Objective To observe the value of real-time shear wave elastography(SWE)combined with biochemical indicators for evaluating liver injury in patients with chronic kidney disease(CKD).Methods Totally 210 patients with C...Objective To observe the value of real-time shear wave elastography(SWE)combined with biochemical indicators for evaluating liver injury in patients with chronic kidney disease(CKD).Methods Totally 210 patients with CKD(CKD group)and 64 healthy subjects(control group)were retrospectively enrolled.Patients in CKD group were further divided into CKD1—5 subgroups according to CKD stages.SWE parameters of liver and kidney,including mean value,the maximum value and the median value of Young's modulus(EQI mean,EQI max and EQI med)were compared between CKD subgroups and control group.Spearman correlation analysis were performed to explore the correlations of liver and kidney SWE parameters with CKD stage,as well as of liver SWE parameters with biochemical indicators.Multivariate logistic regression analysis was used to screen independent predictors of liver injury in CKD patients.Receiver operating characteristic curves were drawn,the area under the curves(AUC)were calculated to evaluate the efficacy of the independent predictors alone and their combination for assessing liver injury in CKD patients.Results Significant differences of liver and kidney SWE parameters were found among CKD subgroups and control group(all P≤0.001).Pairwise comparison showed that liver SWE parameters in CKD5 subgroup and liver EQI max in CKD4 subgroup were all higher than those in control group(all P<0.003).Kidney SWE parameters in CKD3 subgroup were all higher than those in control group,while in CKD4 subgroup were all higher than those in control group and CKD1—3 subgroup(all P<0.003).Kidney EQI mean and EQI med in CKD5 subgroup were all higher than those in control group and CKD1—4 subgroup,while kidney EQI max in CKD5 subgroup were higher than those in control group and CKD1—3 subgroup(all P<0.003).Liver and kidney SWE parameters were lowly-moderately and positively correlated with CKD stages(r=0.364—0.665,all P<0.001).Liver SWE parameters of CKD were weakly and positively correlated with alkaline phosphatase(ALP)(r=0.229—0.248,all P<0.01).Theγ-glutamyl transferase,ALP and liver EQI max were all independent predictors of liver injury in CKD patients(all P<0.01),with AUC for evaluating liver injury in CKD patients alone of 0.645,0.756 and 0.741,respectively,lower than that of their combination(0.851,all P<0.01).Conclusion Real-time SWE combined with liver function indicators could reflect degree of liver injury in patients with different CKD stages.展开更多
Association rules are useful for determining correlations between items. Applying association rules to intrusion detection system (IDS) can improve the detection rate, but false positive rate is also increased. Weight...Association rules are useful for determining correlations between items. Applying association rules to intrusion detection system (IDS) can improve the detection rate, but false positive rate is also increased. Weighted association rules are used in this paper to mine intrustion models, which can increase the detection rate and decrease the false positive rate by some extent. Based on this, the structure of host-based IDS using weighted association rules is proposed.展开更多
The integrated linkage control problem based on attack detection is solved with the analyses of the security model including firewall, intrusion detection system （IDS） and vulnerability scan by game theory. The Nash...The integrated linkage control problem based on attack detection is solved with the analyses of the security model including firewall, intrusion detection system （IDS） and vulnerability scan by game theory. The Nash equilibrium for two portfolios of only deploying IDS and vulnerability scan and deploying all the technologies is investigated by backward induction. The results show that when the detection rates of IDS and vulnerability scan are low, the firm will not only inspect every user who raises an alarm, but also a fraction of users that do not raise an alarm; when the detection rates of IDS and vulnerability scan are sufficiently high, the firm will not inspect any user who does not raise an alarm, but only inspect a fraction of users that raise an alarm. Adding firewall into the information system impacts on the benefits of firms and hackers, but does not change the optimal strategies of hackers, and the optimal investigation strategies of IDS are only changed in certain cases. Moreover, the interactions between IDS ＆ vulnerability scan and firewall ＆ IDS are discussed in detail.展开更多
