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异氟醚全麻作用的分子机制 被引量:4
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作者 靳艳卿 《国外医学(麻醉学与复苏分册)》 2000年第3期174-177,共4页
异氟醚全麻作用的分子机制仍不十分清楚。目前认为异氟醚主要是通过直接作用于神经细胞膜上的蛋白质发挥全麻作用的。其中包括增强GABA_A受体的功能,抑制电压门控性钠通道和钙通道,激活电压门控性钾通道,使突触间隙中抑制性神经递质的... 异氟醚全麻作用的分子机制仍不十分清楚。目前认为异氟醚主要是通过直接作用于神经细胞膜上的蛋白质发挥全麻作用的。其中包括增强GABA_A受体的功能,抑制电压门控性钠通道和钙通道,激活电压门控性钾通道,使突触间隙中抑制性神经递质的含量增多、兴奋性神经递质的含量减少,影响胞内第二信使系统等。 展开更多
关键词 异氟醚 全麻作用 分子机制
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喉罩七氟醚吸入在小儿眼科手术麻醉中的应用 被引量:26
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作者 费建 蒋文旭 《临床麻醉学杂志》 CAS CSCD 2008年第12期1076-1076,共1页
关键词 手术麻醉 小儿眼科 七氟醚 喉罩 吸入 保留自主呼吸 临床麻醉 全麻作用
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氯胺酮的临床应用
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作者 王学夫 《中国热带医学》 CAS 2006年第4期700-701,共2页
关键词 临床应用 氯胺酮 静脉麻醉药 全身麻醉 临床使用 遗忘作用 镇痛效能 麻醉作用 全麻作用 KET
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吸入麻醉药对心肌收缩力的抑制作用
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作者 宋小星 彭章龙 于布为 《国际麻醉学与复苏杂志》 CAS 2006年第5期300-302,共3页
The negative inotropic action of volatile anesthetics has been attributed to the effect on various cellular components.For example,volatile anesthetics can not only inhibit L-type Ca2+ current and shorten the action p... The negative inotropic action of volatile anesthetics has been attributed to the effect on various cellular components.For example,volatile anesthetics can not only inhibit L-type Ca2+ current and shorten the action potential,but also effect the Ca2+ sensitivity of contractile proteins.Furthermore,volatile anesthetics can decrease sarcoplasmic reticulum Ca2+ content,and inhibit fractional SR Ca2+ release,thus decrease the contractile force of cardiac muscles.And the inhibition is related to the concentration of volatile anesthetics. 展开更多
关键词 心肌收缩力 吸入麻醉药 抑制作用 负性肌力作用 全麻作用 安氟醚 七氟醚 异氟醚
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Effect of acupoint massage plus acupoint sticking therapy for the stress reaction during postoperative anesthesia recovery period in patients undergoing nasal endoscopic surgery 被引量:4
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作者 陆伟钰 沈娟芬 +2 位作者 沈丽萍 朱建芬 贾一凡 《Journal of Acupuncture and Tuina Science》 CSCD 2018年第5期343-348,共6页
Objective:To observe the effect of acupoint massage plus acupoint sticking therapy for the stress reaction during postoperative anesthesia recovery period in patients undergoing nasal endoscopic surgery.Methods:A tota... Objective:To observe the effect of acupoint massage plus acupoint sticking therapy for the stress reaction during postoperative anesthesia recovery period in patients undergoing nasal endoscopic surgery.Methods:A total of 120 patients undergoing nasal endoscopic surgery were included,and all patients were under trachea intubation and general anesthesia.The patients were randomized into an observation group and a control group,with 60 patients in each group.Patients in the control group received conventional anesthesia resuscitation,while patients in the observation group received acupoint massage plus acupoint sticking therapy on the basis of conventional anesthesia resuscitation.Changes in the heart rate (HR),systolic blood pressure (SBP) and diastolic blood pressure (DBP) were observed at three time points including the end of the surgery (TO),the removal of the tracheal tube (T1) and 10 min after the removal of the tracheal tube (T2).The awakening and tube removal time,choking cough and restlessness,and adverse reactions (dizziness,nausea and vomiting) in 24 h post-surgery period were compared.Results:At T1 and T2,the comparisons of HR,SBP and DBP between the two groups showed statistical significance (all P<0.05).Intra-group comparisons showed that the HR,SBP and DBP of the control group at T1 and T2 were significant different from those at TO (all P<0.05).There were significant differences in the awakening time and tube removal time between the two groups (both P<0.05).The incidences of choking cough and restlessness were 8.3% and 3.3% respectively in the observation group,versus 53.3% and 30.0% in the control group,and the between-group comparisons showed statistical significance (both P<0.05).The incidences of dizziness,nausea and vomiting in 24 h post-surgery period were 3.3%,5.0% and 0.0% respectively in the observation group,versus 43.3%,33.3% and 25.0% in the control group,and the between-group comparisons showed statistical significance (all P<0.05).Conclusion:Acupoint massage plus acupoint sticking therapy can effectively regulate the stress reaction during postoperative anesthesia recovery period in patients undergoing nasal endoscopic surgery,and maintain a stable internal environment. 展开更多
关键词 TUINA MASSAGE Acupoint Sticking Therapy Nasal Surgical Procedures Anesthesia Recovery Period Anesthesia General Drug-related Side Effects and Adverse Reaction
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