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医养结合视角下初级养老护理员胜任力模型的构建 被引量:21
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作者 杨丽 张京慧 +4 位作者 徐彬斌 唐四元 侯剑媚 马梦丹 师正坤 《中南大学学报(医学版)》 CAS CSCD 北大核心 2018年第6期679-684,共6页
目的:构建初级养老护理员胜任力模型,为初级养老护理员的选拔、考核和培训提供参考。方法:运用文献回顾法建立初级养老护理员胜任力初级模型;运用Delphi法对20名专家进行2轮函询,对初级模型各级指标进行修改与完善,并运用层次分析法和... 目的:构建初级养老护理员胜任力模型,为初级养老护理员的选拔、考核和培训提供参考。方法:运用文献回顾法建立初级养老护理员胜任力初级模型;运用Delphi法对20名专家进行2轮函询,对初级模型各级指标进行修改与完善,并运用层次分析法和专家排序法确定各级指标权重。结果:两轮函询问卷的有效回收率分别为87%和100%;专家权威系数为0.70~0.93,平均权威系数为0.80;最终确立的初级养老护理员胜任力模型包含4个一级指标、11个二级指标、37个三级指标。结论:所构建的初级养老护理员胜任力模型结果可靠,可作为初级养老护理员选拔、考核和培训的参考标准。 展开更多
关键词 结合模型 德尔菲法 老护理员 胜任力模型
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抗郁汤对孤养加慢性应激抑郁模型大鼠学习记忆能力及5-HT的影响 被引量:4
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作者 郝志红 李未韡 《中西医结合心脑血管病杂志》 2012年第8期975-976,共2页
目的探讨抗郁汤对孤养加慢性应激抑郁模型大鼠体重增长、学习记忆能力及脑内单胺类神经递质5-羟色胺(5-HT)含量的影响。方法除空白对照组普通喂养(群养)外,余各组制造孤养加慢性不可预见的中等强度刺激应激抑郁大鼠模型。连续21d于应激... 目的探讨抗郁汤对孤养加慢性应激抑郁模型大鼠体重增长、学习记忆能力及脑内单胺类神经递质5-羟色胺(5-HT)含量的影响。方法除空白对照组普通喂养(群养)外,余各组制造孤养加慢性不可预见的中等强度刺激应激抑郁大鼠模型。连续21d于应激刺激前30min除对照组外,余组接受不同灌胃干预,检测各组大鼠体重增长、学习记忆能力及5-HT含量。结果模型组大鼠体重增长、学习记忆能力及5-HT含量较空白对照组显著减少;抗郁汤低剂量组较模型组有所增加,盐酸氟西汀组与抗郁汤中、高剂量组接近空白对照组,较模型组显著增加。结论抗郁汤能够纠正抑郁模型大鼠体重降低、学习记忆能力,增高抑郁模型大鼠脑内单胺类神经递质5-HT含量,具有良好的抗抑郁功能,在一定剂量内存在一定的量效关系。 展开更多
关键词 抗郁汤 加慢性不可预见应激抑郁模型 单胺类神经递质
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异种血清对猪血管内皮细胞适应模型的影响
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作者 李孟彬 王为忠 +3 位作者 李开宗 张洪伟 季刚 沈新 《陕西医学杂志》 CAS 北大核心 2006年第11期1403-1404,1410,共3页
目的:观察胎牛血清对PAEC适应模型的影响。方法:以猪自体血清原代培养PAEC并传代,接种于96孔板后分别以5%正常人血清(NHS组)、胎牛血清(FCS组)和补体灭活的胎牛血清(FCS+C组)诱导6d,加入25%正常人血清,以MTT比色法检测细胞的存活率,并... 目的:观察胎牛血清对PAEC适应模型的影响。方法:以猪自体血清原代培养PAEC并传代,接种于96孔板后分别以5%正常人血清(NHS组)、胎牛血清(FCS组)和补体灭活的胎牛血清(FCS+C组)诱导6d,加入25%正常人血清,以MTT比色法检测细胞的存活率,并以免疫组化的方法观察各组HO-1的表达情况。结果:NHS组和FCS+C组细胞存活率均升高,同对照组相比差异显著,两组间亦有差异,HO-1表达均增加。FCS组与对照组无差异。结论:质量不佳的胎牛血清或补体灭活不充分的胎牛血清会干扰PAEC适应模型的诱导。 展开更多
关键词 内皮 血管/免疫学 移植 异种/免疫学 细胞培 养模型 动物 免疫组织 化学
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抑郁症动物模型研究进展 被引量:38
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作者 郭建友 李昌煜 葛卫红 《中国临床康复》 CSCD 2004年第10期1932-1933,共2页
抑郁症临床上可单发或继发于脑卒中等疾病之后,由于其发病机制至今尚未完全清楚,给抑郁症动物模型的研制带来很大的困难。应激动物模型,神经生化功能改变模型及孤养和分养模型等是目前常用的动物模型,但只表现出抑郁症的某些方面症状。... 抑郁症临床上可单发或继发于脑卒中等疾病之后,由于其发病机制至今尚未完全清楚,给抑郁症动物模型的研制带来很大的困难。应激动物模型,神经生化功能改变模型及孤养和分养模型等是目前常用的动物模型,但只表现出抑郁症的某些方面症状。转基因动物模型是一类很有希望的动物模型,能够比较全面地表现出抑郁症症状,逐渐成为抑郁症动物模型研究的热点。 展开更多
关键词 抑郁症 动物模型 应激模型 转基因模型 养模型
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四逆汤对抑郁症模型大鼠行为及脑内5-羟色胺含量的影响 被引量:2
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作者 崔恩胜 王晓钰 崔立 《兽医导刊》 2021年第14期216-218,共3页
目的:观察四逆汤对抑郁症模型大鼠行为及脑内5-羟色胺含量的影响,以评估其药效并初步探讨相关作用机理。方法:大鼠分为对照组、模型组、治疗组、四逆汤0.5g/kg、1 g/kg和2g/kg组。本研究使用孤养联合不可预知性行为学刺激来建造大鼠抑... 目的:观察四逆汤对抑郁症模型大鼠行为及脑内5-羟色胺含量的影响,以评估其药效并初步探讨相关作用机理。方法:大鼠分为对照组、模型组、治疗组、四逆汤0.5g/kg、1 g/kg和2g/kg组。本研究使用孤养联合不可预知性行为学刺激来建造大鼠抑郁症模型。通过糖水偏爱、强迫游泳、悬尾、敞箱实验等行为学测试,观察大鼠灌胃给予四逆汤后的行为学变化;同时测定大鼠大脑5-羟色胺含量。结果:(1)在悬尾和游泳测试中,四逆汤组和治疗组的放弃挣扎时间明显少于模型组。在糖水偏爱测试中,四逆汤灌胃给予后的动物表现出对糖水的摄入比例大于模型组动物。在敞箱测试中,四逆汤治疗组大鼠表现出更强的对陌生环境的探索精神,进入中央区域的时间和路程明显增多(2)抑郁症模型组大鼠的脑内5-HT的含量明显低于正常对照组,1g/kg及2g/kg剂量四逆汤灌胃治疗后的大鼠的脑组织中的神经递质5-HT的分布呈现出回升的趋势。结论:1g/kg及2g/kg剂量的四逆汤可以有效缓解抑郁症模型大鼠的行为学变化,并提高脑内5-HT的分布。 展开更多
关键词 四逆汤 抑郁症 伴随慢性应激模型 5-羟色胺
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对药香橼佛手对抑郁大鼠T细胞亚群的影响 被引量:9
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作者 宋美卿 冯玛莉 +3 位作者 马澜 贾力莉 牛艳艳 白崇智 《山西中医》 2015年第11期54-56,共3页
