While the activation of primary somatosensory(SI) cortex during pain perception is consistently reported in functional imaging studies on normal subjects and chronic pain patients,the specific roles of SI,particularly...While the activation of primary somatosensory(SI) cortex during pain perception is consistently reported in functional imaging studies on normal subjects and chronic pain patients,the specific roles of SI,particularly the subregions within SI,in the processing of sensory aspects of pain are still largely unknown.Using optical imaging of intrinsic signal(OIS) and single unit electrophysiology,we studied cortical activation patterns within SI cortex(among Brodmann areas 3a,3b and 1) and signal amplitude changes to various intensities of non-nociceptive,thermal nociceptive and mechanical nociceptive stimulation of individual distal finerpads in anesthetized squirrel monkeys.We have demonstrated that areas 3a and 1 are preferentially involved in the processing of nociceptive information while areas 3b and 1 are preferentially activated in the processing of non-nociceptive(touch) information.Nociceptive activations of individual fingerpad were organized topographically suggesting that nociceptive topographic map exits in areas 3a and 1.Signal amplitude was enhanced to increasing intensity of mechanical nociceptive stimuli in areas 3a,3b and 1.Within area 1,nociceptive response co-localizes with the non-nociceptive response.Therefore,we hypothesize that nocicepitve information is area-specifically represented within SI cortex,in which nociceptive inputs are preferentially represented in areas 3a and 1 while non-nociceptive inputs are preferentially represented in areas 3b and 1.展开更多
The objective assessment of fabric pilling based on light projection and image analysis has been exploited recently.The device for capturing the cross-sectional images of the pilled fabrics with light projection is el...The objective assessment of fabric pilling based on light projection and image analysis has been exploited recently.The device for capturing the cross-sectional images of the pilled fabrics with light projection is elaborated.The detection of the profile line and integration of the sequential cross-sectional pilled image are discussed.The threshold based on Gaussian model is recommended for pill segmentation.The results show that the installed system is capable of eliminating the interference with pill information from the fabric color and pattern.展开更多
文摘While the activation of primary somatosensory(SI) cortex during pain perception is consistently reported in functional imaging studies on normal subjects and chronic pain patients,the specific roles of SI,particularly the subregions within SI,in the processing of sensory aspects of pain are still largely unknown.Using optical imaging of intrinsic signal(OIS) and single unit electrophysiology,we studied cortical activation patterns within SI cortex(among Brodmann areas 3a,3b and 1) and signal amplitude changes to various intensities of non-nociceptive,thermal nociceptive and mechanical nociceptive stimulation of individual distal finerpads in anesthetized squirrel monkeys.We have demonstrated that areas 3a and 1 are preferentially involved in the processing of nociceptive information while areas 3b and 1 are preferentially activated in the processing of non-nociceptive(touch) information.Nociceptive activations of individual fingerpad were organized topographically suggesting that nociceptive topographic map exits in areas 3a and 1.Signal amplitude was enhanced to increasing intensity of mechanical nociceptive stimuli in areas 3a,3b and 1.Within area 1,nociceptive response co-localizes with the non-nociceptive response.Therefore,we hypothesize that nocicepitve information is area-specifically represented within SI cortex,in which nociceptive inputs are preferentially represented in areas 3a and 1 while non-nociceptive inputs are preferentially represented in areas 3b and 1.
基金This research was supported by the Research Fund for Etoctoral Program of Higher Education (No. 99025508)
文摘The objective assessment of fabric pilling based on light projection and image analysis has been exploited recently.The device for capturing the cross-sectional images of the pilled fabrics with light projection is elaborated.The detection of the profile line and integration of the sequential cross-sectional pilled image are discussed.The threshold based on Gaussian model is recommended for pill segmentation.The results show that the installed system is capable of eliminating the interference with pill information from the fabric color and pattern.
