基于DFT的第一性原理计算含间隙锌Zni点缺陷的Zn O体系的晶体结构、电子结构及光学性质随压强变化的规律.结果表明,晶格常数随压强增加而线性减小,原因是压力的增加导致晶胞体积减小.对电子结构和光学性质的研究发现,体系的最小带隙宽...基于DFT的第一性原理计算含间隙锌Zni点缺陷的Zn O体系的晶体结构、电子结构及光学性质随压强变化的规律.结果表明,晶格常数随压强增加而线性减小,原因是压力的增加导致晶胞体积减小.对电子结构和光学性质的研究发现,体系的最小带隙宽度随压强的增加而线性增加,光谱的峰位随压强的变化出现不同的能移,在3.0~4.7 e V光子能量范围内,压强变化对介电峰和吸收峰强度的影响显著.展开更多
Long arm trisomy of chromosome 22 or cat eye syndrome （OMIM#115470） is a disease with an enormous variability of clinical features, ranging from minor malformations like hypertelorism, to major ones, as congenital h...Long arm trisomy of chromosome 22 or cat eye syndrome （OMIM#115470） is a disease with an enormous variability of clinical features, ranging from minor malformations like hypertelorism, to major ones, as congenital heart and renal disorders, combined with variable growth retardation. The authors report a case of a newborn female with clinical features of cat eye syndrome with trisomy 22 in inbred line, who died 35 days after birth. The clinical features at the time of diagnosis were： left preauricular appendix, low-set ears, hypertelorism, mongoloid palpebral apertures, right-sided microphthalmia, left-sided anophthalmia, cleft lip and palate, short neck, anomalous pulmonary venous return, severe lung hypertension, hyperechogenic little kidneys and clinodactyly of the fifth finger on the left side. Cerebral ultrasound showed dilatation of both lateral ventricles, with a callosum corpus difficult to evaluate. The cytogenetics diagnostic was made from peripheral blood by conventional cytogenetics techniques in two different laboratories, and confirmed by fluorescent in situ hybridization.展开更多
Nanotherapeutics has an increasing role in the treatment of diseases such as cancer. In photodynamic therapy （PDT） a therapeutically inactive photosensitizer compound is selectively activated by light to produce mol...Nanotherapeutics has an increasing role in the treatment of diseases such as cancer. In photodynamic therapy （PDT） a therapeutically inactive photosensitizer compound is selectively activated by light to produce molecules capable of killing diseased cells and pathogens. A phototheranostic agent can be defined as a single nanoentity with the capabilities for targeted delivery, optical imaging and photodynamic treatment of a disease. Malignant cells, tissue and microbial etiologic agents can be effectively targeted by PDT. Photodynamic therapy is noninvasive, or minimally invasive, and has few side effects as damage to healthy tissue is minimized and the killing effect is localized. Various forms of cancer, acne and other diseases may be treated. The in vivo efficacy of photosensitizers is further improved by attaching them to nanostructures capable of targeting the diseased site. Such photosensitizer-functionalized nanostructures, or nano- therapeutics, allow site-specific delivery of imaging and therapeutic agents for improved phototheranostic performance. This review explores the potential applications of phototheranostic nanostructures in diagnosis and therapy.展开更多
文摘基于DFT的第一性原理计算含间隙锌Zni点缺陷的Zn O体系的晶体结构、电子结构及光学性质随压强变化的规律.结果表明,晶格常数随压强增加而线性减小,原因是压力的增加导致晶胞体积减小.对电子结构和光学性质的研究发现,体系的最小带隙宽度随压强的增加而线性增加,光谱的峰位随压强的变化出现不同的能移,在3.0~4.7 e V光子能量范围内,压强变化对介电峰和吸收峰强度的影响显著.
文摘Long arm trisomy of chromosome 22 or cat eye syndrome （OMIM#115470） is a disease with an enormous variability of clinical features, ranging from minor malformations like hypertelorism, to major ones, as congenital heart and renal disorders, combined with variable growth retardation. The authors report a case of a newborn female with clinical features of cat eye syndrome with trisomy 22 in inbred line, who died 35 days after birth. The clinical features at the time of diagnosis were： left preauricular appendix, low-set ears, hypertelorism, mongoloid palpebral apertures, right-sided microphthalmia, left-sided anophthalmia, cleft lip and palate, short neck, anomalous pulmonary venous return, severe lung hypertension, hyperechogenic little kidneys and clinodactyly of the fifth finger on the left side. Cerebral ultrasound showed dilatation of both lateral ventricles, with a callosum corpus difficult to evaluate. The cytogenetics diagnostic was made from peripheral blood by conventional cytogenetics techniques in two different laboratories, and confirmed by fluorescent in situ hybridization.
文摘Nanotherapeutics has an increasing role in the treatment of diseases such as cancer. In photodynamic therapy （PDT） a therapeutically inactive photosensitizer compound is selectively activated by light to produce molecules capable of killing diseased cells and pathogens. A phototheranostic agent can be defined as a single nanoentity with the capabilities for targeted delivery, optical imaging and photodynamic treatment of a disease. Malignant cells, tissue and microbial etiologic agents can be effectively targeted by PDT. Photodynamic therapy is noninvasive, or minimally invasive, and has few side effects as damage to healthy tissue is minimized and the killing effect is localized. Various forms of cancer, acne and other diseases may be treated. The in vivo efficacy of photosensitizers is further improved by attaching them to nanostructures capable of targeting the diseased site. Such photosensitizer-functionalized nanostructures, or nano- therapeutics, allow site-specific delivery of imaging and therapeutic agents for improved phototheranostic performance. This review explores the potential applications of phototheranostic nanostructures in diagnosis and therapy.
