Theoretical studies on the electronic and geometric structures, the trend in DNA-binding affinities as well as the the structure-activity relationship (SAR) of a series of water-soluble Ru(II) methylimidazole comp...Theoretical studies on the electronic and geometric structures, the trend in DNA-binding affinities as well as the the structure-activity relationship (SAR) of a series of water-soluble Ru(II) methylimidazole complexes, i.e. [Ru(Mehn)4iip]^2+ (1) (MeIm=l-methylimidazole, iip=2-(1H-imidazo-4-group)-lH-imidazo[n,5-f][1,10]phenanthroline), [Ru(MeIm)4tip]^2+ (2) (tip=2-(thiophene-2-group)-lH-imidazo[4,5-f] [i,10]phenanthroline), and [Ru(Melm)42ntz]^2+ (3) (2ntz=2-(2-nitro-l,3-thiazole-5-group)-lH-imidazo[4,5-f][1,10]phenanthroline), were car- ried out using the density functional theory (DFT). The electronic structures of these Ru(II) complexes were analyzed on the basis of their geometric structures optimized in aqueous solution, and the trend in the DNA-binding constants (Kb) was reasonably explained. The results show that the replacement of imidazole ligand by thiophene ligand can effectively improve the DNA-binding affinity of the complex. Meanwhile, it was found that introduc- ing the stronger electronegative N atom and NO2 group on terminal loop of intercalative ligand can obviously reduce the complex's LUMO and HOMO-LUMO gap energies. Based on these findings, the designed complex [Ru(MeIm)42ntz]^2+ (3) can be expected to have the greatest Kb value in complexes 1-3. In addition, the structure-activity relationships and antitumor mechanism were also carefully discussed, and the antimetastatic activity of the designed complex 3 was predicted. Finally, the electronic absorption spectra of this series of complexes in aqueous solution were calculated, simulated and assigned using DFT/TDDFT methods as well as conductor-like polarizable continuum model (CPCM), and were in good agreement with the experimental results.展开更多
This paper discusses the primary causes from the point of synergistic effects to improve power system vulnerability in the power system planning and safety operation. Based on the vulnerability conception in the compl...This paper discusses the primary causes from the point of synergistic effects to improve power system vulnerability in the power system planning and safety operation. Based on the vulnerability conception in the complex network theory the vulnerability of the power system can be evaluated by the minimum load loss rate when considering power supply ability.Consequently according to the synergistic effect theory the critical line of the power system is defined by its influence on failure set vulnerability in N-k contingencies.The cascading failure modes are proposed based on the criterion whether the acceptable load curtailment level is below a preset value.Significant conclusions are revealed by results of IEEE 39 case analysis weak points of power networks and heavy load condition are the main causes of large-scale cascading failures damaging synergistic effects can result in partial failure developed into large-scale cascading failures vulnerable lines of power systems can directly lead the partial failure to deteriorate into a large blackout while less vulnerable lines can cause a large-scale cascading failure.展开更多
A new method for complex activity recognition in videos by key frames was presented. The progressive bisection strategy(PBS) was employed to divide the complex activity into a series of simple activities and the key f...A new method for complex activity recognition in videos by key frames was presented. The progressive bisection strategy(PBS) was employed to divide the complex activity into a series of simple activities and the key frames representing the simple activities were extracted by the self-splitting competitive learning(SSCL) algorithm. A new similarity criterion of complex activities was defined. Besides the regular visual factor, the order factor and the interference factor measuring the timing matching relationship of the simple activities and the discontinuous matching relationship of the simple activities respectively were considered. On these bases, the complex human activity recognition could be achieved by calculating their similarities. The recognition error was reduced compared with other methods when ignoring the recognition of simple activities. The proposed method was tested and evaluated on the self-built broadcast gymnastic database and the dancing database. The experimental results prove the superior efficiency.展开更多
