[ Objective] The aim of this study was to provide a theoretical basis for the prevention and treatment of highly pathogenic porcine reproductive and respiratory syndrome （HP-PRRS）. [Method] Antigen location and hist...[ Objective] The aim of this study was to provide a theoretical basis for the prevention and treatment of highly pathogenic porcine reproductive and respiratory syndrome （HP-PRRS）. [Method] Antigen location and histopathological observation in natural cases infected by highly pathogenic porcine reproductive and respiratory syndrome virus （HP-PRRSV） were analyzed by immunohistochemistry and H. E. staining. [Result] The virus antigen mainly existed in epithelial calls, and also a few in mecrophages, lymphocytes and brain nerve cells. [ Conclusion] The cell and tissue tropism of HP-PRRSV strain in natural cases is different from that of previous strains.展开更多
Esophageal polyps are very rare,One case of giant fibrovascular polyp of the esophagus was described.The patient had symptoms of dysphagia and hematemesis.After examinations,the diagnosis of esophageal leiomyoma was m...Esophageal polyps are very rare,One case of giant fibrovascular polyp of the esophagus was described.The patient had symptoms of dysphagia and hematemesis.After examinations,the diagnosis of esophageal leiomyoma was made,In the process of thoracie exploration,esophageal polyp was removed,The pathological diagnosis postoperation was giant fibrovascular polyp of the esophagus associated with mucoid degeneration.展开更多
Objective： To analyze the current situation of syphilis in the sexually transmitted diseases （STDs） clinic, from January 1994 to December 2002 was studied. Methods： All syphilis patients were confirmed by history,...Objective： To analyze the current situation of syphilis in the sexually transmitted diseases （STDs） clinic, from January 1994 to December 2002 was studied. Methods： All syphilis patients were confirmed by history, physical examination, dark-field microscopy of samples taken from the chancre or satellite lymph nodes,or positive serological tests. Results： From 1994 to 2002, there were 2067 cases of early syphilis, accounting for 20.01% （2067/10330） of all STD cases. The annual proportion of syphilis cases among all STD cases from 1994 to 2002 was 0.57%, 0.53%, 3.54%, 16.20%, 31.29%, 27.88%, 25.63%, 17.11%, 10.48%, respectively. Of 2067 syphilis patients,49.64% （1026/2067） were male and 50.36% （1041/2067） were female. 44.75% （925/2067） of all cases presented with primary syphilis, 44.90% （928/2067） with secondary syphilis, 9.77% （202/2067） with latent syphilis （without any conspicuous clinical signs or symptoms）, and 0.58% （12/2067） with congenital syphilis. The 30-39 year old cohort accounted for the largest proportion, at 37.68% （779/2067） of all syphilis cases. The 20-29 year old cohort also accounted for a large proportion, at 37.20% （769/2067） of all cases,followed by the 40-49 year old cohort, at 17.95% （371/2067）. Syphilis was most prevalent among the unemployed,self-employed laborers, and office workers in decreasing order. The majority of cases were graduates of either primary school, high school, or college. Of all syphilis cases, 87.86% （1816/2067） were married, and 12.14%（251/2067, including children） were unmarried. 76.78% （1587/2067） of all cases were acquired through extramarital intercourse. 14.03% （290/2067） of cases were infected by their spouses. 0.58% （12/2067） of cases were due to vertical transmission. 8.61% （178） of cases were acquired through indirect contact. Conclusion： The proportion of syphilis infection among all STDs remained stable from 1994 to 1995,quickly and dramatically increased from 1996 to 1999,and then gradually tapered down from 2000 to 2002. The incidence of congenital syphilis infections increased throughout the study period.展开更多
AIM:To investigate barriers to colorectal cancer(CRC) screening in a community population.METHODS:We conducted a community-based case-control study in an urban Chinese population by questionnaire.Cases were selected f...AIM:To investigate barriers to colorectal cancer(CRC) screening in a community population.METHODS:We conducted a community-based case-control study in an urban Chinese population by questionnaire.Cases were selected from those completing both a fecal occult blood test(FOBT) case and colonoscopy in a CRC screening program in 2004.Control groups were matched by gender, age group and community.Control 1 included those having a positive FOBT but refusing a colonoscopy.Control 2 included those who refused both an FOBT and colonoscopy.RESULTS:The impact of occupation on willingness to attend a colorectal screening program differed by gender.P for heterogeneity was 0.009 for case vs control group 1, 0.01 for case versus control group 2, and 0.80 for control group 1 vs 2.Poor awareness of CRC and its screening program, characteristics of screening tests, and lack of time affected the screening rate.Financial support, fear of pain and bowel preparation were barriers to a colonoscopy as a screening test.Eighty-two percent of control group 1 and 87.1% of control group 2 were willing attend if the colonoscopy was free, but only 56.3% and 53.1%, respectively, if it was self-paid.Multivariate odds ratios for case vs control group 1 were 0.10 among those unwilling to attend a free colonoscopy and 0.50 among those unwilling to attend a self-paid colonoscopy.CONCLUSION:Raising the public awareness of CRC and its screening, integrating CRC screening into the health care system, and using a painless colonoscopy would increase its screening rate.