Expression of opioid receptor-like receptor (ORL1)and its endogenous peptide agonist nociceptin/orphaninFo (N/OFQ) during mouse embryogenesis have been investigated. Transcripts of ORL1 and N/OFQ were detected by RT-P...Expression of opioid receptor-like receptor (ORL1)and its endogenous peptide agonist nociceptin/orphaninFo (N/OFQ) during mouse embryogenesis have been investigated. Transcripts of ORL1 and N/OFQ were detected by RT-PCR in mouse brain of day 8 embryo (E8)and the expression continued afterwards. Northern blotanalysis revealed abundant expression of ORL1 at postnatal day 1 (P1) and N/OFQ at E17 and P1 in the brain butnone was detected in other embryonic tissues. The presence of functional ORL1 in mouse embryonic brain wasalso confirmed by specific binding of [3H] N/OFQ (kd=1.3±0.5 nM and Bmax = 72±9 fmol/mg protein) as wellas by N/OFQ-stimulated G protein activation.展开更多
We investigate the quantum interference of spin wave excitations of a spin-1 atomic Bose condensate confined in an optical lattice. Single-channel and dual-channel interactions are employed in our system, and their in...We investigate the quantum interference of spin wave excitations of a spin-1 atomic Bose condensate confined in an optical lattice. Single-channel and dual-channel interactions are employed in our system, and their induced excitations are compared. Also we consider the interplay of magneto-optical excitations, which leads to a constructive or destructive effect for the creation of magnons based on background excitations. The population distributions of excited magnons can be well controlled by steering the long-range dipole-dipole interactions. Such a scheme can be used to demonstrate conventional quantum-optical phenomena like dynamical Casimir effect at finite temperatures.展开更多
文摘Expression of opioid receptor-like receptor (ORL1)and its endogenous peptide agonist nociceptin/orphaninFo (N/OFQ) during mouse embryogenesis have been investigated. Transcripts of ORL1 and N/OFQ were detected by RT-PCR in mouse brain of day 8 embryo (E8)and the expression continued afterwards. Northern blotanalysis revealed abundant expression of ORL1 at postnatal day 1 (P1) and N/OFQ at E17 and P1 in the brain butnone was detected in other embryonic tissues. The presence of functional ORL1 in mouse embryonic brain wasalso confirmed by specific binding of [3H] N/OFQ (kd=1.3±0.5 nM and Bmax = 72±9 fmol/mg protein) as wellas by N/OFQ-stimulated G protein activation.
基金Supported by the National Basic Research Program of China (973 Program) under Grant No. 2011CB921604+4 种基金the National Natural Science Foundation of China under Grant Nos. 11004057, 10828408Educational Commission of Henan Province of China under Grant No. 01026631082the “Chen Guang” Project Supported by Shanghai Municipal Education Commission and Shanghai Education Development Foundation under Grant No.10CG24
文摘We investigate the quantum interference of spin wave excitations of a spin-1 atomic Bose condensate confined in an optical lattice. Single-channel and dual-channel interactions are employed in our system, and their induced excitations are compared. Also we consider the interplay of magneto-optical excitations, which leads to a constructive or destructive effect for the creation of magnons based on background excitations. The population distributions of excited magnons can be well controlled by steering the long-range dipole-dipole interactions. Such a scheme can be used to demonstrate conventional quantum-optical phenomena like dynamical Casimir effect at finite temperatures.
