分析了现有圆锥滚子轴承保持架结构特点和装配中存在的问题。基于筐形保持架的结构和轴承装配特点,将保持架窗孔设计成免扩张的结构,即改变原圆锥滚子轴承保持架窗孔形状,增大保持架窗孔靠近小端一侧宽度 K b2 ,窗孔大端宽度 K b1 、窗...分析了现有圆锥滚子轴承保持架结构特点和装配中存在的问题。基于筐形保持架的结构和轴承装配特点,将保持架窗孔设计成免扩张的结构,即改变原圆锥滚子轴承保持架窗孔形状,增大保持架窗孔靠近小端一侧宽度 K b2 ,窗孔大端宽度 K b1 、窗孔长度 L c与原保持架相同。经试验验证,装配后保持架仍然维持在原设计终加工状态,便于检验数据的可追溯性,保证了轴承游隙的稳定,提高了轴承的整体质量。展开更多
To determine whether the possession of certain HLA-DQA1 alleles was associated with the risk of developing idiopathic dilated cardiomyopathy (IDC) and to substantiate the role of an autoimmunologic pathogenesis in IDC...To determine whether the possession of certain HLA-DQA1 alleles was associated with the risk of developing idiopathic dilated cardiomyopathy (IDC) and to substantiate the role of an autoimmunologic pathogenesis in IDC. Type the alleles of HLA-DQA1 by polymerase chain reaction with sequence-specific primers (PCR-SSP) technique in 38 patients of idiopathic dilated cardiomyopathy (7 women and 31 men), aged from 17 to 56 years old with diagnosis being according to World Health Organization criteria (IDC group), in 50 patients of end-stage heart failure of known etiology (18 women and 32 men), with ages ranging from 34 to 72(HF group), and in the control group consisting of presumably 100 healthy subjects (39 women and 61 men) from the health survey, aged from 30 to 59 years old. The frequency of HLA-DQA1*0501 in the DCM patients was significantly elevated than that in the HF and the control group. Molecular analysis of the DQA1 gene polymorphism performed in the three subgroups shows an increased frequency of DQA1*0501 among patients with less EF. The HF group carries a high frequency of HLA-DQA1*0301. An increased frequency of DQA1*0201 and DQA1*0103 was found in the control group. HLA-DQA1*0501 is an associated gene of idiopathic dilated cardiomyopathy and the possession of DQA1*0301 may be indicative of the known etiologic heart failure, suggesting that the mechanisms involved in the pathogenesis of IDC and otherwise heart failure are different. Immunologic abnormalities may be a major contributor to the susceptibility of developing of IDC.展开更多
文摘分析了现有圆锥滚子轴承保持架结构特点和装配中存在的问题。基于筐形保持架的结构和轴承装配特点,将保持架窗孔设计成免扩张的结构,即改变原圆锥滚子轴承保持架窗孔形状,增大保持架窗孔靠近小端一侧宽度 K b2 ,窗孔大端宽度 K b1 、窗孔长度 L c与原保持架相同。经试验验证,装配后保持架仍然维持在原设计终加工状态,便于检验数据的可追溯性,保证了轴承游隙的稳定,提高了轴承的整体质量。
文摘To determine whether the possession of certain HLA-DQA1 alleles was associated with the risk of developing idiopathic dilated cardiomyopathy (IDC) and to substantiate the role of an autoimmunologic pathogenesis in IDC. Type the alleles of HLA-DQA1 by polymerase chain reaction with sequence-specific primers (PCR-SSP) technique in 38 patients of idiopathic dilated cardiomyopathy (7 women and 31 men), aged from 17 to 56 years old with diagnosis being according to World Health Organization criteria (IDC group), in 50 patients of end-stage heart failure of known etiology (18 women and 32 men), with ages ranging from 34 to 72(HF group), and in the control group consisting of presumably 100 healthy subjects (39 women and 61 men) from the health survey, aged from 30 to 59 years old. The frequency of HLA-DQA1*0501 in the DCM patients was significantly elevated than that in the HF and the control group. Molecular analysis of the DQA1 gene polymorphism performed in the three subgroups shows an increased frequency of DQA1*0501 among patients with less EF. The HF group carries a high frequency of HLA-DQA1*0301. An increased frequency of DQA1*0201 and DQA1*0103 was found in the control group. HLA-DQA1*0501 is an associated gene of idiopathic dilated cardiomyopathy and the possession of DQA1*0301 may be indicative of the known etiologic heart failure, suggesting that the mechanisms involved in the pathogenesis of IDC and otherwise heart failure are different. Immunologic abnormalities may be a major contributor to the susceptibility of developing of IDC.
