《发光学报》成为美国《EI》收录源期刊

2010年3月25日,《发光学报》接到EI中国信息部通知:从2010年第1期起正式被《EI》(《工程索引》)收录为刊源。EI作为世界领先的应用科学和工程学在线信息服务提供者,是全世界最早的工程文摘来源,一直致力于为科学研究者和工程技术人员提供最专业、最实用的在线数据、知识等信息服务和支持。《发光学报》被EI收录,对加强我国发光学研究领域及论文作者开展更广泛的国内外交流,提升我国技术人员学术声誉具有积极的促进作用。

中国自然辩证法研究会举办科学道德宣讲教育活动

12月20日,中国自然辩证法研究会和北京科技大学文法学院联合主办的科学道德与学风建设宣讲教育活动暨北京科技大学"星期四人文讲座"第175讲在北京科技大学学术报告厅举行。中国自然辩证法研究会常务理事、中国科学院研究生院人文学院执行院长任定成教授为200余名北京科技大学学子作了题为《科学的精神气质与规范》的精彩讲座。

Enhanced CO oxidation over potassium-promoted Pt/Al_2O_3 catalysts:Kinetic and infrared spectroscopic study

A series of K-promoted Pt/Al2O3 catalysts were tested for CO oxidation. It was found that the addition of K significantly enhanced the activity. A detailed kinetic study showed that the activation energies of the K-containing catalysts were lower than those of the K-free ones, particularly for catalysts with high Pt contents （51.6 k）/mol for 0.42K-2.0Pt/Al2O3 and 6：3.6 kJ/mol for 2.0Pt/Al2O3 ）. The CO reaction orders were higher for the K-containing catalysts （about -0.2） than for the K-free ones （about -0.5）, with the former having much lower equilibrium constants for CO adsorption than the latter. In situ Fourier-transform infrared spectroscopy showed that surface CO desorption from the 0.42K-2.0Pt/Al2O3 catalyst was easier than from 2.0Pt/Al2O3. The promoting effect of K was therefore caused by weakening of the interactions between CO and surface Pt atoms. This decreased coverage of the catalyst with CO and facilitated competitive O2 chemisorption on the Pt surface, and significantly lowered the reaction barrier between chemisorbed CO and O2 species.

“非典”十年:伤痛与反思

许多人至今还记得,2003年的春天,北京的天气出奇的好,街头的月季花开得特别娇艳。"我刚刚从澳大利亚回国,踏进北京首都机场,眼前行色匆匆的人们大都戴着口罩,双眼透出逃难般的眼神。回到家的第二天,我就被告知要呆在家里自我隔离一周,好像我自己就是一个大病毒一样。"一位女孩如此回忆。她看到医护人员进入自己所在居民楼,他们身着白色、厚重的防护服,像一群太空人。这才意识到,在这个原本十分明媚的春天,北京的空气里飘浮着令人惶恐的病毒。渐渐地,"非典"(传染性非典型性肺炎)如潘多拉魔盒中的恶魔愈演愈烈。重疫区的中小学停课,高校采取封闭式管理,大型活动被取消或推迟,对出入疫区的长途旅客进行防疫检验,一时间人心惶惶,平日热闹的城市街道顿时空旷起来。2003年,"非典"在中国大陆留下了5327人感染、349人死亡的数字。这场严重的公共卫生危机改变了许多人的命运,也对政府信息公开和应急机制建设起到重大促进作用,成为中国公共卫生史上的一个转折点和里程碑。

Synergistic effect of all-trans-ret inoic acid and arsenic trioxide on growth inhibition and apoptosis in human hepatoma, breast cancer, and lung cancer cells in vitro

AIM： To investigate the effect of all-trans-retinoic acid （ATRA） on arsenic trioxide （As2O3）-induced apoptosis of human hepatoma, breast cancer, and lung cancer cells in an attempt to find a better combination therapy for solid tumors. METHODS： Human hepatoma cell lines HepG2, Hep3B, human breast cancer cell line MCF-7, and human lung adenocarcinoma cell line AGZY-83-a were treated with As203 together with ATRA. Cell survival fraction was determined by MTT assay, cell viability and apoptosis were measured by annexin V-fluorescein isothiocyanate （FITC） and PI staining, and intracellular glutathione （GSH） and glutathione-S-transferase （GST） activities were determined using commercial kits. RESULTS： Cytotoxicity of ATRA was low. ATRA （0.1, 1, and 10 μmol/L） could synergistically potentiate As2O3 to exert a dose-dependent inhibition of growth and to induce apoptosis in each of the cell lines. HepG2 and Hep3B with low intracellular GSH or GST activities were remarkably sensitive to As2O3 or As2O3＋ATRA, while AGZY-83-a with higher GSH or GST activities was less sensitive to As2O3 or As2O3＋ATRA. Treatment with 2 μmol/L As2O3 for 72 h significantly decreased intracellular GSH and GST levels in each of the cell lines, and 1 μmol/L ATRA alone reduced minimal intracellular GSH and GST levels. ATRA potentiated the effect of As2O3 on intracellular GSH levels, but intracellular GST levels were not significantly affected by the combination of As2O3 and ATRA for 72 h as compared to As2O3 alone.CONCLUSION： ATRA can strongly potentiate As2O3- induced growth-inhibition and apoptosis in each of the cell lines, and two drugs can produce a significant synergic effect. The sensitivity to As2O3 or As2O3＋ATRA is inversely proportional to intracellular GSH or GST levels in each of the cell lines. The GSH redox system may be the possible mechanism by which ATRA synergistically potentiates As203 to exert a dose-dependent inhibition of growth and to induce apoptosis. 2005 The WJG Press and Elsevier Inc. All rights reserved.

