Objective Brachial-ankle pulse wave velocity (baPWV) is widely used as a simple noninvasive measure of arterial softness. The aim of this study was to evaluate the usefulness of baPWV as a predictor of the carotid a...Objective Brachial-ankle pulse wave velocity (baPWV) is widely used as a simple noninvasive measure of arterial softness. The aim of this study was to evaluate the usefulness of baPWV as a predictor of the carotid artery atherosclerosis in the elderly. Methods A total of 721 elderly participants (mean ~ SD age, 70.3 -4- 5.6years) were enrolled in the current study. All participant underwent both baPWV measurement and B-mode ultrasound for the intima-media thickness. Carotid atherosclerosis (CAS) was defined as the present of carotid plaque or and/or intima media thickness for at least 1.1 mm. Results A multivariate logistic regression analysis reveals that age, sex, brachial-ankle pulse wave velocity, smoking and LDL-C level showed a significant correlation with the presence of CAS. The odds ratios of CAS associated with a 500cm/s increase of brachial-ankle pulse wave velocity were 2.378 [95% confidence interval, 1.36 to 4.00, P〈0.05], 3.733 [95% confidence interval, 1.729 to 8.058, P〈0.01], 4.438 [95% confidence interval, 1.659 to 11.803, P〈0.01]. The baPWV significantly correlated with IMT by bivariate correlation analysis (r=-0.39; p=0.001). After adjusting for factors influencing, baPWV all the same correlated with IMT (r=-0.35; p=0.001).Conclusion These results indicate that brachial-ankle PWV is an independent predictor of CAS in the elderly.It also means that the direct measurement of arterial stiffness by this simple method may be of great help for the evaluation of carotid artherosclerosis, at least in the elderly展开更多
A model of using binomial tree pricing formulae in a fuzzy market is proposed. In the fuzzy market, a price interval can be got according to the belief degree. The rule for the reasonability of the price interval is p...A model of using binomial tree pricing formulae in a fuzzy market is proposed. In the fuzzy market, a price interval can be got according to the belief degree. The rule for the reasonability of the price interval is proposed. The explicit expression of the interval is discussed in some special settings.展开更多
In this article, the true model of sizep is considered. The importance of the independent variables will be studied. The model by dropping independent variable one at a time is called a reduced model, and the size of ...In this article, the true model of sizep is considered. The importance of the independent variables will be studied. The model by dropping independent variable one at a time is called a reduced model, and the size of the model is p-1. The non-centrality quantity is employed to measure the strength of influence on the true model for the independent variable dropped. The larger influence is defined to be more important in the true model. In this article, the goal is ranking the importance of the independent variables to study the structure of the models. It is important in the practical application. The confidence interval approach is used to rank the degrees of the influence of the independent variables in linear models and achieve the goal. An illustrative example is given, and the modeling procedure is studied to check the assumptions step by step in this example to make sure the assumptions satisfied in the true model. As a result, the proposed method can be used efficiently.展开更多
文摘Objective Brachial-ankle pulse wave velocity (baPWV) is widely used as a simple noninvasive measure of arterial softness. The aim of this study was to evaluate the usefulness of baPWV as a predictor of the carotid artery atherosclerosis in the elderly. Methods A total of 721 elderly participants (mean ~ SD age, 70.3 -4- 5.6years) were enrolled in the current study. All participant underwent both baPWV measurement and B-mode ultrasound for the intima-media thickness. Carotid atherosclerosis (CAS) was defined as the present of carotid plaque or and/or intima media thickness for at least 1.1 mm. Results A multivariate logistic regression analysis reveals that age, sex, brachial-ankle pulse wave velocity, smoking and LDL-C level showed a significant correlation with the presence of CAS. The odds ratios of CAS associated with a 500cm/s increase of brachial-ankle pulse wave velocity were 2.378 [95% confidence interval, 1.36 to 4.00, P〈0.05], 3.733 [95% confidence interval, 1.729 to 8.058, P〈0.01], 4.438 [95% confidence interval, 1.659 to 11.803, P〈0.01]. The baPWV significantly correlated with IMT by bivariate correlation analysis (r=-0.39; p=0.001). After adjusting for factors influencing, baPWV all the same correlated with IMT (r=-0.35; p=0.001).Conclusion These results indicate that brachial-ankle PWV is an independent predictor of CAS in the elderly.It also means that the direct measurement of arterial stiffness by this simple method may be of great help for the evaluation of carotid artherosclerosis, at least in the elderly
文摘A model of using binomial tree pricing formulae in a fuzzy market is proposed. In the fuzzy market, a price interval can be got according to the belief degree. The rule for the reasonability of the price interval is proposed. The explicit expression of the interval is discussed in some special settings.
文摘In this article, the true model of sizep is considered. The importance of the independent variables will be studied. The model by dropping independent variable one at a time is called a reduced model, and the size of the model is p-1. The non-centrality quantity is employed to measure the strength of influence on the true model for the independent variable dropped. The larger influence is defined to be more important in the true model. In this article, the goal is ranking the importance of the independent variables to study the structure of the models. It is important in the practical application. The confidence interval approach is used to rank the degrees of the influence of the independent variables in linear models and achieve the goal. An illustrative example is given, and the modeling procedure is studied to check the assumptions step by step in this example to make sure the assumptions satisfied in the true model. As a result, the proposed method can be used efficiently.