展开更多
The anti-arrhythmic agent amiodarone （AD） is associated with numerous adverse effects, but serious liver disease is rare. The improved safety of administration of daily low doses of AD has already been established a...The anti-arrhythmic agent amiodarone （AD） is associated with numerous adverse effects, but serious liver disease is rare. The improved safety of administration of daily low doses of AD has already been established and this regimen is used for long-term medication. Nevertheless, asymptomatic continuous liver injury by AD may increase the risk of step-wise progression of non-alcoholic fatty liver disease. We present an autopsy case of AD-induced liver cirrhosis in a patient who had been treated with a low dose of AD （200 rag/d） daily for 84 too. The patient was a 85-year-old male with a history of ischemic heart disease. Seven years after initiation of treatment with AD, he was admitted with cardiac congestion. The total dose of AD was 528 g. Mild elevation of serum aminotransferase and hepatomegaly were present. Liver biopsy specimens revealed cirrhosis, and under electron microscopy numerous lysosomes with electron-dense, whorled, lamellar inclusions characteristic of a secondary phospholipidosis were observed. Initially, withdrawal of AD led to a slight improvement of serum aminotransferase levels, but unfortunately his general condition deteriorated and he died from complications of pneumonia and renal failure. Long-term administration of daily low doses of AD carries the risk of progression to irreversible liver injury. Therefore, periodic examination of liver function and/or liver biopsy is required for the management of patients receiving long-term treatment with AD.展开更多
ASYMMETRIC crying facies （ACF） is characterized by facial asymmetry only when crying. It may present as an exclusive symptom, or be con-comitant with other congenital malformations nd even some fatal birth defects. ...ASYMMETRIC crying facies （ACF） is characterized by facial asymmetry only when crying. It may present as an exclusive symptom, or be con-comitant with other congenital malformations nd even some fatal birth defects. Clinically, ACF is fea-tured by drooping of the intact corner of the mouth during crying, while the face appears symmetric at rest. The facial nerve function is symmetric, as determined by frowning, forehead wrinkling, eye closure, and nasolabial fold depth. When ACF alone is present, the cause is often compression of the mandibular branch of the facial nerve that is prob-ably due to birth trauma or abnormal fetal posture in utero. ACF with other congenital anomalies is usually caused by hypoplasia of the depressor anguli oris muscle （DAOM） on one side of the mouth.展开更多
Gastrointestinal stromal tumor (GIST) of the stomach was treated by endoscopic enucleation in five patients. They were three men and two woman, aged 36-56 years. Tumors located in the cardia were completely enucleated...Gastrointestinal stromal tumor (GIST) of the stomach was treated by endoscopic enucleation in five patients. They were three men and two woman, aged 36-56 years. Tumors located in the cardia were completely enucleated endoscopically without any serious complication. The largest diameter of removed tumors ranged from 1.2 to 2.5 cm. Histopathological diagnosis was GIST with low risk of malignancy (mitotic index < 5/50 high power field) in all cases. The patients were disease-free for 10.5-42.2 mo after endoscopic enucleation.展开更多
文摘[ Objective] The aim of this study was to provide a theoretical basis for the prevention and treatment of highly pathogenic porcine reproductive and respiratory syndrome （HP-PRRS）. [Method] Antigen location and histopathological observation in natural cases infected by highly pathogenic porcine reproductive and respiratory syndrome virus （HP-PRRSV） were analyzed by immunohistochemistry and H. E. staining. [Result] The virus antigen mainly existed in epithelial calls, and also a few in mecrophages, lymphocytes and brain nerve cells. [ Conclusion] The cell and tissue tropism of HP-PRRSV strain in natural cases is different from that of previous strains.