目的:观察行气疏肝对药香橼佛手对抑郁大鼠T细胞亚群的影响。方法:用慢性不可预见轻度应激抑郁症动物模型(CUMS)配合孤养的方法造模,将造模成功大鼠分为模型组、氟西汀阳性组、香佛对药水提组和醇提物组,外加空白对照组。通过体重、糖... 目的:观察行气疏肝对药香橼佛手对抑郁大鼠T细胞亚群的影响。方法:用慢性不可预见轻度应激抑郁症动物模型(CUMS)配合孤养的方法造模,将造模成功大鼠分为模型组、氟西汀阳性组、香佛对药水提组和醇提物组,外加空白对照组。通过体重、糖水偏爱率、旷场试验、脾和胸腺脏器指数及T细胞亚群(CD3+、CD4+、CD8+)各项指标评价对药香橼佛手对抑郁大鼠细胞免疫功能的影响。结果:CUMS配合孤养模型造模后体重、糖水偏爱率、旷场试验各项指标均显著低于空白对照组(P<0.05,P<0.01,P<0.001);对药香佛水提组体重、水提和醇提组糖水偏爱率及两组旷场试验水平运动明显高于模型对照组(P<0.05,P<0.01,P<0.01,P<0.05,P<0.05),且两组间无差异;模型对照组胸腺指数、CD3+、CD4+、CD4+/CD8+均显著低于空白对照组(P<0.001,P<0.001,P<0.001,P<0.05);对药香佛水提组CD3+与醇提组CD3+、CD4+百分率显著高于模型对照组(P<0.05,P<0.01,P<0.05)。结论:对药香佛水提和醇提组对抑郁大鼠体重、糖水偏爱率、旷场试验水平运动有增高作用,且两组间无差异;抑郁大鼠免疫系统胸腺指数及T淋巴细胞亚群(CD3+、CD4+、CD4+/CD8+)水平低下;对药香佛水提和醇提物对抑郁大鼠T细胞亚群(CD3+、CD4+)有增高作用且两者间无差异。 展开更多
关键词 抑郁症 香橼对药佛手 CUMS配合孤养模型 T细胞亚群 实验研究
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CRH在正常与抑郁症大鼠皮质分布的研究 被引量:1
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作者 唐晓伟 陈晓杰 +2 位作者 胡铁中 刘晓庆 刘文 《滁州学院学报》 2010年第5期32-34,共3页
以SD雄性大鼠为材料,采用慢性轻度不可预见性应激+孤养方法复制大鼠抑郁模型,比较促肾上腺皮质激素释放激素(CRH)免疫阳性神经元在大鼠大脑皮质的区域分布特征。结果显示:CRH免疫阳性神经元在皮层的各层均有分布;与对照组(NC组)相比,模... 以SD雄性大鼠为材料,采用慢性轻度不可预见性应激+孤养方法复制大鼠抑郁模型,比较促肾上腺皮质激素释放激素(CRH)免疫阳性神经元在大鼠大脑皮质的区域分布特征。结果显示:CRH免疫阳性神经元在皮层的各层均有分布;与对照组(NC组)相比,模型组(MC组)大鼠CRH免疫阳性细胞在大脑皮质的运动皮质(M)、感觉皮质(S)、听皮质(Au)、梨形皮质(Pir)显著增加,嗅皮质(Ol)也有增加但不明显。结论:CRH免疫反应阳性细胞在大脑皮层内广泛分布,抑郁大鼠CRH在皮质的表达增加,提示其可能参与应激反应。 展开更多
关键词 促肾上腺皮质激素释放激素 慢性轻度不可预见性应激 养模型 免疫组织化学 大脑皮质 大鼠
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Research on Yield and Quality of Hybrid Rice under Efficient Application Amount of Phosphorus and Potassium 被引量:3
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作者 熊洪 徐富贤 +4 位作者 朱永川 张林 郭晓艺 刘茂 周兴兵 《Agricultural Science & Technology》 CAS 2012年第2期343-350,共8页
[Objective] Application of P and K was not reasonable in southwest rice producing area, with no effective method for guiding application of P and K. This study aimed to conduct experiments with the same N application ... [Objective] Application of P and K was not reasonable in southwest rice producing area, with no effective method for guiding application of P and K. This study aimed to conduct experiments with the same N application and different P and K application in different ecological points, to explore a scientific and efficient management method of P and K nutrients and provide guidance for application of P and K in rice production. [Method] Hybrid rice Chuanxiang9838 was used as experimental material to study the relationship among application amount of P and K, utilization rates of P and K, rice yield and rice quality in seven ecological points of four provinces (municipalities) including Sichuan, Chongqing, Yunnan and Guizhou. The application amount per hectare of P was 37.5, 75, 112.5 and 150 kg, respectively; the application amount per hectare of K was 45, 135 and 180 kg, respectively. A total of 10 treatments were set for split-plot design with three replications. [Result] Yield of Chuanxiang9838 significantly varied in different experimental locations and under different levels of P and K, interaction of ecological point and different P and K treatments varied significantly. Yield had reached the maximum in ecological point of Yunnan Binchuan and in treatment with application of N 150 kg P 75 kg K 90 kg. Efficient utilization rates of P and K varied in each ecological point, efficient application amount of P and K in Sichuan Dongpo, Sichuan Luxian, Guizhou