It aims to investigate the protective effects of sodium hyaluronate,panthenol,Portulaca oleracea L.and Calendula officinalis L.on hyperosmotic dehydration-induced injury of human immortalized keratinocytes(HaCaT).The ...It aims to investigate the protective effects of sodium hyaluronate,panthenol,Portulaca oleracea L.and Calendula officinalis L.on hyperosmotic dehydration-induced injury of human immortalized keratinocytes(HaCaT).The safety mass concentrations of four raw materials were screened by detecting cell viability,and the secretion of hyaluronic acid(HA)was determined using the ELISA method.The expression of HaCaT barrier function related genes(OVOL1,EREG,TGM1,TGM2,IVL,IRF6,THBS1,CASP14)was detected at the mRNA level to explore the regulatory effect of four raw materials on these genes.The results demonstrate that pretreatment with the four kinds of raw materials could increase the cell viability after hyperosmotic dehydration,promote the secretion of HA,and improve the expression of barrier function related genes after hyperosmotic dehydration,among which panthenol and Calendula officinalis L.are better.The results show that the four raw materials have a certain protective effect on the hyperosmotic dehydration cell model,which provides data support for its application in cosmetics.展开更多
In order to simulate the evolution of affordable housing land use a dynamic model that combines cellular automata CA and a multi-agent system MAS is established.This paper aims to utilize the approach of decision fact...In order to simulate the evolution of affordable housing land use a dynamic model that combines cellular automata CA and a multi-agent system MAS is established.This paper aims to utilize the approach of decision factors on site selection of affordable housing through a literature review to construct a hierarchy model of those factors identifying the weight of each factor by an analytic hierarchy process AHP .Based on those weight factors the CA-MAS model is designed. Nanjing city is taken as an example to verify the feasibility of the model.The results show that the CA-MAS model is pragmatic and effective in simulating evolution of affordable housing land use which also promotes the fundamental understanding and perception of the development of affordable housing and urbanization.展开更多
Comparative Vision article from Social Security Intemational, discusses the need for international comparison focuses on the typical characteristics of the United Kingdom, Germany, the United States established the de...Comparative Vision article from Social Security Intemational, discusses the need for international comparison focuses on the typical characteristics of the United Kingdom, Germany, the United States established the developed capitalist countries and emerging East Asian countries social security model, and on this basis, summed up the country should learn fi'om each experience, its essence, as I used to promote the construction of China's social security system towards healthy and sustainable direction.展开更多
The Macedonian economy gets out relatively little hurt by the global economic crisis not facing with financial crisis, the recession was short-lived, and social crisis emerged in modest sizes. However, the global cris...The Macedonian economy gets out relatively little hurt by the global economic crisis not facing with financial crisis, the recession was short-lived, and social crisis emerged in modest sizes. However, the global crisis revealed the major weaknesses of the economic model which was implemented. It turned out that the Macedonian economy is very dependent on the performance of only a few sectors and movements on the prices of its most important export and import products, and that the scope of supply and demand for domestic goods and services is small. These lectures from the economic crisis posed by the need to create a new model for country economic development in the future. The application of historical, statistical, analytical and comparative method shows that Macedonia should exercise other holistic approach in the remodeling of their economy. This means that, besides keeping macroeconomic and financial policy in the future the Macedonian government should act more vigorously in the direction of creating new jobs and provide greater social security. The economic model that we propose in this paper recommends it be done by encouraging small and medium enterprises, diversification of production, encouraging domestic investments, developing human capital, improving infrastructure, encouraging exports and harmonization the macroeconomic instruments. The application of this model will result in increasing investments, industrial production and exports, increasing the competitiveness of domestic products, reducing the trade deficit and maintaining the macroeconomic stability. The general conclusion of the paper is that application of the proposed economic model should lead to realization of two most important goals: achieving lasting, sustainable and significantly higher rates of economic growth and reducing the high rate of unemployment in the country.展开更多
