[ Objective] This study is to provide basis for the genetic improvement of triploid watermelon cultivars from seed coat characteristiscs by analyzing its genetic properties. [ Method ] Genetic effects of seed coat cha...[ Objective] This study is to provide basis for the genetic improvement of triploid watermelon cultivars from seed coat characteristiscs by analyzing its genetic properties. [ Method ] Genetic effects of seed coat characteristics and their related characteristics in tdploid watermelon were analyzed by additive dominant genetic model based on 36 F1 hybrids which were crossed by six female parents of four ecotypes and six male parents of same ecotype according to North Carolina II crossing design. [ Result] The seed coat number characteristics was controlled by additive effects, dominant effects and error variance of genetic together. The additive effects of the length and width of abortive seed coat were significant, and the error variance was significant or highly significant. It was observed that there was a significant negative correlation of additive effects between the seed coat number and fringe soluble sugar. Also there was a significant negative correlation of dominant effects between lycopenes, dry matter and the seed coat number. However, there was a highly significant positive correlation in additive effects between the length and width of abortive seed coat. [ Conclusion ] The results provide guidance for genetic breeding of triploid watermelon cultivars.展开更多
The concept of the coherence function is adopted to find the wind pressure correlation of two points on domes of different rise-span ratios. The pressure measurements are made on the dome roof models by the wind tunne...The concept of the coherence function is adopted to find the wind pressure correlation of two points on domes of different rise-span ratios. The pressure measurements are made on the dome roof models by the wind tunnel test. The coherence functions for different separation distances at several directions of the domes from different wind directions are examined. The results show that there is a strong correlation for two adjacent points at low frequency, but not for non-adjacent points. The coherence of the wind pressure increases with the decrease in the separation distance. Moreover, the coherence of the wind pressure is in the strongest correlation on the along-wind direction at the same separation, but the lowest correlation is on the cross-wind direction. The detailed derivation of the proposed exponential coherence model of the wind pressure from experimental data is also discussed. It is found that the proposed exponential coherence model can be appropriate, especially, for small separations and the change in the directions on domes. Based on the quasi-steady theory, the relationship between the wind pressure and the wind velocity on the basis of the coherence model is also examined. The coherence observed between the wind pressure and the wind velocity is not adequately predicted by the quasi-steady theory.展开更多
Objective Rheumatoid arthritis(RA)is an autoimmune disease involving the synovial lining of the major joints.Current therapies have noteworthy side effects.Our study involved in silico evaluation of Ehretia laevis(E.l...Objective Rheumatoid arthritis(RA)is an autoimmune disease involving the synovial lining of the major joints.Current therapies have noteworthy side effects.Our study involved in silico evaluation of Ehretia laevis(E.laevis)phytoconstituents targeting tumor necrosis factor-α(TNF-α).Methods Molecular docking studies performed to investigate the binding pattern of the plant E.laevis phytoconstituents along with the crystal structure of TNF-α(PDB ID:2 AZ5)using AutoDock Vina followed by a study of interacting amino acid residues and their influence on the inhibitory potentials of the active constituents.Further the pharmacokinetic profile and toxicity screening carried out using Swiss ADME and pk CSM.Results The docked results suggest that lupeol(-9.4 kcal/mol)andα-amyrin(-9.4 kcal/mol)has best affinity towards TNF-αcompared to standard drug thalidomide(-7.4 kcal/mol).The active chemical constituents represents better interaction with the conserved catalytic residues,leading to the inhibition/blockade of the TNF-α-associated signaling pathway in RA.Furthermore,pharmacokinetics and toxicity parameters of these phytochemicals were within acceptable limits according to ADMET studies.Conclusion The binding potential of phytoconstituents targeting TNF-αshowed promising results.Nonetheless,it encourages the traditional use of E.laevis and provides vital information on drug development and clinical treatment.展开更多