Xiaohe and Chongqing Yongchuan was the same, while that in Sichuan Guanghan, Sichuan Zhongjiang and Yunnan Binchuan was different. The main objective of high-yield rice production was to increase the number of effective panicles per hectare and seed setting rate. Rice quality was clustered into 2 categories by locations and 6 categories by treatments. [Conclusion] Prediction models of efficient application of P and K in rice production were established, which provided guidance for high-yield rice production and rational and efficient utilization of P and K in southwest rice area. 展开更多
关键词 Phosphorus and potassium nutrients Efficient application amount Mathematic model Mid-season hybrid rice
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Porcine Breeding Management in a Large-scale Piggery with Microbial Fermentation Bed 被引量:1
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作者 刘波 李兆龙 +6 位作者 唐建阳 黄勤楼 郑回勇 蓝江林 史怀 翁伯琦 余文权 《Agricultural Science & Technology》 CAS 2015年第1期160-166,171,共8页
[Objective] The behavior of eating, drinking, defecating and peeing of 1 500 pigs in a large-scale microbial fermentation bed-equipped piggery was observed. We hoped to find some simple indicators that could reflect t... [Objective] The behavior of eating, drinking, defecating and peeing of 1 500 pigs in a large-scale microbial fermentation bed-equipped piggery was observed. We hoped to find some simple indicators that could reflect the health status of swinery and to provide experience for the swinery performance management in large-scale microbial fermentation bed-equipped piggery. [Method] The body weight (BW), daily BW gain, feed intake and other indicators of different-day-old pigs were recorded in details. Based on the recorded data, the models between BW, BW gain, average daily feed intake and feed/gain ratio and growth days (d) were established. In addition, the incidences of pox-like macula (dermatitis), diarrhea (gastrointestinal disease), cough (respiratory disease), stiff pig (malnutrition), conjunctivitis (eye disease) and foot inflection (trauma) among fattening pigs were also investigated. [Result] The BW range, average BW, daily BW gain, breeding days, daily feed intake range, average daily feed intake, staged feed intake, accumulated feed intake, feed/gain ratio and accumulated feed/gain ratio of different-day-old pigs were studied, respectively. Four dynamic models were established for the growth of pigs: (1) the BW (y)-age (x) mod- el: y=0.758 9x-19.883 (3=0.993 7); (2) the BW gain (y)-age (x) model: y=1.039 5x05051 (F=0.885 4); (3) the average daily feed intake (y)-age (x) model: y=0.023 5x-0.334 3 (F=0.991 7); (4) the feed/gain ratio (y)-age (x) model: y=0.022x+0.427 8 (P=0.988 5). Based on these models, the corresponding theoretical growth value of pigs at different growth stage could be predicted. The main diseases occurred among the swinery in the large-scale microbial fermentation bed piggery included pox-like macula (dermatitis), diarrhea (gastrointestinal disease), cough (respiratory disease), stiff pig (mal- nutrition), conjunctivitis (eye disease) and foot inflection (trauma). The deadly infec- tious diseases had been not found among the pigs. [Conclusion] When the actual BW, BW gain, average daily feed intake and feed/gain ratio were all lower than the theoretical values predicted by the models, the management should be