Mycobacterium tuberculosis(M.tb) and human immunodeficiency virus(HIV) co-infection has become a public health issue worldwide. Up to now, there have been many unresolved issues either in the clinical diagnosis and tr...Mycobacterium tuberculosis(M.tb) and human immunodeficiency virus(HIV) co-infection has become a public health issue worldwide. Up to now, there have been many unresolved issues either in the clinical diagnosis and treatment of M.tb/HIV coinfection or in the basic understanding of the mechanisms for the impairments to the immune system by interactions of these two pathogens. One important reason for these unsolved issues is the lack of appropriate animal models for the study of M.tb/HIV coinfection. This paper reviews the recent development of research on the animal models of M.tb/HIV co-infection, with a focus on the non-human primate models.展开更多
Due to quick changes of the market and long supply chain, it is difficult for clothing enterprises to make timely and correct production adjustment. According China＇ s data, research of this paper indicates that the ...Due to quick changes of the market and long supply chain, it is difficult for clothing enterprises to make timely and correct production adjustment. According China＇ s data, research of this paper indicates that the correctness of clothing enterprises adjustment is only about 43%. Some positive actions can improve the condition, such as set up the quick feedback way of the market information, improve information sharing by cooperation mechanism of upstream and downstream in the industry or cross industry, and strengthen the regulatory mechanism of production.展开更多
基金supported by grants from the National Natural Sciences Foundation of China(81201261,81301428)the National Science Foundation for Post-doctoral Scientists of China(2013M5317456)the National Science and Technology Major Project of the Ministry of Science and Technology of China(2012ZX10004501-001-004)
文摘Mycobacterium tuberculosis(M.tb) and human immunodeficiency virus(HIV) co-infection has become a public health issue worldwide. Up to now, there have been many unresolved issues either in the clinical diagnosis and treatment of M.tb/HIV coinfection or in the basic understanding of the mechanisms for the impairments to the immune system by interactions of these two pathogens. One important reason for these unsolved issues is the lack of appropriate animal models for the study of M.tb/HIV coinfection. This paper reviews the recent development of research on the animal models of M.tb/HIV co-infection, with a focus on the non-human primate models.
文摘Due to quick changes of the market and long supply chain, it is difficult for clothing enterprises to make timely and correct production adjustment. According China＇ s data, research of this paper indicates that the correctness of clothing enterprises adjustment is only about 43%. Some positive actions can improve the condition, such as set up the quick feedback way of the market information, improve information sharing by cooperation mechanism of upstream and downstream in the industry or cross industry, and strengthen the regulatory mechanism of production.