including octupole correlations in the Nilsson potential,the ground-state rotational bands in the reflection-asymmetric(RA)nuclei are investigated by using the cranked shell model(CSM)with the monopole and quadrupole ...including octupole correlations in the Nilsson potential,the ground-state rotational bands in the reflection-asymmetric(RA)nuclei are investigated by using the cranked shell model(CSM)with the monopole and quadrupole pairing correlations treated by a particle-number-conserving(PNC)method.The experimental kinematic moments ofinertia(Mols)for alternating-parity bands in the even-even nuclei ^(236,238)U and ^(238,240)Pu,as well as paritydoublet bands in the odd-A nuclei 237U and 239Pu are reproduced well by the PNC-CSM calculations.The higher J(1)for the intrinsic s=-i bands in ^(237)U and ^(239)Pu,compared with the s=+1 bands in the neighboring even-even nuclei ^(236,238)U and ^(238,240)Pu,can be attributed to the pairing gap reduction due to the Pauli blocking effect.The gradual increase of J(i)versus rotational frequency can be explained by the pairing gap reduction due to the rotation.The Mols of reflection-asymmetric nuclei are higher than those of reflection-symmetric(RS)nuclei at low rotational frequency.Moreover,the inclusion of a larger octupole deformation 8,in the RA nuclei results in more significant pairing gap reduction compared with the RS nuclei.展开更多
The sponge-associated fungus Nectria sp.HLS206,which belongs to the order of Hypocreales,was isolated from the marine sponge Gelliodes carnosa collected from the South China Sea.The secondary metabolites of the fungus...The sponge-associated fungus Nectria sp.HLS206,which belongs to the order of Hypocreales,was isolated from the marine sponge Gelliodes carnosa collected from the South China Sea.The secondary metabolites of the fungus were isolated.From the solid cultures,five compounds were purified,which are chalmicrin(1),hypocrealesate(2),fucosterol(3),stigmasterol(4) and β-sitosterol(5).The structures of the 5 compounds were elucidated by ESI-MS,1D and 2D NMR spectra(COSY,HMQC and HMBC).To the best of our knowledge,it is the first time compound 1 was isolated from the order of Hypocreales,and the spectral data of compound 2 are also firstly reported.展开更多
Nonlinear vibration with axisymmetric 3:1 internal resonance is investigated for an incompressible neo-Hookean hyperelastic cylindrical shell under both axial and radial harmonic excitations.A full nonlinear strain-di...Nonlinear vibration with axisymmetric 3:1 internal resonance is investigated for an incompressible neo-Hookean hyperelastic cylindrical shell under both axial and radial harmonic excitations.A full nonlinear strain-displacement relation is derived from the large deflection theory of thin-walled shells.A set of nonlinear differential equations describing the large deflection vibration are formulated by the Lagrange equation and the assumption of small strains.Steady-state responses of the system are predicted via the harmonic balance method with the arc length continuation,and their stabilities are determined via the modified sorting method.The effects of excitations on the steady-state responses are analyzed.The results reveal a crucial role played by the phase difference in the structural response,and the phase difference can effectively control the amplitude of vibration.展开更多
文摘[ Objective] This study is to provide basis for the genetic improvement of triploid watermelon cultivars from seed coat characteristiscs by analyzing its genetic properties. [ Method ] Genetic effects of seed coat characteristics and their related characteristics in tdploid watermelon were analyzed by additive dominant genetic model based on 36 F1 hybrids which were crossed by six female parents of four ecotypes and six male parents of same ecotype according to North Carolina II crossing design. [ Result] The seed coat number characteristics was controlled by additive effects, dominant effects and error variance of genetic together. The additive effects of the length and width of abortive seed coat were significant, and the error variance was significant or highly significant. It was observed that there was a significant negative correlation of additive effects between the seed coat number and fringe soluble sugar. Also there was a significant negative correlation of dominant effects between lycopenes, dry matter and the seed coat number. However, there was a highly significant positive correlation in additive effects between the length and width of abortive seed coat. [ Conclusion ] The results provide guidance for genetic breeding of triploid watermelon cultivars.
基金The National Natural Science Foundation of China (No.50678036)
文摘The concept of the coherence function is adopted to find the wind pressure correlation of two points on domes of different rise-span ratios. The pressure measurements are made on the dome roof models by the wind tunnel test. The coherence functions for different separation distances at several directions of the domes from different wind directions are examined. The results show that there is a strong correlation for two adjacent points at low frequency, but not for non-adjacent points. The coherence of the wind pressure increases with the decrease in the separation distance. Moreover, the coherence of the wind pressure is in the strongest correlation on the along-wind direction at the same separation, but the lowest correlation is on the cross-wind direction. The detailed derivation of the proposed exponential coherence model of the wind pressure from experimental data is also discussed. It is found that the proposed exponential coherence model can be appropriate, especially, for small separations and the change in the directions on domes. Based on the quasi-steady theory, the relationship between the wind pressure and the wind velocity on the basis of the coherence model is also examined. The coherence observed between the wind pressure and the wind velocity is not adequately predicted by the quasi-steady theory.
