目的:提出一种相位式呼吸门控放疗中门控窗口的选择方法。方法:采用数字表法随机选取某院已完成基于实时位置管理(real position management,RPM)系统的相位式呼吸门控放疗的38例患者。针对每个患者的参考呼吸波形,分别计算所有可选的10...目的:提出一种相位式呼吸门控放疗中门控窗口的选择方法。方法:采用数字表法随机选取某院已完成基于实时位置管理(real position management,RPM)系统的相位式呼吸门控放疗的38例患者。针对每个患者的参考呼吸波形,分别计算所有可选的100(10×10)个窗口内的呼吸信号标准差,作为衡量该窗口内呼吸运动稳定性的指标。在100个可选窗口中,将与临床所选窗口占空比相同但呼吸信号标准差最小的窗口作为建议窗口。比较并分析38例患者的临床窗口和基于该方法选择的建议窗口之间的呼吸信号标准差差异,并进行配对样本t检验。结果:38例患者中,临床窗口的呼吸信号标准差为(0.114±0.050)cm,建议窗口的呼吸信号标准差为(0.108±0.049)cm,二者相比有统计学差异(P=0.009)。27例患者的建议窗口与临床窗口一致,其余11例患者的建议窗口与临床窗口相比呼吸信号标准差有所减小(窗口内呼吸运动稳定性提高),其中1例下降幅度超过30%,8例下降幅度在5%~30%,2例下降幅度在5%以内。结论:在相位式呼吸门控放疗中,基于窗口内的呼吸信号标准差选择门控窗口的方法可以保证和提高临床所选门控窗口的质量。展开更多
A method was demonstrated based on Infomax independent component analysis(Infomax ICA) for automatically extracting auditory P300 signals within several trials. A signaling equilibrium algorithm was proposed to enhanc...A method was demonstrated based on Infomax independent component analysis(Infomax ICA) for automatically extracting auditory P300 signals within several trials. A signaling equilibrium algorithm was proposed to enhance the effectiveness of the Infomax ICA decomposition. After the mixed signal was decomposed by Infomax ICA, the independent component(IC) used in auditory P300 reconstruction was automatically chosen by using the standard deviation of the fixed temporal pattern. And the result of auditory P300 was reconstructed using the selected ICs. The experimental results show that the auditory P300 can be detected automatically within five trials. The Pearson correlation coefficient between the standard signal and the signal detected using the proposed method is significantly greater than that between the standard signal and the signal detected using the average method within five trials. The wave pattern result obtained using the proposed algorithm is better and more similar to the standard signal than that obtained by the average method for the same number of trials. Therefore, the proposed method can automatically detect the effective auditory P300 within several trials.展开更多
The aim of this study is to identify the functions and states of the brains according to the values of the complexity measure of the EEG signals. The EEG signals of 30 normal samples and 30 patient samples are collect...The aim of this study is to identify the functions and states of the brains according to the values of the complexity measure of the EEG signals. The EEG signals of 30 normal samples and 30 patient samples are collected. Based on the preprocessing for the raw data, a computational program for complexity measure is compiled and the complexity measures of all samples are calculated. The mean value and standard error of complexity measure of control group is as 0.33 and 0.10, and the normal group is as 0.53 and 0.08. When the confidence degree is 0.05, the confidence interval of the normal population mean of complexity measures for the control group is (0.2871,0.3652), and (0.4944,0.5552) for the normal group. The statistic results show that the normal samples and patient samples can be clearly distinguished by the value of measures. In clinical medicine, the results can be used to be a reference to evaluate the function or state, to diagnose disease, to monitor the rehabilitation progress of the brain.展开更多
In order to measure the flow velocity of carbon particle suspension perpendicular to the receiving axis of ultrasound transducer, the standard deviation of photoacoustic Doppler frequency spectrum is used to estimate ...In order to measure the flow velocity of carbon particle suspension perpendicular to the receiving axis of ultrasound transducer, the standard deviation of photoacoustic Doppler frequency spectrum is used to estimate the bandwidth broadening, and the spectrum standard deviation is calculated by an auto-correlation method. A 532 nm pulsed laser with the repetition rate of 20 Hz is used as a pumping source to generate photoacoustic signal. The photoacoustic signals are detected using a focused PZT ultrasound transducer with the central frequency of 10 MHz. The suspension of carbon particles is driven by a syringe pump. The complex photoacoustic signal is calculated by Hilbert transformation from time domain signal before auto-correlation. The standard deviation of the Doppler bandwidth broadening is calculated by averaging the auto-correlation results of several individual A scans. The feasibility of the proposed method is demonstrated by measuring the spectrum standard deviation of the transversal carbon particle flow from 5.0 mm/s to 8.4 mrn/s. The experimental results show that the auto-correlation result is approximately linearly distributed within the measuring range.展开更多