enhanced. The average daily feed intake of 60 to 65-day-old pigs was lower than the theoretic value, indicating that the pigs could not adapt nicely to the fermentation bed at the very early stage. When the pigs grew up to 70 to 75 d old, the average daily feed intake was higher than the theoretical value, indicating that the pigs had adapted to the fermentation bed. In particularly, average daily feed intake of 75-day-old pigs was higher than the theoretical value by 21%. It was suggested the fermentation bed was conducive to the growth of pigs. Considering the occurrence of diseases among pigs, the overall incidence was relatively low. The incidence of each disease was all lower than 10% with little difficulty in treating. If the management of mattress was strength- ened, such as paying attention to feeding and keeping water clean, many diseases could heal by themselves. 展开更多
关键词 Disease investigation Large-scale breeding Microbial fermentation bed Porcine growth model
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Transitions of Normal Universities and Strategies of Talents Cultivation 被引量:1
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作者 李旸 马建辉 贾砚萍 《Sino-US English Teaching》 2006年第6期60-63,共4页
Transitions of normal universities in our country are inexorable trends with the development of the times. In this process, normal universities should actively reform models of talents cultivation, establish teachers... Transitions of normal universities in our country are inexorable trends with the development of the times. In this process, normal universities should actively reform models of talents cultivation, establish teachers' profession with distinguishing features, construct new strategies of talents cultivation so as to improve all-round capacities of normal universities in running schools. 展开更多
关键词 normal universities TRANSITIONS MODELS strategies of talents cultivation
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On the Training Modes of Interdisciplinary and Application-oriented Talents of Business English 被引量:3
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作者 郝钦海 《Sino-US English Teaching》 2006年第8期7-11,共5页
This paper focuses on the training modes of interdisciplinary and application-oriented talents of business English and the constructions of curriculum. In the light of our socialist market-oriented economy characteris... This paper focuses on the training modes of interdisciplinary and application-oriented talents of business English and the constructions of curriculum. In the light of our socialist market-oriented economy characteristics, the discussion proceeds, in theory and practice, by putting forward a relatively profound approach according to the trend in the demands for business English talents and to the operational patterns of business English discipline, with some suggestions about the training modes of interdisciplinary and application-oriented talents and the construction of curriculum. 展开更多
关键词 business English interdisciplinary and application-oriented talents training modes CURRICULUM
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唯象兽医学概论(五)
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作者 向春涛 《四川畜牧兽医》 2005年第8期57-57,共1页
关键词 唯象兽医学 干支运气模型 系统功能病理模型 结合系统模型 诊断 中兽医
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“科学管理”中的效率工资研究 被引量:1
