雷公藤合剂配合手关节操治疗活动期类风湿关节炎临床研究

目的:探讨在雷公藤合剂配合手关节操治疗活动期类风湿关节炎的疗效。方法:按疾病活动度分层随机对照将60例合格受试者以1:1的比例分配到治疗组30例,对照组30例。治疗组:予雷公藤合剂(雷公藤、白芍、甘草)+手关节操+甲氨蝶呤+来氟米特。对照组:予甲氨蝶呤+来氟米特。观察12周。检测指标:治疗前、治疗后4周、8周、12周分别记录指关节压痛数(TJC)、指关节肿胀数(SJC)、血沉(ESR)、C反应蛋白(CRP)及患者对疾病的自我总体评分(GH)、疾病活动度评估(DAS 28评分)。结果:1治疗前两组比较,均P>0.05,无显著差异,具有可比性;2治疗组在治疗后4周、8周、12周分别与治疗前比较,均P<0.05,均有显著性差异;对照组ESR、CRP在治疗后4周与治疗前比较,P>0.05,无显著差异,在治疗后8周、12周与治疗前分别比较,P<0.05,具有显著性差异,说明在改善炎性指标方面,治疗组优于对照组;对照组TJC、SJC、DAS28治疗后4周、8周、12周与治疗前分别比较,P<0.05,均有显著性差异;3炎性指标ESR、CRP分别在治疗后4周、8周、12周进行两组间比较,P<0.05,两组间均有差异;DAS28、GH在治疗后12周两组间比较有差异,P<0.05。TJC、SJC在治疗后4周、8周、12周进行两组间比较,均P>0.05,两组间无差异;4不良反应统计学无差异。结论:雷公藤合剂联合手关节操治疗湿热痹阻型类风湿关节炎在改善炎性指标方面起效快,改善程度优于对照组;治疗12周后患者对疾病的自我总体评分优于对照组,满意度高;DAS28亦提示在治疗后12周治疗组优于对照组。

关手我们的一切

当我一遍又一遍的看着《亮剑》那感人的剧情时，便想起了我们之间的一切。至于编制嘛，记得周胖说过一句话：“咱可不兴这个。”这很好，用得着吗，我们这帮懒人最怕麻烦。

类风湿性关节炎膝关节病变的X线影像学研究

目的 :分析类风湿性关节炎(RA)膝关节病变的X线影像学特征,以提高诊断正确率。方法 :收集2015年2月至2017年2月收治的RA患者52例和骨关节炎患者45例,进行X线摄片,分析两组膝关节病变的影像学特征。结果 :RA组中,关节间隙呈均匀性狭窄47例(90.4%),髌上囊肿胀41例(78.8%),关节面毛糙、关节面不同程度侵蚀破坏22例,关节周缘轻度骨质增生43例,明显重度增生、骨赘形成5例,未见明显骨质增生4例,52例均有不同程度骨质疏松。OA组中,关节间隙呈均匀性狭窄5例(11.1%),髌上囊肿胀16例(35.6%),关节面下小囊性改变7例,45例有不同程度骨质增生、骨赘形成改变。两组关节间隙均匀狭窄及髌上囊肿胀改变发生率差异有统计学意义(P<0.05)。结论 :RA膝关节病变的X线影像学表现具有一定特征性,尤其是关节间隙均匀性狭窄、髌上囊肿胀及关节面侵蚀的改变在鉴别RA和OA的诊断中有重要价值。

Inverse kinematic optimal design of 6-DOF parallel manipulators

To obtain the required articular velocities as lower as possible for the given kinematics of the moving platform, this paper focuses on this kind of articular velocities optimization of 6-DOF parallel manipulators. Based on the inverse kinematic analysis, the H∞ norm of the weighted Jacobian matrix was adopted as the performance index to minimize the articular velocities, and then the optimal design problem was formulated to find a manipulator geometry that minimized the global performance index with the constraints of the workspace and structural parameters limits. Since the optimal design problem is a constrained nonlinear optimization problem without explicit analytical expressions, the genetic algorithm was applied to numerically solve the problem. Simulation results indicate that the articular velocities of the optimal manipulators can be the minimum while the kinematic reauirements of the moving platform are satisfied.

