This paper presents an efficient hierarchical occlusion test algorithm to support the global illumination solution such as Ray Tracing and Radiosity. This method, which is based on a cone volume intersection examinati...This paper presents an efficient hierarchical occlusion test algorithm to support the global illumination solution such as Ray Tracing and Radiosity. This method, which is based on a cone volume intersection examination, can rapidly remove the irrelevant parts in a scene and find the vertices which fall into the shadow area of a given object. It is an effective alternative to the conventional shadow feeler method.展开更多
AIM： To detect the new serum biomarkers for colorectal cancer （CRC） by serum protein profiling with surfaceenhanced laser desorption ionisation - time of flight mass spectrometry （SELDI-TOF MS）. METHODS： Two ind...AIM： To detect the new serum biomarkers for colorectal cancer （CRC） by serum protein profiling with surfaceenhanced laser desorption ionisation - time of flight mass spectrometry （SELDI-TOF MS）. METHODS： Two independent serum sample sets were analysed separately with the ProteinChip technology （set A： 40 CRC ＋ 49 healthy controls; set B： 37 CRC ＋ 31 healthy controls）, using chips with a weak cation exchange moiety and buffer pH 5. Discriminative power of differentially expressed proteins was assessed with a classification tree algorithm. Sensitivities and specificities of the generated classification trees were obtained by blindly applying data from set A to the generated trees from set B and vice versa. CRC serum protein profiles were also compared with those from breast, ovarian, prostate, and non-small cell lung cancer. RESULTS： Mass-to-charge ratios （m/z） 3.1×10^3, 3.3× 10^3, 4.5×10^3, 6.6×10^3 and 28×10^3 were used as classitiers in the best-performing classification trees. Tree sensitivities and specificities were between 65% and 90%.Host of these discriminative m/z values were also different in the other tumour types investigated. M/z 3.3× 10^3, main classifier in most trees, was a doubly charged form of the 6.6× 10^3-Da protein. The latter was identified as apolipoprotein C-I. M/z 3.1×10^3 was identified as an N-terminal fragment of albumin, and m/z 28× 10^3 as apolipoprotein A-I. CONCLUSION： SELDI-TOF MS followed by classification tree pattern analysis is a suitable technique for finding new serum markers for CRC. Biomarkers can be identified and reproducibly detected in independent sample sets with high sensitivities and specificities. Although not specific for CRC, these biomarkers have a potential role in disease and treatment monitoring.展开更多
Previous works have shown that the suction probe cannot be used to accurately measure the upward and downward particle fluxes independently. A new method using a single optical probe to measure the local solid flux is...Previous works have shown that the suction probe cannot be used to accurately measure the upward and downward particle fluxes independently. A new method using a single optical probe to measure the local solid flux is presented. The measurement of upward, downward and net solid fluxes was carried out in a cold model circulating fluidized bed (CFB) unit. The result shows that the profile of the net solid flux is in good agreement with the previous experimental data measured with a suction probe. The comparison between the average solid flux determined with the optical measuring system and the external solid flux was made, and the maximum deviationturned out to be 22%, with the average error being about 6.9%. These confirm that the optical fiber system can be successfully used to measure the upward, downward and net solid fluxes simultaneously by correctly processing the sampling signals obtained from the optical measuring system.展开更多
The bending modulus property of high performance fiber is an important property for both polymer science and engineering. The measurement of the bending performance is, however, difficult because of the thin size of t...The bending modulus property of high performance fiber is an important property for both polymer science and engineering. The measurement of the bending performance is, however, difficult because of the thin size of the fiber. We have measured this property by the axial compression bending method where single fiber with suitable slenderness is compressed in the fiber axial direction to obtain the peak point of the force-displacement curve. Then the bending modulus and the flexural rigidity can be calculated by measuring the protruding length and diameter of fiber needles and the critical force, Pcr. The measured data show that the bending characteristics of all kinds of high performance fiber are dissimilar evidently.展开更多
Today, micro-system technology and the development of new MEMS (Micro-Electro-Mechanical Systems) are emerging rapidly. In order for this development to become a success in the long run, measurement systems have to en...Today, micro-system technology and the development of new MEMS (Micro-Electro-Mechanical Systems) are emerging rapidly. In order for this development to become a success in the long run, measurement systems have to ensure product quality. Most often, MEMS have to be tested by means of functionality or destructive tests. One reason for this is that there are no suitable systems or sensing probes available which can be used for the measurement of quasi inaccessible features like small holes or cavities. We present a measurement system that could be used for these kinds of measurements. The system combines a fiber optical, miniaturized sensing probe with low-coherence interferometry, so that absolute distance measurements with nanometer accuracy are possible.展开更多
