目的:观察电针对便秘型肠易激综合征(IBS-C)模型大鼠抑郁样行为及血清IL-4的影响,探讨电针改善便秘型肠易激综合征抑郁样行为的机制。方法:采用冰水灌胃法制备IBS-C模型大鼠,造模成功后随机分为模型对照组、电针干预组、手针干预组、温...目的:观察电针对便秘型肠易激综合征(IBS-C)模型大鼠抑郁样行为及血清IL-4的影响,探讨电针改善便秘型肠易激综合征抑郁样行为的机制。方法:采用冰水灌胃法制备IBS-C模型大鼠,造模成功后随机分为模型对照组、电针干预组、手针干预组、温针干预组,另设空白对照组,每组5只。电针干预组、手针干预组、温针干预组分别给予“足三里”、“天枢”、“三阴交”组合电针、手针、温针等干预措施,持续7天,干预结束后评估各组大鼠的一般情况和体重变化,利用强迫游泳实验(FST)和糖水偏好实验(SPT)检测各组大鼠抑郁行为学表现,利用酶联免疫吸附试验(ELISA)检测各组大鼠血清中IL-4含量。结果:与空白对照组相比,模型组大鼠AWR评分显著升高(P P P P < 0.05),以电针组为著。结论:电针治疗可以显著改善IBS-C大鼠抑郁行为学表现,对于IBS-C康复治疗具有重要的临床意义,其作用机制可能与调节IBS-C模型大鼠炎症因子IL-4的水平有关。展开更多
目的:采用循证医学方法分析针刺治疗便秘型肠易激综合征(IBS-C)的经络取穴规律,为临床提供方案。方法:应用计算机检索截止至7月1日的文献,按照Cochrane系统文献质量评价的方法筛选随机对照研究方法文献,穴位出现采用频数和频率进行描述...目的:采用循证医学方法分析针刺治疗便秘型肠易激综合征(IBS-C)的经络取穴规律,为临床提供方案。方法:应用计算机检索截止至7月1日的文献,按照Cochrane系统文献质量评价的方法筛选随机对照研究方法文献,穴位出现采用频数和频率进行描述,运用SPSS26.0进行统计分析。结果:共有十二篇符合纳入标准的研究;十四经筛选统计总共出现19个穴位(前8个穴位依次为:足三里、天枢、上巨虚、三阴交、太冲、印堂、百会、中脘),分属11条经脉(足阳明胃经 > 任脉 > 足太阴脾经、督脉 > 足厥阴肝经、手少阳三焦经、手厥阴心包经、手阳明大肠经、足太阳膀胱经、手少阴心经、足少阳胆经)。结论:肠易激综合征便秘型针刺治疗穴位多选用募穴、下合穴、交会穴,常选用足阳明胃经、督脉、任脉、足太阴脾经、足厥阴肝经。Objective: To analyze the rule of meridian point selection in the treatment of constipated irritable bowel syndrome (IBS-C) by evidence-based medicine, and to provide clinical scheme. Methods: The literatures up to July 1 were searched by computer, and the literatures of randomized controlled studies were screened according to Cochrane systematic literature quality evaluation. The frequency of acupuncture points were described, and SPSS26.0 was used for statistical analysis. Results: A total of 12 studies met the inclusion criteria;After 14 screening, a total of 19 acupoints were found (the first 8 acupoints were: Zusanli, Tianshu, Shangjuxu, Sanyinjiao, Taichong, Yintang, Baihui, Zhongwan) belonging to 11 meridians (Zyangming Stomach Channel > Ren channel > Taiyin Spleen Channel, Du Channel > Jueyin Liver channel, Shaoyang Sanjiao Channel, Jueyin myocardium Channel, Yangming large intestine channel, Yang Sun Heart Channel, Shaoyang gallbladder channel). Conclusion: Mu point, Xiaihe point and Conifing point are the main acupuncture points for irritable bowel syndrome. The stomach channel, Du vein, Ren vein, Taiyin spleen channel and Jueyin liver channel of foot Yangming are often selected.展开更多
文摘目的:观察电针对便秘型肠易激综合征(IBS-C)模型大鼠抑郁样行为及血清IL-4的影响,探讨电针改善便秘型肠易激综合征抑郁样行为的机制。方法:采用冰水灌胃法制备IBS-C模型大鼠,造模成功后随机分为模型对照组、电针干预组、手针干预组、温针干预组,另设空白对照组,每组5只。电针干预组、手针干预组、温针干预组分别给予“足三里”、“天枢”、“三阴交”组合电针、手针、温针等干预措施,持续7天,干预结束后评估各组大鼠的一般情况和体重变化,利用强迫游泳实验(FST)和糖水偏好实验(SPT)检测各组大鼠抑郁行为学表现,利用酶联免疫吸附试验(ELISA)检测各组大鼠血清中IL-4含量。结果:与空白对照组相比,模型组大鼠AWR评分显著升高(P P P P < 0.05),以电针组为著。结论:电针治疗可以显著改善IBS-C大鼠抑郁行为学表现,对于IBS-C康复治疗具有重要的临床意义,其作用机制可能与调节IBS-C模型大鼠炎症因子IL-4的水平有关。
文摘目的:采用循证医学方法分析针刺治疗便秘型肠易激综合征(IBS-C)的经络取穴规律,为临床提供方案。方法:应用计算机检索截止至7月1日的文献,按照Cochrane系统文献质量评价的方法筛选随机对照研究方法文献,穴位出现采用频数和频率进行描述,运用SPSS26.0进行统计分析。结果:共有十二篇符合纳入标准的研究;十四经筛选统计总共出现19个穴位(前8个穴位依次为:足三里、天枢、上巨虚、三阴交、太冲、印堂、百会、中脘),分属11条经脉(足阳明胃经 > 任脉 > 足太阴脾经、督脉 > 足厥阴肝经、手少阳三焦经、手厥阴心包经、手阳明大肠经、足太阳膀胱经、手少阴心经、足少阳胆经)。结论:肠易激综合征便秘型针刺治疗穴位多选用募穴、下合穴、交会穴,常选用足阳明胃经、督脉、任脉、足太阴脾经、足厥阴肝经。Objective: To analyze the rule of meridian point selection in the treatment of constipated irritable bowel syndrome (IBS-C) by evidence-based medicine, and to provide clinical scheme. Methods: The literatures up to July 1 were searched by computer, and the literatures of randomized controlled studies were screened according to Cochrane systematic literature quality evaluation. The frequency of acupuncture points were described, and SPSS26.0 was used for statistical analysis. Results: A total of 12 studies met the inclusion criteria;After 14 screening, a total of 19 acupoints were found (the first 8 acupoints were: Zusanli, Tianshu, Shangjuxu, Sanyinjiao, Taichong, Yintang, Baihui, Zhongwan) belonging to 11 meridians (Zyangming Stomach Channel > Ren channel > Taiyin Spleen Channel, Du Channel > Jueyin Liver channel, Shaoyang Sanjiao Channel, Jueyin myocardium Channel, Yangming large intestine channel, Yang Sun Heart Channel, Shaoyang gallbladder channel). Conclusion: Mu point, Xiaihe point and Conifing point are the main acupuncture points for irritable bowel syndrome. The stomach channel, Du vein, Ren vein, Taiyin spleen channel and Jueyin liver channel of foot Yangming are often selected.
