目的:评估光学增强内镜(Optical Enhancement,OE)或OE联合放大内镜(放大OE)在胃肠上皮化生诊断中的临床应用价值。方法:选取2017年1月~2021年5月在山东大学齐鲁医院行放大内镜检查的患者135例,检查顺序为白光内镜-OE内镜-放大OE,分别根...目的:评估光学增强内镜(Optical Enhancement,OE)或OE联合放大内镜(放大OE)在胃肠上皮化生诊断中的临床应用价值。方法:选取2017年1月~2021年5月在山东大学齐鲁医院行放大内镜检查的患者135例,检查顺序为白光内镜-OE内镜-放大OE,分别根据病变的小凹结构及腺管开口和微血管清晰程度和可辨认程度进行量化评分。比较白光内镜与OE、放大OE图像清晰度。放大OE下分别记录每处病变亮蓝嵴(Light Blue Crest,LBC)、绒毛状结构(Villous Pattern,VP)、大长冠(Large Long Crest,LLC)情况,与病理学比较对GIM的诊断价值。结果:OE和放大OE评价图像清晰度优于白光内镜,差异具有统计学意义(P=0.001,P<0.001)。LBC、VP、LLC对诊断GIM的准确度分别为82.46%、76.02%、81.29%,并具有统计学意义(P<0.001)。同时满足三个特征诊断GIM准确度为94.74%。结论:在观察病变的清晰度方面,OE放大内镜显著优于OE和白光内镜,OE内镜优于白光内镜。LBC、VP、LLC是放大OE下胃肠上皮化生的特征性表现,内镜下符合三种特征的病变能准确诊断肠上皮化生,LBC诊断肠上皮化生的准确度优于VP和LLC。展开更多
Recent technological advances in miniaturization have allowed for a confocal scanning microscope to be integrated into a conventional flexible endoscope,or into trans-endoscopic probes,a technique now known as confoca...Recent technological advances in miniaturization have allowed for a confocal scanning microscope to be integrated into a conventional flexible endoscope,or into trans-endoscopic probes,a technique now known as confocal endomicroscopy or confocal laser endomicroscopy.This newly-developed technology has enabled endoscopists to collect real-time in vivo histological images or "virtual biopsies" of the gastrointestinal mucosa during endoscopy,and has stimulated significant interest in the application of this technique in clinical gastroenterology.This review aims to evaluate the current data on the technical aspects and the utility of this new technology in clinical gastroenterology and its potential impact in the future,particularly in the screening or surveillance of gastrointestinal neoplasia.展开更多
senile population Objective To compare ocular biometric values in angle closure glaucoma and cataract in Methods Ocular biometry was performed in eyes classified to have angle closure glaucoma （29 eyes） and senile c...senile population Objective To compare ocular biometric values in angle closure glaucoma and cataract in Methods Ocular biometry was performed in eyes classified to have angle closure glaucoma （29 eyes） and senile cataract （31 eyes）. Ocular biometry readings between two groups were compared and analyzed statistically, lntraocular pressure was also recorded before and after lens extraction. Results Anterior chamber depth was shallower in patients with angle closure glaucoma group [ （ 1, 79 ± 0. 56 ） mm ] compared with senile cataract group [ （2.69 ±0. 40） mm ] （ P 〈 0.01 ）. Lens thickness was greater in angle closure glaucoma group [ （5.30 ±0. 61） mm ] than that in senile cataract group [ （3.84 ＋-0. 61） mm ] （ P 〈0. 01）. Phacoemusification was performed in 5 patients with persistent acute attack of angle closure glaucoma, lOPs were controlled in all five cases after lens extraction. Conclusion Eyes with angle closure glaucoma seems to have significantly shallow anterior chamber and greater lens thickness compared to senile cataract eyes in the same age. Lens extraction might be effective in those cases with such anatomy features.展开更多
文摘目的:评估光学增强内镜(Optical Enhancement,OE)或OE联合放大内镜(放大OE)在胃肠上皮化生诊断中的临床应用价值。方法:选取2017年1月~2021年5月在山东大学齐鲁医院行放大内镜检查的患者135例,检查顺序为白光内镜-OE内镜-放大OE,分别根据病变的小凹结构及腺管开口和微血管清晰程度和可辨认程度进行量化评分。比较白光内镜与OE、放大OE图像清晰度。放大OE下分别记录每处病变亮蓝嵴(Light Blue Crest,LBC)、绒毛状结构(Villous Pattern,VP)、大长冠(Large Long Crest,LLC)情况,与病理学比较对GIM的诊断价值。结果:OE和放大OE评价图像清晰度优于白光内镜,差异具有统计学意义(P=0.001,P<0.001)。LBC、VP、LLC对诊断GIM的准确度分别为82.46%、76.02%、81.29%,并具有统计学意义(P<0.001)。同时满足三个特征诊断GIM准确度为94.74%。结论:在观察病变的清晰度方面,OE放大内镜显著优于OE和白光内镜,OE内镜优于白光内镜。LBC、VP、LLC是放大OE下胃肠上皮化生的特征性表现,内镜下符合三种特征的病变能准确诊断肠上皮化生,LBC诊断肠上皮化生的准确度优于VP和LLC。
文摘Recent technological advances in miniaturization have allowed for a confocal scanning microscope to be integrated into a conventional flexible endoscope,or into trans-endoscopic probes,a technique now known as confocal endomicroscopy or confocal laser endomicroscopy.This newly-developed technology has enabled endoscopists to collect real-time in vivo histological images or "virtual biopsies" of the gastrointestinal mucosa during endoscopy,and has stimulated significant interest in the application of this technique in clinical gastroenterology.This review aims to evaluate the current data on the technical aspects and the utility of this new technology in clinical gastroenterology and its potential impact in the future,particularly in the screening or surveillance of gastrointestinal neoplasia.
文摘senile population Objective To compare ocular biometric values in angle closure glaucoma and cataract in Methods Ocular biometry was performed in eyes classified to have angle closure glaucoma （29 eyes） and senile cataract （31 eyes）. Ocular biometry readings between two groups were compared and analyzed statistically, lntraocular pressure was also recorded before and after lens extraction. Results Anterior chamber depth was shallower in patients with angle closure glaucoma group [ （ 1, 79 ± 0. 56 ） mm ] compared with senile cataract group [ （2.69 ±0. 40） mm ] （ P 〈 0.01 ）. Lens thickness was greater in angle closure glaucoma group [ （5.30 ±0. 61） mm ] than that in senile cataract group [ （3.84 ＋-0. 61） mm ] （ P 〈0. 01）. Phacoemusification was performed in 5 patients with persistent acute attack of angle closure glaucoma, lOPs were controlled in all five cases after lens extraction. Conclusion Eyes with angle closure glaucoma seems to have significantly shallow anterior chamber and greater lens thickness compared to senile cataract eyes in the same age. Lens extraction might be effective in those cases with such anatomy features.
