To evaluate treatment patterns, including lack of treatment, among women diagnosed with cervical cancer in the United States. Using the National Cancer Insti- tute s (NCI s) Surveillance, Epidemiology, and End Res...To evaluate treatment patterns, including lack of treatment, among women diagnosed with cervical cancer in the United States. Using the National Cancer Insti- tute s (NCI s) Surveillance, Epidemiology, and End Results (SEER) program, we identified 13,715 women diagnosed with invasive cervical cancer between 1992 and 1999 and eligible for inclusion in the study. Nearly 9% of women diagnosed with invasive cervical cancer received no therapy for their disease. Lack of therapy was associated with a later stage of disease at diagnosis, older age, and unmarried status. More than 16% of women aged 65 and older with stage IIB/IV cervical cancer received no therapy for their disease. We must educate women diagnosed with cervical cancer and their families about the importance of treatment for potential cure and control of symptoms. We must identify and overcome obstacles that may prevent adherence to treatment recommendations. These may include comorbidity, access to cancer treatment, inability to pay for treatment, and inadequate social support.展开更多
To examine the prevalence of Human papillomavirus and Chlamydia trachomatis DN A in cervical samples among women with normal and abnormal cervical cytology fro m La Plata, Argentina. Two hundred and seventy-nine women...To examine the prevalence of Human papillomavirus and Chlamydia trachomatis DN A in cervical samples among women with normal and abnormal cervical cytology fro m La Plata, Argentina. Two hundred and seventy-nine women (200 with cervical ne oplasia or ICC and 79 women with normal cytology) provided cervical samples for the detection of HPV and C. trachomatis DNA by PCR-based assays. HPV DNA increa sed with the cervical lesion severity, ranging from 30%among women with normal cytology to 99-100%among women with HSIL or ICC. C. trachomatis DNA prevalence increased from low levels in women with normal cytology (11%) to 47%in those with HSIL, but was uncommon among ICC patients (20%)-. Among women with normal cytology, C. trachomatis prevalence was higher in HPV DNA positive (12.5%) tha n HPV DNA negative women (10.9%), but this difference was not significant. HPV prevalence in the general population is slightly higher than those reported for other developing countries. C. trachomatis DNA positivity was associated with a higher risk of both LSIL and HSIL lesions, but not with ICC.展开更多
文摘To evaluate treatment patterns, including lack of treatment, among women diagnosed with cervical cancer in the United States. Using the National Cancer Insti- tute s (NCI s) Surveillance, Epidemiology, and End Results (SEER) program, we identified 13,715 women diagnosed with invasive cervical cancer between 1992 and 1999 and eligible for inclusion in the study. Nearly 9% of women diagnosed with invasive cervical cancer received no therapy for their disease. Lack of therapy was associated with a later stage of disease at diagnosis, older age, and unmarried status. More than 16% of women aged 65 and older with stage IIB/IV cervical cancer received no therapy for their disease. We must educate women diagnosed with cervical cancer and their families about the importance of treatment for potential cure and control of symptoms. We must identify and overcome obstacles that may prevent adherence to treatment recommendations. These may include comorbidity, access to cancer treatment, inability to pay for treatment, and inadequate social support.
文摘To examine the prevalence of Human papillomavirus and Chlamydia trachomatis DN A in cervical samples among women with normal and abnormal cervical cytology fro m La Plata, Argentina. Two hundred and seventy-nine women (200 with cervical ne oplasia or ICC and 79 women with normal cytology) provided cervical samples for the detection of HPV and C. trachomatis DNA by PCR-based assays. HPV DNA increa sed with the cervical lesion severity, ranging from 30%among women with normal cytology to 99-100%among women with HSIL or ICC. C. trachomatis DNA prevalence increased from low levels in women with normal cytology (11%) to 47%in those with HSIL, but was uncommon among ICC patients (20%)-. Among women with normal cytology, C. trachomatis prevalence was higher in HPV DNA positive (12.5%) tha n HPV DNA negative women (10.9%), but this difference was not significant. HPV prevalence in the general population is slightly higher than those reported for other developing countries. C. trachomatis DNA positivity was associated with a higher risk of both LSIL and HSIL lesions, but not with ICC.