Evaluation of the performance of existing support in underground tunnels is of great importance for production and interests.Based on field investigation,the shape and number of joints and fractures were investigated ...Evaluation of the performance of existing support in underground tunnels is of great importance for production and interests.Based on field investigation,the shape and number of joints and fractures were investigated in the mining area.Then,the stability of each structural blocks is analyzed by 3D wedge stability analysis software(Unwedge).Moreover,a new analysis method based on critical block theory is applied to analyze the stability of excavated laneways in continuous and discontinuous rock and monitor the stress changes in a fractured tunnel rock mass.The test results indicate that the 3D wedge stability analysis software for underground excavation can evaluate deep tunnel support.Besides,there is no direct relation between the size of the block and the instability of the tunnel.The support method,on large and thick key blocks,needs to be improved.In a broken tunnel section,U-shaped steel support can effectively promote the stress state of the surrounding rock.By monitoring the surrounding rock,it is proven that the vibrating string anchor stress monitoring system is an efficient and real-time method for tunnel stability evaluation.展开更多
In recent years,multiple-load automatic guided vehicle(AGV)is increasingly used in the logistics transportation fields,owing to the advantages of smaller fleet size and fewer occurrences of traffic congestion.However,...In recent years,multiple-load automatic guided vehicle(AGV)is increasingly used in the logistics transportation fields,owing to the advantages of smaller fleet size and fewer occurrences of traffic congestion.However,one main challenge lies in the deadlock-avoidance for the dispatching process of a multiple-load AGV system.To prevent the system from falling into a deadlock,a strategy of keeping the number of jobs in the system(NJIS)at a low level is adopted in most existing literatures.It is noteworthy that a low-level NJIS will make the processing machine easier to be starved,thereby reducing the system efficiency unavoidably.The motivation of the paper is to develop a deadlock-avoidance dispatching method for a multiple-load AGV system operating at a high NJIS level.Firstly,the deadlock-avoidance dispatching method is devised by incorporating a deadlock-avoidance strategy into a dispatching procedure that contains four sub-problems.In this strategy,critical tasks are recognized according to the status of workstation buffers,and then temporarily forbidden to avoid potential deadlocks.Secondly,three multiattribute dispatching rules are designed for system efficiency,where both the traveling distance and the buffer status are taken into account.Finally,a simulation system is developed to evaluate the performance of the proposed deadlock-avoidance strategy and dispatching rules at different NJIS levels.The experimental results demonstrate that our deadlock-avoidance dispatching method can improve the system efficiency at a high NJIS level and the adaptability to various system settings,while still avoiding potential deadlocks.展开更多
According to the consequences of software failures, software faults remaining in safety-critical systems can be classified into two sets: common faults and fatal faults. Common faults cause slight loss when they are ...According to the consequences of software failures, software faults remaining in safety-critical systems can be classified into two sets: common faults and fatal faults. Common faults cause slight loss when they are activated. A fatal fault can lead to significant loss, and even damage the safety-crltical system entirely when it is activated. A software reliability growth model for safety-critical systems is developed based on G - 0 model. And a software cost model is proposed too. The cost model considers maintenance and risk costs due to software failures. The optimal release policies are discussed to minimize the total software cost. A numerical exampie is provided to illustrate how to use the results we obtained.展开更多
The public-private partnership has been in use in the world for over 40 years, and has been growing at a varying rate and with mixed success in different countries. Based on the experience gained in selected countries...The public-private partnership has been in use in the world for over 40 years, and has been growing at a varying rate and with mixed success in different countries. Based on the experience gained in selected countries, this article shows key success factors of the public-private partnership.展开更多
Urban system is the spatial reflection of the inner-deep social economic movement. New economic circumstances not only make the evolution of urban system present one brand-new landscape, but also put forward a new sub...Urban system is the spatial reflection of the inner-deep social economic movement. New economic circumstances not only make the evolution of urban system present one brand-new landscape, but also put forward a new subject for planning of urban system. This article analyzes the properties of the traditional economic process and its essential effect on urban system; it makes a complete survey on the properties of new economic circumstances and its effect on re-forming of urban system; the complicated influential process and result are concluded into the aspects, such as new growth motive force, new economic organization, new location factor and new spatial phenomenon, and its inner effect mechanism in shown as well. In this article, the change process of urban system space is explained in four aspects: (1) dissimulation in the process of spatial agglomeration and diffusion; (2) change of “center-periphery” effect; (3) acceleration growth of axial regions; (4) re-forming of the world and regional urban system. Based on the above theoretical analysis and the properties & requests of new economic circumstances, this article finally puts forward four philosophies emphasized by urban system planning, and forms the new frame for drawing-up of urban system planning.展开更多