Recent advancements in the endoscopic imaging of Barrett's esophagus can be used to probe a wide range of optical properties that are altered with neoplastic progression.This review summarizes relevant changes in ...Recent advancements in the endoscopic imaging of Barrett's esophagus can be used to probe a wide range of optical properties that are altered with neoplastic progression.This review summarizes relevant changes in optical properties as well as imaging approaches that measures those changes.Wide-field imaging approaches include narrow-band imaging that measures changes in light scattering and absorption,and autofluorescence imaging that measure changes in endogenous fluorophores.High-resolution imaging approaches include optical coherence tomography,endocytoscopy,confocal microendoscopy,and high-resolution microendoscopy.These technologies,some coupled with an appropriate contrast agent,can measure differences in glandular morphology,nuclear morphology,or vascular alterations associated with neoplasia.Advances in targeted contrast agents are further discussed.Studies that have explored these technologies are highlighted;as are the advantages and limitations of each.展开更多
Two novel ligands named 4-styrylpyridine-2,6-dicarboxylic acid (4-SPDA) and 4-(4-(2-(2, 6-dicarboxypyridin-4-yl)- vinyl)styryl)pyridine-2,6-dicarboxylic acid(DSPDA) and their complexes with Tb(Ⅲ) were synthesized and...Two novel ligands named 4-styrylpyridine-2,6-dicarboxylic acid (4-SPDA) and 4-(4-(2-(2, 6-dicarboxypyridin-4-yl)- vinyl)styryl)pyridine-2,6-dicarboxylic acid(DSPDA) and their complexes with Tb(Ⅲ) were synthesized and characterized by infrared spectrometry, 1H nuclear magnetic resonance, elemental analysis and gas chromatograph-mass spectrometry. The ligand synthetic route was optimized. The fluorescence properties of the complex in solid state, in different kind of solvents and in solutions with different pH values were investigated in detail. The results show that the yields of DSPDA and 4-SPDA reach over 78% by Wittig-Horner reaction and other eight pyridine-2, 6-dicarboxylic acid derivatives with different substituents on pyridine ring, and their complexes with Tb(Ⅲ) are also obtained. The fluorescence intensities of the complexes with electron-donating groups are more intense than those of the complexes with electron-withdrawing groups on pyridine ring; fluorescence intensities of the complexes are the strongest in neutral solution (pH=7), and the less the dipole moment of solvent molecule is, the stronger the fluorescence intensity is. It is found that the two ligands (4-APDA and DSPDA) are the good sensitizers for Tb(Ⅲ) ion.展开更多
In order to obtain a compact and exact representation of 2D range scans,UKF(unscented Kalman filter) and CDKF(central difference Kalman filter) were proposed for extracting the breakpoint of the laser data. Line extra...In order to obtain a compact and exact representation of 2D range scans,UKF(unscented Kalman filter) and CDKF(central difference Kalman filter) were proposed for extracting the breakpoint of the laser data. Line extraction was performed in every continuous breakpoint region by detecting the optimal angle and the optimal distance in polar coordinates,and every breakpoint area was constructed with two points. As a proof to the method,an experiment was performed by a mobile robot equipped with one SICK laser rangefinder,and the results of UKF/CDKF in breakpoint detection and line extraction were compared with those of the EKF(extended Kalman filter) . The results show that the exact geometry of the raw laser data of the environments can be obtained by segmented raw measurements(combining the proposed breakpoint detection approach with the line extraction method) ,and method UKF is the best one compared with CDKF and EKF.展开更多
The rotatory optics element in the tensor dielectric coefficient matrix is an important para-(meter) for analyzing and calculating a rotatory optical fiber by electromagnetic theory. But the mea-(surement) of rotatory...The rotatory optics element in the tensor dielectric coefficient matrix is an important para-(meter) for analyzing and calculating a rotatory optical fiber by electromagnetic theory. But the mea-(surement) of rotatory optics element is difficult for the rotatory optical fiber. A simple principle and method for measuring rotatory optics element are put forward in this paper. Firstly by using electromagnetic theory it was demonstrated that the rotatory optics element has a simple linear relation with the rotatory angle, and then the rotatory optics element has a simple linear relation with the magnetic field strength (or bias current in the helix coil) . Secondly a measurement system for the rotatory optics element in the rotatory optical fiber was designed. Using the measurement system the rotatory element can be obtained by measuring the bias current simply.展开更多
As one of the interesting optical techniques for measurements of the velocity,the spatial filtering method is treated briefly in this paper.We shown theoretical analysis and calculation of spatial filtering velocimetr...As one of the interesting optical techniques for measurements of the velocity,the spatial filtering method is treated briefly in this paper.We shown theoretical analysis and calculation of spatial filtering velocimetry,and discussed two-dimensional measurements of the velocity.About the data processing,we used A/D conversion and interfaced with a microcomputer,so that the data can be processed automatically by the microcomputer.The preliminary experiment was performed and the experimental results show the usefulness of the present method for measurements of the velocity.展开更多
文摘This paper presents an efficient hierarchical occlusion test algorithm to support the global illumination solution such as Ray Tracing and Radiosity. This method, which is based on a cone volume intersection examination, can rapidly remove the irrelevant parts in a scene and find the vertices which fall into the shadow area of a given object. It is an effective alternative to the conventional shadow feeler method.
