信香符、琼书与家书:元明时期道教清微派的通师文书

元明时期的清微派不仅构建了完整的宗师谱系,而且在道法科仪中法师还通过焚信香符,呈送琼书、家书、笺状等通师文书与居于仙境的师真进行交流,请求师真将斋法的意图转达给天帝,从而请天帝颁布敕旨给相关主司神祇以实现法师的诉求。从元明时期清微派师道思想中,我们可以看出其体现了道教"天人合一"的宇宙观,认为人与天地万物都秉承了道炁,所以能够彼此感通,而感通的关键则在于法师修行正心诚意之功。

我们的事业比蜜甜

相信很多上了年纪的观众应该对一部名叫《甜蜜的事业》的老电影很熟悉,其中的主题曲也非常好听,叫《我们的明天比蜜甜》。接下来介绍的这两位,正是从那个年代走来的,用他们的话说,就应该把这主题曲给改一下了,叫《我们的事业比蜜甜》。

Bioinformatic Analysis of BBTV Satellite DNA in Hainan

Banana bunchy top virus (BBTV),family Nanaviridae,genus Babuvirus,is a single stranded DNA virus (ssDNA) that causes banana bunchy top disease (BBTD) in banana plants.It is the most common and most destructive of all viruses in these plants and is widespread throughout the Asia-Pacific region.In this study we isolated,cloned and sequenced a BBTV sample from Hainan Island,China.The results from sequencing and bioinformatics analysis indicate this isolate represents a satellite DNA component with 12 DNA sequences motifs.We also predicted the physical and chemical properties,structure,signal peptide,phosphorylation,secondary structure,tertiary structure and functional domains of its encoding protein,and compare them with the corresponding quantities in the replication initiation protein of BBTV DNA1.

The matrix representation for the mathematic structure of Shannon’s information measures

Shannon’s information measure is a crucial concept in Information Theory. And the research, for the mathematics structure of Shannon’s information measure, is to recognize the essence of information measure. The linear relation between Shannon’s information measures and some signed measure space by using the formal symbols substitution rule is discussed. Furthermore, the coefficient matrix recurrent formula of the linear relation is obtained. Then the coefficient matrix is proved to be invertible via mathematical induction. This shows that the linear relation is one-to-one, and according to this, it can be concluded that a compact space can be generated from Shannon’s information measures.

Double-Space-Cooperation Method for Increasing Channel Capacity

Shannon channel capacity theorem poses highest bit-rate of error free transmission over additive white Gaussian noise channel.In addition,he proved that there exists channel code that can theoretically achieve the channel capacity.Indeed fortunately,the latter researchers found some practical channel codes approaching the channel capacity with insignificant losses of spectral efficiency under ignorable bit error rate(BER).The authors note,in general,that bits of the channel codes are not independent of each other in code space.Further,we note that the modulated symbols are not independent among them,as well,in Euclidean Space.By exploiting a usage of the dependencies jointly to signal design,we can transmit two independent signal streams through an additive white Gaussian channel and separate them in Euclidean space at the receiver.The capacity of this approach is found larger than that of Shannon capacity in the same channel assumptions.The numerical results confirm the theoretical procedures.

Niuhuang(Bovis Calculus)-Shexiang(Moschus)combination induces apoptosis and inhibits proliferation in hepatocellular carcinoma via PI3K/AKT/mTOR pathway

