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食管癌前病变与食管腺癌细胞DNA倍体变化分析 被引量:3
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作者 孙剑经 逯海 张斌 《河北北方学院学报(自然科学版)》 2011年第6期59-61,69,共4页
目的探讨慢性炎症-癌前病变-食管腺癌不同阶段的食管黏膜细胞DNA含量及倍体变化,从细胞代谢水平揭示食管癌的发展过程.方法用流式细胞术对15例检查未见器质性病变者的正常组织,27例胃食管反流病患者(GERD)、25例Barrett食管患者和31例... 目的探讨慢性炎症-癌前病变-食管腺癌不同阶段的食管黏膜细胞DNA含量及倍体变化,从细胞代谢水平揭示食管癌的发展过程.方法用流式细胞术对15例检查未见器质性病变者的正常组织,27例胃食管反流病患者(GERD)、25例Barrett食管患者和31例食管腺癌患者的病变组织细胞DNA含量进行了检测,并对四组的DNA倍体类型、DNA指数(DI)、G2/G1、增殖活性(SPF)和细胞增殖活性指数(PI)做了对比分析.结果食管腺癌22例DNA含量全部为非整倍体变化(DNA指数DI>1.1),Barrett食管25例中仅6例为非整倍体DNA含量,胃食管反流病和健康者无1例为非整倍体DNA含量;食管腺癌组G2/G1、SPF、PI较正常组织和胃食管反流病组均有明显升高(P<0.05),Barrett食管组介于胃食管反流病与食管腺癌之间,并且G2/G1、SPF和PI指标差异均有统计学意义(P<0.05).流式细胞术诊断阳性率差异显著.结论食管癌的发展是一个渐进的过程,各阶段之间密切相关. 展开更多
关键词 食管腺癌 癌前病变 DNA含量 倍体变化
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Study on Haploid Induction Rates in Different Maize Inducers 被引量:1
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作者 Guanghui HU 《Agricultural Science & Technology》 CAS 2014年第4期554-556,共3页
[Objective] The aim was to analyze the differences in haploid induction rates of different inducers. [Method] Six maize inducers with purple spot and purple color were selected as the male parents to pollinate six inb... [Objective] The aim was to analyze the differences in haploid induction rates of different inducers. [Method] Six maize inducers with purple spot and purple color were selected as the male parents to pollinate six inbred lines. [Result] The mean haploid induction rates were significantly different among the inducers: KMS-3 >WY-1 >PR-2 >YP-13 >KMS-2 >KMS-1. The haploid induction rates of the different hybrid materials were significantly different: K410 >105A >103A >104A >107A >D271 >106A>L73>N21>KZ58. [Conclusion] The haploid inducer line PR-2, which had high haploid induction rate and low variation coefficient, was an elite haploid inducer. 展开更多
关键词 Maize (Zea mays L.) HAPLOID Haploid inducer Haploid induction rate
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