Based on the analysis of printed elliptical slot (PES) UWB antenna,a dual-banded PES antenna is designed for WLAN and UWB bands at 2.4 GHz.The design cooperates two important wireless commutation system antennas into ...Based on the analysis of printed elliptical slot (PES) UWB antenna,a dual-banded PES antenna is designed for WLAN and UWB bands at 2.4 GHz.The design cooperates two important wireless commutation system antennas into one printed antenna.In the design,a circular slot structure is presented,which is suitable for the band ejection.Characteristics of the designed antenna are analyzed and key parameters,such as S11,S21 and VSWR are measured.E-field distribution of the surface is simulated and analyzed.展开更多
A new business management mode-agile & convenient management mode (ACM) was proposed because of large scale mobile computing and mobile business. As an efficient approach to ACM, Mobile ERP (MERP), including its c...A new business management mode-agile & convenient management mode (ACM) was proposed because of large scale mobile computing and mobile business. As an efficient approach to ACM, Mobile ERP (MERP), including its concept and four-tier architecture was introduced firstly. Then, the two key technologies of implementing MERP about message service and wireless WAP service were developed. Meanwhile, an official MERP system was also implemented based on our CERP software system by aglets. And it was applied by Henan Tongli Cement Group in China. In comparison with the traditional ERP system, the new system could improve the efficiency and level of management, and reduce the management cost of enterprise.展开更多
In recent years, a number of organisations have implemented Executive Information Systems (EIS) including Computer-Based Information Systems (CBIS) in order to improve the performance of their executives' jobs th...In recent years, a number of organisations have implemented Executive Information Systems (EIS) including Computer-Based Information Systems (CBIS) in order to improve the performance of their executives' jobs though the majority of executives are unwilling to use EIS applications because of their design defects. Present researches on Executive Information Systems (EIS) are limited and less focused on the factors associated with EIS successful usage. This research adopts an extension of the Technology Acceptance Model (TAM) to derive useful variables to address the problem of the low usage of EIS by executives due to social factors, habits and facilitation conditions variables in Triandis' Framework. It reports on the adoption and usage of EIS by the executives in Organizations. The results show that experience in EIS usage was high with most respondents having used EIS for between 0 to 4 years (72.41%), followed by the 5-9 years group with 25.86%. However, in terms of ability to use EIS, most executives were at the expert (knowledgeable), casual user with 37.93%, followed by novice frequent user group with 31.03%. From this research, the authors propose a model that incorporates the habits, social factors and facilitating conditions in an Executive Information Systems.展开更多
In order to solve the distributed detection fusion problem of underwater target detection, when the signal to noise ratio (SNR) of the acoustic channel is low, a new strategy for united detection fusion and communicat...In order to solve the distributed detection fusion problem of underwater target detection, when the signal to noise ratio (SNR) of the acoustic channel is low, a new strategy for united detection fusion and communication using multiple sensors was proposed. The performance of detection fusion was studied and compared based on the Neyman-Pearson principle when the binary phase shift keying (BPSK) and on-off keying (OOK) modes were used by the local sensors. The comparative simulation and analysis between the optimal likelihood ratio test and the proposed strategy was completed, and both the theoretical analysis and simulation indicate that using the proposed new strategy could improve the detection performance effectively. In theory, the proposed strategy of united detection fusion and communication is of great significance to the establishment of an underwater target detection system.展开更多
基金ACKNOWLEDGMENTS This work was supported by the National Natural Science Foundation of China (No.20903027), the Natural Science Foundation of Guangdong Province of China (No.9452402301001941), the Medical Scientific Research Foundation of Guangdong Province of China (No.B2013297), and the University Student in Guangdong Province Innovation and Entrepreneurship Train ing Program (No.1057112019 and No.1057112013).