文摘AIM： To detect the new serum biomarkers for colorectal cancer （CRC） by serum protein profiling with surfaceenhanced laser desorption ionisation - time of flight mass spectrometry （SELDI-TOF MS）. METHODS： Two independent serum sample sets were analysed separately with the ProteinChip technology （set A： 40 CRC ＋ 49 healthy controls; set B： 37 CRC ＋ 31 healthy controls）, using chips with a weak cation exchange moiety and buffer pH 5. Discriminative power of differentially expressed proteins was assessed with a classification tree algorithm. Sensitivities and specificities of the generated classification trees were obtained by blindly applying data from set A to the generated trees from set B and vice versa. CRC serum protein profiles were also compared with those from breast, ovarian, prostate, and non-small cell lung cancer. RESULTS： Mass-to-charge ratios （m/z） 3.1×10^3, 3.3× 10^3, 4.5×10^3, 6.6×10^3 and 28×10^3 were used as classitiers in the best-performing classification trees. Tree sensitivities and specificities were between 65% and 90%.Host of these discriminative m/z values were also different in the other tumour types investigated. M/z 3.3× 10^3, main classifier in most trees, was a doubly charged form of the 6.6× 10^3-Da protein. The latter was identified as apolipoprotein C-I. M/z 3.1×10^3 was identified as an N-terminal fragment of albumin, and m/z 28× 10^3 as apolipoprotein A-I. CONCLUSION： SELDI-TOF MS followed by classification tree pattern analysis is a suitable technique for finding new serum markers for CRC. Biomarkers can be identified and reproducibly detected in independent sample sets with high sensitivities and specificities. Although not specific for CRC, these biomarkers have a potential role in disease and treatment monitoring.
文摘Previous works have shown that the suction probe cannot be used to accurately measure the upward and downward particle fluxes independently. A new method using a single optical probe to measure the local solid flux is presented. The measurement of upward, downward and net solid fluxes was carried out in a cold model circulating fluidized bed (CFB) unit. The result shows that the profile of the net solid flux is in good agreement with the previous experimental data measured with a suction probe. The comparison between the average solid flux determined with the optical measuring system and the external solid flux was made, and the maximum deviationturned out to be 22%, with the average error being about 6.9%. These confirm that the optical fiber system can be successfully used to measure the upward, downward and net solid fluxes simultaneously by correctly processing the sampling signals obtained from the optical measuring system.
文摘The bending modulus property of high performance fiber is an important property for both polymer science and engineering. The measurement of the bending performance is, however, difficult because of the thin size of the fiber. We have measured this property by the axial compression bending method where single fiber with suitable slenderness is compressed in the fiber axial direction to obtain the peak point of the force-displacement curve. Then the bending modulus and the flexural rigidity can be calculated by measuring the protruding length and diameter of fiber needles and the critical force, Pcr. The measured data show that the bending characteristics of all kinds of high performance fiber are dissimilar evidently.
文摘Today, micro-system technology and the development of new MEMS (Micro-Electro-Mechanical Systems) are emerging rapidly. In order for this development to become a success in the long run, measurement systems have to ensure product quality. Most often, MEMS have to be tested by means of functionality or destructive tests. One reason for this is that there are no suitable systems or sensing probes available which can be used for the measurement of quasi inaccessible features like small holes or cavities. We present a measurement system that could be used for these kinds of measurements. The system combines a fiber optical, miniaturized sensing probe with low-coherence interferometry, so that absolute distance measurements with nanometer accuracy are possible.
