In this paper,the dynamical evolutions of two types of Arctic Oscillation (AO),the stratospheric (S) and tropospheric (T) types,have been investigated on an intermediate time scale in terms of transient eddy feedback ...In this paper,the dynamical evolutions of two types of Arctic Oscillation (AO),the stratospheric (S) and tropospheric (T) types,have been investigated on an intermediate time scale in terms of transient eddy feedback forcing and three-dimensional Rossby wave propagation.S-Type (T-type) events are characterized by an anomalous stratospheric polar vortex that is in phase (out of phase) with its tropospheric counterpart.Approximately onethird of AO events,both positive and negative,are T-type events.For the positive phase of a T-type event,the formation and maintenance of stratospheric positive anomalies over the polar cap are associated with an upward propagation of Rossby wave packets originating from the near-tropopause altitude over northeastern Asia.However,such upward propagating features are not found for S-type events.In the troposphere,transient eddy feedback forcing is primarily responsible for the meridional seesaw structure of both the S-and T-type events,with an additional contribution from Rossby wave propagation.展开更多
Objective We investigated the correlation between the expression of the sodium-iodide symporter(NIS) and the detection of circulating tumor cells(CTCs) in differentiated thyroid carcinoma(DTC).Methods NIS expression i...Objective We investigated the correlation between the expression of the sodium-iodide symporter(NIS) and the detection of circulating tumor cells(CTCs) in differentiated thyroid carcinoma(DTC).Methods NIS expression in differentiated thyroid and the positive rate of CTCs in the peripheral blood were determined by immunohistochemistry S-P and flow cytometry from the records of 172 cases of differentiated thyroid carcinoma.Results Seventy-six cases(44.2%) expressed NIS in the differentiated thyroid and 63 cases(36.6%) were positive for CTCs in the peripheral blood. There was a significant difference between N0 and N1 in the expression of NIS(χ~2 = 6.015, P = 0.014) and the positive rate of CTCs(χ~2 = 14.035, P = 0.001). N0 and N1 also differed significantly in the expression of NIS(r =-0.383,-0.610, P = 0.002, < 0.001). The differences in the NIS expression, but not in the positive rate of CTCs, were significant among the different pathological subtypes(χ~2 = 7.897, P = 0.005; χ~2 = 1.455, P = 0.228, respectively). There was a significant negative correlation between the highly differentiated type and intermediate differentiation type both in the expression of NIS and positive rate of CTCs(r =-0.591,-0.443, P < 0.001, P = 0.002). Conclusion There was a significant negative correlation between the expression of tissue NIS and positive rate of CTCs in the peripheral blood in DTC. The malignancy level and lymph node metastasis in differentiated thyroid carcinoma were negatively correlated with NIS expression and positively correlated with the positive rate of CTC.展开更多
基金supported by the National Basic Research Program of China (973 Program) under Grant 2009CB421406the National Key Technologies R & D Programof China under Grant 2009BAC51B02
文摘In this paper,the dynamical evolutions of two types of Arctic Oscillation (AO),the stratospheric (S) and tropospheric (T) types,have been investigated on an intermediate time scale in terms of transient eddy feedback forcing and three-dimensional Rossby wave propagation.S-Type (T-type) events are characterized by an anomalous stratospheric polar vortex that is in phase (out of phase) with its tropospheric counterpart.Approximately onethird of AO events,both positive and negative,are T-type events.For the positive phase of a T-type event,the formation and maintenance of stratospheric positive anomalies over the polar cap are associated with an upward propagation of Rossby wave packets originating from the near-tropopause altitude over northeastern Asia.However,such upward propagating features are not found for S-type events.In the troposphere,transient eddy feedback forcing is primarily responsible for the meridional seesaw structure of both the S-and T-type events,with an additional contribution from Rossby wave propagation.
基金Supported by a grant from the Gansu Province Key Traditional Chinese Medicine Project(No.GZK-2010-Z9)
文摘Objective We investigated the correlation between the expression of the sodium-iodide symporter(NIS) and the detection of circulating tumor cells(CTCs) in differentiated thyroid carcinoma(DTC).Methods NIS expression in differentiated thyroid and the positive rate of CTCs in the peripheral blood were determined by immunohistochemistry S-P and flow cytometry from the records of 172 cases of differentiated thyroid carcinoma.Results Seventy-six cases(44.2%) expressed NIS in the differentiated thyroid and 63 cases(36.6%) were positive for CTCs in the peripheral blood. There was a significant difference between N0 and N1 in the expression of NIS(χ~2 = 6.015, P = 0.014) and the positive rate of CTCs(χ~2 = 14.035, P = 0.001). N0 and N1 also differed significantly in the expression of NIS(r =-0.383,-0.610, P = 0.002, < 0.001). The differences in the NIS expression, but not in the positive rate of CTCs, were significant among the different pathological subtypes(χ~2 = 7.897, P = 0.005; χ~2 = 1.455, P = 0.228, respectively). There was a significant negative correlation between the highly differentiated type and intermediate differentiation type both in the expression of NIS and positive rate of CTCs(r =-0.591,-0.443, P < 0.001, P = 0.002). Conclusion There was a significant negative correlation between the expression of tissue NIS and positive rate of CTCs in the peripheral blood in DTC. The malignancy level and lymph node metastasis in differentiated thyroid carcinoma were negatively correlated with NIS expression and positively correlated with the positive rate of CTC.