Through analyzing syntactic,semantic,pragmatic information,the retrieval system ACIS based on comprehensive information was established,which could achieve personalized information exaction to guide user s information...Through analyzing syntactic,semantic,pragmatic information,the retrieval system ACIS based on comprehensive information was established,which could achieve personalized information exaction to guide user s information retrieval.展开更多
文摘Objective To observe the value of real-time shear wave elastography(SWE)combined with biochemical indicators for evaluating liver injury in patients with chronic kidney disease(CKD).Methods Totally 210 patients with CKD(CKD group)and 64 healthy subjects(control group)were retrospectively enrolled.Patients in CKD group were further divided into CKD1—5 subgroups according to CKD stages.SWE parameters of liver and kidney,including mean value,the maximum value and the median value of Young's modulus(EQI mean,EQI max and EQI med)were compared between CKD subgroups and control group.Spearman correlation analysis were performed to explore the correlations of liver and kidney SWE parameters with CKD stage,as well as of liver SWE parameters with biochemical indicators.Multivariate logistic regression analysis was used to screen independent predictors of liver injury in CKD patients.Receiver operating characteristic curves were drawn,the area under the curves(AUC)were calculated to evaluate the efficacy of the independent predictors alone and their combination for assessing liver injury in CKD patients.Results Significant differences of liver and kidney SWE parameters were found among CKD subgroups and control group(all P≤0.001).Pairwise comparison showed that liver SWE parameters in CKD5 subgroup and liver EQI max in CKD4 subgroup were all higher than those in control group(all P<0.003).Kidney SWE parameters in CKD3 subgroup were all higher than those in control group,while in CKD4 subgroup were all higher than those in control group and CKD1—3 subgroup(all P<0.003).Kidney EQI mean and EQI med in CKD5 subgroup were all higher than those in control group and CKD1—4 subgroup,while kidney EQI max in CKD5 subgroup were higher than those in control group and CKD1—3 subgroup(all P<0.003).Liver and kidney SWE parameters were lowly-moderately and positively correlated with CKD stages(r=0.364—0.665,all P<0.001).Liver SWE parameters of CKD were weakly and positively correlated with alkaline phosphatase(ALP)(r=0.229—0.248,all P<0.01).Theγ-glutamyl transferase,ALP and liver EQI max were all independent predictors of liver injury in CKD patients(all P<0.01),with AUC for evaluating liver injury in CKD patients alone of 0.645,0.756 and 0.741,respectively,lower than that of their combination(0.851,all P<0.01).Conclusion Real-time SWE combined with liver function indicators could reflect degree of liver injury in patients with different CKD stages.
文摘Association rules are useful for determining correlations between items. Applying association rules to intrusion detection system (IDS) can improve the detection rate, but false positive rate is also increased. Weighted association rules are used in this paper to mine intrustion models, which can increase the detection rate and decrease the false positive rate by some extent. Based on this, the structure of host-based IDS using weighted association rules is proposed.
基金The National Natural Science Foundation of China(No.71071033)the Innovation Project of Jiangsu Postgraduate Education(No.CX10B_058Z)
文摘The integrated linkage control problem based on attack detection is solved with the analyses of the security model including firewall, intrusion detection system （IDS） and vulnerability scan by game theory. The Nash equilibrium for two portfolios of only deploying IDS and vulnerability scan and deploying all the technologies is investigated by backward induction. The results show that when the detection rates of IDS and vulnerability scan are low, the firm will not only inspect every user who raises an alarm, but also a fraction of users that do not raise an alarm; when the detection rates of IDS and vulnerability scan are sufficiently high, the firm will not inspect any user who does not raise an alarm, but only inspect a fraction of users that raise an alarm. Adding firewall into the information system impacts on the benefits of firms and hackers, but does not change the optimal strategies of hackers, and the optimal investigation strategies of IDS are only changed in certain cases. Moreover, the interactions between IDS ＆ vulnerability scan and firewall ＆ IDS are discussed in detail.
基金Supported by the National Natural Science Foundation of China(60575034)Science Foundation of Guangxi Provincial Education Department(200708LX322)~~
文摘Through analyzing syntactic,semantic,pragmatic information,the retrieval system ACIS based on comprehensive information was established,which could achieve personalized information exaction to guide user s information retrieval.
