Objective: To examine the changes of mu-opioid receptors (MORs) expression in human chronic inflamed knee joint synovium tissue. Methods:Knee joint synovium tissues were taken from 21 patients with chronic arthritis (...Objective: To examine the changes of mu-opioid receptors (MORs) expression in human chronic inflamed knee joint synovium tissue. Methods:Knee joint synovium tissues were taken from 21 patients with chronic arthritis (inflamed group) and 6 fresh bodies with normal knee joints (control group). And the expression of MORs was detected by using immunohistochemistry. flow cytometry(FCM) and reverse-transcription polymerase chain reaction (RT-PCR). Results: The expression of MORs in the inflamed group was significantly higher than that in the normal group by using the 3 techniques(P<0. 05). Conclusion: Chronic inflammation enhances the up-regulation of MORs in human knee joint synovium tissue.展开更多
Objective: To observe the clinical effect of warm needling moxibustion plus acupoint sticking therapy for cervical radiculopathy. Methods: A total of 120 cases were allocated into an observation group, a warm needling...Objective: To observe the clinical effect of warm needling moxibustion plus acupoint sticking therapy for cervical radiculopathy. Methods: A total of 120 cases were allocated into an observation group, a warm needling group and an acupoint sticking group according to the random number table, with 40 cases in each group. Cases in the observation group received warm needling moxibustion plus acupoint sticking therapy;cases in the warm needling group received the same warm needling moxibustion in the observation group;cases in the acupoint sticking group received the same acupoint sticking therapy in the observation group. The scores of Japanese Orthopaedic Association (JOA) and visual analog scale (VAS) were recorded before and after treatment. Results: The total effective rate was 95.0% in the observation group, versus 77.5% in the warm needling group and 75.0% in the acupoint sticking group (both P<0.05). Inter-group differences in JOA and VAS between the observation group and the other two groups were statistically significant (all P<0.05). Conclusion: Warm needling moxibustion plus acupoint sticking therapy is effective in treating cervical radiculopathy, and it can significantly alleviate pain and enhance clinical efficacy, and thus is worth clinical popularization.展开更多
Objective:To observe the clinical effect of Zheng's Jin Gou Diao Yu(gold-hook-fishing)acupuncture method versus ordinary acupuncture on superficial fascia for treating neck type cervical spondylopathy in Kyrgyz.Me...Objective:To observe the clinical effect of Zheng's Jin Gou Diao Yu(gold-hook-fishing)acupuncture method versus ordinary acupuncture on superficial fascia for treating neck type cervical spondylopathy in Kyrgyz.Methods:A total of 64 Kyrgyz patients conforming to the diagnostic criteria of neck type cervical spondylopathy were included.The patients were randomized into a Zheng's Jin Gou Diao Yu(gold-hook-fishing)acupuncture group and a conventional acupuncture group,with 32 cases in each group.Patients in the Zheng's Jin Gou Diao Yu(gold-hook-fishing)acupuncture group were treated with Zheng's Jin Gou Diao Yu(gold-hook-fishing)acupuncture method to stimulate the superficial fascia,the stimulation sites were primarily located at bilateral sides of the cervical vertebra as well as the trigger points in shoulder-neck region;patients in the conventional acupuncture group were punctured at the same acupoints,with twirling reducing method,and the depth of insertion was determined by the treated region.Patients in both groups received treatment every day for a succession of 5 d as a course,with a 2-day interval between 2 courses,and the whole treatment lasted for 3 courses.After 3 courses of treatment,the McGill pain questionnaire(MPQ)and neck disability index(NDI)were measured to compare the clinical effect between the two groups.Results:After treatment,scores of MPQ and NDI scale dropped when compared with those before treatment,and the differences showed statistical significance(all P<0.05);scores of MPQ and NDI in the Jin Gou Diao Yu(gold-hook-fishing)acupuncture group were substantially lower than those in the conventional acupuncture group,and the differences showed statistical significance(all P<0.05).The total effective rate was 96.9%in the Jin Gou Diao Yu(gold-hook-fishing)acupuncture group and the cured rate was 78.1%,which were higher than 81.3%and 40.6%in the conventional acupuncture group,and the differences showed statistical significance(both P<0.05).Conclusion:Zheng's Jin Gou Diao Yu(gold-hook-fishing)acupuncture method by stimulating superficial fascia to treat cervical spondylopathy in Kyrgyz can produce a better clinical effect than conventional acupuncture treatment,and is effective in improving pain and stiffness in patients,and thus is worth clinical popularization.展开更多
