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利用光压差分技术筛选细胞的影响参数 被引量:2
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作者 程景萌 杨丽 +2 位作者 周围 李新冉 张思祥 《光学精密工程》 EI CAS CSCD 北大核心 2017年第8期2029-2037,共9页
本文采用有限体积法建立了交叉型细胞分离模型,提出了一种基于光压差分的细胞筛选仿真方法,分析微流体中细胞筛选的影响因素。基于层流、流体流动粒子追踪、波动光学理论,利用有限元分析法建立了一种交叉型光学颗粒分离模型,研究了利用... 本文采用有限体积法建立了交叉型细胞分离模型,提出了一种基于光压差分的细胞筛选仿真方法,分析微流体中细胞筛选的影响因素。基于层流、流体流动粒子追踪、波动光学理论,利用有限元分析法建立了一种交叉型光学颗粒分离模型,研究了利用光压差分技术分离细胞的各种影响因素,其中包括微粒直径,激光功率、温度、光纤直径,分析了微粒在流体中因光辐射压力作用下的偏移距离。实验结果表明:在微流体中,激光功率、细胞直径、温度(20℃)和偏移距离大体上成正比关系,光纤直径和细胞直径在大小相当的情况下光辐射压力能够达到最大值,当激光通过光纤作用于直径分别为3,8和20μm的微粒时,光纤直径为7μm或8μm时光辐射压力最大,所以选用直径为8μm的单模光纤作为一个重要的实验光学器件。所得结论为深入研究细胞筛选影响因素的数值仿真精度提供了参考与借鉴。 展开更多
关键词 细胞分离 光纤 光辐射压力 光压差分 数值仿真
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Research Progress of Optical H2O Sensor With a DFB Diode Laser 被引量:2
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作者 Guangping LV Jun CHANG Qingpu WANG Qiang WANG Wei WEI 《Photonic Sensors》 SCIE EI CAS 2014年第2期113-119,共7页
In the field of near infrared H2O sensing, the acquisition of the absorption signal usually is from a noisy background, thus it is important to adopt an effective signal demodulation method. This study introduced the ... In the field of near infrared H2O sensing, the acquisition of the absorption signal usually is from a noisy background, thus it is important to adopt an effective signal demodulation method. This study introduced the research progress in the field of trace water vapor detection, covering different individual gas detection techniques. On the basis of the conventional double-beam differential absorption, the division method in voltage and the dual-peak method based on the differential value of two adjacent absorption lines have been studied. Voltage division has an excellent stability to temperature variation, mechanical extrusion, and fiber bend loss. The dual-peak method proved a linear relation with the water vapor concentration, and this method provided a way to measure the concentration at high pressure. Furthermore, the so called balanced ratiometer detection (BRD) was introduced. It has an outstanding self-adjusting capability, and it can also avoid an excess phase difference caused by the current-to-voltage converting circuit, thus this method has a high sensitivity. In addition, the second harmonic technique applied to gas detection was introduced, and for the high-frequency modulation via driving current, l/f was suppressed apparently; as a result, this technique realized a better sensitive detection by one to two orders of magnitude. 展开更多
关键词 Water vapor gas sensing DFB diode laser absorption spectrum
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