文摘Esophageal polyps are very rare,One case of giant fibrovascular polyp of the esophagus was described.The patient had symptoms of dysphagia and hematemesis.After examinations,the diagnosis of esophageal leiomyoma was made,In the process of thoracie exploration,esophageal polyp was removed,The pathological diagnosis postoperation was giant fibrovascular polyp of the esophagus associated with mucoid degeneration.
文摘Objective： To analyze the current situation of syphilis in the sexually transmitted diseases （STDs） clinic, from January 1994 to December 2002 was studied. Methods： All syphilis patients were confirmed by history, physical examination, dark-field microscopy of samples taken from the chancre or satellite lymph nodes,or positive serological tests. Results： From 1994 to 2002, there were 2067 cases of early syphilis, accounting for 20.01% （2067/10330） of all STD cases. The annual proportion of syphilis cases among all STD cases from 1994 to 2002 was 0.57%, 0.53%, 3.54%, 16.20%, 31.29%, 27.88%, 25.63%, 17.11%, 10.48%, respectively. Of 2067 syphilis patients,49.64% （1026/2067） were male and 50.36% （1041/2067） were female. 44.75% （925/2067） of all cases presented with primary syphilis, 44.90% （928/2067） with secondary syphilis, 9.77% （202/2067） with latent syphilis （without any conspicuous clinical signs or symptoms）, and 0.58% （12/2067） with congenital syphilis. The 30-39 year old cohort accounted for the largest proportion, at 37.68% （779/2067） of all syphilis cases. The 20-29 year old cohort also accounted for a large proportion, at 37.20% （769/2067） of all cases,followed by the 40-49 year old cohort, at 17.95% （371/2067）. Syphilis was most prevalent among the unemployed,self-employed laborers, and office workers in decreasing order. The majority of cases were graduates of either primary school, high school, or college. Of all syphilis cases, 87.86% （1816/2067） were married, and 12.14%（251/2067, including children） were unmarried. 76.78% （1587/2067） of all cases were acquired through extramarital intercourse. 14.03% （290/2067） of cases were infected by their spouses. 0.58% （12/2067） of cases were due to vertical transmission. 8.61% （178） of cases were acquired through indirect contact. Conclusion： The proportion of syphilis infection among all STDs remained stable from 1994 to 1995,quickly and dramatically increased from 1996 to 1999,and then gradually tapered down from 2000 to 2002. The incidence of congenital syphilis infections increased throughout the study period.
