Aim:To study the distribution of anisometropia and anisoa-stigmatismin young Australian children,togetherwith clinical and ocular biometry relations.Method:The Sydney Myopia Study examined 1765 predominantly 6 year ol...Aim:To study the distribution of anisometropia and anisoa-stigmatismin young Australian children,togetherwith clinical and ocular biometry relations.Method:The Sydney Myopia Study examined 1765 predominantly 6 year old children from 34 randomly selected Sydney schools during 2003-4.Keratometry,cycloplegic autorefraction,and questionnaire data were collected.Results:Spherical equivalent(SE)anisometropia(≥ 1 dioptre)prevalence was 1.6%(95% confidence interval(CI)-1.1% to 2.4%).Aniso-astigmatism(≥ 1D)prevalence was 1.0%(CI:0.6% to 1.6%).Both conditions were significantly more prevalent among moderately hyperopic(SE ≥ 2.0D)thanmildly hyperopic(SE 0.5-1.9D)children.Myopic children(SE ≤-0.5D)had higher anisometropia prevalence.Neither condition varied by age,sex,or ethnicity.In multivariate analyses,anisometropia was significantly associated with amblyopia,odds ratio(OR)29,(CI:8.7 to 99),exotropia(OR 7.7,CI:1.2 to 50),and neonatal intensive care unit(NICU)admission(OR 3.6,CI:1.1 to 12.6).Aniso-astigmatism was significantly associated with amblyopia(OR 8.2,CI:1.4 to 47),maternal age > 35 years(OR 4.0,CI:1.3 to 11.9),and NICU admission(OR 4.6,CI:1.2 to 17.2).Anisometropia resulted from relatively large interocular differences in axial length(p < 0.0001)and anterior chamber depth(p=0.0009).Aniso-astigmatism resulted from differences in corneal astigmatism(p < 0.0001).Conclusion:In this predominantly 6 year old population,anisometropia and aniso-astigmatism were uncommon,had important birth and biometry associations,and were strongly related to amblyopia and strabismus.展开更多
文摘Aim:To study the distribution of anisometropia and anisoa-stigmatismin young Australian children,togetherwith clinical and ocular biometry relations.Method:The Sydney Myopia Study examined 1765 predominantly 6 year old children from 34 randomly selected Sydney schools during 2003-4.Keratometry,cycloplegic autorefraction,and questionnaire data were collected.Results:Spherical equivalent(SE)anisometropia(≥ 1 dioptre)prevalence was 1.6%(95% confidence interval(CI)-1.1% to 2.4%).Aniso-astigmatism(≥ 1D)prevalence was 1.0%(CI:0.6% to 1.6%).Both conditions were significantly more prevalent among moderately hyperopic(SE ≥ 2.0D)thanmildly hyperopic(SE 0.5-1.9D)children.Myopic children(SE ≤-0.5D)had higher anisometropia prevalence.Neither condition varied by age,sex,or ethnicity.In multivariate analyses,anisometropia was significantly associated with amblyopia,odds ratio(OR)29,(CI:8.7 to 99),exotropia(OR 7.7,CI:1.2 to 50),and neonatal intensive care unit(NICU)admission(OR 3.6,CI:1.1 to 12.6).Aniso-astigmatism was significantly associated with amblyopia(OR 8.2,CI:1.4 to 47),maternal age > 35 years(OR 4.0,CI:1.3 to 11.9),and NICU admission(OR 4.6,CI:1.2 to 17.2).Anisometropia resulted from relatively large interocular differences in axial length(p < 0.0001)and anterior chamber depth(p=0.0009).Aniso-astigmatism resulted from differences in corneal astigmatism(p < 0.0001).Conclusion:In this predominantly 6 year old population,anisometropia and aniso-astigmatism were uncommon,had important birth and biometry associations,and were strongly related to amblyopia and strabismus.
