network is described. The network has automatic routing recovery by using a basic information table (BIT) for each node. An RSSI positi...Deployment of nodes based on K-barrier coverage in an underground wireless sensor network is described. The network has automatic routing recovery by using a basic information table (BIT) for each node. An RSSI positioning algorithm based on a path loss model in the coal mine is used to calculate the path loss in real time within the actual lane way environment. Simulation results show that the packet loss can be controlled to less than 15% by the routing recovery algorithm under special recovery circum- stances. The location precision is within 5 m, which greatly enhances performance compared to tradi- tional frequency location systems. This approach can meet the needs for accurate location underground.展开更多
Objective To explore the impact of combination use of prostaglandin analogue and cholinergic agonists on main matrix metalloproteinases(MMPs)synthesized by albino rabbit ciliary muscle.Methods Normal adult albino rabb...Objective To explore the impact of combination use of prostaglandin analogue and cholinergic agonists on main matrix metalloproteinases(MMPs)synthesized by albino rabbit ciliary muscle.Methods Normal adult albino rabbits were divided into the control group,2%pilocarpine group,0.004%travoprost group and travoprost plus pilocarpine group.Two rabbits in the control group were executed after treated with normal saline for one day.Two rabbits were separately executed on the 7th,14th and 24th day of the treatment in each drug treated group.In each subgroup ciliary muscle band of 4 eyes was taken and made into homogenate.The MMPs activities of 10 subgroups were assayed by zymography.Bands’intensity which represents the activity of MMPs was measured by the UltraViolet Illumination system.Results A bright band of MMP-1/2 was showed on each lane at the position corresponding to the molecular weight of 62 kD in the ciliary smooth muscles electrophoresis.When ion Zn and Ca was displaced by MMPs inhibitor EDTA,this bright band disappeared.Compared with the control group,MMP1/2 activity increased by 4.0%,4.1%and 14.0%after 7,14 and 24 days of pilocarpine treatment.Corresponding data was23.2%,61.7%and 111.5%in the travoprost group and 49.3%,68.0%and 88.4%in the travoprost plus pilocarpine group.Conclusions Pilocarpine has little effect on activity of MMP1/2.Travoprost can increase activity of MMP1/2 gradually.Activity of MMP1/2 is rapidly increased by pilocarpine combined with travoprost,but shows small change with the prolonged treatment.展开更多
Objective:To observe the clinical effects of the combined use of acupuncture and herbal medicine for treatment of chloasma.Methods:Totally 60 patients were randomly divided into a treatment group of 30 cases,treated b...Objective:To observe the clinical effects of the combined use of acupuncture and herbal medicine for treatment of chloasma.Methods:Totally 60 patients were randomly divided into a treatment group of 30 cases,treated by acupuncture and herbal medicine,and a control group of 30 cases,administered Vitamin C and Vitamin E.The clinical effects were observed.Results:The total effective rate of the treatment group is 93.3%better than that of the control group(76.7%) ,the difference was significant(P<0.01) .Conclusion:Combined use of acupuncture and herbal medicine may yield definite therapeutic effects in treating chloasma patients.展开更多
OBJECTIVE: To evaluate the clinical effects of Xiyan-ping injection intervention in pediatric patients with mild hand foot and mouth disease(HFMD).METHODS: A total of 329 patients were stratified and block-randomized ...OBJECTIVE: To evaluate the clinical effects of Xiyan-ping injection intervention in pediatric patients with mild hand foot and mouth disease(HFMD).METHODS: A total of 329 patients were stratified and block-randomized for symptomatic treatment of HFMD and assigned to one of the following groups: Western Medicine(group A, n = 103), Xiyanping injection(group B, n = 109), or Xiyanping injection and symptomatic treatment using Western Medicine(group C, n = 117). During the trial, fever,rash, ulcers of the mouth were observed among participants in each group before and after treatment, and conversion rates from mild to severe HFMD were measured.RESULTS: After 3-7 days' treatment, no significant differences in the conversion rates from mild to severe HFMD were observed among the three groups(P > 0.05). There was a significantly low number of patients with the onset time of antifebrile effect,vanished time of hand and foot rashes and cumulative time for the ulcers in the mouth vanished,among the three groups(P < 0.05, P < 0.01). The onset time of antifebrile effect of patients in groups B and C were markedly shorter compared with those in group A(P < 0.05, P < 0.01); there was no statically significant difference observed between groups B and C(P > 0.05). No significant differences were observed in the time for body temperature recovery among the three groups(P > 0.05). There were no significant differences in adverse effects among the three groups(P > 0.05).CONCLUSION: Xiyanping injection together with use of Western Medicine is most effective for symptomatic treatment of mild HFMD. No severe adverse reactions were observed.展开更多
基金Supported by the Joint Research Funds of Dalian University of Technology and Shenyang Automation Institute,Chinese Academy of Sciences
文摘A new kind of region pair grey difference classifier was proposed. The regions in pairs associated to form a feature were not necessarily directly-connected, but were selected dedicatedly to the grey transition between regions coinciding with the face pattern structure. Fifteen brighter and darker region pairs were chosen to form the region pair grey difference features with high discriminant capabilities. Instead of using both false acceptance rate and false rejection rate, the mutual information was used as a unified metric for evaluating the classifying performance. The parameters of specified positions, areas and grey difference bias for each single region pair feature were selected by an optimization processing aiming at maximizing the mutual information between the region pair feature and classifying distribution, respectively. An additional region-based feature depicting the correlation between global region grey intensity patterns was also proposed. Compared with the result of Viola-like approach using over 2 000 features, the proposed approach can achieve similar error rates with only 16 features and 1/6 implementation time on controlled illumination images.
