With the increasing popularity of cloud computing, there is an increased de mand for cloud resources in cloud. It has be come even more urgent to find solutions to improve resource utilization. From the per spective o...With the increasing popularity of cloud computing, there is an increased de mand for cloud resources in cloud. It has be come even more urgent to find solutions to improve resource utilization. From the per spective of a cloud consumer, a cloud applica tion processes a large information flow in volving user actions that access resources, but little work has so far been devoted to research from the perspective of the interaction be tween the user and the cloud application. In this paper, we analyze the interaction in detail, and propose a general mathematical interac tion model to formulate the challenge pertain ing to storage resource allocation as an opti mization problem, focusing on minimizing both the user's cost and server's consumption. A potential response mechanism is then de signed based on the interaction model. Fur thermore, the proposed model is used to ex plore strategies when multiple users access the same file simultaneously. Additionally, an improved queuing system, namely M/ G~ oo queue with standby, is introduced. Finally, an evaluation is presented to verify the interac- tion model.展开更多
This paper focuses on robust control problems for supercavitating vehicles in the vertical plane. Firstly, for the mathematical model with mismatched uncertainties, the robust sliding mode function is designed based o...This paper focuses on robust control problems for supercavitating vehicles in the vertical plane. Firstly, for the mathematical model with mismatched uncertainties, the robust sliding mode function is designed based on the guaranteed cost theory, and a sufficient condition for the existence is given in terms of linear matrix inequality (LMI). Secondly, a continuous sliding mode controller is proposed to handle the nonlinear, time - varying behavior of the vehicles. Simulation results demonstrate that the system responds rapidly and has good robust stability. Therefore, it provides theoretical references for further study on control problems of supercavitating vehicles.展开更多
In order to directly construct the mapping between multiple state parameters and remaining useful life(RUL),and reduce the interference of random error on prediction accuracy,a RUL prediction model of aeroengine based...In order to directly construct the mapping between multiple state parameters and remaining useful life(RUL),and reduce the interference of random error on prediction accuracy,a RUL prediction model of aeroengine based on principal component analysis(PCA)and one-dimensional convolution neural network(1D-CNN)is proposed in this paper.Firstly,multiple state parameters corresponding to massive cycles of aeroengine are collected and brought into PCA for dimensionality reduction,and principal components are extracted for further time series prediction.Secondly,the 1D-CNN model is constructed to directly study the mapping between principal components and RUL.Multiple convolution and pooling operations are applied for deep feature extraction,and the end-to-end RUL prediction of aeroengine can be realized.Experimental results show that the most effective principal component from the multiple state parameters can be obtained by PCA,and the long time series of multiple state parameters can be directly mapped to RUL by 1D-CNN,so as to improve the efficiency and accuracy of RUL prediction.Compared with other traditional models,the proposed method also has lower prediction error and better robustness.展开更多
A convolutional weighting (CW) scheme applied to a half-wavelength spacing array was proposed for multi-user system to joint STBC (space time block ceding) and beam forming (BF). The transmitting beam is equival...A convolutional weighting (CW) scheme applied to a half-wavelength spacing array was proposed for multi-user system to joint STBC (space time block ceding) and beam forming (BF). The transmitting beam is equivalent to the product of two sub-beams. One is used to realize interference suppression, while the other is employed to form a couple of uncorrelated channels from base station (BS) to the desited user (to meet the requirement of STBC) and to maximize SINR (signal-to-interference-plus noise ratio) at the desired receiver. As an optimum combination of STBC and beam forming, the proposed scheme can achieve both full diversity order of STBC and array gain of BF. Meanwhile, it can also effec- tively restrain multi-user interference by nulling. Simulation results show that the proposed scheme can significantly improve the BER (Bit Error Rate) performance and enhance system capacity as compared with the conventional eigen-beamforming (EBF) technique applied to a half-wavelength spacing array.展开更多