文摘目的:提出一种相位式呼吸门控放疗中门控窗口的选择方法。方法:采用数字表法随机选取某院已完成基于实时位置管理(real position management,RPM)系统的相位式呼吸门控放疗的38例患者。针对每个患者的参考呼吸波形,分别计算所有可选的100(10×10)个窗口内的呼吸信号标准差,作为衡量该窗口内呼吸运动稳定性的指标。在100个可选窗口中,将与临床所选窗口占空比相同但呼吸信号标准差最小的窗口作为建议窗口。比较并分析38例患者的临床窗口和基于该方法选择的建议窗口之间的呼吸信号标准差差异,并进行配对样本t检验。结果:38例患者中,临床窗口的呼吸信号标准差为(0.114±0.050)cm,建议窗口的呼吸信号标准差为(0.108±0.049)cm,二者相比有统计学差异(P=0.009)。27例患者的建议窗口与临床窗口一致,其余11例患者的建议窗口与临床窗口相比呼吸信号标准差有所减小(窗口内呼吸运动稳定性提高),其中1例下降幅度超过30%,8例下降幅度在5%~30%,2例下降幅度在5%以内。结论:在相位式呼吸门控放疗中,基于窗口内的呼吸信号标准差选择门控窗口的方法可以保证和提高临床所选门控窗口的质量。
基金Projects(81460273,61265006)supported by the National Natural Science Foundation of ChinaProject(2013GXNSFAA019325)supported by Guangxi Natural Science Foundation,ChinaProject(1348020-10)supported by Guangxi Science and Technology Program,China
文摘A method was demonstrated based on Infomax independent component analysis(Infomax ICA) for automatically extracting auditory P300 signals within several trials. A signaling equilibrium algorithm was proposed to enhance the effectiveness of the Infomax ICA decomposition. After the mixed signal was decomposed by Infomax ICA, the independent component(IC) used in auditory P300 reconstruction was automatically chosen by using the standard deviation of the fixed temporal pattern. And the result of auditory P300 was reconstructed using the selected ICs. The experimental results show that the auditory P300 can be detected automatically within five trials. The Pearson correlation coefficient between the standard signal and the signal detected using the proposed method is significantly greater than that between the standard signal and the signal detected using the average method within five trials. The wave pattern result obtained using the proposed algorithm is better and more similar to the standard signal than that obtained by the average method for the same number of trials. Therefore, the proposed method can automatically detect the effective auditory P300 within several trials.
基金International Joint Research Program from the Ministry of Science and Technology of Chinagrant number:20070667+1 种基金Education Commission of Chongqing of Chinagrant number:KJ081209
文摘The aim of this study is to identify the functions and states of the brains according to the values of the complexity measure of the EEG signals. The EEG signals of 30 normal samples and 30 patient samples are collected. Based on the preprocessing for the raw data, a computational program for complexity measure is compiled and the complexity measures of all samples are calculated. The mean value and standard error of complexity measure of control group is as 0.33 and 0.10, and the normal group is as 0.53 and 0.08. When the confidence degree is 0.05, the confidence interval of the normal population mean of complexity measures for the control group is (0.2871,0.3652), and (0.4944,0.5552) for the normal group. The statistic results show that the normal samples and patient samples can be clearly distinguished by the value of measures. In clinical medicine, the results can be used to be a reference to evaluate the function or state, to diagnose disease, to monitor the rehabilitation progress of the brain.
基金supported by the Joint Funds of the National Natural Science Foundation of China(No.U1204612)the Natural Science Foundation of He’nan Educational Committee(No.13A416180)
文摘In order to measure the flow velocity of carbon particle suspension perpendicular to the receiving axis of ultrasound transducer, the standard deviation of photoacoustic Doppler frequency spectrum is used to estimate the bandwidth broadening, and the spectrum standard deviation is calculated by an auto-correlation method. A 532 nm pulsed laser with the repetition rate of 20 Hz is used as a pumping source to generate photoacoustic signal. The photoacoustic signals are detected using a focused PZT ultrasound transducer with the central frequency of 10 MHz. The suspension of carbon particles is driven by a syringe pump. The complex photoacoustic signal is calculated by Hilbert transformation from time domain signal before auto-correlation. The standard deviation of the Doppler bandwidth broadening is calculated by averaging the auto-correlation results of several individual A scans. The feasibility of the proposed method is demonstrated by measuring the spectrum standard deviation of the transversal carbon particle flow from 5.0 mm/s to 8.4 mrn/s. The experimental results show that the auto-correlation result is approximately linearly distributed within the measuring range.