文摘The combination of Morgenstern-Price Method (MPM) with Response Surface Method (RSM) improves the eonventional RSM by replacing Finite-Element Method (FEM) with MPM, which is a type of reliability analysis method-RSM based on MPM, and makes the computing process simpler. The stability of the slope was re-evaluated by use of Monte Carlo method (MCM) and the result contrasted with the fore is the conclusion. The reliability analysis of the artificial slope in Donggang Power Station was carried on, and obtained the reliable charaeteristics, which provided basis for the project.
文摘Gradual shift has been observed lately of dam safety procedures from the conventional technical based towards a wider scope of risk management procedure based on risk analysis. The new approach considers the likelihood level of occurrence of a multitude of hazards and the magnitude of the resulting possible consequences in case of failure using rational cause and effect arguments. Most dam owners are shifting towards the use of the new risk based procedures; and even governments themselves are moving towards formalizing the new trend. Legislations in the United States were promulgated [1] after serious dam failures and the adoption of stringent levels of scrutiny led such federal dam owners to pioneer in this field and in developing the concepts and methods required. The comer stone in risk analysis is the definition of the potential modes that may lead to failure and assessment of the likelihood levels of their occurrence and possible category of the consequences which, after thorough evaluation, will shape the decision making. This type of analysis was applied to Mosul Dam as a case study and resulted in definite recommendations.
文摘Municipalities are autonomous economic and administrative entities, with common actions and responsibilities. Moreover, all Municipalities are quite different considering specific characteristics, such as geographic, demographic, and economic. The aim of this research is to separate the entire sample of Municipalities in Greece into categories, based on the effectiveness of financial management and financial performance into effective and ineffective ones. For the separation of the sample into groups, cluster analysis was preferred. For this reason, three variables were used: the lending capacity of the Municipality, flexibility in making non-investment costs, and flexibility in investment spending. These three variables were considered to be the key dimensions of effectiveness in financial management and therefore their use, representatively describes the effectiveness of Greek Municipalities. Thus, this paper presents the literature review of the financial effectiveness of Municipalities and the methodology of an empirical research through structured questionnaire that was sent to the entire population of Greek Municipalities, characterized in this way with considerable heterogeneity. In this way, it investigates the views of Mayors in the two categories of Municipalities (effective and non effective financial management and financial performance) as regards: (a) the biggest problems faced by the citizens in their Municipality, and (b) the biggest personnel problems faced by their Municipality. Concluding, the prioritization of both problems seems to be the same for both groups of Municipalities. The frequency of responses differs slightly and differences are not so large that financial performance can be considered to affect respondents' opinions.
文摘The emotional factors play an important role in the process of language learning. Exploration of the emotional problems in the process of English learning can promote the emotional communication between teachers and students. The organic combination of the two aspects of cognitive and emotional can help to finish the promotion of cognitive and education with emotion. People abroad have achieved many results about the research, while further research in domestic is still rare. This paper mainly analyzes the main emotional problems influencing the English leaming, clarifies the importance of using emotional strategy in English learning, points out the way of improving learning effect by affective strategies, thus to guide the students form the corresponding emotion strategy, effectively use in English learning, and improve the English learning.