Optimization of antenna array pattern used in a spaceborne Synthetic Aperture Radar (SAR) system is considered in this study. A robust evolutionary algorithm, Non-dominated Sorting Genetic Algorithms (the improved NS...Optimization of antenna array pattern used in a spaceborne Synthetic Aperture Radar (SAR) system is considered in this study. A robust evolutionary algorithm, Non-dominated Sorting Genetic Algorithms (the improved NSGA-Ⅱ), is applied on a spaceborne SAR antenna pattern design. The system consists of two objective functions with two constraints. Pareto fronts are generated as a result of multi-objective optimization. After being validated by a test problem ZDT4, the algorithms are used to synthesize spaceborne SAR antenna radiation pattern. The good results with low Ambi- guity-to-Signal Ratio (ASR) and high directivity are obtained in the paper.展开更多
Shiga toxin B-subunit (STxB) from Shigella dysenteriae targets in vivo antigen to cancer cells, dendritic cells (DC) and B cells, which preferentially express the globotriaosylceramide (Gb3) receptor. This pivot...Shiga toxin B-subunit (STxB) from Shigella dysenteriae targets in vivo antigen to cancer cells, dendritic cells (DC) and B cells, which preferentially express the globotriaosylceramide (Gb3) receptor. This pivotal role has encouraged scientists to investigate fusing STxB with other clinical antigens. Due to the challenges of obtaining a functional soluble form of the recombinant STxB, such as formation of inclusion bodies during protein expression, scientists tend to combine STxB with vaccine candidates rather than using their genetically fused forms. In this work, we fused HPV16 E7 as a vaccine candidate to the recombinantly-produced STxB. To minimize the formation of inclusion bodies, we investigated a number of conditions during the expression procedure. Then various strategies were used in order to obtain high yield of soluble recombinant protein from E. coli which included the use of different host strains, reduction of cultivation temperature, as well as using different concentrations of IPTG and different additives (Glycin, Triton X-100, ZnC12). Our study demonstrated the importance of optimizing incubation parameters for recombinant protein expression in E. coli; also showed that the secretion production can be achieved over the course of a few hours when using additives such as glycine and Triton X-100. Interestingly, it was shown that when the culture mediums were supplemented by additives, there was an inverse ratio between time of induction (TOI) and the level of secreted protein at lower temperatures. This study determines the optimal conditions for high yield soluble E7-STxB expression and subsequently facilitates reaching a functionally soluble form of STxB-based vaccines, which can be considered as a potent vaccine candidate for cervical cancer.展开更多
With the spread use of the computers, a new crime space and method are presented for criminals. Thus computer evidence plays a key part in criminal cases. Traditional computer evidence searches require that the comput...With the spread use of the computers, a new crime space and method are presented for criminals. Thus computer evidence plays a key part in criminal cases. Traditional computer evidence searches require that the computer specialists know what is stored in the given computer. Binary-based information flow tracking which concerns the changes of control flow is an effective way to analyze the behavior of a program. The existing systems ignore the modifications of the data flow, which may be also a malicious behavior. Thus the function recognition is introduced to improve the information flow tracking. Function recognition is a helpful technique recognizing the function body from the software binary to analyze the binary code. And that no false positive and no false negative in our experiments strongly proves that our approach is effective.展开更多
The global financial and economic crisis has negatively affected all business units. Tough fight for the market position results in effort to create efficient methods to maintain company's competitiveness. Some of sm...The global financial and economic crisis has negatively affected all business units. Tough fight for the market position results in effort to create efficient methods to maintain company's competitiveness. Some of small and medium entrepreneurs have started to search the business allies. As an example of such possibility of cooperation the formation of clusters should be mention. The main intention of this paper is to demonstrate possibility for small and medium-sized enterprises (SMEs) to cooperatively penetrate new markets. Attention is focused mainly on a real export-oriented cluster. Ambition is to use costs and benefits analysis to test ability of the cluster to improve chances of companies to penetrate new markets. In order to link this analysis to real life as much as possible, existing cluster was used and on its accomplishments and failures costs and benefits of clustering are demonstrated.展开更多