Rosiglitazone enhances fluorouracil-induced apoptosis of HT-29 cells by activating peroxisome proliferator-activated receptor γ

AIM： To examine whether and how rosiglitazone enhances apoptosis induced by fluorouracil in human colon cancer （HT-29） cells. METHODS： Human colon cancer HT-29 cells were cultured in vitro and treated with fluorouracil and/or rosiglitazone. Proliferation and growth of HT-29 cells were evaluated by MTF assay and trypan blue exclusion methods, respectively. The apoptosis of HT-29 cells was determined by acridine orange/ethidium bromide staining and flow cytometry using PI fluorescence staining. The expressions of peroxisome proliferator-activated receptor γ （PPARγ）, Bcl-2 and Bax in HT-29 cells were analyzed by Western blot. RESULTS： Although rosiglitazone at the concentration below 30 μmol/L for 72 h exerted almost no inhibitory effect on proliferation and growth of HT-29 cells, it could significantly enhance fluorouracil-induced HT-29 cell proliferation and growth inhibition. Furthermore, 10 μmol/L rosilitazone did not induce apoptosis of HT-29 cells but dramatically enhanced fluorouracil-induced apoptosis of HT-29 cells. However, rosiglitazone did not improve apoptosis induced by fluorouracil in HT-29 cells pretreated with GW9662, a PPARγ antagonist. Meanwhile, the expression of Bax and PPAR7 was upregulated, while the expression of Bcl-2 was down regulated in HT-29 cells treated with rosiglitazone in a time-dependent manner. However, the effect of rosiglitazone on Bcl-2 and Bax was blocked or diminished in the presence of GW9662. CONCLUSION： Rosiglitazone enhances fluorouracilinduced apoptosis of HT-29 cells by activating PPARγ.

Electrochemical recycling of Pd and Ag from simulated high-level liquid waste

For the recycling of Pd and Ag from high-level liquid waste(HLLW), the electrochemical behaviors of Pd and Ag in the simulated HNO_(3) solutions were investigated by cyclic voltammetry and potentiostatic deposition.Scanning electron microscopy(SEM) and X-ray diffraction(XRD) were used to-observe the deposits morphology and to evaluate their composition. The results indicate that the formation of NO_(2)^(-)electrodeposited. When Pd and Ag are electrodeposited together, more metals are gained in the same time, and the deposited Ag does not dissolve in this situation. The metals are electrodeposited completely at the potentials from -0.4 to -0.6 V(vs MSE) and the deposits contai-n Ag and PdHx. The electrodeposition of Pd can boost h-ydrogen evolution,and then the reaction between H;and NO_(2)^(-)is sped up, thereby lowering the concentration of NO_(2)^(-)and inhibiting the dissolution of Ag.

Synergistic effect of bromocriptine and tumor necrosis factor-a on reversing hepatoceiiuiar carcinoma multidrug resistance in nude mouse MDRl model of liver neoplasm