基金Supported by The National Institute of Health Grants BRP CA103830 and RO1 EB007594
文摘Recent advancements in the endoscopic imaging of Barrett's esophagus can be used to probe a wide range of optical properties that are altered with neoplastic progression.This review summarizes relevant changes in optical properties as well as imaging approaches that measures those changes.Wide-field imaging approaches include narrow-band imaging that measures changes in light scattering and absorption,and autofluorescence imaging that measure changes in endogenous fluorophores.High-resolution imaging approaches include optical coherence tomography,endocytoscopy,confocal microendoscopy,and high-resolution microendoscopy.These technologies,some coupled with an appropriate contrast agent,can measure differences in glandular morphology,nuclear morphology,or vascular alterations associated with neoplasia.Advances in targeted contrast agents are further discussed.Studies that have explored these technologies are highlighted;as are the advantages and limitations of each.
基金Project(20761002) supported by the National Natural Science Foundation of China
文摘Two novel ligands named 4-styrylpyridine-2,6-dicarboxylic acid (4-SPDA) and 4-(4-(2-(2, 6-dicarboxypyridin-4-yl)- vinyl)styryl)pyridine-2,6-dicarboxylic acid(DSPDA) and their complexes with Tb(Ⅲ) were synthesized and characterized by infrared spectrometry, 1H nuclear magnetic resonance, elemental analysis and gas chromatograph-mass spectrometry. The ligand synthetic route was optimized. The fluorescence properties of the complex in solid state, in different kind of solvents and in solutions with different pH values were investigated in detail. The results show that the yields of DSPDA and 4-SPDA reach over 78% by Wittig-Horner reaction and other eight pyridine-2, 6-dicarboxylic acid derivatives with different substituents on pyridine ring, and their complexes with Tb(Ⅲ) are also obtained. The fluorescence intensities of the complexes with electron-donating groups are more intense than those of the complexes with electron-withdrawing groups on pyridine ring; fluorescence intensities of the complexes are the strongest in neutral solution (pH=7), and the less the dipole moment of solvent molecule is, the stronger the fluorescence intensity is. It is found that the two ligands (4-APDA and DSPDA) are the good sensitizers for Tb(Ⅲ) ion.
基金Project(2003AA1Z2130)supported by the National High-Tech Research and Development Program of ChinaProject(2005C11001-02)supported by the Science and Technology Project of Zhejiang Province,China
文摘In order to obtain a compact and exact representation of 2D range scans,UKF(unscented Kalman filter) and CDKF(central difference Kalman filter) were proposed for extracting the breakpoint of the laser data. Line extraction was performed in every continuous breakpoint region by detecting the optimal angle and the optimal distance in polar coordinates,and every breakpoint area was constructed with two points. As a proof to the method,an experiment was performed by a mobile robot equipped with one SICK laser rangefinder,and the results of UKF/CDKF in breakpoint detection and line extraction were compared with those of the EKF(extended Kalman filter) . The results show that the exact geometry of the raw laser data of the environments can be obtained by segmented raw measurements(combining the proposed breakpoint detection approach with the line extraction method) ,and method UKF is the best one compared with CDKF and EKF.
文摘The rotatory optics element in the tensor dielectric coefficient matrix is an important para-(meter) for analyzing and calculating a rotatory optical fiber by electromagnetic theory. But the mea-(surement) of rotatory optics element is difficult for the rotatory optical fiber. A simple principle and method for measuring rotatory optics element are put forward in this paper. Firstly by using electromagnetic theory it was demonstrated that the rotatory optics element has a simple linear relation with the rotatory angle, and then the rotatory optics element has a simple linear relation with the magnetic field strength (or bias current in the helix coil) . Secondly a measurement system for the rotatory optics element in the rotatory optical fiber was designed. Using the measurement system the rotatory element can be obtained by measuring the bias current simply.
文摘As one of the interesting optical techniques for measurements of the velocity,the spatial filtering method is treated briefly in this paper.We shown theoretical analysis and calculation of spatial filtering velocimetry,and discussed two-dimensional measurements of the velocity.About the data processing,we used A/D conversion and interfaced with a microcomputer,so that the data can be processed automatically by the microcomputer.The preliminary experiment was performed and the experimental results show the usefulness of the present method for measurements of the velocity.