The changes in utilization of agricultural land have gradually grown into one of the major factors impacting grain output in China. This study explores the various components of agricultural production in China from t...The changes in utilization of agricultural land have gradually grown into one of the major factors impacting grain output in China. This study explores the various components of agricultural production in China from the land utilization perspective, involving changes in grain production per unit area, multi-cropping index, and adjustment of agricultural structure. Compared with the record values, different research methodologies are used to analyze the po- tential of above three components. The results indicate that grain production potential of 65.68×109kg was unexploited in 2006, in which 45.8×109kg came from the restructuring in agriculture. So we can infer that the reduction of grain production in China could be primarily attributed to agricultural restructuring in recent years. So the productive poten- tial can be fully restored by increasing agricultural investment, or recovering agricultural structure in favorable condi- tions. So we can say that China’s current condition of food security is good.展开更多
This paper analyzes the launch price of the launch vehicles, domestic and abroad, studies the status and trend of the low cost launch vehicles, and introduces two measures to reduce the cost by means of evolved and di...This paper analyzes the launch price of the launch vehicles, domestic and abroad, studies the status and trend of the low cost launch vehicles, and introduces two measures to reduce the cost by means of evolved and disruptive technologies, utilizing the concept of low cost manufacturing and operating modes as well. This paper also analyzes the launch strategies for small satellites such as piggyback, networking launch, and single launch with a small launch vehicle(SLV). Finally, the development trend of reusable launch vehicles is discussed as well as the development prospects for China's reusable launch vehicle.展开更多
We point out a new route to deducing integration formulas, i.e., using the technique of integration within an ordered product (IWOP) of operators we derive some new integration formulas, which seems concise. As a by...We point out a new route to deducing integration formulas, i.e., using the technique of integration within an ordered product (IWOP) of operators we derive some new integration formulas, which seems concise. As a by-product, some new operator identities also appear.展开更多
Objective To explore the impact of combination use of prostaglandin analogue and cholinergic agonists on main matrix metalloproteinases(MMPs)synthesized by albino rabbit ciliary muscle.Methods Normal adult albino rabb...Objective To explore the impact of combination use of prostaglandin analogue and cholinergic agonists on main matrix metalloproteinases(MMPs)synthesized by albino rabbit ciliary muscle.Methods Normal adult albino rabbits were divided into the control group,2%pilocarpine group,0.004%travoprost group and travoprost plus pilocarpine group.Two rabbits in the control group were executed after treated with normal saline for one day.Two rabbits were separately executed on the 7th,14th and 24th day of the treatment in each drug treated group.In each subgroup ciliary muscle band of 4 eyes was taken and made into homogenate.The MMPs activities of 10 subgroups were assayed by zymography.Bands’intensity which represents the activity of MMPs was measured by the UltraViolet Illumination system.Results A bright band of MMP-1/2 was showed on each lane at the position corresponding to the molecular weight of 62 kD in the ciliary smooth muscles electrophoresis.When ion Zn and Ca was displaced by MMPs inhibitor EDTA,this bright band disappeared.Compared with the control group,MMP1/2 activity increased by 4.0%,4.1%and 14.0%after 7,14 and 24 days of pilocarpine treatment.Corresponding data was23.2%,61.7%and 111.5%in the travoprost group and 49.3%,68.0%and 88.4%in the travoprost plus pilocarpine group.Conclusions Pilocarpine has little effect on activity of MMP1/2.Travoprost can increase activity of MMP1/2 gradually.Activity of MMP1/2 is rapidly increased by pilocarpine combined with travoprost,but shows small change with the prolonged treatment.展开更多
A steam power plant can work as a dual purpose plant for simultaneous production of steam and elec-trical power. In this paper we seek the optimum integration of a steam power plant as a source and a site utility sys-...A steam power plant can work as a dual purpose plant for simultaneous production of steam and elec-trical power. In this paper we seek the optimum integration of a steam power plant as a source and a site utility sys-tem as a sink of steam and power. Estimation for the cogeneration potential prior to the design of a central utility system for site utility systems is vital to the targets for site fuel demand as well as heat and power production. In this regard, a new cogeneration targeting procedure is proposed for integration of a steam power plant and a site utility consisting of a process plant. The new methodology seeks the optimal integration based on a new cogenera-tion targeting scheme. In addition, a modified site utility grand composite curve(SUGCC) diagram is proposed and compared to the original SUGCC. A gas fired steam power plant and a process site utility is considered in a case study. The applicability of the developed procedure is tested against other design methods(STAR? and Thermoflex software) through a case study. The proposed method gives comparable results, and the targeting method is used for optimal integration of steam levels. Identifying optimal conditions of steam levels for integration is important in the design of utility systems, as the selection of steam levels in a steam power plant and site utility for integration greatly influences the potential for cogeneration and energy recovery. The integration of steam levels of the steam power plant and the site utility system in the case study demonstrates the usefulness of the method for reducing the overall energy consumption for the site.展开更多