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作者 江若尘 《淮南工业学院学报(社会科学版)》 2000年第2期30-35,共6页
阐述了两种磨洋工 :由于天性趋向于轻松随便的“本性磨洋工”和为谋求个人利益极大化的“故意磨洋工”。综述了解决磨洋工的几个递进的解决方法 :计件工资与工时研究法、纵向相对业绩比较法、横向相对业绩比较法 (锦标制度 )和效率工资... 阐述了两种磨洋工 :由于天性趋向于轻松随便的“本性磨洋工”和为谋求个人利益极大化的“故意磨洋工”。综述了解决磨洋工的几个递进的解决方法 :计件工资与工时研究法、纵向相对业绩比较法、横向相对业绩比较法 (锦标制度 )和效率工资法 。 展开更多
关键词 本性磨洋工 故意磨洋工 计件工资和工时研究 相对业绩比较 效率工资 高薪防懒模型 高薪模型
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Application of the Nutrient Cycling Model NuCM to a Forest Monitoring Site Exposed to Acidic Precipitation in China 被引量:4
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作者 ZHU Jian-Hua YU Peng-Tao +2 位作者 T. A. SOGN WANG Yan-Hui J. MULDER 《Pedosphere》 SCIE CAS CSCD 2008年第6期681-690,共10页
The nutrient cycling model NuCM is one of the most detailed models for simulating processes that influence nutrient cycling in forest ecosystems. A field study was conducted at Tieshanping, a Masson pine (Pinus masson... The nutrient cycling model NuCM is one of the most detailed models for simulating processes that influence nutrient cycling in forest ecosystems. A field study was conducted at Tieshanping, a Masson pine (Pinus massoniana Lamb.) forest site, in Chongqing, China, to monitor the impacts of acidic precipitation on nutrient cycling. NuCM simulations were compared with observed data from the study site. The model produced an approximate fit with the observed data. It simulated the mean annual soil solution concentrations in the two simulation years, whereas it sometimes failed to reproduce seasonal variation. Even though some of the parameters required by model running were measured in the field, some others were still highly uncertain and the uncertainties were analyzed. Some of the uncertain parameters necessary for model running should be measured and calibrated to produce a better fit between modeled results and field data. 展开更多
关键词 acid rain forest soil nutrient cycling model simulation
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Coupling of an Individual-Based Model of Anchovy with Lower Trophic Level and Hydrodynamic Models 被引量:2
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作者 WANG Yuheng WEI Hao Michio J. Kishi 《Journal of Ocean University of China》 SCIE CAS 2013年第1期45-52,共8页
Anchovy (Engraulis aponicus), a small pelagic fish and food of other economic fishes, is a key species in the Yellow Sea ecosystem. Understanding the mechanisms of its recruitment and biomass variation is important ... Anchovy (Engraulis aponicus), a small pelagic fish and food of other economic fishes, is a key species in the Yellow Sea ecosystem. Understanding the mechanisms of its recruitment and biomass variation is important for the prediction and management of fishery resources. Coupled with a hydrodynamic model (POM) and a lower trophic level ecosystem model (NEMURO), an individual-based model of anchovy is developed to study the influence of physical environment on anchovy's biomass variation, Seasonal variations of circulation, water temperature and mix-layer depth from POM are used as external forcing for NEMURO and the anchovy model. Biomasses of large zooplankton and predatory zooplankton which anchovy feeds on are output from NEMURO and are controlled by the consumption of anchovy on them. Survival fitness theory related to temperature and food is used to determine the swimming action of anchovy in the model. The simulation results agree well with observations and elucidate the influence of temperature in over-wintering migration and food in feeding migration. 展开更多