AIM： To investigate the effect of bromocripUne （BCT） and tumor necrosis factor-α ClNF-α） on hepatocellular carcinoma （HCC） multidrug resistance （MDR） in nude mouse HDR model of liver neoplasm. METHODS： Human hepatocarcinoma cell line HepG2t drug resistant hepatocarcinoma cell line HepG2/adriamycin （ADM） and hepatocarcinoma cell line transfected with TNF-α gene HepG2JADM/TNF were injected into the liver of nude mice via orthotopic implantation and MDR model of liver neoplasm in vivo was established （HepG2t ADM, TNF, BCT groups）. Among these groups, BCT group and TNF group were treated with BCT through gastric canal. Each group was divided into control group and chemotherapy group. Size and weight of the tumor were measured. Furthermore, tumor his^logical character and growth of the nude mice were observed and their chemosensitivity was tested. MDR-associated genes and proteins （MRP, LRP） of implanted tumors were detected by immunohistochemistry, reverse transcriptase polymerase chain reaction, and apoptosis rate of hepatocarcinoma cells was detected by TUNEL assay. RESULTS： The nude mouse model of each cell line was inoculated successfully. The tumor growth rate and weight were significantly different among groups. After chemotherapy, abdominal cavity tumor growth inhibition rate was higher in BCT group （67%） compared to ADM and TNF groups, and similar to HepG2group （54%）. MDRI and LRPmRNA could be detected in all groups, but TNF-α was detected only in TNF and BCT groups. Furthermore, MDR1 and LRP protein expression of tumors in TNF and BCT groups was low similar to HepG2 group. The apoptosis rate of hepatocarcinoma cells was much higher in BCT group than in other groups with TUNEL assay. CONCLUSION： BCT and TNF-a can reverse HCC MDR in nude mouse MDR1 model of liver neoplasm. 2005 The WJG Press and Elsevier Inc. All rights reserved

Substance P enhances the proliferation of rat anteriorpituitary cells in vitro

The undecapeptide substance P(SP) was shown to be intimately involved in both the structural and functional aspects of the anterior pituitary. Yet, in addition to its influences on hormonal secretion, SP may well possess more actions in this master gland. The present study was ftherefore aimed to investigate the effect of SP on the proliferation of rat anterior pituitary cells in primary culture. It was found that SP could dose-dependently increase the ineorporation of tritiated thymidine (3H-TdR)into cultured anterior pituitary cells. Other mammalian tachykinins such as neurokinin A and neurokinin B had similar effect but to varying degrees. The equipotent analogue of SP, Norleucine(11) -SP(Nle(11)-SP), also acted likewise, with its action antagonizable by spantide, a SP receptor blocker. To further characterize the nature of cells responsive to the challenge of SP, immunocytochemical staining against S-100 protein and some adenohypophyseal hormones was performed alone or plus autoradiography The results showed that the percentage of S-100 proteinimmunoreactive cells was apparently elevated by the addtion of Nle(11)-SP for 48 h, which indicates a preferential proliferation of folliculo-stellate cells under the regime. This was confirmed by increases in immunocytochemical or autoradiographical labelling indices of anterior pituitary cells treated similarly. Taken togethbr, these results reveal that the trophic action of SP observed previously in other tissues is also present at least in cultured rat anterior pituitary cells, with responding cells being predominantly folliculo-stellate cells as typified by S-100 proteinimmunoreactivity. Therefore, an intra-pituitary trophic action of SP in vivo could be anticipated.

An Investigation on Polypropylene Degradation in Supercritical Water Adding Benzoyl Peroxide

The effect of benzoyl peroxide （BPO） on polypropylene （PP） degradation in supercritical water was investigated with the aim of developing a process for recycling of waste plastics. A series of experiments with and without BPO were carried out at temperatures of 653 K and 673 K under pressure about 26 MPa for 30, 75 and 120 min respectively. Products were analyzed by an Ostward-type viscometer, gas chromatography and spectrometry （GC/MS） etc. The results indicated that mean molecular weight of the samples decreased greatly along with the time elapsing or with the temperature increasing, and PP was decomposed to Miphatic and cycloparaftinic hydrocarbons but a few benzenoid hydrocarbons. By comparing the experiments with and without BPO, it was made clear that BPO is an effective additive on PP degradation in supercritical water.

EFFECTS OF HBV preS AS A HUMORAL ENHANCER ON THE ABILITIES OF HCV E2 PROTEIN TO INDUCE IMMUNE RESPONSESIN THE DNA-IMMUNIZED MICE

Objective.To study whether the abilities of hepatitis C virus(HCV)E2 gene immunization to induce humoral and cellular immune responses to E2 protein were affected by hepatitis B virus(HBV)preS gene when they were fused in DNA-immunized mice.Methods.Mice were immunized with E2,preS-E2(preS gene was upstream of E2 gene),and E2-preS(preS gene was downstream of E2 gene)gene by their eukaryotic expression vectors,respectively.The anti-E2 or anti-preS antibodies were detected using the E2 and preS antigens.The cellular immune response to E2 pro-tein in immunized mice was presented by its survival time after injecting SP2/O myeloma cells expressing HCV E2 protein into the abdominal cavity.Results. Chimeric E2 and preS gene immunization can induce mice to develop anti-preS and anti-E2 antibodies.The number of the mice developing anti-E2 antibody and the antibody titers in preS-E2 gene-injected group were higher than those in E2-preS gene-immunized group.However,the mice injected with E2 gene did not develop the detectable anti-E2 antibodies until 12 weeks after DNA immunization.After the mice was injected with target cells,the average survival time of the mice in the group immunized with E2 gene alone was longer than that of the group injected with E2 gene fused with HBV preS and was significantly longer than that of the control(P< 0.05).Conclusion.HBV preS might be a humoral enhancer that can affect the abilities of HCV E2 protein to in-duce immune responses in DNA-immunized mice.