基金supported in part by the National Natural Science Foundation of China under Grant No. 61271199the Fundamental Research Funds in Beijing Jiaotong University under Grant No. W11JB00630
文摘With the increasing popularity of cloud computing, there is an increased de mand for cloud resources in cloud. It has be come even more urgent to find solutions to improve resource utilization. From the per spective of a cloud consumer, a cloud applica tion processes a large information flow in volving user actions that access resources, but little work has so far been devoted to research from the perspective of the interaction be tween the user and the cloud application. In this paper, we analyze the interaction in detail, and propose a general mathematical interac tion model to formulate the challenge pertain ing to storage resource allocation as an opti mization problem, focusing on minimizing both the user's cost and server's consumption. A potential response mechanism is then de signed based on the interaction model. Fur thermore, the proposed model is used to ex plore strategies when multiple users access the same file simultaneously. Additionally, an improved queuing system, namely M/ G~ oo queue with standby, is introduced. Finally, an evaluation is presented to verify the interac- tion model.
基金Supported by the National Natural Science Foundation of China( No. 10802026) and Research Fund for the Doctoral Program of Higher Education of China ( No. 200802130003 ).
文摘This paper focuses on robust control problems for supercavitating vehicles in the vertical plane. Firstly, for the mathematical model with mismatched uncertainties, the robust sliding mode function is designed based on the guaranteed cost theory, and a sufficient condition for the existence is given in terms of linear matrix inequality (LMI). Secondly, a continuous sliding mode controller is proposed to handle the nonlinear, time - varying behavior of the vehicles. Simulation results demonstrate that the system responds rapidly and has good robust stability. Therefore, it provides theoretical references for further study on control problems of supercavitating vehicles.
基金supported by Jiangsu Social Science Foundation(No.20GLD008)Science,Technology Projects of Jiangsu Provincial Department of Communications(No.2020Y14)Joint Fund for Civil Aviation Research(No.U1933202)。
文摘In order to directly construct the mapping between multiple state parameters and remaining useful life(RUL),and reduce the interference of random error on prediction accuracy,a RUL prediction model of aeroengine based on principal component analysis(PCA)and one-dimensional convolution neural network(1D-CNN)is proposed in this paper.Firstly,multiple state parameters corresponding to massive cycles of aeroengine are collected and brought into PCA for dimensionality reduction,and principal components are extracted for further time series prediction.Secondly,the 1D-CNN model is constructed to directly study the mapping between principal components and RUL.Multiple convolution and pooling operations are applied for deep feature extraction,and the end-to-end RUL prediction of aeroengine can be realized.Experimental results show that the most effective principal component from the multiple state parameters can be obtained by PCA,and the long time series of multiple state parameters can be directly mapped to RUL by 1D-CNN,so as to improve the efficiency and accuracy of RUL prediction.Compared with other traditional models,the proposed method also has lower prediction error and better robustness.
基金Supported by the National Natural Science Foundation of Chin(No. 60302020).
文摘A convolutional weighting (CW) scheme applied to a half-wavelength spacing array was proposed for multi-user system to joint STBC (space time block ceding) and beam forming (BF). The transmitting beam is equivalent to the product of two sub-beams. One is used to realize interference suppression, while the other is employed to form a couple of uncorrelated channels from base station (BS) to the desited user (to meet the requirement of STBC) and to maximize SINR (signal-to-interference-plus noise ratio) at the desired receiver. As an optimum combination of STBC and beam forming, the proposed scheme can achieve both full diversity order of STBC and array gain of BF. Meanwhile, it can also effec- tively restrain multi-user interference by nulling. Simulation results show that the proposed scheme can significantly improve the BER (Bit Error Rate) performance and enhance system capacity as compared with the conventional eigen-beamforming (EBF) technique applied to a half-wavelength spacing array.
