The incidence of hepatocellular carcinoma(HCC)is increasing in the United States,and 50%-75%o patients with HCC will develop metastatic disease Orbital metastases from HCC are extremely rare.We report the case of a 52...The incidence of hepatocellular carcinoma(HCC)is increasing in the United States,and 50%-75%o patients with HCC will develop metastatic disease Orbital metastases from HCC are extremely rare.We report the case of a 52-year-old male with known metastatic HCC,who presented with severe proptosis and diplopia.An orbital mass was identified on magnetic resonance imaging(MRI)and confirmed to have hypermetabolic activity on positron emission tomography/computed tomography.He received a palliative course of external beam radiation therapy to the right orbit.Intensity modulated radiation therapy (IMRT)was used to allow sparing of critical norma tissues in close proximity to the tumor.One month after completion of IMRT to 58 Gray in 30 fractions delivered over 6 wk,the patient had a complete clinical,radiologic(MRI)and symptomatic response The patient continues to have local control in the orbi 1.7 years after therapy completion.All critical norma structures were kept below the tolerance dose using IMRT,and no toxicities were observed.展开更多
Obliquely incident water wave scattering by an uneven channel-bed in the form of a small bottom undulation in a two-layer fluid is investigated within the frame work of three-dimensional linear water wave theory. The ...Obliquely incident water wave scattering by an uneven channel-bed in the form of a small bottom undulation in a two-layer fluid is investigated within the frame work of three-dimensional linear water wave theory. The upper fluid is assumed to be bounded above by a rigid lid, while the lower one is bounded below by a bottom surface having a small deformation and the channel is unbounded in the horizontal directions. Assuming irrotational motion, perturbation technique is employed to calculate the first-order corrections to the velocity potentials in the two fluids by using Fourier transform approximately, and also to calculate the reflection and transmission coefficients in terms of integrals involving the shape function representing the bottom deformation. Consideration of a patch of sinusoidal ripples shows that the reflection coefficient is an oscillatory function of the ratio of twice the component of the wave number along x-axis and the ripple wave number. When this ratio approaches one, the theory predicts a resonant interaction between the bed and interface, and the reflection coefficient becomes a multiple of the number of ripples. High reflection of incident wave energy occurs if this number is large.展开更多
文摘The incidence of hepatocellular carcinoma(HCC)is increasing in the United States,and 50%-75%o patients with HCC will develop metastatic disease Orbital metastases from HCC are extremely rare.We report the case of a 52-year-old male with known metastatic HCC,who presented with severe proptosis and diplopia.An orbital mass was identified on magnetic resonance imaging(MRI)and confirmed to have hypermetabolic activity on positron emission tomography/computed tomography.He received a palliative course of external beam radiation therapy to the right orbit.Intensity modulated radiation therapy (IMRT)was used to allow sparing of critical norma tissues in close proximity to the tumor.One month after completion of IMRT to 58 Gray in 30 fractions delivered over 6 wk,the patient had a complete clinical,radiologic(MRI)and symptomatic response The patient continues to have local control in the orbi 1.7 years after therapy completion.All critical norma structures were kept below the tolerance dose using IMRT,and no toxicities were observed.
基金partially supported by a research grant from Department of Science and Technology(DST),India(No.SB/FTP/MS-003/2013)
文摘Obliquely incident water wave scattering by an uneven channel-bed in the form of a small bottom undulation in a two-layer fluid is investigated within the frame work of three-dimensional linear water wave theory. The upper fluid is assumed to be bounded above by a rigid lid, while the lower one is bounded below by a bottom surface having a small deformation and the channel is unbounded in the horizontal directions. Assuming irrotational motion, perturbation technique is employed to calculate the first-order corrections to the velocity potentials in the two fluids by using Fourier transform approximately, and also to calculate the reflection and transmission coefficients in terms of integrals involving the shape function representing the bottom deformation. Consideration of a patch of sinusoidal ripples shows that the reflection coefficient is an oscillatory function of the ratio of twice the component of the wave number along x-axis and the ripple wave number. When this ratio approaches one, the theory predicts a resonant interaction between the bed and interface, and the reflection coefficient becomes a multiple of the number of ripples. High reflection of incident wave energy occurs if this number is large.