文摘Theoretical studies on the electronic and geometric structures, the trend in DNA-binding affinities as well as the the structure-activity relationship (SAR) of a series of water-soluble Ru(II) methylimidazole complexes, i.e. [Ru(Mehn)4iip]^2+ (1) (MeIm=l-methylimidazole, iip=2-(1H-imidazo-4-group)-lH-imidazo[n,5-f][1,10]phenanthroline), [Ru(MeIm)4tip]^2+ (2) (tip=2-(thiophene-2-group)-lH-imidazo[4,5-f] [i,10]phenanthroline), and [Ru(Melm)42ntz]^2+ (3) (2ntz=2-(2-nitro-l,3-thiazole-5-group)-lH-imidazo[4,5-f][1,10]phenanthroline), were car- ried out using the density functional theory (DFT). The electronic structures of these Ru(II) complexes were analyzed on the basis of their geometric structures optimized in aqueous solution, and the trend in the DNA-binding constants (Kb) was reasonably explained. The results show that the replacement of imidazole ligand by thiophene ligand can effectively improve the DNA-binding affinity of the complex. Meanwhile, it was found that introduc- ing the stronger electronegative N atom and NO2 group on terminal loop of intercalative ligand can obviously reduce the complex's LUMO and HOMO-LUMO gap energies. Based on these findings, the designed complex [Ru(MeIm)42ntz]^2+ (3) can be expected to have the greatest Kb value in complexes 1-3. In addition, the structure-activity relationships and antitumor mechanism were also carefully discussed, and the antimetastatic activity of the designed complex 3 was predicted. Finally, the electronic absorption spectra of this series of complexes in aqueous solution were calculated, simulated and assigned using DFT/TDDFT methods as well as conductor-like polarizable continuum model (CPCM), and were in good agreement with the experimental results.
基金The National Natural Science Foundation of China(No.51277028)
文摘This paper discusses the primary causes from the point of synergistic effects to improve power system vulnerability in the power system planning and safety operation. Based on the vulnerability conception in the complex network theory the vulnerability of the power system can be evaluated by the minimum load loss rate when considering power supply ability.Consequently according to the synergistic effect theory the critical line of the power system is defined by its influence on failure set vulnerability in N-k contingencies.The cascading failure modes are proposed based on the criterion whether the acceptable load curtailment level is below a preset value.Significant conclusions are revealed by results of IEEE 39 case analysis weak points of power networks and heavy load condition are the main causes of large-scale cascading failures damaging synergistic effects can result in partial failure developed into large-scale cascading failures vulnerable lines of power systems can directly lead the partial failure to deteriorate into a large blackout while less vulnerable lines can cause a large-scale cascading failure.
基金Project(50808025) supported by the National Natural Science Foundation of ChinaProject(20090162110057) supported by the Doctoral Fund of Ministry of Education,China
文摘A new method for complex activity recognition in videos by key frames was presented. The progressive bisection strategy(PBS) was employed to divide the complex activity into a series of simple activities and the key frames representing the simple activities were extracted by the self-splitting competitive learning(SSCL) algorithm. A new similarity criterion of complex activities was defined. Besides the regular visual factor, the order factor and the interference factor measuring the timing matching relationship of the simple activities and the discontinuous matching relationship of the simple activities respectively were considered. On these bases, the complex human activity recognition could be achieved by calculating their similarities. The recognition error was reduced compared with other methods when ignoring the recognition of simple activities. The proposed method was tested and evaluated on the self-built broadcast gymnastic database and the dancing database. The experimental results prove the superior efficiency.