文摘Optimization of antenna array pattern used in a spaceborne Synthetic Aperture Radar (SAR) system is considered in this study. A robust evolutionary algorithm, Non-dominated Sorting Genetic Algorithms (the improved NSGA-Ⅱ), is applied on a spaceborne SAR antenna pattern design. The system consists of two objective functions with two constraints. Pareto fronts are generated as a result of multi-objective optimization. After being validated by a test problem ZDT4, the algorithms are used to synthesize spaceborne SAR antenna radiation pattern. The good results with low Ambi- guity-to-Signal Ratio (ASR) and high directivity are obtained in the paper.
基金supported by Research Council of Shiraz University of Medical Sciences (91-01-36-4417), Shiraz, Iran
文摘Shiga toxin B-subunit (STxB) from Shigella dysenteriae targets in vivo antigen to cancer cells, dendritic cells (DC) and B cells, which preferentially express the globotriaosylceramide (Gb3) receptor. This pivotal role has encouraged scientists to investigate fusing STxB with other clinical antigens. Due to the challenges of obtaining a functional soluble form of the recombinant STxB, such as formation of inclusion bodies during protein expression, scientists tend to combine STxB with vaccine candidates rather than using their genetically fused forms. In this work, we fused HPV16 E7 as a vaccine candidate to the recombinantly-produced STxB. To minimize the formation of inclusion bodies, we investigated a number of conditions during the expression procedure. Then various strategies were used in order to obtain high yield of soluble recombinant protein from E. coli which included the use of different host strains, reduction of cultivation temperature, as well as using different concentrations of IPTG and different additives (Glycin, Triton X-100, ZnC12). Our study demonstrated the importance of optimizing incubation parameters for recombinant protein expression in E. coli; also showed that the secretion production can be achieved over the course of a few hours when using additives such as glycine and Triton X-100. Interestingly, it was shown that when the culture mediums were supplemented by additives, there was an inverse ratio between time of induction (TOI) and the level of secreted protein at lower temperatures. This study determines the optimal conditions for high yield soluble E7-STxB expression and subsequently facilitates reaching a functionally soluble form of STxB-based vaccines, which can be considered as a potent vaccine candidate for cervical cancer.
基金This work is supported by National Natural Science Foundation of China (Grant No.60773093, 60873209, and 60970107), the Key Program for Basic Research of Shanghai (Grant No. 09JC1407900, 09510701600, 10511500100), IBM SUR Funding and IBM Research-China JP Funding, and Key Lab of Information Network Security, Ministry of Public Security.
文摘With the spread use of the computers, a new crime space and method are presented for criminals. Thus computer evidence plays a key part in criminal cases. Traditional computer evidence searches require that the computer specialists know what is stored in the given computer. Binary-based information flow tracking which concerns the changes of control flow is an effective way to analyze the behavior of a program. The existing systems ignore the modifications of the data flow, which may be also a malicious behavior. Thus the function recognition is introduced to improve the information flow tracking. Function recognition is a helpful technique recognizing the function body from the software binary to analyze the binary code. And that no false positive and no false negative in our experiments strongly proves that our approach is effective.
文摘The global financial and economic crisis has negatively affected all business units. Tough fight for the market position results in effort to create efficient methods to maintain company's competitiveness. Some of small and medium entrepreneurs have started to search the business allies. As an example of such possibility of cooperation the formation of clusters should be mention. The main intention of this paper is to demonstrate possibility for small and medium-sized enterprises (SMEs) to cooperatively penetrate new markets. Attention is focused mainly on a real export-oriented cluster. Ambition is to use costs and benefits analysis to test ability of the cluster to improve chances of companies to penetrate new markets. In order to link this analysis to real life as much as possible, existing cluster was used and on its accomplishments and failures costs and benefits of clustering are demonstrated.
