Soil organic carbon (SOC) has great impacts on global warming, land degradation and food security. Classic statistical and geostatistical methods were used to characterize and compare the spatial heterogeneity of SOC ...Soil organic carbon (SOC) has great impacts on global warming, land degradation and food security. Classic statistical and geostatistical methods were used to characterize and compare the spatial heterogeneity of SOC and related factors, such as topography, soil type and land use, in the Liudaogou watershed on the Loess Plateau of North China. SOC concentrations followed a log-normal distribution with an arithmetic and geometric means of 23.4 and 21.3 g kg-1, respectively, were moderately variable (CV = 75.9%), and demonstrated a moderate spatial dependence according to the nugget ratio (34.7%). The experimental variogram of SOC was best-fitted by a spherical model, after the spatial outliers had been detected and subsequently eliminated. Lower SOC concentrations were associated with higher elevations. Warp soils and farmland had the highest SOC concentrations, while aeolian sand soil and shrublands had the lowest SOC values. The geostatistical characteristics of SOC for the different soil and land use types were different. These patterns were closely related to the spatial structure of topography, and soil and land use types.展开更多
Hepatitis B (HBV) and hepatitis C (HCV) viral infection or co-infection leads to risk of development of chronic infection, cirrhosis and hepatocellular carcinoma (HCC). Immigration and globalization have added t...Hepatitis B (HBV) and hepatitis C (HCV) viral infection or co-infection leads to risk of development of chronic infection, cirrhosis and hepatocellular carcinoma (HCC). Immigration and globalization have added to the challenges of public health concerns regarding chronic HBV and HCV infections worldwide. The aim of this study is to review existing global literature across ethnic populations on HBV and HCV related human leukocyte antigen (HLA) associations in relation to susceptibility, viral persistence and treatment. Extensive literature search was conducted to explore the HLA associations in HBV and HCV infections reported across global populations over the past decade to understand the knowledge status, weaknesses and strengths of this information in different ethnic populations. HLA DR13 is consistently associated with HBV clearance globally. HLADRB1*11/*12 alleles and DQB1*0301 are associated with HBV persistence but with HCV clearance worldwide. Consistent association of DRB1*03 and *07 is observed with HCV susceptibility and non-responsiveness to HBV vaccination across the population. HLA DR13 is protective for vertical HBV and HCV transmission in Chinese and Italian neonates, but different alleles are associated with their susceptibility in these populations. HLA class I molecule interactions with Killer cell immunoglobulin like receptors (KIR) of natural killer (NK) cells modulate HCV infection outcome via regulating immune regulatory cells and molecules. HLA associations with HBV vaccination, interferon therapy in HBV and HCV, and with extra hepatic manifestations of viral hepatitis are also discussed. Systematic studies in compliance with global regulatory standards are required to identify the HLA specific viral epitope, stage specific T cell populations interacting with different HLA alleles during disease progression and viral clearance of chronic HBV or HCV infections among different ethnic populations. These studies would facilitate stage specific therapeutic strategies for clearance of HBV and HCV infections or co-infections across global populations and aid in identification of HBV-HCV combined vaccine. HLA associations of chronic HBV or HCV development with confounding host factors including alcohol, drug abuse, insulin resistance, age and gender are lacking and warrant detailed investigation across global populations.展开更多
The influence of monsoon climatic characteristics makes the tropics of China different from those of other parts of the world. Therefore, the location of the northern boundary of China's tropical zone has been one...The influence of monsoon climatic characteristics makes the tropics of China different from those of other parts of the world. Therefore, the location of the northern boundary of China's tropical zone has been one of the most controversial issues in the study of comprehensive physical regionalisation in China. This paper introduces developments in the study of the northern boundary of China's tropical zone, in which different scholars delimit the boundary with great differences based on different regionalisation objectives, indexes, and methods. The main divergence of opinion is found in different understandings of zonal vegetation, agricultural vegetation type, cropping systems, tropical soil type and tropical characteristics. In this study, we applied the Geo Detector model, which measures the spatial stratified heterogeneity, to validate the northern boundaries of the tropical zone delimited by six principal scholars. The results show that the mean q-statistic value of the higher latitude boundary delimited by Ren Mei'e is the largest(q=0.37), suggesting that, of the rival views, it best reflects the regional differences between China's tropical and subtropical zones, but it is not necessarily suitable for guiding the development of tropical agriculture. The mean values of the q-statistics of Zheng Du's line and Yu Xianfang's line around the Leizhou Peninsula at a lower latitude were smaller, at 0.10 and 0.08 respectively, indicating that the regional differences were smaller than those of Ren Mei'e's boundary. Against the background of global climate change, the climate itself is changing in fluctuation. It is, thus, worth our further research whether the northern boundary of the tropical zone should not be a fixed line but rather should fluctuate within a certain scope to reflect these changes.展开更多
Research on the construction of a theory for China’s open economy should break through the limitations of mainstream Western international economics.Firstly,we need to reveal the laws revolving around"three rela...Research on the construction of a theory for China’s open economy should break through the limitations of mainstream Western international economics.Firstly,we need to reveal the laws revolving around"three relationships and six threads"that governed China’s incremental process of trade liberalization.Secondly,we need to summarize China’s experience of the way new technologies,including the Internet,digital technologies and artificial intelligence(AI)have fostered and reshaped the position of small and mediumsized enterprises(SMEs)as micro-actors,providing us with new advantages in international competition.Thirdly,we need to analyze the new win-win mode of the international division of labor over land and sea established under the guidelines of the Belt and Road Initiative(BRI),as well as a new concept of pluralist balance in the international economy marked by a close connection between trade surplus and foreign investment.Fourthly,under the guidance of Xi Jinping’s important discourses,we should offer a rationale for the Chinese scheme of global economy governance within the community of shared future for mankind.展开更多
基金Project supported by the National Key Basic Research Program (973 Program) of China (No.2007CB106803)the National Programs for Science and Technology Development of China (No.2006BAD09B06)the Scientific ResearchInnovation Team Support Program of the Northwest A&F University, China
文摘Soil organic carbon (SOC) has great impacts on global warming, land degradation and food security. Classic statistical and geostatistical methods were used to characterize and compare the spatial heterogeneity of SOC and related factors, such as topography, soil type and land use, in the Liudaogou watershed on the Loess Plateau of North China. SOC concentrations followed a log-normal distribution with an arithmetic and geometric means of 23.4 and 21.3 g kg-1, respectively, were moderately variable (CV = 75.9%), and demonstrated a moderate spatial dependence according to the nugget ratio (34.7%). The experimental variogram of SOC was best-fitted by a spherical model, after the spatial outliers had been detected and subsequently eliminated. Lower SOC concentrations were associated with higher elevations. Warp soils and farmland had the highest SOC concentrations, while aeolian sand soil and shrublands had the lowest SOC values. The geostatistical characteristics of SOC for the different soil and land use types were different. These patterns were closely related to the spatial structure of topography, and soil and land use types.