文摘Objective Rheumatoid arthritis(RA)is an autoimmune disease involving the synovial lining of the major joints.Current therapies have noteworthy side effects.Our study involved in silico evaluation of Ehretia laevis(E.laevis)phytoconstituents targeting tumor necrosis factor-α(TNF-α).Methods Molecular docking studies performed to investigate the binding pattern of the plant E.laevis phytoconstituents along with the crystal structure of TNF-α(PDB ID:2 AZ5)using AutoDock Vina followed by a study of interacting amino acid residues and their influence on the inhibitory potentials of the active constituents.Further the pharmacokinetic profile and toxicity screening carried out using Swiss ADME and pk CSM.Results The docked results suggest that lupeol(-9.4 kcal/mol)andα-amyrin(-9.4 kcal/mol)has best affinity towards TNF-αcompared to standard drug thalidomide(-7.4 kcal/mol).The active chemical constituents represents better interaction with the conserved catalytic residues,leading to the inhibition/blockade of the TNF-α-associated signaling pathway in RA.Furthermore,pharmacokinetics and toxicity parameters of these phytochemicals were within acceptable limits according to ADMET studies.Conclusion The binding potential of phytoconstituents targeting TNF-αshowed promising results.Nonetheless,it encourages the traditional use of E.laevis and provides vital information on drug development and clinical treatment.
文摘including octupole correlations in the Nilsson potential,the ground-state rotational bands in the reflection-asymmetric(RA)nuclei are investigated by using the cranked shell model(CSM)with the monopole and quadrupole pairing correlations treated by a particle-number-conserving(PNC)method.The experimental kinematic moments ofinertia(Mols)for alternating-parity bands in the even-even nuclei ^(236,238)U and ^(238,240)Pu,as well as paritydoublet bands in the odd-A nuclei 237U and 239Pu are reproduced well by the PNC-CSM calculations.The higher J(1)for the intrinsic s=-i bands in ^(237)U and ^(239)Pu,compared with the s=+1 bands in the neighboring even-even nuclei ^(236,238)U and ^(238,240)Pu,can be attributed to the pairing gap reduction due to the Pauli blocking effect.The gradual increase of J(i)versus rotational frequency can be explained by the pairing gap reduction due to the rotation.The Mols of reflection-asymmetric nuclei are higher than those of reflection-symmetric(RS)nuclei at low rotational frequency.Moreover,the inclusion of a larger octupole deformation 8,in the RA nuclei results in more significant pairing gap reduction compared with the RS nuclei.
基金National Science and Technology Project of China(Grant No.2009ZX09301-003-4-1)
文摘The sponge-associated fungus Nectria sp.HLS206,which belongs to the order of Hypocreales,was isolated from the marine sponge Gelliodes carnosa collected from the South China Sea.The secondary metabolites of the fungus were isolated.From the solid cultures,five compounds were purified,which are chalmicrin(1),hypocrealesate(2),fucosterol(3),stigmasterol(4) and β-sitosterol(5).The structures of the 5 compounds were elucidated by ESI-MS,1D and 2D NMR spectra(COSY,HMQC and HMBC).To the best of our knowledge,it is the first time compound 1 was isolated from the order of Hypocreales,and the spectral data of compound 2 are also firstly reported.
基金This work was supported by the National Natural Science Foundation of China(Grant Nos.11672069,11872145,11872159,12172086,and 12101106).
文摘Nonlinear vibration with axisymmetric 3:1 internal resonance is investigated for an incompressible neo-Hookean hyperelastic cylindrical shell under both axial and radial harmonic excitations.A full nonlinear strain-displacement relation is derived from the large deflection theory of thin-walled shells.A set of nonlinear differential equations describing the large deflection vibration are formulated by the Lagrange equation and the assumption of small strains.Steady-state responses of the system are predicted via the harmonic balance method with the arc length continuation,and their stabilities are determined via the modified sorting method.The effects of excitations on the steady-state responses are analyzed.The results reveal a crucial role played by the phase difference in the structural response,and the phase difference can effectively control the amplitude of vibration.