infants.Methods:Systematic searches in PubMed,EMBASE,The Cochrane Library,Web of Science,Chinese biomedical literature database,China National Knowledge Infrastructure,Wanfang medical and VIP database were performed f...infants.Methods:Systematic searches in PubMed,EMBASE,The Cochrane Library,Web of Science,Chinese biomedical literature database,China National Knowledge Infrastructure,Wanfang medical and VIP database were performed for randomized controlled trials(RCTs)or quasi-RCTs which explored the effects of FICare mode on growth and development of premature infants in neonatal intensive care unit.Then,meta-analysis was performed by RevMan 5.3 after two independent investigators screened the literature,extracted the data and evaluated the risk of bias of all included studies.Results:A total of 14 articles were included,including 3120 preterm infants and their families.Meta-analysis showed that compared with the traditional management mode,FICare mode can effectively improve the growth rate of premature infants'weight[Weight mean difference(WMD)=4.02,95%CI(2.47,5.56),P<0.001],increase sleep time[WMD=3.25,95%CI(2.05,4.44),P<0.001],improve breastfeeding rate[RR=1.38,95%CI(1.15,1.64),P<0.001],reduce readmission rate[Relative risk(RR)=0.49,95%CI(0.33,0.71),P<0.001],promote the development of the nervous system[WMD=3.96,95%CI(3.18,4.74),P<0.001],improve nursing skills of Premature infants'parents[WMD=17.40,95%CI(13.64,21.1),P<0.001],reduce the influence of maternal and infant separation on parents'emotions.Conclusion:FICare mode can effectively promote the growth and development of premature infants and alleviate the harm caused by the separation of mother and infants.Limited by the quality and region of the included studies,the appeal conclusion still needs to be tested by more high-quality studies.展开更多
There is a deficiency of nurseries in the world producing fruit trees using the organic material management. However, such material has been produced since 2009 at the Research Institute of Horticulture in Skierniewic...There is a deficiency of nurseries in the world producing fruit trees using the organic material management. However, such material has been produced since 2009 at the Research Institute of Horticulture in Skierniewice. To stimulate plant growth, various biopreparations were applied in an organic nursery. Apple trees ('Topaz'/M26) obtained from the organic nursery were used to establish an orchard in 2011. One of the combinations in the orchard consisted of trees produced in a conventional nursery. Trees whose maidens had not been fertilized at all in the organic nursery served as the control. The study was conducted for four years (2011-2014). The least vigorously growing trees were the control trees and those that had been treated in the nursery with the preparation Tytanit, and the most vigorously--those that had been treated there with manure and the biopreparations Micosat, Humus Active + Aktywit PM, and BF Quality and BF Amin. Trees whose maidens had been produced by the conventional method did not differ, in terms of growth vigour, from those treated with the biopreparations Humus UP or Vinassa. The highest cumulative fruit yields from the four-year-old trees were obtained in the combinations where the maidens had been treated in the nursery with the biopreparations BF Amin and BF Quality. The type of fertilization applied to maiden trees in the nursery had no significant effect on mean fruit weight, but it influenced the distribution of fruit in size classes.展开更多
Objective:Polycystic ovary syndrome(PCOS),a common endocrine-metabolic dysfunction in reproductive-aged women,may be involved in compromised pregnancy and offspring outcomes.This study aimed to investigate whether mat...Objective:Polycystic ovary syndrome(PCOS),a common endocrine-metabolic dysfunction in reproductive-aged women,may be involved in compromised pregnancy and offspring outcomes.This study aimed to investigate whether maternal PCOS affects fetal growth,fetal development,and placental features.Methods:This retrospective case-control study included 60 pregnant women with PCOS(PCOS group)and 120 healthy pregnant women without PCOS(control group).Fetal magnetic resonance imaging(MRI)was performed followed by an ultrasound examination and indications for imaging,including known or suspected fetal pathology,history of fetal abnormality in previous pregnancy or in a family member,and concern for placenta accreta.Fetal MRI images were analyzed for head cir-cumference(HC),abdomen circumference(AC),lung-to-liver signal intensity ratio(LLSIR,a prenatal marker of fetal lung maturity),lengths of liver and kidney diameters in fetuses,and placental relative signal intensity on T2-weighted single-shot fast spin echo(SSFSE)imaging(rSISSFSE),and placental relative apparent diffusion coefficient value(rADC).Data on height and weight of offspring were collected through telephone follow-up.Results:Compared to the control group,the PCOS group showed the following characteristics:(1)smaller biparietal diameter and femur length in fetuses(P=0.026 and P=0.005,respectively),(2)smaller HC in fetuses(evident after 32 weeks;P=0.044),(3)lower LLSIR and smaller dorsoventral length of liver in fetuses(evident before 32 weeks;P=0.005 and P=0.019,respec-tively),and(4)smaller placental thickness(evident before 32 weeks;P=0.017).No significant differences in placental rSISSFSE or rADC were observed between the groups(all P>0.05).No significant differences in height and weight of offspring during childhood existed between the groups(all P>0.05).Conclusions:There exist alterations of fetal growth,fetal development,and placental features from women with PCOS.展开更多
