Photocatalytic H2evolution under visible light irradiation is an ideal process for solving energy shortage.The low cost of photocatalysts and high efficiency of hydrogen evolution are the two key factors to realize th...Photocatalytic H2evolution under visible light irradiation is an ideal process for solving energy shortage.The low cost of photocatalysts and high efficiency of hydrogen evolution are the two key factors to realize the industrialization of the process.The substitution of a noble‐metal cocatalyst with a non‐noble‐metal catalyst can significantly reduce the cost of the photocatalyst.The largescale synthesis and assembly of semiconductors and non‐noble‐metal cocatalysts to form photocatalysts through a simple method can further decrease the cost of photocatalysis.Here,we report a large‐scale and low‐cost coprecipitation method to form phosphide/CdS photocatalysts to realize photocatalytic H2evolution.CoP and MoP cocatalysts significantly enhanced the photocatalytic production of hydrogen.The optimal H2production rates on CoP/CdS and MoP/CdS were140and78μmol/h,which were7.0and4.0times higher than those obtained with bare CdS,respectively,and2.0times and1.1times higher than those obtained with1.0%Pt/CdS,respectively.This work provides a practical method for the large‐scale preparation of low‐cost photocatalysts.展开更多
We propose a new multiparty quantum secret sharing protocol via introducing auxiliary particles using a non-maximally entangled （pure） two-particle state without a Bell measurement. The communication parties utilize...We propose a new multiparty quantum secret sharing protocol via introducing auxiliary particles using a non-maximally entangled （pure） two-particle state without a Bell measurement. The communication parties utilize decoy particles tO check eavesdropping. After ensuring the security of the quantum channel, the sender encodes the secret message and transmits it to the receiver by using controlled-NOT operation and von Neumann measurement. If and only if all the agents agree to collaborate, they can read out the secret message.展开更多
Porous silicon(PSi)was applied as a supporting substrate for stepwise covalent derivatization of undecylenic acid, N-hydroxysuccinimidyl ester(NHS-ester)and nitrilotriacetic acid(NTA).By taking the advantages of porou...Porous silicon(PSi)was applied as a supporting substrate for stepwise covalent derivatization of undecylenic acid, N-hydroxysuccinimidyl ester(NHS-ester)and nitrilotriacetic acid(NTA).By taking the advantages of porous silicon as a supporting matrix such as high surface area to volume ratio,infrared transparency,porous semiconductors for laser desorption/ionization mass spectroscopy,and low fluorescence background,a multi-mode detection biochip prototype can be realized. We prepared such a protein microarray by spotting NTA microarray dots on NHS-ester derivatized PSi,converting the rest of chip area into poly(ethylene glycol)background,loading NiII,and finally affinity-binding histidine-tagged(His-tagged)proteins.With the multi-mode analyses of infrared spectroscopy,X-ray photoelectron spectroscopy(XPS),atomic force microscopy(AFM),matrix-assisted laser desorption/ionization mass spectroscopy(MALDI-MS),and fluorescence scanning,two example proteins,His-tagged thioredoxin-urodilatin and His-tagged aprotinin,were well qualified and quantified.展开更多
A new series of sulfonamide flavone derivatives are designed as non-covalent inhibitors of proteasome assisted with computer-aided drug design （CADD）. The desired compounds were synthesized successfully and the biol...A new series of sulfonamide flavone derivatives are designed as non-covalent inhibitors of proteasome assisted with computer-aided drug design （CADD）. The desired compounds were synthesized successfully and the biological evaluation was subsequently accomplished. The results showed negligible improvement from our lead compound （IC50 for β5 subunit was 14.0 μM）. Thus, these flavone derivatives might be improved as potential 20S proteasome inhibitors.展开更多