基金Projects(51964007,51774101)supported by the National Natural Science Foundation of ChinaProject(2016-4011)supported by the High-level Innovative Talents Training Project in Guizhou Province,ChinaProject(2019-5619)supported by the Guizhou Mining Power Disaster Early Warning and Control Technology Innovation Team,China。
文摘Evaluation of the performance of existing support in underground tunnels is of great importance for production and interests.Based on field investigation,the shape and number of joints and fractures were investigated in the mining area.Then,the stability of each structural blocks is analyzed by 3D wedge stability analysis software(Unwedge).Moreover,a new analysis method based on critical block theory is applied to analyze the stability of excavated laneways in continuous and discontinuous rock and monitor the stress changes in a fractured tunnel rock mass.The test results indicate that the 3D wedge stability analysis software for underground excavation can evaluate deep tunnel support.Besides,there is no direct relation between the size of the block and the instability of the tunnel.The support method,on large and thick key blocks,needs to be improved.In a broken tunnel section,U-shaped steel support can effectively promote the stress state of the surrounding rock.By monitoring the surrounding rock,it is proven that the vibrating string anchor stress monitoring system is an efficient and real-time method for tunnel stability evaluation.
基金supported by the National Natural Science Foundation of China(Nos.52005427,61973154)the National Defense Basic Scientific Research Program of China(No.JCKY2018605C004)+1 种基金the Natural Science Research Project of Jiangsu Higher Education Institutions(Nos.19KJB510013,18KJA460009)the Foundation of Graduate Innovation Center in Nanjing University of Aeronautics and Astronautics(No.KFJJ20190516)。
文摘In recent years,multiple-load automatic guided vehicle(AGV)is increasingly used in the logistics transportation fields,owing to the advantages of smaller fleet size and fewer occurrences of traffic congestion.However,one main challenge lies in the deadlock-avoidance for the dispatching process of a multiple-load AGV system.To prevent the system from falling into a deadlock,a strategy of keeping the number of jobs in the system(NJIS)at a low level is adopted in most existing literatures.It is noteworthy that a low-level NJIS will make the processing machine easier to be starved,thereby reducing the system efficiency unavoidably.The motivation of the paper is to develop a deadlock-avoidance dispatching method for a multiple-load AGV system operating at a high NJIS level.Firstly,the deadlock-avoidance dispatching method is devised by incorporating a deadlock-avoidance strategy into a dispatching procedure that contains four sub-problems.In this strategy,critical tasks are recognized according to the status of workstation buffers,and then temporarily forbidden to avoid potential deadlocks.Secondly,three multiattribute dispatching rules are designed for system efficiency,where both the traveling distance and the buffer status are taken into account.Finally,a simulation system is developed to evaluate the performance of the proposed deadlock-avoidance strategy and dispatching rules at different NJIS levels.The experimental results demonstrate that our deadlock-avoidance dispatching method can improve the system efficiency at a high NJIS level and the adaptability to various system settings,while still avoiding potential deadlocks.
基金Sponsored by the Ph.D. Programs Foundation of Ministry of Education of China (Grant No. 20020213017).
文摘According to the consequences of software failures, software faults remaining in safety-critical systems can be classified into two sets: common faults and fatal faults. Common faults cause slight loss when they are activated. A fatal fault can lead to significant loss, and even damage the safety-crltical system entirely when it is activated. A software reliability growth model for safety-critical systems is developed based on G - 0 model. And a software cost model is proposed too. The cost model considers maintenance and risk costs due to software failures. The optimal release policies are discussed to minimize the total software cost. A numerical exampie is provided to illustrate how to use the results we obtained.
文摘The public-private partnership has been in use in the world for over 40 years, and has been growing at a varying rate and with mixed success in different countries. Based on the experience gained in selected countries, this article shows key success factors of the public-private partnership.
