Aims:To determine the refractive status and ocular dimensions of a cohort of children at age 10-12 years with birth weight below 1701 g,and also the relation between the neonatal ophthalmic findings and subsequent ref...Aims:To determine the refractive status and ocular dimensions of a cohort of children at age 10-12 years with birth weight below 1701 g,and also the relation between the neonatal ophthalmic findings and subsequent refractive state.Methods:293 low birth weight children who had been examined in the neonatal period were assessed at 10-12 years of age.The examination consisted of autorefraction,keratometry,and A-scan.Results of right eyes were compared with published normative data.Results:293 of the birth cohort of 572 children consented to participate.The average mean spherical equivalent(MSE)in the low birth weight cohort was+ 0.691 dioptre,significantly higher than the control data(+ 0.30D,p=0.02).The average change in MSE over the 10-12 year period was-1.00 dioptre(n=256),but only 62.1% of cases showed a shift in refractive error of the appropriate magnitude and direction.The presence of any retinopathy of prematurity(ROP)increases the risk of developing anisometropia sixfold.Conclusions:Low birth weight and ROP both significantly impact the refractive state in the long term.At age 10-12 years children born preterm have an increased prevalence of all refractive errors.In low birth weight children refractive state is relatively stable over the first decade of life with a shift towards myopia of 1 dioptre.展开更多
在最终将导致2型糖尿病或代谢综合征的各种病理过程中，高胰岛素血症性胰岛素抵抗和内脏型肥胖在早期即可出现。其中一种相当普遍的发病过程即开始于出生前生长受限及幼年时体重自发性追赶增长。进入这种发病过程的儿童在4岁时即使没有...在最终将导致2型糖尿病或代谢综合征的各种病理过程中，高胰岛素血症性胰岛素抵抗和内脏型肥胖在早期即可出现。其中一种相当普遍的发病过程即开始于出生前生长受限及幼年时体重自发性追赶增长。进入这种发病过程的儿童在4岁时即使没有肥胖，也有发生高胰岛素血症和体脂增多的倾向。目前尚不清楚何时开始出现内脏脂肪增多。我们观察了小于孕龄儿（small for gestational age，SGA）经追赶生长后在4—6岁时高胰岛素血症和肥胖是否加重，以及6岁时是否已出现内脏脂肪过多。展开更多
文摘Aims:To determine the refractive status and ocular dimensions of a cohort of children at age 10-12 years with birth weight below 1701 g,and also the relation between the neonatal ophthalmic findings and subsequent refractive state.Methods:293 low birth weight children who had been examined in the neonatal period were assessed at 10-12 years of age.The examination consisted of autorefraction,keratometry,and A-scan.Results of right eyes were compared with published normative data.Results:293 of the birth cohort of 572 children consented to participate.The average mean spherical equivalent(MSE)in the low birth weight cohort was+ 0.691 dioptre,significantly higher than the control data(+ 0.30D,p=0.02).The average change in MSE over the 10-12 year period was-1.00 dioptre(n=256),but only 62.1% of cases showed a shift in refractive error of the appropriate magnitude and direction.The presence of any retinopathy of prematurity(ROP)increases the risk of developing anisometropia sixfold.Conclusions:Low birth weight and ROP both significantly impact the refractive state in the long term.At age 10-12 years children born preterm have an increased prevalence of all refractive errors.In low birth weight children refractive state is relatively stable over the first decade of life with a shift towards myopia of 1 dioptre.
文摘在最终将导致2型糖尿病或代谢综合征的各种病理过程中，高胰岛素血症性胰岛素抵抗和内脏型肥胖在早期即可出现。其中一种相当普遍的发病过程即开始于出生前生长受限及幼年时体重自发性追赶增长。进入这种发病过程的儿童在4岁时即使没有肥胖，也有发生高胰岛素血症和体脂增多的倾向。目前尚不清楚何时开始出现内脏脂肪增多。我们观察了小于孕龄儿（small for gestational age，SGA）经追赶生长后在4—6岁时高胰岛素血症和肥胖是否加重，以及6岁时是否已出现内脏脂肪过多。
