A new dual-state emission(DSE) dye comprised of tetraphenylethene(TPE), triphenylamine(TPA), and indoline groups has been synthesized, which showed efficient fluorescence in both solution and solid. The dye is compris...A new dual-state emission(DSE) dye comprised of tetraphenylethene(TPE), triphenylamine(TPA), and indoline groups has been synthesized, which showed efficient fluorescence in both solution and solid. The dye is comprised of three parts and these parts show different fluorescence properties which can be very useful in some applications since the dye can produce information-rich responses. For example, the dye is p H-sensitive in both solution and solid states, and it emits yellow fluorescence in normal p H and red/NIR fluorescence in acidic condition. Cytotoxicity of the dye is low at concentration of 3 μM which was confirmed by a methyl thiazolyl tetrazolium(MTT) experiment, and in vitro experiments revealed that the p H responsive performance can be used in bioimaging. It provides a novel p H-sensitive DSE dye ever reported, which has potential application in many fields.展开更多
The extinction phenomenon induced by multiplicative non-Gaussian L′evy noise in a tumor growth model with immune response is discussed. Under the influence of the stochastic immune rate, the model is analyzed in term...The extinction phenomenon induced by multiplicative non-Gaussian L′evy noise in a tumor growth model with immune response is discussed. Under the influence of the stochastic immune rate, the model is analyzed in terms of a stochastic differential equation with multiplicative noise. By means of the theory of the infinitesimal generator of Hunt processes, the escape probability, which is used to measure the noise-induced extinction probability of tumor cells, is explicitly expressed as a function of initial tumor cell density, stability index and noise intensity. Based on the numerical calculations, it is found that for different initial densities of tumor cells, noise parameters play opposite roles on the escape probability. The optimally selected values of the multiplicative noise intensity and the stability index are found to maximize the escape probability.展开更多
基金supported by the National Natural Science Foundation of China (51673180, 51373162)
文摘A new dual-state emission(DSE) dye comprised of tetraphenylethene(TPE), triphenylamine(TPA), and indoline groups has been synthesized, which showed efficient fluorescence in both solution and solid. The dye is comprised of three parts and these parts show different fluorescence properties which can be very useful in some applications since the dye can produce information-rich responses. For example, the dye is p H-sensitive in both solution and solid states, and it emits yellow fluorescence in normal p H and red/NIR fluorescence in acidic condition. Cytotoxicity of the dye is low at concentration of 3 μM which was confirmed by a methyl thiazolyl tetrazolium(MTT) experiment, and in vitro experiments revealed that the p H responsive performance can be used in bioimaging. It provides a novel p H-sensitive DSE dye ever reported, which has potential application in many fields.
基金Supported by the National Natural Science Foundation of China under Grant Nos.10932009,11172233,and 11302169
文摘The extinction phenomenon induced by multiplicative non-Gaussian L′evy noise in a tumor growth model with immune response is discussed. Under the influence of the stochastic immune rate, the model is analyzed in terms of a stochastic differential equation with multiplicative noise. By means of the theory of the infinitesimal generator of Hunt processes, the escape probability, which is used to measure the noise-induced extinction probability of tumor cells, is explicitly expressed as a function of initial tumor cell density, stability index and noise intensity. Based on the numerical calculations, it is found that for different initial densities of tumor cells, noise parameters play opposite roles on the escape probability. The optimally selected values of the multiplicative noise intensity and the stability index are found to maximize the escape probability.