基金Supported by The National Scientific and Technological Program in the 11th "Five-Year Plan", the Grant number is 2006BAI02A08
文摘AIM:To investigate barriers to colorectal cancer(CRC) screening in a community population.METHODS:We conducted a community-based case-control study in an urban Chinese population by questionnaire.Cases were selected from those completing both a fecal occult blood test(FOBT) case and colonoscopy in a CRC screening program in 2004.Control groups were matched by gender, age group and community.Control 1 included those having a positive FOBT but refusing a colonoscopy.Control 2 included those who refused both an FOBT and colonoscopy.RESULTS:The impact of occupation on willingness to attend a colorectal screening program differed by gender.P for heterogeneity was 0.009 for case vs control group 1, 0.01 for case versus control group 2, and 0.80 for control group 1 vs 2.Poor awareness of CRC and its screening program, characteristics of screening tests, and lack of time affected the screening rate.Financial support, fear of pain and bowel preparation were barriers to a colonoscopy as a screening test.Eighty-two percent of control group 1 and 87.1% of control group 2 were willing attend if the colonoscopy was free, but only 56.3% and 53.1%, respectively, if it was self-paid.Multivariate odds ratios for case vs control group 1 were 0.10 among those unwilling to attend a free colonoscopy and 0.50 among those unwilling to attend a self-paid colonoscopy.CONCLUSION:Raising the public awareness of CRC and its screening, integrating CRC screening into the health care system, and using a painless colonoscopy would increase its screening rate.
基金Supported by Grants-in-Aid No. 16590289,16790211 and 16790212, and "Open Research Center" Project for Private Universities: Matching fund Subsidy (2004-2008), from Ministry of Education, Culture, Sports, Science and Technology, Japan
文摘The anti-arrhythmic agent amiodarone （AD） is associated with numerous adverse effects, but serious liver disease is rare. The improved safety of administration of daily low doses of AD has already been established and this regimen is used for long-term medication. Nevertheless, asymptomatic continuous liver injury by AD may increase the risk of step-wise progression of non-alcoholic fatty liver disease. We present an autopsy case of AD-induced liver cirrhosis in a patient who had been treated with a low dose of AD （200 rag/d） daily for 84 too. The patient was a 85-year-old male with a history of ischemic heart disease. Seven years after initiation of treatment with AD, he was admitted with cardiac congestion. The total dose of AD was 528 g. Mild elevation of serum aminotransferase and hepatomegaly were present. Liver biopsy specimens revealed cirrhosis, and under electron microscopy numerous lysosomes with electron-dense, whorled, lamellar inclusions characteristic of a secondary phospholipidosis were observed. Initially, withdrawal of AD led to a slight improvement of serum aminotransferase levels, but unfortunately his general condition deteriorated and he died from complications of pneumonia and renal failure. Long-term administration of daily low doses of AD carries the risk of progression to irreversible liver injury. Therefore, periodic examination of liver function and/or liver biopsy is required for the management of patients receiving long-term treatment with AD.
文摘ASYMMETRIC crying facies （ACF） is characterized by facial asymmetry only when crying. It may present as an exclusive symptom, or be con-comitant with other congenital malformations nd even some fatal birth defects. Clinically, ACF is fea-tured by drooping of the intact corner of the mouth during crying, while the face appears symmetric at rest. The facial nerve function is symmetric, as determined by frowning, forehead wrinkling, eye closure, and nasolabial fold depth. When ACF alone is present, the cause is often compression of the mandibular branch of the facial nerve that is prob-ably due to birth trauma or abnormal fetal posture in utero. ACF with other congenital anomalies is usually caused by hypoplasia of the depressor anguli oris muscle （DAOM） on one side of the mouth.
文摘Gastrointestinal stromal tumor (GIST) of the stomach was treated by endoscopic enucleation in five patients. They were three men and two woman, aged 36-56 years. Tumors located in the cardia were completely enucleated endoscopically without any serious complication. The largest diameter of removed tumors ranged from 1.2 to 2.5 cm. Histopathological diagnosis was GIST with low risk of malignancy (mitotic index < 5/50 high power field) in all cases. The patients were disease-free for 10.5-42.2 mo after endoscopic enucleation.
