Boehmite nanoparticles with a high surface area and a high degree of surface hydroxyl groups were covalently functionalized by 3‐（trimethoxysilyl）‐propylamine to support vanadium‐oxo‐sulfate and molybdenum hexac...Boehmite nanoparticles with a high surface area and a high degree of surface hydroxyl groups were covalently functionalized by 3‐（trimethoxysilyl）‐propylamine to support vanadium‐oxo‐sulfate and molybdenum hexacarbonyl complexes. These supported catalysts were then characterized by Fou‐rier‐transform infrared spectroscopy, powder X‐ray diffraction, thermogravimetry and differential thermal analysis, X‐ray‐photoelectron spectroscopy, elemental analysis, inductively coupled plasma, and transmission electron microscopy techniques. The catalysts were subsequently used for the epoxidation of cis‐cyclooctene, and the experimental procedures were optimized. The progress of the reactions was investigated by gas‐liquid chromatography. Recycling experiments revealed that these nanocatalysts could be repeatedly used several times for a nearly complete epoxidation of cis‐cyclooctene. The optimized experimental conditions were also used successfully for the epoxida‐tion of some other substituted alkenes.展开更多
Objective To explore the transitive regularity of holistic constituents from the crude slices of the medicinal raw materials(MCS)to the formula granules(FG),fufang decoction(FD),and finally,the concentrated pills(CP)o...Objective To explore the transitive regularity of holistic constituents from the crude slices of the medicinal raw materials(MCS)to the formula granules(FG),fufang decoction(FD),and finally,the concentrated pills(CP)of Liuwei Dihuang Fufang(六味地黄复方,LWDHF).Methods Samples for MCS,FG,FD,and CP of LWDHF were obtained,and a fingerprint data-base was established using high-performance liquid chromatography(HPLC),by separating the samples in an XB-C18 column and analyzing the transitive regularity of components us-ing the total quantum statistical moment(TQSM),including total quantum zero moment(AUCT),total quantum first moment(MRTT),total quantum second moment(VRTT),and its similarity approach.The AUCT,MRTT,and VRTT were calculated based on the representative HPLC chromatograms of FG,FD,and CP of LWDHF.Results AUCT of FG,FD,and CP of LWDHF was 71804,46553,and 144646μV·s,respectively;MRTT was 14.43,14.54,and 18.85 min,respectively;and VRTT was 106.98,112.84,and 269.12 min2,respectively.Comparing the similarity of FG/FD,FG/CP and FD/CP of LWDHF,the TQSM similarity values were 98.66%,76.62%,and 75.37%,respectively,whereas the tradi-tional similarity evaluation values were 98.68%,85.43%,and 85.60%,respectively.Conclusion The results perform little distinction in the total composition between FG and FD,whereas some distinction existed between FD and CP.Experimental evidence,therefore indicates that FG could be used as the alternative of MCS in clinical applications.展开更多
基金the vice-president's office for research affairs of Shahrood University of Technology for the financial support of this work
文摘Boehmite nanoparticles with a high surface area and a high degree of surface hydroxyl groups were covalently functionalized by 3‐（trimethoxysilyl）‐propylamine to support vanadium‐oxo‐sulfate and molybdenum hexacarbonyl complexes. These supported catalysts were then characterized by Fou‐rier‐transform infrared spectroscopy, powder X‐ray diffraction, thermogravimetry and differential thermal analysis, X‐ray‐photoelectron spectroscopy, elemental analysis, inductively coupled plasma, and transmission electron microscopy techniques. The catalysts were subsequently used for the epoxidation of cis‐cyclooctene, and the experimental procedures were optimized. The progress of the reactions was investigated by gas‐liquid chromatography. Recycling experiments revealed that these nanocatalysts could be repeatedly used several times for a nearly complete epoxidation of cis‐cyclooctene. The optimized experimental conditions were also used successfully for the epoxida‐tion of some other substituted alkenes.
基金Hunan Provincial Natural Science Foundation of China(2019JJ40220 and 2021JJ30514)Hunan Provincial Administration of Traditional Chinese Medicine(2021204and 2021073)+1 种基金Scientific Research Fund of Hunan Provincial Education Department(2021204 and 2021073)Pharmaceutical Open Fund of Domestic First-class Disciplines(Cultivation)of Hunan Province(2018YX11)。
文摘Objective To explore the transitive regularity of holistic constituents from the crude slices of the medicinal raw materials(MCS)to the formula granules(FG),fufang decoction(FD),and finally,the concentrated pills(CP)of Liuwei Dihuang Fufang(六味地黄复方,LWDHF).Methods Samples for MCS,FG,FD,and CP of LWDHF were obtained,and a fingerprint data-base was established using high-performance liquid chromatography(HPLC),by separating the samples in an XB-C18 column and analyzing the transitive regularity of components us-ing the total quantum statistical moment(TQSM),including total quantum zero moment(AUCT),total quantum first moment(MRTT),total quantum second moment(VRTT),and its similarity approach.The AUCT,MRTT,and VRTT were calculated based on the representative HPLC chromatograms of FG,FD,and CP of LWDHF.Results AUCT of FG,FD,and CP of LWDHF was 71804,46553,and 144646μV·s,respectively;MRTT was 14.43,14.54,and 18.85 min,respectively;and VRTT was 106.98,112.84,and 269.12 min2,respectively.Comparing the similarity of FG/FD,FG/CP and FD/CP of LWDHF,the TQSM similarity values were 98.66%,76.62%,and 75.37%,respectively,whereas the tradi-tional similarity evaluation values were 98.68%,85.43%,and 85.60%,respectively.Conclusion The results perform little distinction in the total composition between FG and FD,whereas some distinction existed between FD and CP.Experimental evidence,therefore indicates that FG could be used as the alternative of MCS in clinical applications.