Objective： To observe the efficacy and safety of bloodletting and cupping for cervical radiculopathy. Methods： The randomized controlled clinical trial was conducted in five centers. A total of 183 eligible subjects...Objective： To observe the efficacy and safety of bloodletting and cupping for cervical radiculopathy. Methods： The randomized controlled clinical trial was conducted in five centers. A total of 183 eligible subjects were randomly allocated into a bloodletting group （n=68）, an acupuncture group （n=56） and a combined group （n=59）. Patients in the bloodletting group were treated with bloodletting at Dazhui （GV 14） and Jianjing （GB 21） on the affected side, coupled with 5-10 min of cupping, 5 mL blood for each cup, 2-3 cups for one treatment. Patients in the acupuncture group were treated with needling cervical Jiaji （EX-B 2） points and Jianjing （GB 21） on the affected side. The needles were retained for 30 min. Patients in the combined group were treated with both methods. The treatment in all three groups were done once every three days, twice a week, 4 weeks for a course of treatment, for a total of 1-3 courses. Then the therapeutic efficacy was evaluated using scores of visual analogue scale （VAS）, neck disability index （NDL） and clinical assessment scale （CAS） before treatment and after 1, 2 and 3 courses of treatment. Results： The scores of VAS, NDI and CAS in all three groups were significantly decreased after 1, 2 and 3 courses of treatment （all P〈0.001）, and there were no inter-group statistical significances in comparing scores of VAS, NDI and CAS （all P〉0.05）. Conclusion： Bloodletting and cupping share the similar effect with acupuncture in pain relief and improvement of quality of life in patients with cervical radiculopathy.展开更多
Objective： To observe the clinical effect of acupuncture therapy to support yang and consolidate the constitution for cervical spondylosis of vertebral artery type （CSA）. Methods： A total of 72 patients with CSA w...Objective： To observe the clinical effect of acupuncture therapy to support yang and consolidate the constitution for cervical spondylosis of vertebral artery type （CSA）. Methods： A total of 72 patients with CSA were randomly divided upon the random digital table into an acupuncture- moxibustion group and an acupuncture group, 36 cases in each group. The acupuncture-moxibustion group was treated by electroacupuncture （EA） at bilateral Fengchi （GB 20） and C4-6 Jiaji （EX-B 2）, in combination of moxibustion at Baihui （GV 20）, Shenshu （BL 23） and Mingmen （GV 4） to support yang and consolidate constitution. The acupuncture group was given by routine EA at bilateral Fengchi （GB 20）, cervical Jiaji （EX-B 2）, Tianzhu （BL 10）, Jianjing （GB 21）, Houxi （SI 3）, Hegu （LI 4） and Waiguan （TE 5）. The treatment was given once every day and continuous six sessions made one course. After 2-course treatment, the improved situation of clinical symptoms and clinical effect were observed in the two groups. Results： The total effective rate was 91.7% in the acupuncture-moxibustion group and 61.1% in the acupuncture group. The difference of the total effective rate between the two groups was statistically significant （P〈0.05）. After treatment, the scores of the clinical symptoms in the two groups were obviously decreased than those of the same group before treatment （P〈0.01）. The differences in the scores between the two groups were statistically significant （P〈0.05）. Conclusion： Acupuncture-moxibustion treatment to support yan~ and consolidate constitution is better than the routine acupuncture therapy in the therapeutic effect for CSA.展开更多
基金Supported by Science and Research Foundation of Shanghai Municipal Health Bureau (200537103)
文摘Objective: To examine the changes of mu-opioid receptors (MORs) expression in human chronic inflamed knee joint synovium tissue. Methods:Knee joint synovium tissues were taken from 21 patients with chronic arthritis (inflamed group) and 6 fresh bodies with normal knee joints (control group). And the expression of MORs was detected by using immunohistochemistry. flow cytometry(FCM) and reverse-transcription polymerase chain reaction (RT-PCR). Results: The expression of MORs in the inflamed group was significantly higher than that in the normal group by using the 3 techniques(P<0. 05). Conclusion: Chronic inflammation enhances the up-regulation of MORs in human knee joint synovium tissue.
文摘Objective: To observe the clinical effect of warm needling moxibustion plus acupoint sticking therapy for cervical radiculopathy. Methods: A total of 120 cases were allocated into an observation group, a warm needling group and an acupoint sticking group according to the random number table, with 40 cases in each group. Cases in the observation group received warm needling moxibustion plus acupoint sticking therapy;cases in the warm needling group received the same warm needling moxibustion in the observation group;cases in the acupoint sticking group received the same acupoint sticking therapy in the observation group. The scores of Japanese Orthopaedic Association (JOA) and visual analog scale (VAS) were recorded before and after treatment. Results: The total effective rate was 95.0% in the observation group, versus 77.5% in the warm needling group and 75.0% in the acupoint sticking group (both P<0.05). Inter-group differences in JOA and VAS between the observation group and the other two groups were statistically significant (all P<0.05). Conclusion: Warm needling moxibustion plus acupoint sticking therapy is effective in treating cervical radiculopathy, and it can significantly alleviate pain and enhance clinical efficacy, and thus is worth clinical popularization.