文摘infants.Methods:Systematic searches in PubMed,EMBASE,The Cochrane Library,Web of Science,Chinese biomedical literature database,China National Knowledge Infrastructure,Wanfang medical and VIP database were performed for randomized controlled trials(RCTs)or quasi-RCTs which explored the effects of FICare mode on growth and development of premature infants in neonatal intensive care unit.Then,meta-analysis was performed by RevMan 5.3 after two independent investigators screened the literature,extracted the data and evaluated the risk of bias of all included studies.Results:A total of 14 articles were included,including 3120 preterm infants and their families.Meta-analysis showed that compared with the traditional management mode,FICare mode can effectively improve the growth rate of premature infants'weight[Weight mean difference(WMD)=4.02,95%CI(2.47,5.56),P<0.001],increase sleep time[WMD=3.25,95%CI(2.05,4.44),P<0.001],improve breastfeeding rate[RR=1.38,95%CI(1.15,1.64),P<0.001],reduce readmission rate[Relative risk(RR)=0.49,95%CI(0.33,0.71),P<0.001],promote the development of the nervous system[WMD=3.96,95%CI(3.18,4.74),P<0.001],improve nursing skills of Premature infants'parents[WMD=17.40,95%CI(13.64,21.1),P<0.001],reduce the influence of maternal and infant separation on parents'emotions.Conclusion:FICare mode can effectively promote the growth and development of premature infants and alleviate the harm caused by the separation of mother and infants.Limited by the quality and region of the included studies,the appeal conclusion still needs to be tested by more high-quality studies.
文摘There is a deficiency of nurseries in the world producing fruit trees using the organic material management. However, such material has been produced since 2009 at the Research Institute of Horticulture in Skierniewice. To stimulate plant growth, various biopreparations were applied in an organic nursery. Apple trees ('Topaz'/M26) obtained from the organic nursery were used to establish an orchard in 2011. One of the combinations in the orchard consisted of trees produced in a conventional nursery. Trees whose maidens had not been fertilized at all in the organic nursery served as the control. The study was conducted for four years (2011-2014). The least vigorously growing trees were the control trees and those that had been treated in the nursery with the preparation Tytanit, and the most vigorously--those that had been treated there with manure and the biopreparations Micosat, Humus Active + Aktywit PM, and BF Quality and BF Amin. Trees whose maidens had been produced by the conventional method did not differ, in terms of growth vigour, from those treated with the biopreparations Humus UP or Vinassa. The highest cumulative fruit yields from the four-year-old trees were obtained in the combinations where the maidens had been treated in the nursery with the biopreparations BF Amin and BF Quality. The type of fertilization applied to maiden trees in the nursery had no significant effect on mean fruit weight, but it influenced the distribution of fruit in size classes.
基金Project supported by the National Natural Science Foundation of China(Nos.81874480 and 81873837)the Zhejiang Province Science Foundation for Distinguished Young Scholars(No.LR16H040001),China。
文摘Objective:Polycystic ovary syndrome(PCOS),a common endocrine-metabolic dysfunction in reproductive-aged women,may be involved in compromised pregnancy and offspring outcomes.This study aimed to investigate whether maternal PCOS affects fetal growth,fetal development,and placental features.Methods:This retrospective case-control study included 60 pregnant women with PCOS(PCOS group)and 120 healthy pregnant women without PCOS(control group).Fetal magnetic resonance imaging(MRI)was performed followed by an ultrasound examination and indications for imaging,including known or suspected fetal pathology,history of fetal abnormality in previous pregnancy or in a family member,and concern for placenta accreta.Fetal MRI images were analyzed for head cir-cumference(HC),abdomen circumference(AC),lung-to-liver signal intensity ratio(LLSIR,a prenatal marker of fetal lung maturity),lengths of liver and kidney diameters in fetuses,and placental relative signal intensity on T2-weighted single-shot fast spin echo(SSFSE)imaging(rSISSFSE),and placental relative apparent diffusion coefficient value(rADC).Data on height and weight of offspring were collected through telephone follow-up.Results:Compared to the control group,the PCOS group showed the following characteristics:(1)smaller biparietal diameter and femur length in fetuses(P=0.026 and P=0.005,respectively),(2)smaller HC in fetuses(evident after 32 weeks;P=0.044),(3)lower LLSIR and smaller dorsoventral length of liver in fetuses(evident before 32 weeks;P=0.005 and P=0.019,respec-tively),and(4)smaller placental thickness(evident before 32 weeks;P=0.017).No significant differences in placental rSISSFSE or rADC were observed between the groups(all P>0.05).No significant differences in height and weight of offspring during childhood existed between the groups(all P>0.05).Conclusions:There exist alterations of fetal growth,fetal development,and placental features from women with PCOS.