Objective.This study aimed to compare the accuracy of rectal cancer restaging after neoadjuvant therapy with 3D CUBE sequence with 2D T2-weighted fast spin-echo(FSE)sequence.Methods.This retrospective study comprised ...Objective.This study aimed to compare the accuracy of rectal cancer restaging after neoadjuvant therapy with 3D CUBE sequence with 2D T2-weighted fast spin-echo(FSE)sequence.Methods.This retrospective study comprised 72 patients with rectal cancer confirmed by colonoscopy and biopsy.After neoadjuvant therapy,all patients underwent pelvic magnetic resonance imaging(MRI)examination at 1.5T MRI sequences including a single coronal 3D CUBE T2-weighted FSE sequence with 1.4mmthickness and a 2D T2-weighted FSE sequence in the sagittal,coronal and axial planes with 5mmthickness.The total acquisition time of the two sequences was recorded.Results were compared with postsurgical pathology(gold standard).The diagnostic accuracy was evaluated;and receiver operating characteristic(ROC)curves and the area under the curves(AUC)were calculated.Results.The T category staging accuracy of 3D T2WI and 2D T2WI was 81.9% and 72.2%,respectively,for reviewer 1 and 86.1% and 75.0% for reviewer 2.The AUC of 3D was higher than that of 2D(0.878 vs.0.783 for reader 1 and 0.905 vs.0.796 for reader 2;both P<0.05)when judging whether the tumor broke through themuscle layer.There was no significant difference between 3D and 2D in judging whether lymph nodes weremalignant(AUC 0.719 vs.0.698 for reader 1 and 0.740 vs.0.698 for reader 2;both P>0.05).There were no significant differences in the visibility of the rectal wall layer,tumor lesion and the overall image quality(all P>0.05).Compared with 2D sequences,the 3D sequence had shorter acquisition time and higher signal intensity ratio(both P<0.05).Conclusion.3D CUBE T2-weighted sequences offer better diagnostic accuracy in rectal cancer restaging after neoadjuvant therapy when compared with 2D T2-weighted FSE sequences;it has a shorter scanning time and more versatility of orientation reconstruction.展开更多
基金supported by the National First-rate Discipline Construction Project of Ningxia (Chemical Engineering and Technology)the Major Innovation Projects for Building First-class Universities in China’s Western Region (ZKZD2017003)+2 种基金the University Research Project of Ningxia (NGY2015027)the National Natural Science Foundation of China (21263018)the Project of Science and Technology of Personnel of Study Abroad (Ningxia (2014) 486)~~
文摘Photocatalytic H2evolution under visible light irradiation is an ideal process for solving energy shortage.The low cost of photocatalysts and high efficiency of hydrogen evolution are the two key factors to realize the industrialization of the process.The substitution of a noble‐metal cocatalyst with a non‐noble‐metal catalyst can significantly reduce the cost of the photocatalyst.The largescale synthesis and assembly of semiconductors and non‐noble‐metal cocatalysts to form photocatalysts through a simple method can further decrease the cost of photocatalysis.Here,we report a large‐scale and low‐cost coprecipitation method to form phosphide/CdS photocatalysts to realize photocatalytic H2evolution.CoP and MoP cocatalysts significantly enhanced the photocatalytic production of hydrogen.The optimal H2production rates on CoP/CdS and MoP/CdS were140and78μmol/h,which were7.0and4.0times higher than those obtained with bare CdS,respectively,and2.0times and1.1times higher than those obtained with1.0%Pt/CdS,respectively.This work provides a practical method for the large‐scale preparation of low‐cost photocatalysts.
基金National Natural Science Foundation of China under Grant No.10575017
文摘We propose a new multiparty quantum secret sharing protocol via introducing auxiliary particles using a non-maximally entangled （pure） two-particle state without a Bell measurement. The communication parties utilize decoy particles tO check eavesdropping. After ensuring the security of the quantum channel, the sender encodes the secret message and transmits it to the receiver by using controlled-NOT operation and von Neumann measurement. If and only if all the agents agree to collaborate, they can read out the secret message.