Objective To investigate the effects of Niuhuang(Bovis Calculus,BC)and Shexiang(Moschus)(BC-Moschus)on human hepatocellular carcinoma(HCC)cells SMMC-7721 and a nude mouse model of subcutaneous xenografts,and to explore its anti-HCC mechanism.Methods The BC-Moschus combination was applied to two liver cancer models in vivo and in vitro.SMMC-7721 was divided into the BC-Moschus group and the control group,and different doses(rude drug dosage 0.625,1.25,2.5,and 5 mg/m L)of BC-Moschus extract were used for the intervention.The proliferation ability of HCC cells was detected using the Cell Counting Kit-8(CCK-8)assay,and the migration ability was detected by a wound healing assay.A subcutaneous xenograft model was prepared using nude mice with human HCC.Specific pathogen-free-grade BALB/c nude mice(5-week-old)were randomly divided into the following groups(n=6 per group):control(0.9%physiological saline 0.2 m L/d),BC-Moschus[BC 45.5 mg/(kg·d)+Moschus 13 mg/(kg·d)],and cisplatin(DDP,intraperitoneal injection5 mg/kg per week)groups.All groups were administered for 14 d.The volume and mass of the subcutaneous xenografts in nude mice were observed.The expression levels of phosphatidylinositol-3 kinase/protein kinase B/mammalian target of rapamycin(PI3K/AKT/mTOR)pathway,apoptosis-associated factor p70 S6 Kinase(S6K),Bax,Bcl-2,caspase-3,and caspase-9 in nude mice subcutaneous xenografts were measured by real-time quantitative PCR(RT-qPCR)and Western blot.Terminal Deoxynucleotidy Transferase-Mediated d UTP NickEnd Labeling(TUNEL)was used for quantitative analysis of apoptotic cells.Results The CCK-8 assay demonstrated that the BC-Moschus combination inhibited HCC cell proliferation in a superior manner to the use of BC and Moschus alone,and the inhibition effect was dose-and time-dependent(P<0.01).The wound healing assay showed that the BC-Moschus combination inhibited HCC cell migration(P<0.01).In the subcutaneous xenograft model of nude mice with human HCC,we found that the tumor volume and weight of the BC-Moschus group were lower than those of the control group(P<0.01).The levels of the PI3K/AKT/m TOR signaling pathway and S6K protein in the BC-Moschus and DDP groups were significantly decreased(P<0.01).The expression level of the anti-apoptotic gene Bcl-2 was downregulated(P<0.05),and the expression of the pro-apoptotic gene Baxand apoptosis-related factors caspase-3 and caspase-9 were significantly upregulated(P<0.01).The TUNEL assays further confirmed that the combination of the BC-Moschuas could promote HCC(P<0.01).Conclusion The BC-Moschus combination inhibited the proliferation and migration ability of HCC cells SMMC-7721 and effectively inhibited the growth of subcutaneous xenografts in nude mice.The mechanism may be closely related to the downregulation of the PI3K/AKT/mTOR pathway,regulation of apoptosis-related protein caspase-3,caspase-9,Bcl-2,and Bax expression,and promotion of apoptosis.

Are eavesdroppers multimodal？ Sensory exploitation of floral signals by a non-native cockroach Blatta orientalis

The study of multi-modal communication has only recently been extended to innate and learned interactions between flowers and their animal visitors, and usually only to pollinators. Here we studied the relevance of floral scent and visual display of a night blooming, putatively hawkmoth-pollinated plant Oenothera acaulis （Onagraceae） in the attraction of non-native cockroaches Blatta orientalis （Blattodea： Blattidae）, which function as facultative floral larcenists in coastal habitats of central Chile. We experimentally decoupled visual （corolla） and olfactory （fragrance） stimuli by presenting paper corollas and green mesh bags, with or without a freshly-picked natural flower inside. We then contrasted the behavioral responses of roaches in these treatments with those to the natural combination of traits in actual flowers and their respective control treatments, measuring the roaches＇ frequency of first visits, mean and total residence time spent in each treatment. The roaches primarily used olfactory cues when approaching O. acaulis flowers at two biologically relevant spatial scales. In addition, the presence of conspecific roaches had a strong influence on recruitment to the experimental arena, increasing the statistical differences among treatments. Our results suggest a primacy of floral fragrance over visual stimuli in the foraging responses of B. orientalis. Olfactory cues were necessary and sufficient to attract the roaches, and the visual cues presented in our manipulations only marginally increased their attraction within a 20 cm diameter of the stimulus. The full spectrum of floral visitation behavior was not elicited by the artificial flowers, suggesting the need for additional tactile or contact chemosensory stimuli not provided by paper. Although the nitrogenous scent compounds that we found in O. acaulis flowers are almost exclusively found in hawkmoth-pollinated flowers, the attractiveness of these compounds to a non-native, facultative flower-visiting insect indicates that they do not function as pollinator-specific signals for hawkmoth attraction .