文摘Objective:To observe the clinical effect of Zheng's Jin Gou Diao Yu(gold-hook-fishing)acupuncture method versus ordinary acupuncture on superficial fascia for treating neck type cervical spondylopathy in Kyrgyz.Methods:A total of 64 Kyrgyz patients conforming to the diagnostic criteria of neck type cervical spondylopathy were included.The patients were randomized into a Zheng's Jin Gou Diao Yu(gold-hook-fishing)acupuncture group and a conventional acupuncture group,with 32 cases in each group.Patients in the Zheng's Jin Gou Diao Yu(gold-hook-fishing)acupuncture group were treated with Zheng's Jin Gou Diao Yu(gold-hook-fishing)acupuncture method to stimulate the superficial fascia,the stimulation sites were primarily located at bilateral sides of the cervical vertebra as well as the trigger points in shoulder-neck region;patients in the conventional acupuncture group were punctured at the same acupoints,with twirling reducing method,and the depth of insertion was determined by the treated region.Patients in both groups received treatment every day for a succession of 5 d as a course,with a 2-day interval between 2 courses,and the whole treatment lasted for 3 courses.After 3 courses of treatment,the McGill pain questionnaire(MPQ)and neck disability index(NDI)were measured to compare the clinical effect between the two groups.Results:After treatment,scores of MPQ and NDI scale dropped when compared with those before treatment,and the differences showed statistical significance(all P<0.05);scores of MPQ and NDI in the Jin Gou Diao Yu(gold-hook-fishing)acupuncture group were substantially lower than those in the conventional acupuncture group,and the differences showed statistical significance(all P<0.05).The total effective rate was 96.9%in the Jin Gou Diao Yu(gold-hook-fishing)acupuncture group and the cured rate was 78.1%,which were higher than 81.3%and 40.6%in the conventional acupuncture group,and the differences showed statistical significance(both P<0.05).Conclusion:Zheng's Jin Gou Diao Yu(gold-hook-fishing)acupuncture method by stimulating superficial fascia to treat cervical spondylopathy in Kyrgyz can produce a better clinical effect than conventional acupuncture treatment,and is effective in improving pain and stiffness in patients,and thus is worth clinical popularization.
基金supported by Scientific Research Project of Integrative Chinese and Western Medicine by Tianjin Municipal Health BureauNo.11027~~
文摘Objective： To observe the efficacy and safety of bloodletting and cupping for cervical radiculopathy. Methods： The randomized controlled clinical trial was conducted in five centers. A total of 183 eligible subjects were randomly allocated into a bloodletting group （n=68）, an acupuncture group （n=56） and a combined group （n=59）. Patients in the bloodletting group were treated with bloodletting at Dazhui （GV 14） and Jianjing （GB 21） on the affected side, coupled with 5-10 min of cupping, 5 mL blood for each cup, 2-3 cups for one treatment. Patients in the acupuncture group were treated with needling cervical Jiaji （EX-B 2） points and Jianjing （GB 21） on the affected side. The needles were retained for 30 min. Patients in the combined group were treated with both methods. The treatment in all three groups were done once every three days, twice a week, 4 weeks for a course of treatment, for a total of 1-3 courses. Then the therapeutic efficacy was evaluated using scores of visual analogue scale （VAS）, neck disability index （NDL） and clinical assessment scale （CAS） before treatment and after 1, 2 and 3 courses of treatment. Results： The scores of VAS, NDI and CAS in all three groups were significantly decreased after 1, 2 and 3 courses of treatment （all P〈0.001）, and there were no inter-group statistical significances in comparing scores of VAS, NDI and CAS （all P〉0.05）. Conclusion： Bloodletting and cupping share the similar effect with acupuncture in pain relief and improvement of quality of life in patients with cervical radiculopathy.
文摘Objective： To observe the clinical effect of acupuncture therapy to support yang and consolidate the constitution for cervical spondylosis of vertebral artery type （CSA）. Methods： A total of 72 patients with CSA were randomly divided upon the random digital table into an acupuncture- moxibustion group and an acupuncture group, 36 cases in each group. The acupuncture-moxibustion group was treated by electroacupuncture （EA） at bilateral Fengchi （GB 20） and C4-6 Jiaji （EX-B 2）, in combination of moxibustion at Baihui （GV 20）, Shenshu （BL 23） and Mingmen （GV 4） to support yang and consolidate constitution. The acupuncture group was given by routine EA at bilateral Fengchi （GB 20）, cervical Jiaji （EX-B 2）, Tianzhu （BL 10）, Jianjing （GB 21）, Houxi （SI 3）, Hegu （LI 4） and Waiguan （TE 5）. The treatment was given once every day and continuous six sessions made one course. After 2-course treatment, the improved situation of clinical symptoms and clinical effect were observed in the two groups. Results： The total effective rate was 91.7% in the acupuncture-moxibustion group and 61.1% in the acupuncture group. The difference of the total effective rate between the two groups was statistically significant （P〈0.05）. After treatment, the scores of the clinical symptoms in the two groups were obviously decreased than those of the same group before treatment （P〈0.01）. The differences in the scores between the two groups were statistically significant （P〈0.05）. Conclusion： Acupuncture-moxibustion treatment to support yan~ and consolidate constitution is better than the routine acupuncture therapy in the therapeutic effect for CSA.