Study of the relationship between acupuncture dose and effect

Acupuncture dose-effect relationship is the essential feature of acupuncture and the key factor of acupuncture’s therapeutic effect.It is a comprehensive category,including needle direction,needle strength,needle depth,selection of specific techniques,length of time between acupuncture treatment sessions,length of needle retention time,and frequency of treatment,all of which play a decisive role in the curative effect and prognosis of diseases[1].

Use of Cataract Surgery in Urban Beijing: a Post Screening Follow-up of the Elderly with Visual Impairment due to Age-related Cataract

Objective To understand the perception for the use of cataract surgical services in a population acceptors and non-acceptors of cataract surgery in urban Beijing. Methods From a community-based screening program a total of 158 patients with presenting visual acuity of less than 6/18 on either eye due to age-related cataract were informed about the possibility of surgical treatment. These patients were interviewed and re-examined 36 to 46 months after initial screening. The main reasons for not accepting surgery were obtained using a questionnaire. Vision function and vision-related quality of life scores were assessed in those who received and did not receive surgery. Results At the follow-up examination 116 of the 158 patients were available and 36 （31.0%） had undergone cataract surgery. Cases who chose surgery had higher education level than those who did not seek surgery （OR=2.64, 95% CI： 1.08-6.63, P=0.02）. There were no significant differences in vision function （P=0.11） or quality of life scores （P=0.16） between the surgery group and the non-surgery group. Main reasons for not having surgery included no perceived need （50.0%）, feeling of being ＂too old＂ （19.2%）, and worry about the quality of surgery （9.6%）. Cost was seeking surgery. cited by 1 （1.9%） subject as the main reason for not

Drainage does not Promote Post-operative Rehabilitation After Bilateral Total Knee Arthroplasties Compared With Nondrainage

Objective To assess the effects of suction drainage versus nondrainage on the post-operative rehabilitation of patients receiving primary bilateral total knee arthroplasties(TKA).Methods A prospective study including 40 patients was conducted.These patients were diagnosed with osteoarthritis and underwent primary bilateral TKA between October 2007 and September 2009 with the same operation team.A suction drainage was placed by randomization in only one knee for each patient,while the other knee as self-control.Pain visual analogue scale score,extremity swelling,wound healing,range of motion and incidence of early post-operative complications between the drained and nondrained group were compared statistically.Results Each patient was followed up for 12 months.Placing drainage did not relieve the pain,extremity swelling,ecchymosis,or reduce the incidence of early complications(all P>0.05).Conclusions Suction drainage in TKA does not exhibit substantial advantages in promoting post-operative rehabilitation after unsophisticated TKA,compared with nondrainage.On the other hand,it might complicate the surgical operation,and increase the incidence of post-operative hemorrhage and retrograde infection.Thus we do not recommend suction drainage in unsophisticated TKA.

Analysis of Puns in English Advertising Language From the Relevance Theory

The pun becomes the most popular language strategy for advertisers as a broadly used rhetorical device. Using pun words felicitously not only makes advertising language more humorous, implicative, and vivid but also leaves the audience a room to imagine and enjoy. The author summarizes pun＇s definitions, features, classifications, and how the pun procures a successful communicative activity in English advertisements based on Sperber and Wilson＇s Relevance Theory. At last, the pun＇s pragmatic functions are concluded.

王富春针刺手三关穴治疗神经根型颈椎病手指麻木经验

介绍王富春教授运用手三关穴治疗神经根型颈椎病手指麻木症状的临床经验。王教授认为脾阳不足,湿邪困阻中焦脾土,水谷精微无以送至四肢经络,加之风寒湿外邪或痰湿、瘀血阻滞,久之则经络气血阻滞,而发手指麻木之症。临床上治当循因结合辨经治疗,选取手三阳经循行部位的穴位和腕背横纹三穴,同时选取神经根型颈椎病的主穴,结合效验穴手三关穴,以理气活血、通络止痛,扶正兼驱邪外出,临床效果显著。并附验案1则,加以佐证。

Exploring relations between city regions based on mobile phone data

City regions often have great diversity in form and function. To better understand the role of each region, the relations between city regions need to be carefully studied. In this work, the human mobility relations between regions of Shanghai based on mobile phone data is explored. By formulating the regions as nodes in a network and the commuting between each pair of regions as link weights, the distribution of nodes degree, and spatial structures of communities in this relation network are studied. Statistics show that regions locate in urban centers and traffic hubs have significantly larger degrees. Moreover, two kinds of spatial structures of communities are found. In most communities, nodes are spatially neighboring. However, in the communities that cover traffic hubs, nodes often locate along corridors.