文摘Hepatitis B (HBV) and hepatitis C (HCV) viral infection or co-infection leads to risk of development of chronic infection, cirrhosis and hepatocellular carcinoma (HCC). Immigration and globalization have added to the challenges of public health concerns regarding chronic HBV and HCV infections worldwide. The aim of this study is to review existing global literature across ethnic populations on HBV and HCV related human leukocyte antigen (HLA) associations in relation to susceptibility, viral persistence and treatment. Extensive literature search was conducted to explore the HLA associations in HBV and HCV infections reported across global populations over the past decade to understand the knowledge status, weaknesses and strengths of this information in different ethnic populations. HLA DR13 is consistently associated with HBV clearance globally. HLADRB1*11/*12 alleles and DQB1*0301 are associated with HBV persistence but with HCV clearance worldwide. Consistent association of DRB1*03 and *07 is observed with HCV susceptibility and non-responsiveness to HBV vaccination across the population. HLA DR13 is protective for vertical HBV and HCV transmission in Chinese and Italian neonates, but different alleles are associated with their susceptibility in these populations. HLA class I molecule interactions with Killer cell immunoglobulin like receptors (KIR) of natural killer (NK) cells modulate HCV infection outcome via regulating immune regulatory cells and molecules. HLA associations with HBV vaccination, interferon therapy in HBV and HCV, and with extra hepatic manifestations of viral hepatitis are also discussed. Systematic studies in compliance with global regulatory standards are required to identify the HLA specific viral epitope, stage specific T cell populations interacting with different HLA alleles during disease progression and viral clearance of chronic HBV or HCV infections among different ethnic populations. These studies would facilitate stage specific therapeutic strategies for clearance of HBV and HCV infections or co-infections across global populations and aid in identification of HBV-HCV combined vaccine. HLA associations of chronic HBV or HCV development with confounding host factors including alcohol, drug abuse, insulin resistance, age and gender are lacking and warrant detailed investigation across global populations.
基金National Natural Science Foundation of China,No.41371030
文摘The influence of monsoon climatic characteristics makes the tropics of China different from those of other parts of the world. Therefore, the location of the northern boundary of China's tropical zone has been one of the most controversial issues in the study of comprehensive physical regionalisation in China. This paper introduces developments in the study of the northern boundary of China's tropical zone, in which different scholars delimit the boundary with great differences based on different regionalisation objectives, indexes, and methods. The main divergence of opinion is found in different understandings of zonal vegetation, agricultural vegetation type, cropping systems, tropical soil type and tropical characteristics. In this study, we applied the Geo Detector model, which measures the spatial stratified heterogeneity, to validate the northern boundaries of the tropical zone delimited by six principal scholars. The results show that the mean q-statistic value of the higher latitude boundary delimited by Ren Mei'e is the largest(q=0.37), suggesting that, of the rival views, it best reflects the regional differences between China's tropical and subtropical zones, but it is not necessarily suitable for guiding the development of tropical agriculture. The mean values of the q-statistics of Zheng Du's line and Yu Xianfang's line around the Leizhou Peninsula at a lower latitude were smaller, at 0.10 and 0.08 respectively, indicating that the regional differences were smaller than those of Ren Mei'e's boundary. Against the background of global climate change, the climate itself is changing in fluctuation. It is, thus, worth our further research whether the northern boundary of the tropical zone should not be a fixed line but rather should fluctuate within a certain scope to reflect these changes.
文摘Research on the construction of a theory for China’s open economy should break through the limitations of mainstream Western international economics.Firstly,we need to reveal the laws revolving around"three relationships and six threads"that governed China’s incremental process of trade liberalization.Secondly,we need to summarize China’s experience of the way new technologies,including the Internet,digital technologies and artificial intelligence(AI)have fostered and reshaped the position of small and mediumsized enterprises(SMEs)as micro-actors,providing us with new advantages in international competition.Thirdly,we need to analyze the new win-win mode of the international division of labor over land and sea established under the guidelines of the Belt and Road Initiative(BRI),as well as a new concept of pluralist balance in the international economy marked by a close connection between trade surplus and foreign investment.Fourthly,under the guidance of Xi Jinping’s important discourses,we should offer a rationale for the Chinese scheme of global economy governance within the community of shared future for mankind.