基金Under the auspices of the National Natural Science Foundation of China(No.40001007).
文摘Urban system is the spatial reflection of the inner-deep social economic movement. New economic circumstances not only make the evolution of urban system present one brand-new landscape, but also put forward a new subject for planning of urban system. This article analyzes the properties of the traditional economic process and its essential effect on urban system; it makes a complete survey on the properties of new economic circumstances and its effect on re-forming of urban system; the complicated influential process and result are concluded into the aspects, such as new growth motive force, new economic organization, new location factor and new spatial phenomenon, and its inner effect mechanism in shown as well. In this article, the change process of urban system space is explained in four aspects: (1) dissimulation in the process of spatial agglomeration and diffusion; (2) change of “center-periphery” effect; (3) acceleration growth of axial regions; (4) re-forming of the world and regional urban system. Based on the above theoretical analysis and the properties & requests of new economic circumstances, this article finally puts forward four philosophies emphasized by urban system planning, and forms the new frame for drawing-up of urban system planning.
基金Sponsored by the National Basic Research Program of China(Grant No.2007CB3106XX) and Qualcomm
文摘Based on the analysis of printed elliptical slot (PES) UWB antenna,a dual-banded PES antenna is designed for WLAN and UWB bands at 2.4 GHz.The design cooperates two important wireless commutation system antennas into one printed antenna.In the design,a circular slot structure is presented,which is suitable for the band ejection.Characteristics of the designed antenna are analyzed and key parameters,such as S11,S21 and VSWR are measured.E-field distribution of the surface is simulated and analyzed.
基金Sponsored by the Project Supported by the National High-Technology R&D Program for CIMS of China (Grant No2006AA04Z165)
文摘A new business management mode-agile & convenient management mode (ACM) was proposed because of large scale mobile computing and mobile business. As an efficient approach to ACM, Mobile ERP (MERP), including its concept and four-tier architecture was introduced firstly. Then, the two key technologies of implementing MERP about message service and wireless WAP service were developed. Meanwhile, an official MERP system was also implemented based on our CERP software system by aglets. And it was applied by Henan Tongli Cement Group in China. In comparison with the traditional ERP system, the new system could improve the efficiency and level of management, and reduce the management cost of enterprise.
文摘In recent years, a number of organisations have implemented Executive Information Systems (EIS) including Computer-Based Information Systems (CBIS) in order to improve the performance of their executives' jobs though the majority of executives are unwilling to use EIS applications because of their design defects. Present researches on Executive Information Systems (EIS) are limited and less focused on the factors associated with EIS successful usage. This research adopts an extension of the Technology Acceptance Model (TAM) to derive useful variables to address the problem of the low usage of EIS by executives due to social factors, habits and facilitation conditions variables in Triandis' Framework. It reports on the adoption and usage of EIS by the executives in Organizations. The results show that experience in EIS usage was high with most respondents having used EIS for between 0 to 4 years (72.41%), followed by the 5-9 years group with 25.86%. However, in terms of ability to use EIS, most executives were at the expert (knowledgeable), casual user with 37.93%, followed by novice frequent user group with 31.03%. From this research, the authors propose a model that incorporates the habits, social factors and facilitating conditions in an Executive Information Systems.
基金Supported by the National Natural Science Foundation of China under Grant No.60972152
文摘In order to solve the distributed detection fusion problem of underwater target detection, when the signal to noise ratio (SNR) of the acoustic channel is low, a new strategy for united detection fusion and communication using multiple sensors was proposed. The performance of detection fusion was studied and compared based on the Neyman-Pearson principle when the binary phase shift keying (BPSK) and on-off keying (OOK) modes were used by the local sensors. The comparative simulation and analysis between the optimal likelihood ratio test and the proposed strategy was completed, and both the theoretical analysis and simulation indicate that using the proposed new strategy could improve the detection performance effectively. In theory, the proposed strategy of united detection fusion and communication is of great significance to the establishment of an underwater target detection system.