In this paper we investigate the possibility of pareto improving social security reforms within a framework of endogenous growth. Belan et al. proposed a transition from a pay-as-you-go(PAYG) pension system to a syste...In this paper we investigate the possibility of pareto improving social security reforms within a framework of endogenous growth. Belan et al. proposed a transition from a pay-as-you-go(PAYG) pension system to a system of saving-subsidization. We follow this approach and prove that a pareto improving conversion from the PAYG system to a fully funded system is possible and discuss the problem of implementing the transition to the fully funded system.展开更多
Low Earth Orbit (LEO) satellites networks can provide multimedia service and plays an increasingly important role in the exploitation of space. However, one of the challenges in LEO satellites networks is that the s...Low Earth Orbit (LEO) satellites networks can provide multimedia service and plays an increasingly important role in the exploitation of space. However, one of the challenges in LEO satellites networks is that the services are suffered from high symbol error, limited storage space and limited available energy. To analyze the performance of the service in LEO satellites networks, a model, based on differential game, is proposed for satisfying the QoS requirements of multimedia applications. The controller of our model is the transmitting rate and the object is to maximize the payoff depending on the error symbol rate, the available energy, the bandwidth and the process ability so as to guarantee the QoS service. In order to solve our built model, we use the Bellman theorem to make formulas on the trance of the optimal transmitting rate. Furthermore, simulation results verify that the service can be maximized by using our derived transmitting rate trance.展开更多
This paper uses SWOT analysis, feasibility analysis of integration of urban and rural residents in China, including the overall analysis of the urban and rural integration China internal conditions, mainly for its ove...This paper uses SWOT analysis, feasibility analysis of integration of urban and rural residents in China, including the overall analysis of the urban and rural integration China internal conditions, mainly for its overall advantages and disadvantages are analyzed; and the external environment, the system is mainly to raise the opportunities and threats were analyzed; in these. The external conditions are analyzed based on the construction of SWOT strategic matrix, found the advantages and disadvantages of the reform process of the integration of urban and rural subsistence allowances system in coexist, opportunities outweigh the challenges, so China's overall urban and rural integration construction is feasible.展开更多
AIM:To evaluate the impact of surgical volume on nationwide hospital mortality after pancreaticoduodenectomy(PD) for periampullary tumors in South Korea.METHODS:Periampullary cancer patients who underwent PD between 2...AIM:To evaluate the impact of surgical volume on nationwide hospital mortality after pancreaticoduodenectomy(PD) for periampullary tumors in South Korea.METHODS:Periampullary cancer patients who underwent PD between 2005 and 2008 were analyzed from the database of the Health Insurance Review and Assessment Service of South Korea.A total of 126 hospitals were divided into 5 categories,each similar in terms of surgical volume for each category.We used hospital mortality as a quality indicator,which was defined as death during the hospital stay for PD,and calculated adjusted mortality through multivariate logistic models using several confounder variables.RESULTS:A total of eligible 4975 patients were enrolled in this study.Average annual surgical volume of hospitals was markedly varied,ranging from 215 PDs in the very-high-volume hospital to < 10 PDs in the verylow-volume hospitals.Admission route,type of medical security,and type of operation were significantly different by surgical volume.The overall hospital mortality was 2.1% and the observed hospital mortality by surgical volume showed statistical difference.Surgical volume,age,and type of operation were independent risk factors for hospital death,and adjusted hospital mortality showed a similar difference between hospitals with observed mortality.The result of the HosmerLemeshow test was 5.76(P = 0.674),indicating an acceptable appropriateness of our regression model.CONCLUSION:The higher-volume hospitals showed lower hospital mortality than the lower-volume hospitals after PD in South Korea,which were clarified through the nationwide database.展开更多