关键词 ANCHOVY individual-based model population dynamics Yellow Sea
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Effect Research of Immobilized Algae-bacteria Removal Ammonia Nitrogen of Aquaculture Wastewater and Proposed Model 被引量:14
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作者 邹万生 张景来 +1 位作者 刘良国 邓武军 《Agricultural Science & Technology》 CAS 2010年第5期117-120,共4页
Applied Immobilized algae bacteria (ABI) to remove ammonia of freshwater aquaculture wastewater. Temperature (T),PH,light intensity (I),dissolved oxygen (DO) and filling rate five factors plays important role in the p... Applied Immobilized algae bacteria (ABI) to remove ammonia of freshwater aquaculture wastewater. Temperature (T),PH,light intensity (I),dissolved oxygen (DO) and filling rate five factors plays important role in the process of ammonia nitrogen removal ,related data between ammonia removal and five factors was received through multi-factor orthogonal test,and established relations model between the five factor and nitrogen removal. The results show that five-factors had significant effect on AR,and the best combinations for removing AR was temperature 30 ℃,pH=7.0,light intensity 6 000 lux,dissolved oxygen 5.0 mg/L and the fill rate 10%. According to the experimental data,equation model was proposed and coefficient of determination R2 =0.864 8,P<0.05. Samples T-test was done between the model predictions and the actual measured values.Test results showed that the significant difference of overall mean value sig. (2-tailed) was 0.978 (P>0.05),it Shows that had no significant difference between model predictions and the actual measured value,and model had a high degree of fitting. 展开更多
关键词 Immobilized Algae-bacteria Aquaculture wastewater Ammonia remove rate Proposed model
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Effect of parenteral and early intrajejunal nutrition on pancreatic digestive enzyme synthesis, storage and discharge in dog models of acute pancreatitis 被引量:6
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作者 Huan-Long Qin Zhen-Dong Su Lei-Guang Hu Zai-Xian Ding Qing-Tian Lin 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第7期1123-1128,共6页
AIM: To study the effect of early intrajejunal nutrition on enzyme-protein synthesis and secretion during acute pancreatitis. METHODS: Fifteen dogs were randomly divided into parenteral nutrition (n = 7) and early... AIM: To study the effect of early intrajejunal nutrition on enzyme-protein synthesis and secretion during acute pancreatitis. METHODS: Fifteen dogs were randomly divided into parenteral nutrition (n = 7) and early intrajejunal nutrition groups (n = 8). An acute pancreatitis model was induced by injecting 5% sodium taurocholate and trypsin into the pancreas via the pancreatic duct. Intrajejunal nutrition was delivered with a catheter via a jejunostomy tube after the model was established for 24 h. On d 1 and 7 and at the beginning of nutritional support, radioactive tracing and electron microscopes were used to evaluate the enzyme-protein synthesis in acinar cells, the subcellular fractionation and the change in zymogen granules after 1.85 × 10^6 Bq L-3H phenylalanine was infused at 30, 60, 120, and 180 min. RESULTS: The 3H radioactivity in pancreatic acinar cells reached its peak level at 60 min, and the contents in the early intrajejunal nutrition group were higher than those in the parenteral nutrition group, which were then decreased. The mean number and area of zymogen granules did not show any significant statistical difference in both groups on d i or on d 7 (P 〉 0.05). CONCLUSION: Early intrajejunal nutrition might be effective in dogs with acute pancreatitis. 展开更多
