AIM:To investigate the spleen vascular involvement and the presence of liver fibrosis in a population of subjects with established systemic sclerosis(SSc).METHODS:In a cross-sectional fashion,17 patients with SSc were...AIM:To investigate the spleen vascular involvement and the presence of liver fibrosis in a population of subjects with established systemic sclerosis(SSc).METHODS:In a cross-sectional fashion,17 patients with SSc were compared with 18 patients suffering from hepatitis C virus(HCV) -related liver cirrhosis,grade A and B Child-Pugh classification.Eighteen non elderly subjects,apparently healthy,were used as the control group.Splenic artery resistivity index(SARI) at doppler ultraSound,transient elastography of liver and nailfold capillaroscopy were the main outcomes.RESULTS:Transient elastography values of SSc patients were similar to those of controls;5.2±1.1 vs 4.5 ±1,(P=0.07).Median Alanine amino transferase(ALT) concentrations of cirrhotic patients were greater than those of controls and SSc patients,i.e.66.5(36-89) U/L vs 29(22-34) U/L and 31(22-41) U/L,respectively,(P =0.005).SARI determinations in cirrhotic patients,although significantly higher than those found in controls and SSc patients,showed some degree of overlap with SSc patients,i.e.0.59 vs 0.52 and 0.57,respectively,(P =0.04).Mean systolic blood pressure was significantly higher in SSc patients than in cirrhotics and controls,i.e.142 mmHg vs 128.2 mmHg and 127 mmHg,respectively,(P=0.005).Mean diastolic blood pressure behaved in a similar fashion,i.e.84 mmHg vs 72.2 mmHg and 76.9 mmHg(P=0.005).Nailfold Capillaroscopy grades and diastolic blood pressure values correlated well with SARI results.CONCLUSION:An enhanced resistivity of the splenic artery was found in patients suffering from SSc;they did not have evidence of splenomegaly as well as no liver fibrosis or any other form of liver damage.展开更多
It is crucial to maintain wind turbine blades regularly, due to the high stress leading to defects or damage. Conventional methods require shipping the blades to a workshop for off-site inspection, which is extremely ...It is crucial to maintain wind turbine blades regularly, due to the high stress leading to defects or damage. Conventional methods require shipping the blades to a workshop for off-site inspection, which is extremely time-consuming and very costly. This work investigates the use of pulse-echo ultrasound to detect internal damages in wind turbine blades without the necessity to ship the blades off-site. A prototype 2D ultrasonic NDT （non-destructive testing） system has been developed and optimised for in-situ wind turbine blade inspection. The system is designed to be light weight so it can be easily carried by an inspector onto the wind turbine blade for in-situ inspection. It can be operated in 1D A-scan, 2D C-scan or 3D volume scan. A software system has been developed to control the automated scanning and show the damage areas in a 2D/3D map with different colours so that the inspector can easily identify the defective areas. Experiments on GFRP （glass fibre reinforced plastics） and wind turbine blades （made of GFRP） samples showed that internal defects can be detected. The main advantages of this system are fully automated 2D spatial scanning and the ability to alert the user to the damage of the inspected sample. It is intended to be used for in-situ inspection to save maintenance time and hence considered to be economically beneficial for the wind energy industry.展开更多
基金Supported by Funds of the Department of Clinical and Experimental Medicine of the Federico II University
文摘AIM:To investigate the spleen vascular involvement and the presence of liver fibrosis in a population of subjects with established systemic sclerosis(SSc).METHODS:In a cross-sectional fashion,17 patients with SSc were compared with 18 patients suffering from hepatitis C virus(HCV) -related liver cirrhosis,grade A and B Child-Pugh classification.Eighteen non elderly subjects,apparently healthy,were used as the control group.Splenic artery resistivity index(SARI) at doppler ultraSound,transient elastography of liver and nailfold capillaroscopy were the main outcomes.RESULTS:Transient elastography values of SSc patients were similar to those of controls;5.2±1.1 vs 4.5 ±1,(P=0.07).Median Alanine amino transferase(ALT) concentrations of cirrhotic patients were greater than those of controls and SSc patients,i.e.66.5(36-89) U/L vs 29(22-34) U/L and 31(22-41) U/L,respectively,(P =0.005).SARI determinations in cirrhotic patients,although significantly higher than those found in controls and SSc patients,showed some degree of overlap with SSc patients,i.e.0.59 vs 0.52 and 0.57,respectively,(P =0.04).Mean systolic blood pressure was significantly higher in SSc patients than in cirrhotics and controls,i.e.142 mmHg vs 128.2 mmHg and 127 mmHg,respectively,(P=0.005).Mean diastolic blood pressure behaved in a similar fashion,i.e.84 mmHg vs 72.2 mmHg and 76.9 mmHg(P=0.005).Nailfold Capillaroscopy grades and diastolic blood pressure values correlated well with SARI results.CONCLUSION:An enhanced resistivity of the splenic artery was found in patients suffering from SSc;they did not have evidence of splenomegaly as well as no liver fibrosis or any other form of liver damage.
文摘It is crucial to maintain wind turbine blades regularly, due to the high stress leading to defects or damage. Conventional methods require shipping the blades to a workshop for off-site inspection, which is extremely time-consuming and very costly. This work investigates the use of pulse-echo ultrasound to detect internal damages in wind turbine blades without the necessity to ship the blades off-site. A prototype 2D ultrasonic NDT （non-destructive testing） system has been developed and optimised for in-situ wind turbine blade inspection. The system is designed to be light weight so it can be easily carried by an inspector onto the wind turbine blade for in-situ inspection. It can be operated in 1D A-scan, 2D C-scan or 3D volume scan. A software system has been developed to control the automated scanning and show the damage areas in a 2D/3D map with different colours so that the inspector can easily identify the defective areas. Experiments on GFRP （glass fibre reinforced plastics） and wind turbine blades （made of GFRP） samples showed that internal defects can be detected. The main advantages of this system are fully automated 2D spatial scanning and the ability to alert the user to the damage of the inspected sample. It is intended to be used for in-situ inspection to save maintenance time and hence considered to be economically beneficial for the wind energy industry.