In this paper, the authors present a modelling activity developed from a thematic project in the models and mathematical modelling class of the professional master's degree program in mathematics education at the Fed...In this paper, the authors present a modelling activity developed from a thematic project in the models and mathematical modelling class of the professional master's degree program in mathematics education at the Federal University of Ouro Preto. The students enrolled in the class chose to study the theme Brazilian Public Politics. After several debates regarding the theme, the students were separated into three groups and each group chose a subtheme to study. The themes were IDH (index of human development), minimum wage and social security. As an example, a description of the thematic project about the minimum wage in Brazil is presented. The principal results obtained in the study of this theme include a discussion about the potentialities of the theme as a classroom activity in different levels of schooling. As an educational activity, the thematic project demonstrated itself to be greatly relevant, since not only did it provide the learning possibility of mathematics related to the issues studied, but also promoted various discussions regarding the theme, which, in our conception, contributes to the social-critical development of the students. Finally, from the point of view of applied mathematics and mathematics education, the development of a modelling activity from thematic projects showed itself to be a good source of researches.展开更多
文摘It aims to investigate the protective effects of sodium hyaluronate,panthenol,Portulaca oleracea L.and Calendula officinalis L.on hyperosmotic dehydration-induced injury of human immortalized keratinocytes(HaCaT).The safety mass concentrations of four raw materials were screened by detecting cell viability,and the secretion of hyaluronic acid(HA)was determined using the ELISA method.The expression of HaCaT barrier function related genes(OVOL1,EREG,TGM1,TGM2,IVL,IRF6,THBS1,CASP14)was detected at the mRNA level to explore the regulatory effect of four raw materials on these genes.The results demonstrate that pretreatment with the four kinds of raw materials could increase the cell viability after hyperosmotic dehydration,promote the secretion of HA,and improve the expression of barrier function related genes after hyperosmotic dehydration,among which panthenol and Calendula officinalis L.are better.The results show that the four raw materials have a certain protective effect on the hyperosmotic dehydration cell model,which provides data support for its application in cosmetics.
基金The National Social Science Foundation of China(No.14AJY013)the Scientific Innovation Research of College Graduates in Jiangsu Province(No.CXLX13_126)
文摘In order to simulate the evolution of affordable housing land use a dynamic model that combines cellular automata CA and a multi-agent system MAS is established.This paper aims to utilize the approach of decision factors on site selection of affordable housing through a literature review to construct a hierarchy model of those factors identifying the weight of each factor by an analytic hierarchy process AHP .Based on those weight factors the CA-MAS model is designed. Nanjing city is taken as an example to verify the feasibility of the model.The results show that the CA-MAS model is pragmatic and effective in simulating evolution of affordable housing land use which also promotes the fundamental understanding and perception of the development of affordable housing and urbanization.
文摘Comparative Vision article from Social Security Intemational, discusses the need for international comparison focuses on the typical characteristics of the United Kingdom, Germany, the United States established the developed capitalist countries and emerging East Asian countries social security model, and on this basis, summed up the country should learn fi'om each experience, its essence, as I used to promote the construction of China's social security system towards healthy and sustainable direction.
文摘The Macedonian economy gets out relatively little hurt by the global economic crisis not facing with financial crisis, the recession was short-lived, and social crisis emerged in modest sizes. However, the global crisis revealed the major weaknesses of the economic model which was implemented. It turned out that the Macedonian economy is very dependent on the performance of only a few sectors and movements on the prices of its most important export and import products, and that the scope of supply and demand for domestic goods and services is small. These lectures from the economic crisis posed by the need to create a new model for country economic development in the future. The application of historical, statistical, analytical and comparative method shows that Macedonia should exercise other holistic approach in the remodeling of their economy. This means that, besides keeping macroeconomic and financial policy in the future the Macedonian government should act more vigorously in the direction of creating new jobs and provide greater social security. The economic model that we propose in this paper recommends it be done by encouraging small and medium enterprises, diversification of production, encouraging domestic investments, developing human capital, improving infrastructure, encouraging exports and harmonization the macroeconomic instruments. The application of this model will result in increasing investments, industrial production and exports, increasing the competitiveness of domestic products, reducing the trade deficit and maintaining the macroeconomic stability. The general conclusion of the paper is that application of the proposed economic model should lead to realization of two most important goals: achieving lasting, sustainable and significantly higher rates of economic growth and reducing the high rate of unemployment in the country.