基金funded by the Prix Jeune Chercheur of the Fondation Bettencourt-Schueller
文摘Proper phylogenetic reconstruction is crucial for understanding many evolutionary phenomena. In spite of the great success of molecular phylogenetics, DNA signal still may be limited by some intrinsic constraints such as codon usage bias. The phylogenetic relationships between the five species subgroups of the Drosophila saltans group are a good example of conflicting molecular phylogenies drawn from different genes due to an ancestral substitutional shift. Here, forty morphological characters were analyzed using the same set of species used in previous molecular studies, with at least a single representative of each subgroup. The cladistic analysis was in disagreement with most of the previous hypotheses in placing the sturtevanti subgroup as an early branch, whereas the four remaining subgroups form a well supported clade that can be further subdivided into two sister clades: one containing the cordata and the elliptica subgroups, whereas the second includes the parasaltans and the saltans subgroups. The molecular evolution (codon usage bias) of the saltans group were revised in light of the present finding. The analysis highlights the important role of morphology in phylogeny reconstruction and in understanding molecular evolutionary phenomena.
基金Supported by the National Natural Science Foundation of China(No.61271230)the Starting Fund for Science Research of NJIT(No.YKJ201205)the Open Research Fund of National Mobile Communications Research Laboratory(No.2013D02)
文摘In order to address spectrum resource scarcity in traditional cellular networks,television(TV)white space is considered as a potential solution to offload a portion of network traffic and enlarge network capacity.This paper describes a cognitive cellular network which allocates low geometry users to the TV white space based on a proportional fair criterion.An uplink user allocation scheme is proposed and the validity of the proposed scheme is established by simulation of the cellular network usage in conjunction with the TV white space.The simulation results show clear improvements in both the user and the system performance with the cognitive coexistent cellular network compared with the traditional cellular network,and that the performance of the proposed user allocation scheme is superior to other user allocation schemes.
文摘The KDOT (Kansas Department of Transportation) is currently adopting MEPDG (mechanistic-empirical pavement design guide) to replace the 1993 AASHTO (American Association of State Highway and Transportation Officials) design method. The main objective of this study was to compare flexible pavement design using 1993 AASHTO design guide and MEPDG. Five newly built Superior PERforming Asphalt PAVEments (Superpave), designed using the 1993 AASHTO Design Guide, were selected as test sections for the design simulation study. Deflection data were collected approximately 8 to 10 weeks after construction using FWD (falling weight deflectometer). The FWD deflection data were used to back-calculate the pavement layer moduli using three different back-calculation programs. The existing pavement structures were analyzed for a 10-year analysis period. The maximum numbers of years the existing pavement structures will be in a serviceable condition as well as the minimum thicknesses of different layers to serve for 10-years were also determined. Effects of changing subgrade modulus, target distress, and reliability were also investigated. The MEPDG design analysis shows that the 1993 AASHTO Guide-designed flexible pavements do not show the distresses currently observed in Kansas for the 10-year design period. The MEPDG design simulation shows that the thinner the pavement sections, the higher the permanent deformation. The existing pavement structures can serve for more than 20 years as per the MEPDG design analysis if the default failure criteria and nationally-calibrated models are used.
文摘The Earth, which is a planet connection with the evolution of the Solar system, was formed and evolved as part of the WHOLE, in close of the Universe. The awareness, knowledge, and understanding of our coexistence with the Universe may clarify a series of obscure problems of our existence, and, at the same time, may bring solutions for other acute problems which our modem society has to face, such as energy, nature preservation, the origin, evolution and adaptation of the living and especially of man to the environment, etc.. This paper is trying to theoretically break up the concept of environmenf' into four fundamental contexts: terrestrial, lunar, solar-planetary, and cosmic context. We intend to approach the four contexts that distinctly and simultaneously influence life on the Earth using the interface theory which we developed in Informational Anthropology, Integronics and Biocosmological Anthropology. We consider that the living adapted and developed in a differentiated way according to the impact of these contexts. They may be the source for the four causalities Aristotle intuited, as well as the cause of many still unknown phenomena that diversified man's evolution and variability (Ackrill 1997; Falcon 2008).
基金Project(61171017)supported by the National Natural Science Foundation of China
文摘A service life model of NAND flash and threshold voltage shift process is proposed to calculate the service life and endurance.The relationships among achievable program/erase(P/E) cycles,recovery time,bad block rate and storage time are analyzed.The achievable endurance and service life of a NAND flash are evaluated based on a flash cell degradation and recovery model by varying recovery time,badblock rate,and storage time.It is proposed to improve the service lifetime of solid state disk by both relaxing the bad block rate limitation and retention time while extending the recovery time.The results indicate that endurance can be improved by 17 times if the storage time guarantee is reduced from 10 a to 1 a with 105 s recovery time inserted between cycles.