基金Under the auspices of National Key Technologies R&D Program of China (No. 2006BAB15B02)National Natural Science Foundation of China (No. 40671009)
文摘The changes in utilization of agricultural land have gradually grown into one of the major factors impacting grain output in China. This study explores the various components of agricultural production in China from the land utilization perspective, involving changes in grain production per unit area, multi-cropping index, and adjustment of agricultural structure. Compared with the record values, different research methodologies are used to analyze the po- tential of above three components. The results indicate that grain production potential of 65.68×109kg was unexploited in 2006, in which 45.8×109kg came from the restructuring in agriculture. So we can infer that the reduction of grain production in China could be primarily attributed to agricultural restructuring in recent years. So the productive poten- tial can be fully restored by increasing agricultural investment, or recovering agricultural structure in favorable condi- tions. So we can say that China’s current condition of food security is good.
文摘This paper analyzes the launch price of the launch vehicles, domestic and abroad, studies the status and trend of the low cost launch vehicles, and introduces two measures to reduce the cost by means of evolved and disruptive technologies, utilizing the concept of low cost manufacturing and operating modes as well. This paper also analyzes the launch strategies for small satellites such as piggyback, networking launch, and single launch with a small launch vehicle(SLV). Finally, the development trend of reusable launch vehicles is discussed as well as the development prospects for China's reusable launch vehicle.
基金*Supported by the National Natural Science Foundation of China under Grant No. 10775097, and the Natural Science Foundation of Heze University of Shandong Province, under Crant No. XY07WL01
文摘We point out a new route to deducing integration formulas, i.e., using the technique of integration within an ordered product (IWOP) of operators we derive some new integration formulas, which seems concise. As a by-product, some new operator identities also appear.
文摘Objective To explore the impact of combination use of prostaglandin analogue and cholinergic agonists on main matrix metalloproteinases(MMPs)synthesized by albino rabbit ciliary muscle.Methods Normal adult albino rabbits were divided into the control group,2%pilocarpine group,0.004%travoprost group and travoprost plus pilocarpine group.Two rabbits in the control group were executed after treated with normal saline for one day.Two rabbits were separately executed on the 7th,14th and 24th day of the treatment in each drug treated group.In each subgroup ciliary muscle band of 4 eyes was taken and made into homogenate.The MMPs activities of 10 subgroups were assayed by zymography.Bands’intensity which represents the activity of MMPs was measured by the UltraViolet Illumination system.Results A bright band of MMP-1/2 was showed on each lane at the position corresponding to the molecular weight of 62 kD in the ciliary smooth muscles electrophoresis.When ion Zn and Ca was displaced by MMPs inhibitor EDTA,this bright band disappeared.Compared with the control group,MMP1/2 activity increased by 4.0%,4.1%and 14.0%after 7,14 and 24 days of pilocarpine treatment.Corresponding data was23.2%,61.7%and 111.5%in the travoprost group and 49.3%,68.0%and 88.4%in the travoprost plus pilocarpine group.Conclusions Pilocarpine has little effect on activity of MMP1/2.Travoprost can increase activity of MMP1/2 gradually.Activity of MMP1/2 is rapidly increased by pilocarpine combined with travoprost,but shows small change with the prolonged treatment.
文摘A steam power plant can work as a dual purpose plant for simultaneous production of steam and elec-trical power. In this paper we seek the optimum integration of a steam power plant as a source and a site utility sys-tem as a sink of steam and power. Estimation for the cogeneration potential prior to the design of a central utility system for site utility systems is vital to the targets for site fuel demand as well as heat and power production. In this regard, a new cogeneration targeting procedure is proposed for integration of a steam power plant and a site utility consisting of a process plant. The new methodology seeks the optimal integration based on a new cogenera-tion targeting scheme. In addition, a modified site utility grand composite curve(SUGCC) diagram is proposed and compared to the original SUGCC. A gas fired steam power plant and a process site utility is considered in a case study. The applicability of the developed procedure is tested against other design methods(STAR? and Thermoflex software) through a case study. The proposed method gives comparable results, and the targeting method is used for optimal integration of steam levels. Identifying optimal conditions of steam levels for integration is important in the design of utility systems, as the selection of steam levels in a steam power plant and site utility for integration greatly influences the potential for cogeneration and energy recovery. The integration of steam levels of the steam power plant and the site utility system in the case study demonstrates the usefulness of the method for reducing the overall energy consumption for the site.