基金the financial support of the National Basic Research Program of China(2007CB925101)the National Natural Science Foundation of China(20721002&20827001)an open research fund of State Key Laboratory of Bioelectronics,Southeast University
文摘Porous silicon(PSi)was applied as a supporting substrate for stepwise covalent derivatization of undecylenic acid, N-hydroxysuccinimidyl ester(NHS-ester)and nitrilotriacetic acid(NTA).By taking the advantages of porous silicon as a supporting matrix such as high surface area to volume ratio,infrared transparency,porous semiconductors for laser desorption/ionization mass spectroscopy,and low fluorescence background,a multi-mode detection biochip prototype can be realized. We prepared such a protein microarray by spotting NTA microarray dots on NHS-ester derivatized PSi,converting the rest of chip area into poly(ethylene glycol)background,loading NiII,and finally affinity-binding histidine-tagged(His-tagged)proteins.With the multi-mode analyses of infrared spectroscopy,X-ray photoelectron spectroscopy(XPS),atomic force microscopy(AFM),matrix-assisted laser desorption/ionization mass spectroscopy(MALDI-MS),and fluorescence scanning,two example proteins,His-tagged thioredoxin-urodilatin and His-tagged aprotinin,were well qualified and quantified.
基金The National Natural Science Foundation of China(Grant No.21202003)the National Basic Research Program of China(Grant No.2012CB518000)the Specialized Research Fund for the Doctoral Program of Higher Education of China(Grant No.20120001110010)
文摘A new series of sulfonamide flavone derivatives are designed as non-covalent inhibitors of proteasome assisted with computer-aided drug design （CADD）. The desired compounds were synthesized successfully and the biological evaluation was subsequently accomplished. The results showed negligible improvement from our lead compound （IC50 for β5 subunit was 14.0 μM）. Thus, these flavone derivatives might be improved as potential 20S proteasome inhibitors.
基金This study was supported by grants from the Guangdong Science and Technology Department of China(No.2015A030313109).
文摘Objective.This study aimed to compare the accuracy of rectal cancer restaging after neoadjuvant therapy with 3D CUBE sequence with 2D T2-weighted fast spin-echo(FSE)sequence.Methods.This retrospective study comprised 72 patients with rectal cancer confirmed by colonoscopy and biopsy.After neoadjuvant therapy,all patients underwent pelvic magnetic resonance imaging(MRI)examination at 1.5T MRI sequences including a single coronal 3D CUBE T2-weighted FSE sequence with 1.4mmthickness and a 2D T2-weighted FSE sequence in the sagittal,coronal and axial planes with 5mmthickness.The total acquisition time of the two sequences was recorded.Results were compared with postsurgical pathology(gold standard).The diagnostic accuracy was evaluated;and receiver operating characteristic(ROC)curves and the area under the curves(AUC)were calculated.Results.The T category staging accuracy of 3D T2WI and 2D T2WI was 81.9% and 72.2%,respectively,for reviewer 1 and 86.1% and 75.0% for reviewer 2.The AUC of 3D was higher than that of 2D(0.878 vs.0.783 for reader 1 and 0.905 vs.0.796 for reader 2;both P<0.05)when judging whether the tumor broke through themuscle layer.There was no significant difference between 3D and 2D in judging whether lymph nodes weremalignant(AUC 0.719 vs.0.698 for reader 1 and 0.740 vs.0.698 for reader 2;both P>0.05).There were no significant differences in the visibility of the rectal wall layer,tumor lesion and the overall image quality(all P>0.05).Compared with 2D sequences,the 3D sequence had shorter acquisition time and higher signal intensity ratio(both P<0.05).Conclusion.3D CUBE T2-weighted sequences offer better diagnostic accuracy in rectal cancer restaging after neoadjuvant therapy when compared with 2D T2-weighted FSE sequences;it has a shorter scanning time and more versatility of orientation reconstruction.