Growth-Promoting Effects of Liposome-Encapsulated Porcine Somatotropin in Mice

[ Objective] To study growth-promoting effects of liposome-encapsulated porcine somatotropin （pST） and its sustained-release effects in mice. [ Method] The mice were randomly divided into experimental groups and control group. The mice in the experimental groups were respective- ly administrated with pST and liposome-encapsulated pST via intraperitoneal injection, and those in the control group were administrated with saline. They were weighed on Day 7, 14 and 28, and the growth rate was calculated. [ Result] The growth of mice had significant difference between the experiment groups and control group （P 〈 0.05）, which indicated that the pST and liposome-encapsulated pST had growth-promoting effects in mice, and the liposome-encapsulated pST had sustained-release effects. [Condusion] The liposome-encapsulated pST can promote the growth of animal and its sustained-release peried is 7 d.

Effects of Written Corrective Feedback on College EFL Students’Writing Accuracy and Linguistic Knowledge Acquisition

Set at the interface between second language acquisition and second language writing,this study examines how different types of written corrective feedback(WCF)influence the writing accuracy of Chinese college students learning English as a Foreign Language(EFL)and whether WCF facilitates the students’grasp of the focused linguistic knowledge.The participants(n=60)were divided into direct correction group(n=20),indirect error-coding group(n=20)and metalinguistic explanation group(n=20).The three groups wrote four essays in two months and received WCF for the first three essays on the five targeted error types,namely tense errors,confusion of different forms of a word,word(articles,prepositions,etc.)missing,errors in subjectverb agreement and inappropriate verb-noun collocations.The results show that all three types of WCF improved students’writing accuracy but none of them had any statistical advantage,and the metalinguistic WCF was more effective than the other two forms in facilitating the acquisition of the targeted linguistic features.These results shed some light on teaching and consolidation of language points through writing in EFL contexts.

承钢公司27项职工先进操作法转化效益逾千万元

近日,河北钢铁集团承钢公司对职工自主创新27项先进操作法进行命名,并予以表彰。据悉,此次命名的先进操作法有19项是由职工团队完成,8项是由职工个人完成,年可转化效益愈千万元。2013年以来,承钢为进一步激发职工钻研技术的积极性,促进先进操作技术的推广应用,打造高技能的人才队伍,制定了《先进操作法管理办法》。

将软装设计引入课堂

本文拟通过软装设计的前景和背景分析,让学生了解软装设计的概念、方法、风格分类、设计流程等。将软装设计引入专业设计的课堂教学中,使老师在教学中强调软装的重要性,使学生在学习和完成作业的过程中,对空间硬装设计与软装设计统一思考,对空间按照一定的设计风格和效果进行设计,最终使得整个空间风格统一、和谐温馨、漂亮实用。

探析和谐式教育模式在Java教学中的应用创新

首先简要分析了当前Java课程教学中可能存在的问题和课程改革的必要性,然后介绍了和谐式教育模式的内涵,接着探讨了在Java课程教学中应用和谐式教学模式的具体措施。目的为推动Java课程的教育教学改革与发展服务。Java是当下最流行的一种面向对象程序设计语言,为适应社会需求,几乎所有院校都开设了这门课程。如何提高Java课程教与学的质量是摆在很多高校老师面前共同的问题。

统筹协调 全面推进 努力实现农电事业持续健康发展

1积极服务社会主义新农村建设,“户户通电”工程取得重要进展和显著成绩“户户通电”工程的实施,根本改善了通电地区的生产和生活条件,对这些地区的经济发展和农民生活水平提高,具有重要的促进作用;有利于党的政策和致富信息在偏远地区迅速传播,对农民群众思想观念的更新,培育造就社会主义新型农民,加强通电地区两个文明建设,缩小城乡差距。

在当代艺术生产与文化旅游产业高层论坛上的致辞

(2012年7月7日)尊敬的邹部长,各位专家学者,女士们、先生们:大家下午好!首先,我代表成都文化旅游发展集团,向莅临成都参加今天论坛的各位嘉宾,表示热烈的欢迎和诚挚的感谢!今天论坛的主题,是"当代艺术生产与文化旅游产业发展"。进入21世纪以来,文化与经济的融合已成为全球发展的重要趋势和时代潮流。近年来。

浅谈高中英语教学中的情境创设方法

随着我们国家英语课程不断改革,对于新课改后的英语课程的深入和研究,能否提升高中英语教学质量的关键所在就是加强针对高中英语教学的策略进行一系列的研究和实施。其中就有关于情境创设的方法,情境创设方法如何运用到高中的英语教学中。