Fingerspelling Recognition by Hand Shape Using Higher-Order Local Auto-Correlation Features

The fingerspelling recognition by hand shape is an important step for developing a human-computer interaction system. A method of fingerspelling recognition by hand shape using HLAC （higher-order local auto-correlation） features is proposed. Furthermore, in order to use HLAC features more effectively, the use of image processing techniques： reducing an image resolution, dividing an image, and image pre-processing techniques, is also proposed. The experimental results show that the proposed method is promising.

Molecular Markers Associated with Starch Content and Implications for Sugarcane Introgression Breeding Using Saccharum spontaneum

Introgression with Saceharum spontaneum intended to broaden the genetic base of sugarcane resulted in an increase in desirable genes for broader adapt ability as well as undesirable genes for high starch content. Markers could provide a quick and efficient method of screening parental genotypes for low starch. The objectives of this study were to identify potential markers associated with starch in S. spontaneum population and evaluate their potential for screening for starch content. Data for starch content and （simple sequence repeats） SSR markers were collected from 51 S. spontaneum clones grown in replicated pots. The mixed procedure of statistical analysis system （SAS） was used to determine markers significantly associated with starch. Thirty-nine out of 357 polymorphic markers were significantly （P 〈 0.05） associated with starch content. Eighteen were positively associated and 21 were negatively associated. The presence of a positive marker produced 39% more starch than absence while the absence of a negative marker produced 57% more starch than presence. Selecting parents using negative markers may be more efficient than selecting using positive markers.

“Tong Guan Li Qiao” Acupuncture Therapy on Post-Stroke Dysphagia

The differences between the“Tong Guan Li Qiao”acupuncture therapy and the conventional and current other acupuncture methods for poststroke dysphagia are as follows:first,it adheres to the basic idea of "Xing Nao Kai Qiao"acupuncture therapy in selecting and combining acupoints,centers on the brain,and combines the dysphagia symptoms of the mouth,tongue,and throat-related orifices with the root cause of"brain";second,thereare strictand standard requirements intheacupuncture operation,that is,manipulation quantification.In addition to standardized twirling,lifting,and thrusting,the techniques of deep needling on the acupoints in the neck region,blood-letting puncturing at the posterior wallof the pharynx,and theneedling sensation of"like a fishbone getting stuck in the throat"are all unique.

Chiral Magnetic Effect and Chiral Phase Transition

We study the influence of the chiral phase transition on the chiral magnetic effect. The azimuthal charge-particle correlations as functions of the temperature are calculated. It is found that there is a pronounced cusp in the correlations as the temperature reaches its critical value for the QCD phase transition. It is predicted that there will be a drastic suppression of the charge-particle correlations as the collision energy in RHIC decreases to below a critical value. We show then the azimuthal charge-particle correlations can be the signal to identify the occurrence of the QCD phase transitions in RHIC energy scan experiments.

Analysis of Shock Acceleration by Dotting of Finger Braille and Influence of Postures of Receiver＇s Hand

Finger Braille is one of the tactual communication media of deafblind people. In one-handed Finger Braille, a sender dots the left part of the Braille code on the Distal Interphalangeal （DIP） joints of the index, middle and ring fingers of a receiver, and subsequently dots the right part of the Braille code on the Proximal Interphalangeal （PIP）joints of the same fingers. Because there is a small number of non-disabled people who are skilled in Finger Braille, deafblind people communicate in this medium only through an interpreter. We have been developing a Finger Braille recognition system using small piezoelectric accelerometers worn by the receiver To recognize the dotted positions （DIP or PIP joints）, we have made a hypothesis that the dotting on the DIP joints causes a hard impact, and the dotting on the PIP joints causes a soft impact, when the receiver＇s hand forms a natural longitudinal arch on the desk. The difference of each impact is indicated by its damping amplitude ratio. In this paper, a measurement experiment about the postures of the receiver＇s hand was conducted. The postures of the receiver＇s hand were as follows： forming the natural longitudinal arch on the desk and fully contacting the desk. As a result, the dotting on the DIP joints of both postures caused the hard impacts; the dotting on the PIP joints caused the soft impact when the receiver＇s hand formed the natural longitudinal arch; the dotting on the PIP joints caused the hard impact when the receiver＇s hand fully contacted the desk. Therefore, we could verify the hypothesis.