关键词 Parenteral nutrition Enteral nutrition Digestive enzyme Acute pancreatitis
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Application of Matter-element Model in Soil Nutrient Evaluation of Ecological Fragile Region 被引量:2
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作者 TANG Jie WANG Chenye +3 位作者 LIN Nianfeng LI Zhaoyang LI Haiyi MAO Zilong 《Chinese Geographical Science》 SCIE CSCD 2009年第2期168-176,共9页
On the basis of the soil environment investigation in Da'an City, Jilin Province, China, 40 soil samples from main land use types were obtained and tested by standard method. Soil organic matter (SOM), total N (TN... On the basis of the soil environment investigation in Da'an City, Jilin Province, China, 40 soil samples from main land use types were obtained and tested by standard method. Soil organic matter (SOM), total N (TN), total P (TP), total K (TK), available N (AN), available P (AP) and available K (AK) were chosen as the evaluation factors. A regional soil nutrient evaluation model was developed based on the matter-element model. The results show that the soil samples with nutrient grade Ⅱ-Ⅴ respectively account for 10%, 30%, 32.5% and 27.5%, and those with grade Ⅳ and Ⅴ account for 60% in all samples. The relationship between soil nutrients and land types indicates that the nutrients of farmland are relatively good, with 41.7% of soil samples with the nutrient grade Ⅳ and Ⅴ. The nutrients of saline-alkali land and sandy land are the worst, with 100% of soil samples with the nutrient grade IV and V. And the ratios of soil samples grade IV and V in grassland and wasteland are respectively 62.5 % and 54.55%. Generally speaking, the soil nutrients status in Da'an City is poor, 60% of soil samples are in poor and extremely poor conditions, indicating that the soil has been severely eroded. Being a relatively superior evaluation method with more accurate resuits and spatial distribution consistency, matter-element analysis is more suitable for regional soil nutrient evaluation than previous models. 展开更多
关键词 soil nutrient evaluation matter-element model extension engineering theory ecological fragile region
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Comparison of Artificial Neural Networks,Geographically Weighted Regression and Cokriging Methods for Predicting the Spatial Distribution of Soil Macronutrients(N,P,and K) 被引量:7
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作者 Samad EMAMGHOLIZADEH Shahin SHAHSAVANI Mohamad Amin ESLAMI 《Chinese Geographical Science》 SCIE CSCD 2017年第5期747-759,共13页