文摘In this paper we investigate the possibility of pareto improving social security reforms within a framework of endogenous growth. Belan et al. proposed a transition from a pay-as-you-go(PAYG) pension system to a system of saving-subsidization. We follow this approach and prove that a pareto improving conversion from the PAYG system to a fully funded system is possible and discuss the problem of implementing the transition to the fully funded system.
基金National Science Foundation Project of P.R.China,China Postdoctoral Science Foundation
文摘Low Earth Orbit (LEO) satellites networks can provide multimedia service and plays an increasingly important role in the exploitation of space. However, one of the challenges in LEO satellites networks is that the services are suffered from high symbol error, limited storage space and limited available energy. To analyze the performance of the service in LEO satellites networks, a model, based on differential game, is proposed for satisfying the QoS requirements of multimedia applications. The controller of our model is the transmitting rate and the object is to maximize the payoff depending on the error symbol rate, the available energy, the bandwidth and the process ability so as to guarantee the QoS service. In order to solve our built model, we use the Bellman theorem to make formulas on the trance of the optimal transmitting rate. Furthermore, simulation results verify that the service can be maximized by using our derived transmitting rate trance.
文摘This paper uses SWOT analysis, feasibility analysis of integration of urban and rural residents in China, including the overall analysis of the urban and rural integration China internal conditions, mainly for its overall advantages and disadvantages are analyzed; and the external environment, the system is mainly to raise the opportunities and threats were analyzed; in these. The external conditions are analyzed based on the construction of SWOT strategic matrix, found the advantages and disadvantages of the reform process of the integration of urban and rural subsistence allowances system in coexist, opportunities outweigh the challenges, so China's overall urban and rural integration construction is feasible.
文摘AIM:To evaluate the impact of surgical volume on nationwide hospital mortality after pancreaticoduodenectomy(PD) for periampullary tumors in South Korea.METHODS:Periampullary cancer patients who underwent PD between 2005 and 2008 were analyzed from the database of the Health Insurance Review and Assessment Service of South Korea.A total of 126 hospitals were divided into 5 categories,each similar in terms of surgical volume for each category.We used hospital mortality as a quality indicator,which was defined as death during the hospital stay for PD,and calculated adjusted mortality through multivariate logistic models using several confounder variables.RESULTS:A total of eligible 4975 patients were enrolled in this study.Average annual surgical volume of hospitals was markedly varied,ranging from 215 PDs in the very-high-volume hospital to < 10 PDs in the verylow-volume hospitals.Admission route,type of medical security,and type of operation were significantly different by surgical volume.The overall hospital mortality was 2.1% and the observed hospital mortality by surgical volume showed statistical difference.Surgical volume,age,and type of operation were independent risk factors for hospital death,and adjusted hospital mortality showed a similar difference between hospitals with observed mortality.The result of the HosmerLemeshow test was 5.76(P = 0.674),indicating an acceptable appropriateness of our regression model.CONCLUSION:The higher-volume hospitals showed lower hospital mortality than the lower-volume hospitals after PD in South Korea,which were clarified through the nationwide database.
文摘In this paper, the authors present a modelling activity developed from a thematic project in the models and mathematical modelling class of the professional master's degree program in mathematics education at the Federal University of Ouro Preto. The students enrolled in the class chose to study the theme Brazilian Public Politics. After several debates regarding the theme, the students were separated into three groups and each group chose a subtheme to study. The themes were IDH (index of human development), minimum wage and social security. As an example, a description of the thematic project about the minimum wage in Brazil is presented. The principal results obtained in the study of this theme include a discussion about the potentialities of the theme as a classroom activity in different levels of schooling. As an educational activity, the thematic project demonstrated itself to be greatly relevant, since not only did it provide the learning possibility of mathematics related to the issues studied, but also promoted various discussions regarding the theme, which, in our conception, contributes to the social-critical development of the students. Finally, from the point of view of applied mathematics and mathematics education, the development of a modelling activity from thematic projects showed itself to be a good source of researches.