Investigations on Left Hand Cut Contribution to Determination of κ（700） Pole

The uncertainties of background contributions to J = 0 partial wave πK scattering phase shifts are carefully studied. We firstly point out that the circular cuts exhibit different characters in S1/1 and S3/2 waves. While the former contributes negatively to the scattering length parameter, the latter contributes positively, i.e., has a wrong sign. This fact indicates that short range force contribu tions to the phase shift are non-negligible in the exotic channel. Nevertheless, it is verified that the κ pole will be affected only slightly with respect to the theoretical uncertainty in estimating the left hand cut contributions.

Cutting Techniques for Facilities Dismantling in Decommissioning Projects

Fuel cycle related activities were accomplished in IPEN-CNEN/SP in laboratory and pilot plant scale and most facilities were built in the 70-80 years. Nevertheless, radical changes of the Brazilian nuclear policy in the beginning of 90＇s determined the interruption of several fuel cycle activities and facilities shutdown. Some laboratory and pilot plant decommissioning activities have been performed in IPEN in the last years. During the operational activities in the decommissioning of old nuclear fuel cycle facilities, the personnel involved in the task had to face several problems. In old facilities, the need of large components dismantling and material removal use to present some difficulties, such as lack of available and near electricity supply. Besides this, the spread out of the superficial contamination in the form of dust or aerosols and the exposure of workers should be as much as possible avoided. Then, the selection and availability of suitable tools for the task, mainly those employed for cutting and segmentation of different materials is of significant importance. Slight hand tools, mainly those powered by rechargeable batteries, facilitate the work, especially in areas where the access is difficult. Based on the experience in the dismantling of some old nuclear facilities of IPEN-CNEN/SP, some tools that would have facilitated the operations were identified and their availability could have improved the quality and efficiency of different individual tasks. In this paper, different cutting problems and techniques, as well as some available commercial hand tools, are presented as suggestion for future activities.

Equation of State of Nuclear Matter in Chiral σ-ω Model

The equation of state of nuclear matter is studied in the 1-loop approximation of chiral linear σ-ω model.By introducing the density-dependent coupling constants, the problem of tachyon pole in the chiral σ-ω model is resolved.The 1-loop contributions ofσ and π mesons to the nucleon's binding energy are included, while the empirical properties of nuclear matter such as saturation density, binding energy, and incompressibility are well reproduced.

TSS （Tourism Support System） as a New Competitive Tourism Marketing Instrument

The recent trend in tourism marketing is focus on customer relationship management. Tourism industry today is one of the highest revenue generating industry and strategic approach for sustainable development of this industry hosts benefits not only for the tourism related stakeholders but also the community and economy on the whole. Oman is one of the most preferred destinations for the tourists especially after the declaration of Muscat, Arab tourism Capital for 2012. Thus to materialize this honor and position, the scientific study and analysis of tourist behavior will help to predict the future trend of tourism and will give direction for effort investment. This work presents a novel strategy to identify, analyze and highlights the main tourist behavioral factors that could increase tourists＇ loyalty to a specific destination or agency. The analytical TSS （tourism support system） will also classify customers into two categories--first category will be classified as ＂LT （loyal tourists）＂ and second category as ＂NLT （non-loyal tourists）＂. Dataset is collected from a tourism business organization. Twenty-four attributes and 545 instances were collected and were analyzed by algorithms like logistics, forest of random trees, naive Bayes, J48 and Id3. The explanatory variables were defined, and some transformations were done to identify the response variable. Entropy was used and adapted in order to find the response variable from the explanatory variables. The results obtained from this work confirm that the generated rules can be used for future prediction and tourism business can be improved and efforts can be directed in right place for the right consumer resulting in high return on investment.

编辑手记

本册的关注焦点聚焦于风景园林学专业的教学改革与实践。风景园林学科被国家确立为建筑领域的一级学科,有效地完善了以往建筑相关学科对于城市景观的忽视之处。但在其上升为一级学科的三年时间里,国内各高校莫不在探索一条学科发展之路,始终缺乏对于学科升级以来的教育改革与实践的系统性的探讨,因此,本册《中国建筑教育》在组稿之初,特别选择风景园林学科改革较早的院校之一——哈尔滨工业大学建筑学院风景园林系,历经半年多时间与前后两位系主任沟通合作,希望通过对该校近年来关手风景园林学科教学理念、理论依据与实际操作过程的变革等方面进行较为全面的探讨。