基金supported by the National Key Technology R&D Program of China (No. 2008BAH37B05095)
文摘Deployment of nodes based on K-barrier coverage in an underground wireless sensor network is described. The network has automatic routing recovery by using a basic information table (BIT) for each node. An RSSI positioning algorithm based on a path loss model in the coal mine is used to calculate the path loss in real time within the actual lane way environment. Simulation results show that the packet loss can be controlled to less than 15% by the routing recovery algorithm under special recovery circum- stances. The location precision is within 5 m, which greatly enhances performance compared to tradi- tional frequency location systems. This approach can meet the needs for accurate location underground.
文摘Objective To explore the impact of combination use of prostaglandin analogue and cholinergic agonists on main matrix metalloproteinases(MMPs)synthesized by albino rabbit ciliary muscle.Methods Normal adult albino rabbits were divided into the control group,2%pilocarpine group,0.004%travoprost group and travoprost plus pilocarpine group.Two rabbits in the control group were executed after treated with normal saline for one day.Two rabbits were separately executed on the 7th,14th and 24th day of the treatment in each drug treated group.In each subgroup ciliary muscle band of 4 eyes was taken and made into homogenate.The MMPs activities of 10 subgroups were assayed by zymography.Bands’intensity which represents the activity of MMPs was measured by the UltraViolet Illumination system.Results A bright band of MMP-1/2 was showed on each lane at the position corresponding to the molecular weight of 62 kD in the ciliary smooth muscles electrophoresis.When ion Zn and Ca was displaced by MMPs inhibitor EDTA,this bright band disappeared.Compared with the control group,MMP1/2 activity increased by 4.0%,4.1%and 14.0%after 7,14 and 24 days of pilocarpine treatment.Corresponding data was23.2%,61.7%and 111.5%in the travoprost group and 49.3%,68.0%and 88.4%in the travoprost plus pilocarpine group.Conclusions Pilocarpine has little effect on activity of MMP1/2.Travoprost can increase activity of MMP1/2 gradually.Activity of MMP1/2 is rapidly increased by pilocarpine combined with travoprost,but shows small change with the prolonged treatment.
文摘Objective:To observe the clinical effects of the combined use of acupuncture and herbal medicine for treatment of chloasma.Methods:Totally 60 patients were randomly divided into a treatment group of 30 cases,treated by acupuncture and herbal medicine,and a control group of 30 cases,administered Vitamin C and Vitamin E.The clinical effects were observed.Results:The total effective rate of the treatment group is 93.3%better than that of the control group(76.7%) ,the difference was significant(P<0.01) .Conclusion:Combined use of acupuncture and herbal medicine may yield definite therapeutic effects in treating chloasma patients.
基金Supported by State Administration of Traditional Chinese Medicine(No.200907001)Natural Science Foundation of China(No.81603574)
文摘OBJECTIVE: To evaluate the clinical effects of Xiyan-ping injection intervention in pediatric patients with mild hand foot and mouth disease(HFMD).METHODS: A total of 329 patients were stratified and block-randomized for symptomatic treatment of HFMD and assigned to one of the following groups: Western Medicine(group A, n = 103), Xiyanping injection(group B, n = 109), or Xiyanping injection and symptomatic treatment using Western Medicine(group C, n = 117). During the trial, fever,rash, ulcers of the mouth were observed among participants in each group before and after treatment, and conversion rates from mild to severe HFMD were measured.RESULTS: After 3-7 days' treatment, no significant differences in the conversion rates from mild to severe HFMD were observed among the three groups(P > 0.05). There was a significantly low number of patients with the onset time of antifebrile effect,vanished time of hand and foot rashes and cumulative time for the ulcers in the mouth vanished,among the three groups(P < 0.05, P < 0.01). The onset time of antifebrile effect of patients in groups B and C were markedly shorter compared with those in group A(P < 0.05, P < 0.01); there was no statically significant difference observed between groups B and C(P > 0.05). No significant differences were observed in the time for body temperature recovery among the three groups(P > 0.05). There were no significant differences in adverse effects among the three groups(P > 0.05).CONCLUSION: Xiyanping injection together with use of Western Medicine is most effective for symptomatic treatment of mild HFMD. No severe adverse reactions were observed.