Soil macronutrients(i.e. nitrogen(N), phosphorus(P), and potassium(K)) are important soils components and knowing the spatial distribution of these parameters are necessary at precision agriculture. The purpose of thi... Soil macronutrients(i.e. nitrogen(N), phosphorus(P), and potassium(K)) are important soils components and knowing the spatial distribution of these parameters are necessary at precision agriculture. The purpose of this study was to evaluate the feasibility of different methods such as artificial neural networks(ANN) and two geostatistical methods(geographically weighted regression(GWR) and cokriging(CK)) to estimate N, P and K contents. For this purpose, soil samples were taken from topsoil(0–30 cm) at 106 points and analyzed for their chemical and physical parameters. These data were divided into calibration(n = 84) and validation(n = 22). Chemical and physical variables including clay, p H and organic carbon(OC) were used as auxiliary soil variables to estimate the N, P and K contents. Results showed that the ANN model(with coefficient of determination R^2 = 0.922 and root mean square error RMSE = 0.0079%) was more accurate compared to the CK model(with R^2 = 0.612 and RMSE = 0.0094%), and the GWR model(with R^2 = 0.872 and RMSE = 0.0089%) to estimate the N variable. The ANN model estimated the P with the RMSE of 3.630 ppm, which was respectively 28.93% and 20.00% less than the RMSE of 4.680 ppm and 4.357 ppm from the CK and GWR models. The estimated K by CK, GWR and ANN models have the RMSE of 76.794 ppm, 75.790 ppm and 52.484 ppm. Results indicated that the performance of the CK model for estimation of macro nutrients(N, P and K) was slightly lower than the GWR model. Also, the accuracy of the ANN model was higher than CK and GWR models, which proved to be more effective and reliable methods for estimating macro nutrients. 展开更多
关键词 precision agriculture soil characteristics INTERPOLATION artificial neural networks geographically weighted regression COKRIGING
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D-β-hydroxybutyrate inhibits microglial activation in a cell activation model in vitro 被引量:1
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作者 Xu Xudong Zhang Qing Tu Jianqi Ren Zhenfeng 《Journal of Medical Colleges of PLA(China)》 CAS 2011年第3期117-127,共11页
Microglial activation plays an important role in a panel of neurological disorders such as multiple sclerosis(MS) and Parkinson's disease(PD),and is a key target for developing therapeutic strategies for these dis... Microglial activation plays an important role in a panel of neurological disorders such as multiple sclerosis(MS) and Parkinson's disease(PD),and is a key target for developing therapeutic strategies for these diseases.Ketogenic diet (KD),which is able to inhibit microglial activation in substantia nigra pars compacta of mice,has been shown effective in a mouse model of PD,possibly through increasing D-β-hydroxybutyrate(D-β-HB),a major component of ketone bodies.To verify this,we developed an in vitro model of microglia activation with a microglia line,BV-2,and investigated how D-β-HB have an effect on the LPS-stimulated BV-2 cells.We found D-β-HB is able to recover the cell viability,and inhibit the production of inflammatory mediators and cytokines such as ROS,nitrite,IL-1β,TNF-α,and IL-6,which otherwise were increased in LPS-stimulated BV-2 cells.We conclude that the LPS induced BV-2 cells activation is a valid in vitro model of microglia activation.D-β-HB is able to suppress the activation of BV-2 cells, which might account for one of the possible reasons of KD therapy on the PD model. 展开更多
关键词 Microglial activation D-13-hydroxybutyrate LIPOPOLYSACCHARIDE Reactive oxygen species NO IL-1Β TNF-α IL-6
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